Gene: TOP1 - ENSACAG00000010889 - Anolis carolinensis (green anole)

General information

Ensembl ID	ENSACAG00000010889
Name	TOP1
Description	topoisomerase (DNA) I [Source:HGNC Symbol;Acc:HGNC:11986]
Organism	Anolis carolinensis (green anole)
Orthologs(s)	18 orthologs
Paralog(s)	1 paralogs

Expression

Anat. entity ID	Anatomical entity	Developmental stage(s)	Rank score	Expression score	Sources
UBERON:0005417	forelimb bud	[+] 1 stage UBERON:0000068embryo stage	489 489	97.58 97.58	AEIR AEIR
UBERON:0007144	embryonic post-anal tail	[+] 1 stage UBERON:0000068embryo stage	594 594	97.05 97.05	AEIR AEIR
UBERON:0005418	hindlimb bud	[+] 1 stage UBERON:0000068embryo stage	740 740	96.33 96.33	AEIR AEIR
UBERON:0008812	hemipenis	[+] 1 stage UBERON:0000068embryo stage	1.02e3 1.02e3	94.92 94.92	AEIR AEIR
UBERON:0000473	testis	[+] 1 stage UBERON:0000113post-juvenile adult stage	1.35e3 1.35e3	93.33 93.33	AEIR AEIR
UBERON:0000992	female gonad	[+] 1 stage UBERON:0000104life cycle	1.35e3 1.35e3	93.29 93.29	AEIR AEIR
UBERON:1000003	dewlap	[+] 1 stage UBERON:0000104life cycle	1.57e3 1.57e3	92.19 92.19	AEIR AEIR
UBERON:0002369	adrenal gland	[+] 1 stage UBERON:0000104life cycle	1.77e3 1.77e3	91.24 91.24	AEIR AEIR
UBERON:0000948	heart	[+] 2 stages UBERON:0000104life cycle UBERON:0000113post-juvenile adult stage	2.57e3 2.57e3 5.22e3	87.24 87.24 74.10	AEIR AEIR AEIR
UBERON:0002048	lung	[+] 1 stage UBERON:0000104life cycle	2.90e3 2.90e3	85.63 85.63	AEIR AEIR
UBERON:0001134	skeletal muscle tissue	[+] 2 stages UBERON:0000104life cycle UBERON:0000113post-juvenile adult stage	3.41e3 3.41e3 4.06e3	83.08 83.08 79.85	AEIR AEIR AEIR
UBERON:0002107	liver	[+] 1 stage UBERON:0000104life cycle	4.23e3 4.23e3	79.00 79.00	AEIR AEIR
UBERON:0000955	brain	[+] 2 stages UBERON:0000113post-juvenile adult stage UBERON:0000104life cycle	4.42e3 4.42e3 4.44e3	78.06 78.06 77.94	AEIR AEIR AEIR
UBERON:0002113	kidney	[+] 1 stage UBERON:0000113post-juvenile adult stage	5.32e3 5.32e3	73.61 73.61	AEIR AEIR

Sources
A	Affymetrix
E	EST
I	In Situ
R	RNA-Seq

data

no data

Rank scores
3.25e4	lightgrey: low confidence scores
	important score variation

Rank scores of expression calls are normalized across genes, conditions and species. Low score means that the gene is highly expressed in the condition. Max rank score in all species: 4.10e4. Min rank score varies across species.

Expression scores of expression calls use the minimum and maximum Rank of the species to normalize the expression to a value between 0 and 100. Low score means that the gene is lowly expressed in the condition.

Sources of annotations to anatomy and development:

RNA-Seq data: Bgee

Sources of raw data:

