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B. taurus Gene: EIF2AK4 - ENSBTAG00000014351 - Bos taurus (cattle)

General information

Ensembl IDENSBTAG00000014351
NameEIF2AK4
Descriptioneukaryotic translation initiation factor 2 alpha kinase 4 [Source:HGNC Symbol;Acc:HGNC:19687]
OrganismBos taurus (cattle)
Synonym(s)gcn2, gcn2-like, kiaa1338
Orthologs(s)23 orthologs

Expression

Anat. entity IDAnatomical entityDevelopmental stage(s)Rank scoreExpression scoreSources
UBERON:0000473testis
  • UBERON:0000112sexually immature stage
  • UBERON:0018241prime adult stage
  • UBERON:0000113post-juvenile adult stage
  • UBERON:0000104life cycle
3.91e3
  • 3.91e3
  • 7.91e3
  • 8.11e3
  • 1.37e4
83.04
  • 83.04
  • 65.72
  • 64.86
  • 40.61
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0001911mammary gland
  • UBERON:0018241prime adult stage
  • UBERON:0000104life cycle
  • UBERON:0000113post-juvenile adult stage
4.41e3
  • 4.41e3
  • 7.92e3
  • 1.21e4
80.90
  • 80.90
  • 65.68
  • 47.69
AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0001296myometrium
  • UBERON:0000104life cycle
4.83e3
  • 4.83e3
79.09
  • 79.09
AEIR
  • AEIR
UBERON:0000992female gonad
  • UBERON:0018241prime adult stage
5.14e3
  • 5.14e3
77.72
  • 77.72
AEIR
  • AEIR
UBERON:0007358abomasum
  • UBERON:0000104life cycle
  • UBERON:0018241prime adult stage
5.21e3
  • 5.21e3
  • 5.22e3
77.44
  • 77.44
  • 77.36
AEIR
  • AEIR
  • AEIR
UBERON:0002247uterine horn
  • UBERON:0018241prime adult stage
5.22e3
  • 5.22e3
77.40
  • 77.40
AEIR
  • AEIR
CL:0000501granulosa cell
  • UBERON:0018241prime adult stage
5.25e3
  • 5.25e3
77.23
  • 77.23
AEIR
  • AEIR
UBERON:0001044saliva-secreting gland
  • UBERON:0000104life cycle
5.28e3
  • 5.28e3
77.14
  • 77.14
AEIR
  • AEIR
UBERON:0001295endometrium
  • UBERON:0000113post-juvenile adult stage
  • UBERON:0000104life cycle
5.29e3
  • 5.29e3
  • 6.78e3
77.06
  • 77.06
  • 70.63
AEIR
  • AEIR
  • AEIR
UBERON:0001987placenta
  • UBERON:0000113post-juvenile adult stage
  • UBERON:0018241prime adult stage
5.31e3
  • 5.31e3
  • 8.95e3
76.98
  • 76.98
  • 61.22
AEIR
  • AEIR
  • AEIR
UBERON:0002190subcutaneous adipose tissue
  • UBERON:0000068embryo stage
  • UBERON:0018241prime adult stage
  • UBERON:0000112sexually immature stage
  • UBERON:0000104life cycle
5.33e3
  • 5.33e3
  • 7.17e3
  • 7.23e3
  • 8.33e3
76.92
  • 76.92
  • 68.92
  • 68.65
  • 63.90
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0002116ileum
  • UBERON:0000104life cycle
  • UBERON:0018241prime adult stage
5.44e3
  • 5.44e3
  • 7.19e3
76.44
  • 76.44
  • 68.84
AEIR
  • AEIR
  • AEIR
CL:0000018spermatid
  • UBERON:0018241prime adult stage
5.48e3
  • 5.48e3
76.23
  • 76.23
AEIR
  • AEIR
UBERON:0002369adrenal gland
  • UBERON:0018241prime adult stage
  • UBERON:0000104life cycle
5.53e3
  • 5.53e3
  • 7.79e3
76.05
  • 76.05
  • 66.24
AEIR
  • AEIR
  • AEIR
UBERON:0005386olfactory segment of nasal mucosa
  • UBERON:0000104life cycle
