B. taurus Gene: TPH1 - ENSBTAG00000005343 - Bos taurus (cattle)

General information

Ensembl IDENSBTAG00000005343
NameTPH1
Descriptiontryptophan hydroxylase 1 [Source:HGNC Symbol;Acc:HGNC:12008]
OrganismBos taurus (cattle)
Synonym(s)sergef, tph, tprh
Orthologs(s)24 orthologs
Paralog(s)3 paralogs

Expression

Anat. entity IDAnatomical entityDevelopmental stage(s)Rank scoreExpression scoreSources
UBERON:0002107liver
  • UBERON:0018241prime adult stage
  • UBERON:0000104life cycle
  • UBERON:0000113post-juvenile adult stage
2.67e3
  • 2.67e3
  • 3.36e3
  • 3.53e3
88.43
  • 88.43
  • 85.44
  • 84.70
AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0002385muscle tissue
  • UBERON:0000104life cycle
6.24e3
  • 6.24e3
72.96
  • 72.96
AEIR
  • AEIR
UBERON:0001134skeletal muscle tissue
  • UBERON:0000104life cycle
7.93e3
  • 7.93e3
65.65
  • 65.65
AEIR
  • AEIR
UBERON:0001013adipose tissue
  • UBERON:0000113post-juvenile adult stage
  • UBERON:0000104life cycle
9.21e3
  • 9.21e3
  • 1.44e4
60.07
  • 60.07
  • 37.80
AEIR
  • AEIR
  • AEIR
UBERON:0001155colon
  • UBERON:0018241prime adult stage
9.81e3
  • 9.81e3
57.48
  • 57.48
AEIR
  • AEIR
UBERON:0001156ascending colon
  • UBERON:0000104life cycle
  • UBERON:0018241prime adult stage
1.15e4
  • 1.15e4
  • 1.15e4
50.14
  • 50.14
  • 50.00
AEIR
  • AEIR
  • AEIR
UBERON:0000966retina
  • UBERON:0000104life cycle
1.16e4
  • 1.16e4
49.88
  • 49.88
AEIR
  • AEIR
UBERON:0015869retropharyngeal lymph node
  • UBERON:0000104life cycle
1.16e4
  • 1.16e4
49.69
  • 49.69
AEIR
  • AEIR
UBERON:0004358caput epididymis
  • UBERON:0018241prime adult stage
1.16e4
  • 1.16e4
49.54
  • 49.54
AEIR
  • AEIR
UBERON:0002507abdominal lymph node
  • UBERON:0018241prime adult stage
1.18e4
  • 1.18e4
48.99
  • 48.99
AEIR
  • AEIR
UBERON:0001911mammary gland
  • UBERON:0000113post-juvenile adult stage
  • UBERON:0018241prime adult stage
  • UBERON:0000104life cycle
1.21e4
  • 1.21e4
  • 1.57e4
  • 1.69e4
47.69
  • 47.69
  • 31.76
  • 26.73
AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0001826nasal cavity mucosa
  • UBERON:0000104life cycle
1.23e4
  • 1.23e4
46.71
  • 46.71
AEIR
  • AEIR
UBERON:0002369adrenal gland
  • UBERON:0000104life cycle
  • UBERON:0018241prime adult stage
1.25e4
  • 1.25e4
  • 1.46e4
45.71
  • 45.71
  • 36.68
AEIR
  • AEIR
  • AEIR
UBERON:0002081cardiac atrium
  • UBERON:0018241prime adult stage
  • UBERON:0000104life cycle
1.28e4
  • 1.28e4
  • 1.28e4
44.65
  • 44.65
  • 44.61
AEIR
  • AEIR
  • AEIR
UBERON:0000178blood
  • UBERON:0018241prime adult stage
1.29e4
  • 1.29e4
44.23
  • 44.23
AEIR
  • AEIR
UBERON:0002106spleen
  • UBERON:0018241prime adult stage
  • UBERON:0000104life cycle
1.30e4
  • 1.30e4
  • 1.52e4
43.50
  • 43.50
  • 34.03
AEIR
  • AEIR
  • AEIR
UBERON:0002509mesenteric lymph node
  • UBERON:0018241prime adult stage
1.31e4
  • 1.31e4
43.26
  • 43.26
AEIR
  • AEIR
UBERON:0002196adenohypophysis
  • UBERON:0000104life cycle
1.32e4
  • 1.32e4
42.92
  • 42.92
AEIR
  • AEIR
UBERON:0001295endometrium
  • UBERON:0000104life cycle
  • UBERON:0000113post-juvenile adult stage
1.33e4
  • 1.33e4
  • 1.79e4
42.34
  • 42.34
  • 22.62
AEIR
  • AEIR
  • AEIR
UBERON:0000007pituitary gland
  • UBERON:0018241prime adult stage
1.39e4
  • 1.39e4
39.87
  • 39.87
AEIR
  • AEIR
UBERON:0001723tongue
  • UBERON:0018241prime adult stage
1.39e4
  • 1.39e4
39.72
  • 39.72
AEIR
  • AEIR
UBERON:0002037cerebellum
  • UBERON:0018241prime adult stage
  • UBERON:0000104life cycle
1.39e4
  • 1.39e4
  • 2.01e4
39.72
  • 39.72
  • 13.10
AEIR
  • AEIR
  • AEIR
UBERON:0000378tongue muscle