RNA-Seq data: GEO

Orthologs

Taxon name	Species with orthologs	Gene(s)	Expression comparison	See details
Sauria	1 species Gallus gallus (chicken)	1 gene ENSGALG00000003681 TOP1	Compare expression	[+]
Amniota	16 species Homo sapiens (human) Mus musculus (mouse) Pan troglodytes (chimpanzee) Gorilla gorilla (gorilla) Macaca mulatta (macaque) Rattus norvegicus (rat) Bos taurus (cattle) Sus scrofa (pig) Equus caballus (horse) Oryctolagus cuniculus (rabbit) Canis lupus familiaris (dog) Felis catus (cat) Cavia porcellus (guinea pig) Erinaceus europaeus (hedgehog) Ornithorhynchus anatinus (platypus) Gallus gallus (chicken)	16 genes ENSG00000198900 TOP1 ENSMUSG00000070544 Top1 ENSPTRG00000013498 TOP1 ENSGGOG00000009000 TOP1 ENSMMUG00000011112 TOP1 ENSRNOG00000047611 Top1 ENSBTAG00000007960 TOP1 ENSSSCG00000007355 TOP1 ENSECAG00000000383 TOP1 ENSOCUG00000008221 TOP1 ENSCAFG00000009058 TOP1 ENSFCAG00000009029 TOP1 ENSCPOG00000009076 TOP1 ENSEEUG00000007857 TOP1 ENSOANG00000014354 TOP1 ENSGALG00000003681 TOP1	Compare expression	[+]
Tetrapoda	17 species Homo sapiens (human) Mus musculus (mouse) Pan troglodytes (chimpanzee) Gorilla gorilla (gorilla) Macaca mulatta (macaque) Rattus norvegicus (rat) Bos taurus (cattle) Sus scrofa (pig) Equus caballus (horse) Oryctolagus cuniculus (rabbit) Canis lupus familiaris (dog) Felis catus (cat) Cavia porcellus (guinea pig) Erinaceus europaeus (hedgehog) Ornithorhynchus anatinus (platypus) Gallus gallus (chicken) Xenopus tropicalis (western clawed frog)	17 genes ENSG00000198900 TOP1 ENSMUSG00000070544 Top1 ENSPTRG00000013498 TOP1 ENSGGOG00000009000 TOP1 ENSMMUG00000011112 TOP1 ENSRNOG00000047611 Top1 ENSBTAG00000007960 TOP1 ENSSSCG00000007355 TOP1 ENSECAG00000000383 TOP1 ENSOCUG00000008221 TOP1 ENSCAFG00000009058 TOP1 ENSFCAG00000009029 TOP1 ENSCPOG00000009076 TOP1 ENSEEUG00000007857 TOP1 ENSOANG00000014354 TOP1 ENSGALG00000003681 TOP1 ENSXETG00000013237 top1.2	Compare expression	[+]
Euteleostomi	18 species Homo sapiens (human) Mus musculus (mouse) Danio rerio (zebrafish) Pan troglodytes (chimpanzee) Gorilla gorilla (gorilla) Macaca mulatta (macaque) Rattus norvegicus (rat) Bos taurus (cattle) Sus scrofa (pig) Equus caballus (horse) Oryctolagus cuniculus (rabbit) Canis lupus familiaris (dog) Felis catus (cat) Cavia porcellus (guinea pig) Erinaceus europaeus (hedgehog) Ornithorhynchus anatinus (platypus) Gallus gallus (chicken) Xenopus tropicalis (western clawed frog)	18 genes ENSG00000198900 TOP1 ENSMUSG00000070544 Top1 ENSDARG00000070545 top1l ENSPTRG00000013498 TOP1 ENSGGOG00000009000 TOP1 ENSMMUG00000011112 TOP1 ENSRNOG00000047611 Top1 ENSBTAG00000007960 TOP1 ENSSSCG00000007355 TOP1 ENSECAG00000000383 TOP1 ENSOCUG00000008221 TOP1 ENSCAFG00000009058 TOP1 ENSFCAG00000009029 TOP1 ENSCPOG00000009076 TOP1 ENSEEUG00000007857 TOP1 ENSOANG00000014354 TOP1 ENSGALG00000003681 TOP1 ENSXETG00000013237 top1.2	Compare expression	[+]

Orthology information comes from OMA : ENSACAG00000010889.

Paralogs (same species)

Taxon name	Gene(s)	Expression comparison	See details
Opisthokonta	1 gene ENSACAG00000001329 TOP1MT	Compare expression	[+]

Paralogy information comes from OMA : ENSACAG00000010889.

Cross-references

Ensembl	ENSACAG00000010889 (TOP1)
HGNC	HGNC:11986 (TOP1)
Uniprot/SPTREMBL	H9GH66, H9GH66_ANOCA