5.69e3
  • 5.69e3
75.32
  • 75.32
AEIR
  • AEIR
CL:0000017spermatocyte
  • UBERON:0018241prime adult stage
5.72e3
  • 5.72e3
75.22
  • 75.22
AEIR
  • AEIR
UBERON:0001103diaphragm
  • UBERON:0000104life cycle
5.75e3
  • 5.75e3
75.08
  • 75.08
AEIR
  • AEIR
UBERON:0002110gall bladder
  • UBERON:0000104life cycle
5.77e3
  • 5.77e3
74.99
  • 74.99
AEIR
  • AEIR
CL:0000738leukocyte
  • UBERON:0000112sexually immature stage
  • UBERON:0000104life cycle
  • UBERON:0018241prime adult stage
5.89e3
  • 5.89e3
  • 6.81e3
  • 7.52e3
74.45
  • 74.45
  • 70.50
  • 67.41
AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0002037cerebellum
  • UBERON:0018241prime adult stage
  • UBERON:0000104life cycle
5.92e3
  • 5.92e3
  • 9.03e3
74.37
  • 74.37
  • 60.86
AEIR
  • AEIR
  • AEIR
UBERON:0000178blood
  • UBERON:0018241prime adult stage
6.01e3
  • 6.01e3
73.97
  • 73.97
AEIR
  • AEIR
UBERON:0002507abdominal lymph node
  • UBERON:0018241prime adult stage
6.01e3
  • 6.01e3
73.94
  • 73.94
AEIR
  • AEIR
UBERON:0002385muscle tissue
  • UBERON:0000104life cycle
  • UBERON:0018241prime adult stage
6.02e3
  • 6.02e3
  • 6.78e3
73.92
  • 73.92
  • 70.63
AEIR
  • AEIR
  • AEIR
UBERON:0002048lung
  • UBERON:0018241prime adult stage
  • UBERON:0000104life cycle
6.14e3
  • 6.14e3
  • 6.44e3
73.38
  • 73.38
  • 72.08
AEIR
  • AEIR
  • AEIR
UBERON:0007365rumen
  • UBERON:0000112sexually immature stage
6.15e3
  • 6.15e3
73.35
  • 73.35
AEIR
  • AEIR
UBERON:0001255urinary bladder
  • UBERON:0000104life cycle
6.15e3
  • 6.15e3
73.34
  • 73.34
AEIR
  • AEIR
UBERON:0002106spleen
  • UBERON:0018241prime adult stage
  • UBERON:0000104life cycle
6.18e3
  • 6.18e3
  • 6.90e3
73.20
  • 73.20
  • 70.09
AEIR
  • AEIR
  • AEIR
UBERON:0001401longissimus thoracis muscle
  • UBERON:0000104life cycle
  • UBERON:0018241prime adult stage
6.24e3
  • 6.24e3
  • 8.59e3
72.97
  • 72.97
  • 62.77
AEIR
  • AEIR
  • AEIR
UBERON:0002509mesenteric lymph node
  • UBERON:0018241prime adult stage
6.27e3
  • 6.27e3
72.84
  • 72.84
AEIR
  • AEIR
CL:0000503theca cell
  • UBERON:0018241prime adult stage
6.29e3
  • 6.29e3
72.75
  • 72.75
AEIR
  • AEIR
UBERON:0015869retropharyngeal lymph node
  • UBERON:0000104life cycle
6.30e3
  • 6.30e3
72.68
  • 72.68
AEIR
  • AEIR
UBERON:0000014zone of skin
  • UBERON:0018241prime adult stage
6.34e3
  • 6.34e3
72.52
  • 72.52
AEIR
  • AEIR
UBERON:0001898hypothalamus
  • UBERON:0000104life cycle
6.39e3
  • 6.39e3
72.32
  • 72.32
AEIR
  • AEIR
UBERON:0004358caput epididymis
  • UBERON:0018241prime adult stage
6.39e3
  • 6.39e3
72.29
  • 72.29
AEIR
  • AEIR
UBERON:0002046thyroid gland
  • UBERON:0018241prime adult stage
6.40e3
  • 6.40e3
72.27
  • 72.27
AEIR
  • AEIR
UBERON:0000947aorta
  • UBERON:0000104life cycle
6.49e3
  • 6.49e3
71.89
  • 71.89
AEIR
  • AEIR
UBERON:0008285rumen epithelium
  • UBERON:0018241prime adult stage
6.53e3
  • 6.53e3
71.70
  • 71.70
AEIR
  • AEIR
UBERON:0010153rumen papilla
  • UBERON:0000104life cycle