  • UBERON:0000104life cycle
1.42e4
  • 1.42e4
38.49
  • 38.49
AEIR
  • AEIR
UBERON:0016632isthmus of fallopian tube
  • UBERON:0000104life cycle
1.43e4
  • 1.43e4
38.23
  • 38.23
AEIR
  • AEIR
UBERON:0001255urinary bladder
  • UBERON:0000104life cycle
1.44e4
  • 1.44e4
37.73
  • 37.73
AEIR
  • AEIR
UBERON:0002190subcutaneous adipose tissue
  • UBERON:0000104life cycle
  • UBERON:0000112sexually immature stage
  • UBERON:0018241prime adult stage
1.44e4
  • 1.44e4
  • 1.68e4
  • 1.68e4
37.71
  • 37.71
  • 27.08
  • 26.99
AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0001401longissimus thoracis muscle
  • UBERON:0000104life cycle
1.44e4
  • 1.44e4
37.69
  • 37.69
AEIR
  • AEIR
UBERON:0003984uterine tube infundibulum
  • UBERON:0000104life cycle
1.45e4
  • 1.45e4
37.22
  • 37.22
AEIR
  • AEIR
UBERON:0002046thyroid gland
  • UBERON:0018241prime adult stage
1.46e4
  • 1.46e4
36.76
  • 36.76
AEIR
  • AEIR
UBERON:0001153caecum
  • UBERON:0000104life cycle
1.46e4
  • 1.46e4
36.63
  • 36.63
AEIR
  • AEIR
UBERON:0002198neurohypophysis
  • UBERON:0000104life cycle
1.46e4
  • 1.46e4
36.57
  • 36.57
AEIR
  • AEIR
UBERON:0000057urethra
  • UBERON:0000104life cycle
1.47e4
  • 1.47e4
36.15
  • 36.15
AEIR
  • AEIR
UBERON:0000992female gonad
  • UBERON:0018241prime adult stage
1.48e4
  • 1.48e4
35.78
  • 35.78
AEIR
  • AEIR
UBERON:0002021occipital lobe
  • UBERON:0018241prime adult stage
1.49e4
  • 1.49e4
35.28
  • 35.28
AEIR
  • AEIR
UBERON:0004180mammary gland fat
  • UBERON:0018241prime adult stage
1.49e4
  • 1.49e4
35.25
  • 35.25
AEIR
  • AEIR
UBERON:0002110gall bladder
  • UBERON:0000104life cycle
1.49e4
  • 1.49e4
35.23
  • 35.23
AEIR
  • AEIR
UBERON:0007365rumen
  • UBERON:0000112sexually immature stage
1.53e4
  • 1.53e4
33.89
  • 33.89
AEIR
  • AEIR
UBERON:0000956cerebral cortex
  • UBERON:0000104life cycle
1.53e4
  • 1.53e4
33.68
  • 33.68
AEIR
  • AEIR
UBERON:0002116ileum
  • UBERON:0000104life cycle
  • UBERON:0018241prime adult stage
1.54e4
  • 1.54e4
  • 1.57e4
33.46
  • 33.46
  • 32.11
AEIR
  • AEIR
  • AEIR
UBERON:0012648ampulla of uterine tube
  • UBERON:0000104life cycle
1.57e4
  • 1.57e4
32.17
  • 32.17
AEIR
  • AEIR
UBERON:0002114duodenum
  • UBERON:0000104life cycle
1.57e4
  • 1.57e4
31.96
  • 31.96
AEIR
  • AEIR
UBERON:0002247uterine horn
  • UBERON:0018241prime adult stage
1.59e4
  • 1.59e4
31.27
  • 31.27
AEIR
  • AEIR
UBERON:0000451prefrontal cortex
  • UBERON:0018241prime adult stage
1.61e4
  • 1.61e4
30.08
  • 30.08
AEIR
  • AEIR
UBERON:0002113kidney
  • UBERON:0000104life cycle
1.62e4
  • 1.62e4
29.63
  • 29.63
AEIR
  • AEIR
UBERON:0005386olfactory segment of nasal mucosa
  • UBERON:0000104life cycle
1.63e4
  • 1.63e4
29.15
  • 29.15
AEIR
  • AEIR
UBERON:0002115jejunum
  • UBERON:0000104life cycle
1.65e4
  • 1.65e4
28.53
  • 28.53
AEIR
  • AEIR
UBERON:0001375semitendinosus
  • UBERON:0000104life cycle
  • UBERON:0000113post-juvenile adult stage
1.66e4
  • 1.66e4
  • 1.78e4
28.17
  • 28.17
  • 22.68
AEIR
  • AEIR
  • AEIR
UBERON:0002048lung
  • UBERON:0018241prime adult stage
  • UBERON:0000104life cycle
1.67e4
  • 1.67e4
  • 1.78e4
27.84
  • 27.84
  • 22.99
AEIR
  • AEIR
  • AEIR
UBERON:0000082adult mammalian kidney
  • UBERON:0018241prime adult stage
1.73e4
  • 1.73e4
24.83
  • 24.83
AEIR
  • AEIR
UBERON:0001913milk
  • UBERON:0000113post-juvenile adult stage
1.74e4
  • 1.74e4
24.55
  • 24.55
AEIR
  • AEIR
CL:0000503theca cell
  • UBERON:0018241prime adult stage
1.85e4
  • 1.85e4
19.94
  • 19.94
AEIR
  • AEIR
Sources
AAffymetrix
EEST
IIn Situ
RRNA-Seq
data
no data
Rank scores
3.25e4lightgrey: low confidence scores

