B. taurus Gene: HMGCL - ENSBTAG00000021832 - Bos taurus (cattle)

General information

Ensembl IDENSBTAG00000021832
NameHMGCL
Description3-hydroxymethyl-3-methylglutaryl-CoA lyase [Source:HGNC Symbol;Acc:HGNC:5005]
OrganismBos taurus (cattle)
Synonym(s)hl, q148j2
Orthologs(s)25 orthologs
Paralog(s)1 paralogs

Expression

Anat. entity IDAnatomical entityDevelopmental stage(s)Rank scoreExpression scoreSources
UBERON:0010153rumen papilla
  • UBERON:0018241prime adult stage
  • UBERON:0000104life cycle
230
  • 230
  • 234
99.01
  • 99.01
  • 98.99
AEIR
  • AEIR
  • AEIR
UBERON:0007361ruminant reticulum
  • UBERON:0018241prime adult stage
255
  • 255
98.90
  • 98.90
AEIR
  • AEIR
UBERON:0007362omasum
  • UBERON:0000104life cycle
  • UBERON:0018241prime adult stage
353
  • 353
  • 360
98.47
  • 98.47
  • 98.44
AEIR
  • AEIR
  • AEIR
UBERON:0001043esophagus
  • UBERON:0000104life cycle
605
  • 605
97.38
  • 97.38
AEIR
  • AEIR
UBERON:0007365rumen
  • UBERON:0000112sexually immature stage
654
  • 654
97.17
  • 97.17
AEIR
  • AEIR
UBERON:0002107liver
  • UBERON:0000113post-juvenile adult stage
  • UBERON:0018241prime adult stage
  • UBERON:0000104life cycle
1.09e3
  • 1.09e3
  • 1.46e3
  • 1.68e3
95.26
  • 95.26
  • 93.68
  • 92.73
AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0007367surface of tongue
  • UBERON:0000104life cycle
1.25e3
  • 1.25e3
94.57
  • 94.57
AEIR
  • AEIR
UBERON:0001013adipose tissue
  • UBERON:0000113post-juvenile adult stage
  • UBERON:0000104life cycle
1.87e3
  • 1.87e3
  • 2.18e3
91.92
  • 91.92
  • 90.55
AEIR
  • AEIR
  • AEIR
UBERON:0007358abomasum
  • UBERON:0018241prime adult stage
  • UBERON:0000104life cycle
1.87e3
  • 1.87e3
  • 1.88e3
91.90
  • 91.90
  • 91.86
AEIR
  • AEIR
  • AEIR
UBERON:0002371bone marrow
  • UBERON:0018241prime adult stage
2.29e3
  • 2.29e3
90.09
  • 90.09
AEIR
  • AEIR
UBERON:0000057urethra
  • UBERON:0000104life cycle
2.46e3
  • 2.46e3
89.36
  • 89.36
AEIR
  • AEIR
UBERON:0002190subcutaneous adipose tissue
  • UBERON:0000104life cycle
  • UBERON:0018241prime adult stage
  • UBERON:0000112sexually immature stage
  • UBERON:0000068embryo stage
2.48e3
  • 2.48e3
  • 2.53e3
  • 2.61e3
  • 5.28e3
89.27
  • 89.27
  • 89.02
  • 88.69
  • 77.13
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0001225cortex of kidney
  • UBERON:0000104life cycle
2.48e3
  • 2.48e3
89.25
  • 89.25
AEIR
  • AEIR
UBERON:0002115jejunum
  • UBERON:0018241prime adult stage
  • UBERON:0000104life cycle
2.59e3
  • 2.59e3
  • 3.12e3
88.77
  • 88.77
  • 86.47
AEIR
  • AEIR
  • AEIR
UBERON:0016632isthmus of fallopian tube
  • UBERON:0000104life cycle
2.69e3
  • 2.69e3
88.33
  • 88.33
AEIR
  • AEIR
UBERON:0001826nasal cavity mucosa
  • UBERON:0000104life cycle
2.86e3
  • 2.86e3
87.63
  • 87.63
AEIR
  • AEIR
UBERON:0001255urinary bladder
  • UBERON:0000104life cycle
2.88e3
  • 2.88e3
87.54
  • 87.54
AEIR
  • AEIR
UBERON:0000988pons
  • UBERON:0000104life cycle
2.92e3
  • 2.92e3
87.35
  • 87.35
AEIR
  • AEIR
UBERON:0002512corpus luteum
  • UBERON:0000104life cycle
2.97e3
  • 2.97e3
87.12
  • 87.12
AEIR
  • AEIR
UBERON:0000378tongue muscle
  • UBERON:0000104life cycle
2.99e3
  • 2.99e3
87.07
  • 87.07
AEIR
  • AEIR
UBERON:0000002uterine cervix
  • UBERON:0000104life cycle
  • UBERON:0018241prime adult stage
3.04e3
  • 3.04e3
  • 3.05e3