  • UBERON:0018241prime adult stage
6.55e3
  • 6.55e3
  • 6.58e3
71.60
  • 71.60
  • 71.47
AEIR
  • AEIR
  • AEIR
UBERON:0003126trachea
  • UBERON:0000104life cycle
6.56e3
  • 6.56e3
71.56
  • 71.56
AEIR
  • AEIR
UBERON:0002021occipital lobe
  • UBERON:0018241prime adult stage
6.63e3
  • 6.63e3
71.29
  • 71.29
AEIR
  • AEIR
UBERON:0016632isthmus of fallopian tube
  • UBERON:0000104life cycle
6.76e3
  • 6.76e3
70.71
  • 70.71
AEIR
  • AEIR
UBERON:0001156ascending colon
  • UBERON:0000104life cycle
  • UBERON:0018241prime adult stage
6.82e3
  • 6.82e3
  • 6.83e3
70.44
  • 70.44
  • 70.41
AEIR
  • AEIR
  • AEIR
UBERON:0001158descending colon
  • UBERON:0000104life cycle
6.83e3
  • 6.83e3
70.41
  • 70.41
AEIR
  • AEIR
UBERON:0002107liver
  • UBERON:0018241prime adult stage
  • UBERON:0000104life cycle
  • UBERON:0000113post-juvenile adult stage
6.84e3
  • 6.84e3
  • 6.99e3
  • 7.67e3
70.35
  • 70.35
  • 69.72
  • 66.75
AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0001913milk
  • UBERON:0000113post-juvenile adult stage
6.86e3
  • 6.86e3
70.28
  • 70.28
AEIR
  • AEIR
UBERON:0007625pigment epithelium of eye
  • UBERON:0000104life cycle
6.97e3
  • 6.97e3
69.78
  • 69.78
AEIR
  • AEIR
CL:0000711cumulus cell
  • UBERON:0000104life cycle
6.99e3
  • 6.99e3
69.72
  • 69.72
AEIR
  • AEIR
UBERON:0001111intercostal muscle
  • UBERON:0000104life cycle
7.10e3
  • 7.10e3
69.22
  • 69.22
AEIR
  • AEIR
UBERON:0002367prostate gland
  • UBERON:0018241prime adult stage
7.11e3
  • 7.11e3
69.19
  • 69.19
AEIR
  • AEIR
UBERON:0000002uterine cervix
  • UBERON:0018241prime adult stage
  • UBERON:0000104life cycle
7.13e3
  • 7.13e3
  • 7.14e3
69.12
  • 69.12
  • 69.08
AEIR
  • AEIR
  • AEIR
CL:0000775neutrophil
  • UBERON:0018241prime adult stage
7.14e3
  • 7.14e3
69.04
  • 69.04
AEIR
  • AEIR
UBERON:0012648ampulla of uterine tube
  • UBERON:0000104life cycle
7.26e3
  • 7.26e3
68.56
  • 68.56
AEIR
  • AEIR
UBERON:0001378rectus femoris
  • UBERON:0000104life cycle
7.28e3
  • 7.28e3
68.44
  • 68.44
AEIR
  • AEIR
UBERON:0004703dorsal thalamus
  • UBERON:0018241prime adult stage
7.30e3
  • 7.30e3
68.37
  • 68.37
AEIR
  • AEIR
UBERON:0000051fornix of vagina
  • UBERON:0000104life cycle
7.30e3
  • 7.30e3
68.36
  • 68.36
AEIR
  • AEIR
UBERON:0001723tongue
  • UBERON:0018241prime adult stage
7.31e3
  • 7.31e3
68.33
  • 68.33
AEIR
  • AEIR
UBERON:0000451prefrontal cortex
  • UBERON:0018241prime adult stage
7.33e3
  • 7.33e3
68.24
  • 68.24
AEIR
  • AEIR
UBERON:0002115jejunum
  • UBERON:0000104life cycle
  • UBERON:0018241prime adult stage
7.41e3
  • 7.41e3
  • 7.97e3
67.87
  • 67.87
  • 65.47
AEIR
  • AEIR
  • AEIR
UBERON:0002114duodenum
  • UBERON:0000104life cycle
7.42e3
  • 7.42e3
67.84
  • 67.84
AEIR
  • AEIR
UBERON:0000007pituitary gland
  • UBERON:0018241prime adult stage
7.45e3
  • 7.45e3
67.72
  • 67.72
AEIR
  • AEIR
UBERON:0001381semimembranosus muscle
  • UBERON:0018241prime adult stage
  • UBERON:0000104life cycle