important score variation

Rank scores of expression calls are normalized across genes, conditions and species. Low score means that the gene is highly expressed in the condition. Max rank score in all species: 4.10e4. Min rank score varies across species.

Expression scores of expression calls use the minimum and maximum Rank of the species to normalize the expression to a value between 0 and 100. Low score means that the gene is lowly expressed in the condition.

Sources of annotations to anatomy and development:
  • RNA-Seq data: Bgee
Sources of raw data:
  • RNA-Seq data: GEO

Orthologs

Taxon nameSpecies with orthologsGene(s)Expression comparisonSee details
Laurasiatheria4 species4 genesCompare expression
Boreoeutheria12 species12 genesCompare expression
Theria13 species13 genesCompare expression
Mammalia14 species14 genesCompare expression
Amniota16 species16 genesCompare expression
Tetrapoda17 species17 genesCompare expression
Euteleostomi18 species18 genesCompare expression
Bilateria24 species24 genesCompare expression

Orthology information comes from OMA : ENSBTAG00000005343.

Paralogs (same species)

Taxon nameGene(s)Expression comparisonSee details
Chordata1 geneCompare expression
Eukaryota3 genesCompare expression

Paralogy information comes from OMA : ENSBTAG00000005343.

Cross-references

EnsemblENSBTAG00000005343 (TPH1)
HGNCHGNC:12008 (TPH1)
EMBLDAAA02040572, DAAA02040573
Uniprot/SPTREMBLF1N5Q8, F1N5Q8_BOVIN

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