Bgee is a database to retrieve and compare gene expression patterns in multiple animal species, produced from multiple data types (RNA-Seq, Affymetrix, in situ hybridization, and EST data). Bgee is based exclusively on curated "normal", healthy, expression data (e.g., no gene knock-out, no treatment, no disease), to provide a comparable reference of normal gene expression. Bgee produces calls of presence/absence of expression, and of differential over-/under-expression, integrated along with information of gene orthology, and of homology between organs. This allows comparisons of expression patterns between species.
More information is provided in the documentation.
Our main interest is in the evolution of animal genomes in the context of organismal function and development. We have special interests in the early evolution of chordates and fishes. We have the aim of producing a database useful to disciplines such as comparative genomics, Evo-Devo, or transcriptome studies, whilst providing an improved integration of homology and related concepts into bioinformatics through ontologies and ontology tools.
To the extent possible under law, Bgee team has waived all copyright and related or neighboring rights to Bgee project. This work is published under the Creative Commons Zero license (CC0) from Switzerland. Although CC0 doesn’t legally require users of the data to cite the source, if you intend to use data from Bgee, it would be nice to cite us.
Any third party material on this site is the property of its original copyright holders; see notably "information about original images" at the bottom of our homepage for the animal photos copyright.
Our pipeline source code, as well as our curation and ontology resources can be browsed on our GitHub page.
More information about data analyses and database content is available in the documentation.