7.49e3
  • 7.49e3
  • 8.40e3
67.54
  • 67.54
  • 63.61
AEIR
  • AEIR
  • AEIR
UBERON:0001375semitendinosus
  • UBERON:0000104life cycle
  • UBERON:0000113post-juvenile adult stage
  • UBERON:0018241prime adult stage
7.50e3
  • 7.50e3
  • 8.06e3
  • 8.46e3
67.51
  • 67.51
  • 65.08
  • 63.32
AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0002000gluteal muscle
  • UBERON:0000104life cycle
7.51e3
  • 7.51e3
67.45
  • 67.45
AEIR
  • AEIR
UBERON:0004716conceptus
  • UBERON:0000068embryo stage
7.52e3
  • 7.52e3
67.41
  • 67.41
AEIR
  • AEIR
UBERON:0007361ruminant reticulum
  • UBERON:0018241prime adult stage
7.55e3
  • 7.55e3
67.27
  • 67.27
AEIR
  • AEIR
UBERON:0007362omasum
  • UBERON:0018241prime adult stage
  • UBERON:0000104life cycle
7.55e3
  • 7.55e3
  • 7.62e3
67.26
  • 67.26
  • 67.00
AEIR
  • AEIR
  • AEIR
UBERON:0001371gluteus medius
  • UBERON:0000104life cycle
7.56e3
  • 7.56e3
67.25
  • 67.25
AEIR
  • AEIR
UBERON:0000057urethra
  • UBERON:0000104life cycle
7.58e3
  • 7.58e3
67.14
  • 67.14
AEIR
  • AEIR
UBERON:0000082adult mammalian kidney
  • UBERON:0018241prime adult stage
7.61e3
  • 7.61e3
67.02
  • 67.02
AEIR
  • AEIR
UBERON:0001509triceps brachii
  • UBERON:0018241prime adult stage
  • UBERON:0000104life cycle
7.64e3
  • 7.64e3
  • 7.65e3
66.90
  • 66.90
  • 66.87
AEIR
  • AEIR
  • AEIR
UBERON:0001153caecum
  • UBERON:0000104life cycle
7.67e3
  • 7.67e3
66.75
  • 66.75
AEIR
  • AEIR
UBERON:0002196adenohypophysis
  • UBERON:0000104life cycle
7.71e3
  • 7.71e3
66.60
  • 66.60
AEIR
  • AEIR
UBERON:0000948heart
  • UBERON:0000104life cycle
  • UBERON:0018241prime adult stage
7.71e3
  • 7.71e3
  • 8.61e3
66.56
  • 66.56
  • 62.67
AEIR
  • AEIR
  • AEIR
UBERON:0004180mammary gland fat
  • UBERON:0018241prime adult stage
7.81e3
  • 7.81e3
66.13
  • 66.13
AEIR
  • AEIR
UBERON:0002383supraspinatus muscle
  • UBERON:0000104life cycle
  • UBERON:0018241prime adult stage
7.84e3
  • 7.84e3
  • 7.84e3
66.04
  • 66.04
  • 66.02
AEIR
  • AEIR
  • AEIR
UBERON:0001134skeletal muscle tissue
  • UBERON:0000104life cycle
  • UBERON:0018241prime adult stage
7.86e3
  • 7.86e3
  • 8.05e3
65.92
  • 65.92
  • 65.11
AEIR
  • AEIR
  • AEIR
UBERON:0000378tongue muscle
  • UBERON:0000104life cycle
7.97e3
  • 7.97e3
65.45
  • 65.45
AEIR
  • AEIR
UBERON:0000966retina
  • UBERON:0000104life cycle
8.01e3
  • 8.01e3
65.28
  • 65.28
AEIR
  • AEIR
UBERON:0000362renal medulla
  • UBERON:0000104life cycle
8.03e3
  • 8.03e3
65.19
  • 65.19
AEIR
  • AEIR
UBERON:0001043esophagus
  • UBERON:0000104life cycle
8.08e3
  • 8.08e3
64.97
  • 64.97
AEIR
  • AEIR
UBERON:0001225cortex of kidney
  • UBERON:0000104life cycle
8.09e3
  • 8.09e3
64.93
  • 64.93
AEIR
  • AEIR
UBERON:0002198neurohypophysis
  • UBERON:0000104life cycle
8.10e3
  • 8.10e3
64.92
  • 64.92
AEIR
  • AEIR
UBERON:0000988pons
  • UBERON:0000104life cycle
8.39e3
  • 8.39e3
63.63
  • 63.63
AEIR
  • AEIR
UBERON:0000056ureter
  • UBERON:0000104life cycle
8.39e3
  • 8.39e3