86.83
  • 86.83
  • 86.78
AEIR
  • AEIR
  • AEIR
UBERON:0000966retina
  • UBERON:0000104life cycle
3.10e3
  • 3.10e3
86.56
  • 86.56
AEIR
  • AEIR
UBERON:0000947aorta
  • UBERON:0000104life cycle
3.13e3
  • 3.13e3
86.45
  • 86.45
AEIR
  • AEIR
UBERON:0001886choroid plexus
  • UBERON:0018241prime adult stage
3.20e3
  • 3.20e3
86.15
  • 86.15
AEIR
  • AEIR
UBERON:0002048lung
  • UBERON:0000104life cycle
  • UBERON:0018241prime adult stage
3.21e3
  • 3.21e3
  • 4.44e3
86.08
  • 86.08
  • 80.78
AEIR
  • AEIR
  • AEIR
UBERON:0004180mammary gland fat
  • UBERON:0018241prime adult stage
3.22e3
  • 3.22e3
86.04
  • 86.04
AEIR
  • AEIR
UBERON:0001153caecum
  • UBERON:0000104life cycle
3.26e3
  • 3.26e3
85.89
  • 85.89
AEIR
  • AEIR
UBERON:0001158descending colon
  • UBERON:0000104life cycle
3.30e3
  • 3.30e3
85.70
  • 85.70
AEIR
  • AEIR
UBERON:0001000vas deferens
  • UBERON:0018241prime adult stage
3.31e3
  • 3.31e3
85.68
  • 85.68
AEIR
  • AEIR
UBERON:0000051fornix of vagina
  • UBERON:0000104life cycle
3.34e3
  • 3.34e3
85.54
  • 85.54
AEIR
  • AEIR
UBERON:0001156ascending colon
  • UBERON:0018241prime adult stage
  • UBERON:0000104life cycle
3.38e3
  • 3.38e3
  • 3.39e3
85.36
  • 85.36
  • 85.31
AEIR
  • AEIR
  • AEIR
UBERON:0000082adult mammalian kidney
  • UBERON:0018241prime adult stage
3.40e3
  • 3.40e3
85.28
  • 85.28
AEIR
  • AEIR
UBERON:0001739laryngeal cartilage
  • UBERON:0000104life cycle
3.40e3
  • 3.40e3
85.25
  • 85.25
AEIR
  • AEIR
UBERON:0000014zone of skin
  • UBERON:0018241prime adult stage
3.49e3
  • 3.49e3
84.88
  • 84.88
AEIR
  • AEIR
UBERON:0002385muscle tissue
  • UBERON:0000104life cycle
  • UBERON:0018241prime adult stage
3.60e3
  • 3.60e3
  • 8.03e3
84.40
  • 84.40
  • 65.19
AEIR
  • AEIR
  • AEIR
UBERON:0002509mesenteric lymph node
  • UBERON:0018241prime adult stage
3.63e3
  • 3.63e3
84.25
  • 84.25
AEIR
  • AEIR
UBERON:0002369adrenal gland
  • UBERON:0000104life cycle
  • UBERON:0018241prime adult stage
3.65e3
  • 3.65e3
  • 4.25e3
84.20
  • 84.20
  • 81.60
AEIR
  • AEIR
  • AEIR
UBERON:0001295endometrium
  • UBERON:0000104life cycle
  • UBERON:0000113post-juvenile adult stage
3.65e3
  • 3.65e3
  • 3.94e3
84.18
  • 84.18
  • 82.95
AEIR
  • AEIR
  • AEIR
UBERON:0002367prostate gland
  • UBERON:0018241prime adult stage
3.69e3
  • 3.69e3
84.00
  • 84.00
AEIR
  • AEIR
UBERON:0002196adenohypophysis
  • UBERON:0000104life cycle
3.74e3
  • 3.74e3
83.79
  • 83.79
AEIR
  • AEIR
UBERON:0001374biceps femoris
  • UBERON:0000104life cycle
3.79e3
  • 3.79e3
83.58
  • 83.58
AEIR
  • AEIR
CL:0000738leukocyte
  • UBERON:0000112sexually immature stage
  • UBERON:0018241prime adult stage
  • UBERON:0000104life cycle
3.80e3
  • 3.80e3
  • 4.26e3
  • 4.50e3
83.55
  • 83.55
  • 81.53
  • 80.52
AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0001987placenta
  • UBERON:0018241prime adult stage
  • UBERON:0000113post-juvenile adult stage
3.86e3
  • 3.86e3
  • 6.73e3
83.27
  • 83.27
  • 70.82
AEIR
  • AEIR
  • AEIR
UBERON:0000056ureter
  • UBERON:0000104life cycle
3.88e3
  • 3.88e3
83.17
  • 83.17
AEIR
  • AEIR
UBERON:0003126trachea
  • UBERON:0000104life cycle
3.89e3
  • 3.89e3
83.17
  • 83.17
AEIR
  • AEIR
UBERON:0002046thyroid gland
  • UBERON:0018241prime adult stage
3.92e3
  • 3.92e3
83.03
  • 83.03
AEIR
  • AEIR
UBERON:0001371gluteus medius
  • UBERON:0000104life cycle
3.97e3
  • 3.97e3
82.81
  • 82.81
AEIR
  • AEIR
UBERON:0002198neurohypophysis
  • UBERON:0000104life cycle
4.02e3
  • 4.02e3
82.59
  • 82.59
AEIR
  • AEIR
UBERON:0000362renal medulla
  • UBERON:0000104life cycle
4.06e3
  • 4.06e3
82.41
  • 82.41
AEIR
  • AEIR
UBERON:0001103diaphragm
  • UBERON:0000104life cycle
4.07e3
  • 4.07e3
82.37
  • 82.37
AEIR
  • AEIR
UBERON:0002106spleen
  • UBERON:0000104life cycle
  • UBERON:0018241prime adult stage
4.11e3
  • 4.11e3
  • 4.87e3
82.20
  • 82.20
  • 78.91
AEIR
  • AEIR
  • AEIR
UBERON:0005386olfactory segment of nasal mucosa
  • UBERON:0000104life cycle
4.12e3
  • 4.12e3
82.13
  • 82.13
AEIR
  • AEIR
UBERON:0002116ileum
  • UBERON:0018241prime adult stage
  • UBERON:0000104life cycle
4.18e3
  • 4.18e3
  • 4.35e3
81.90
  • 81.90
  • 81.13
AEIR
  • AEIR
  • AEIR
UBERON:0000007pituitary gland
  • UBERON:0018241prime adult stage
4.19e3
  • 4.19e3
81.82
  • 81.82
AEIR
  • AEIR
UBERON:0001044saliva-secreting gland
  • UBERON:0000104life cycle
4.20e3
  • 4.20e3
81.80
  • 81.80
AEIR
  • AEIR
UBERON:0001378rectus femoris
  • UBERON:0000104life cycle
4.30e3
  • 4.30e3
81.39
  • 81.39
AEIR
  • AEIR
UBERON:0001134skeletal muscle tissue
  • UBERON:0000104life cycle
  • UBERON:0018241prime adult stage
4.36e3
  • 4.36e3
  • 6.62e3
81.11
  • 81.11
  • 71.32
AEIR
  • AEIR
  • AEIR
UBERON:0015869retropharyngeal lymph node
  • UBERON:0000104life cycle
4.49e3
  • 4.49e3
80.53
  • 80.53
AEIR
  • AEIR
UBERON:0004716conceptus
  • UBERON:0000068embryo stage
4.51e3
  • 4.51e3
80.47
  • 80.47
AEIR
  • AEIR
UBERON:0002110gall bladder
  • UBERON:0000104life cycle
4.56e3
  • 4.56e3
80.24
  • 80.24
AEIR
  • AEIR
UBERON:0001296myometrium
  • UBERON:0000104life cycle
4.58e3
  • 4.58e3
80.17
  • 80.17
AEIR
  • AEIR
UBERON:0001381semimembranosus muscle
  • UBERON:0000104life cycle
  • UBERON:0018241prime adult stage
4.63e3
  • 4.63e3
  • 5.29e3
79.94
  • 79.94
  • 77.07
AEIR
  • AEIR
  • AEIR
UBERON:0001375semitendinosus
  • UBERON:0000104life cycle
  • UBERON:0018241prime adult stage
  • UBERON:0000113post-juvenile adult stage
4.63e3
  • 4.63e3
  • 5.39e3
  • 7.17e3
79.92
  • 79.92
  • 76.63
  • 68.92
AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0001477infraspinatus muscle
  • UBERON:0000104life cycle
  • UBERON:0018241prime adult stage
4.67e3
  • 4.67e3
  • 4.67e3
79.78
  • 79.78
  • 79.76
AEIR
  • AEIR
  • AEIR
UBERON:0002247uterine horn
  • UBERON:0018241prime adult stage
4.72e3
  • 4.72e3
79.55
  • 79.55
AEIR
  • AEIR
UBERON:0001723tongue
  • UBERON:0018241prime adult stage
4.88e3
  • 4.88e3
78.86
  • 78.86
AEIR
  • AEIR
UBERON:0003984uterine tube infundibulum
  • UBERON:0000104life cycle
4.91e3
  • 4.91e3
78.73
  • 78.73
AEIR
  • AEIR
UBERON:0007625pigment epithelium of eye
  • UBERON:0000104life cycle
4.98e3
  • 4.98e3
78.44
  • 78.44
AEIR
  • AEIR
UBERON:0012648ampulla of uterine tube
  • UBERON:0000104life cycle
5.04e3
  • 5.04e3
78.16
  • 78.16
AEIR
  • AEIR
CL:0000711cumulus cell
  • UBERON:0000104life cycle
5.07e3
  • 5.07e3
78.05
  • 78.05
AEIR
  • AEIR
UBERON:0001509triceps brachii
  • UBERON:0000104life cycle
  • UBERON:0018241prime adult stage
5.09e3
  • 5.09e3
  • 5.09e3
77.95
  • 77.95
  • 77.94
AEIR
  • AEIR
  • AEIR
UBERON:0001870frontal cortex
  • UBERON:0000104life cycle
5.10e3
  • 5.10e3