63.63
  • 63.63
AEIR
  • AEIR
UBERON:0002081cardiac atrium
  • UBERON:0018241prime adult stage
  • UBERON:0000104life cycle
8.41e3
  • 8.41e3
  • 8.43e3
63.56
  • 63.56
  • 63.46
AEIR
  • AEIR
  • AEIR
UBERON:0003984uterine tube infundibulum
  • UBERON:0000104life cycle
8.54e3
  • 8.54e3
63.00
  • 63.00
AEIR
  • AEIR
UBERON:0002371bone marrow
  • UBERON:0018241prime adult stage
8.54e3
  • 8.54e3
62.98
  • 62.98
AEIR
  • AEIR
UBERON:0001477infraspinatus muscle
  • UBERON:0018241prime adult stage
  • UBERON:0000104life cycle
8.84e3
  • 8.84e3
  • 8.85e3
61.71
  • 61.71
  • 61.65
AEIR
  • AEIR
  • AEIR
UBERON:0002512corpus luteum
  • UBERON:0000104life cycle
8.90e3
  • 8.90e3
61.41
  • 61.41
AEIR
  • AEIR
UBERON:0001000vas deferens
  • UBERON:0018241prime adult stage
8.96e3
  • 8.96e3
61.16
  • 61.16
AEIR
  • AEIR
UBERON:0001954Ammon's horn
  • UBERON:0000068embryo stage
9.26e3
  • 9.26e3
59.88
  • 59.88
AEIR
  • AEIR
UBERON:0001739laryngeal cartilage
  • UBERON:0000104life cycle
9.26e3
  • 9.26e3
59.88
  • 59.88
AEIR
  • AEIR
UBERON:0016538temporal cortex
  • UBERON:0000104life cycle
9.35e3
  • 9.35e3
59.47
  • 59.47
AEIR
  • AEIR
UBERON:0007367surface of tongue
  • UBERON:0000104life cycle
9.42e3
  • 9.42e3
59.17
  • 59.17
AEIR
  • AEIR
UBERON:0003309floor plate of diencephalon
  • UBERON:0018241prime adult stage
9.56e3
  • 9.56e3
58.58
  • 58.58
AEIR
  • AEIR
UBERON:0001374biceps femoris
  • UBERON:0000104life cycle
9.64e3
  • 9.64e3
58.24
  • 58.24
AEIR
  • AEIR
UBERON:0001886choroid plexus
  • UBERON:0018241prime adult stage
9.68e3
  • 9.68e3
58.03
  • 58.03
AEIR
  • AEIR
Sources
AAffymetrix
EEST
IIn Situ
RRNA-Seq
data
no data
Rank scores
3.25e4lightgrey: low confidence scores

important score variation

Rank scores of expression calls are normalized across genes, conditions and species. Low score means that the gene is highly expressed in the condition. Max rank score in all species: 4.10e4. Min rank score varies across species.

Expression scores of expression calls use the minimum and maximum Rank of the species to normalize the expression to a value between 0 and 100. Low score means that the gene is lowly expressed in the condition.

Sources of annotations to anatomy and development:
  • RNA-Seq data: Bgee
Sources of raw data:
  • RNA-Seq data: GEO

Orthologs

Taxon nameSpecies with orthologsGene(s)Expression comparisonSee details
Laurasiatheria4 species4 genesCompare expression
Boreoeutheria11 species11 genesCompare expression
Mammalia12 species12 genesCompare expression
Amniota14 species14 genesCompare expression
Tetrapoda15 species15 genesCompare expression
Euteleostomi16 species16 genesCompare expression
Bilateria23 species23 genesCompare expression

Orthology information comes from OMA : ENSBTAG00000014351.

Cross-references

EnsemblENSBTAG00000014351 (EIF2AK4)
HGNCHGNC:19687 (EIF2AK4)
EMBLDAAA02028541
Uniprot/SPTREMBLE1BAL6, E1BAL6_BOVIN

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