77.89
  • 77.89
AEIR
  • AEIR
UBERON:0004703dorsal thalamus
  • UBERON:0018241prime adult stage
5.12e3
  • 5.12e3
77.83
  • 77.83
AEIR
  • AEIR
UBERON:0001111intercostal muscle
  • UBERON:0000104life cycle
5.14e3
  • 5.14e3
77.72
  • 77.72
AEIR
  • AEIR
UBERON:0002383supraspinatus muscle
  • UBERON:0018241prime adult stage
  • UBERON:0000104life cycle
5.31e3
  • 5.31e3
  • 5.31e3
76.97
  • 76.97
  • 76.97
AEIR
  • AEIR
  • AEIR
CL:0000503theca cell
  • UBERON:0018241prime adult stage
5.33e3
  • 5.33e3
76.91
  • 76.91
AEIR
  • AEIR
UBERON:0002114duodenum
  • UBERON:0000104life cycle
5.39e3
  • 5.39e3
76.62
  • 76.62
AEIR
  • AEIR
UBERON:0001913milk
  • UBERON:0000113post-juvenile adult stage
5.58e3
  • 5.58e3
75.82
  • 75.82
AEIR
  • AEIR
UBERON:0002037cerebellum
  • UBERON:0000104life cycle
  • UBERON:0018241prime adult stage
5.64e3
  • 5.64e3
  • 8.89e3
75.57
  • 75.57
  • 61.46
AEIR
  • AEIR
  • AEIR
CL:0000775neutrophil
  • UBERON:0018241prime adult stage
5.72e3
  • 5.72e3
75.21
  • 75.21
AEIR
  • AEIR
UBERON:0000948heart
  • UBERON:0000104life cycle
  • UBERON:0018241prime adult stage
5.75e3
  • 5.75e3
  • 6.08e3
75.07
  • 75.07
  • 73.67
AEIR
  • AEIR
  • AEIR
UBERON:0000178blood
  • UBERON:0018241prime adult stage
5.90e3
  • 5.90e3
74.45
  • 74.45
AEIR
  • AEIR
UBERON:0016538temporal cortex
  • UBERON:0000104life cycle
6.14e3
  • 6.14e3
73.41
  • 73.41
AEIR
  • AEIR
UBERON:0004358caput epididymis
  • UBERON:0018241prime adult stage
6.19e3
  • 6.19e3
73.17
  • 73.17
AEIR
  • AEIR
UBERON:0001401longissimus thoracis muscle
  • UBERON:0018241prime adult stage
  • UBERON:0000104life cycle
6.42e3
  • 6.42e3
  • 1.02e4
72.16
  • 72.16
  • 55.65
AEIR
  • AEIR
  • AEIR
UBERON:0003309floor plate of diencephalon
  • UBERON:0018241prime adult stage
6.45e3
  • 6.45e3
72.04
  • 72.04
AEIR
  • AEIR
UBERON:0002081cardiac atrium
  • UBERON:0000104life cycle
  • UBERON:0018241prime adult stage
6.46e3
  • 6.46e3
  • 6.50e3
71.99
  • 71.99
  • 71.83
AEIR
  • AEIR
  • AEIR
UBERON:0001954Ammon's horn
  • UBERON:0000068embryo stage
6.50e3
  • 6.50e3
71.82
  • 71.82
AEIR
  • AEIR
UBERON:0000992female gonad
  • UBERON:0018241prime adult stage
7.07e3
  • 7.07e3
69.36
  • 69.36
AEIR
  • AEIR
CL:0000501granulosa cell
  • UBERON:0018241prime adult stage
7.38e3
  • 7.38e3
68.02
  • 68.02
AEIR
  • AEIR
UBERON:0001898hypothalamus
  • UBERON:0000104life cycle
8.44e3
  • 8.44e3
63.43
  • 63.43
AEIR
  • AEIR
CL:0000017spermatocyte
  • UBERON:0018241prime adult stage
8.69e3
  • 8.69e3
62.35
  • 62.35
AEIR
  • AEIR
UBERON:0000473testis
  • UBERON:0000113post-juvenile adult stage
  • UBERON:0018241prime adult stage
  • UBERON:0000112sexually immature stage
  • UBERON:0000104life cycle
8.72e3
  • 8.72e3
  • 1.00e4
  • 1.17e4
  • 1.37e4
62.20
  • 62.20
  • 56.67
  • 49.12
  • 40.61
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0000451prefrontal cortex
  • UBERON:0018241prime adult stage
9.09e3
  • 9.09e3
60.59
  • 60.59
AEIR
  • AEIR
CL:0000018spermatid
  • UBERON:0018241prime adult stage
9.50e3
  • 9.50e3
58.83
  • 58.83
AEIR
  • AEIR
UBERON:0002021occipital lobe
  • UBERON:0018241prime adult stage
1.04e4
  • 1.04e4
54.91
  • 54.91
AEIR
  • AEIR
Sources
AAffymetrix
EEST
IIn Situ
RRNA-Seq
data
no data
Rank scores
3.25e4lightgrey: low confidence scores
 important score variation

Rank scores of expression calls are normalized across genes, conditions and species. Low score means that the gene is highly expressed in the condition. Max rank score in all species: 4.10e4. Min rank score varies across species.

Expression scores of expression calls use the minimum and maximum Rank of the species to normalize the expression to a value between 0 and 100. Low score means that the gene is lowly expressed in the condition.

Sources of annotations to anatomy and development:
  • RNA-Seq data: Bgee
Sources of raw data:
  • RNA-Seq data: GEO

Orthologs
Taxon nameSpecies with orthologsGene(s)Expression comparisonSee details
Cetartiodactyla1 species1 geneCompare expression
Laurasiatheria5 species5 genesCompare expression
Boreoeutheria13 species13 genesCompare expression
Theria14 species14 genesCompare expression
Mammalia15 species15 genesCompare expression
Amniota17 species17 genesCompare expression
Tetrapoda18 species18 genesCompare expression
Euteleostomi19 species19 genesCompare expression
Bilateria25 species25 genesCompare expression

Orthology information comes from OMA : ENSBTAG00000021832.

Paralogs (same species)
Taxon nameGene(s)Expression comparisonSee details
Chordata1 geneCompare expression

Paralogy information comes from OMA : ENSBTAG00000021832.

Cross-references

EnsemblENSBTAG00000021832 (HMGCL)
HGNCHGNC:5005 (HMGCL)
EMBLBC118276, U41409
Uniprot/SWISSPROTHMGCL_BOVIN, Q29448

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