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C. lupus familiaris Gene: TIMP4 - ENSCAFG00000005002 - Canis lupus familiaris (dog)

General information

Ensembl IDENSCAFG00000005002
NameTIMP4
DescriptionTIMP metallopeptidase inhibitor 4 [Source:HGNC Symbol;Acc:HGNC:11823]
OrganismCanis lupus familiaris (dog)
Orthologs(s)15 orthologs
Paralog(s)2 paralogs

Expression

Anat. entity IDAnatomical entityDevelopmental stage(s)Rank scoreExpression scoreSources
UBERON:0002371bone marrow
  • UBERON:0007222late adult stage
1.89e3
  • 1.89e3
91.57
  • 91.57
AEIR
  • AEIR
UBERON:0000014zone of skin
  • UBERON:0007222late adult stage
  • UBERON:0000104life cycle
3.03e3
  • 3.03e3
  • 1.13e4
86.47
  • 86.47
  • 49.63
AEIR
  • AEIR
  • AEIR
UBERON:0001013adipose tissue
  • UBERON:0007222late adult stage
3.42e3
  • 3.42e3
84.71
  • 84.71
AEIR
  • AEIR
UBERON:0002048lung
  • UBERON:0007222late adult stage
  • UBERON:0000104life cycle
  • UBERON:0000112sexually immature stage
4.79e3
  • 4.79e3
  • 9.58e3
  • 1.64e4
78.59
  • 78.59
  • 57.18
  • 26.62
AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0001134skeletal muscle tissue
  • UBERON:0007222late adult stage
  • UBERON:0000104life cycle
6.03e3
  • 6.03e3
  • 7.93e3
73.02
  • 73.02
  • 64.55
AEIR
  • AEIR
  • AEIR
UBERON:0000029lymph node
  • UBERON:0007222late adult stage
  • UBERON:0000104life cycle
6.18e3
  • 6.18e3
  • 1.06e4
72.38
  • 72.38
  • 52.55
AEIR
  • AEIR
  • AEIR
UBERON:0003382cardiac muscle of left ventricle
  • UBERON:0000104life cycle
6.25e3
  • 6.25e3
72.07
  • 72.07
AEIR
  • AEIR
UBERON:0002037cerebellum
  • UBERON:0007222late adult stage
  • UBERON:0000104life cycle
6.58e3
  • 6.58e3
  • 8.65e3
70.57
  • 70.57
  • 61.34
AEIR
  • AEIR
  • AEIR
UBERON:0002080heart right ventricle
  • UBERON:0007222late adult stage
6.95e3
  • 6.95e3
68.93
  • 68.93
AEIR
  • AEIR
UBERON:0002079left cardiac atrium
  • UBERON:0007222late adult stage
7.04e3
  • 7.04e3
68.52
  • 68.52
AEIR
  • AEIR
UBERON:0002418cartilage tissue
  • UBERON:0007222late adult stage
7.41e3
  • 7.41e3
66.87
  • 66.87
AEIR
  • AEIR
UBERON:0001135smooth muscle tissue
  • UBERON:0000104life cycle
7.85e3
  • 7.85e3
64.92
  • 64.92
AEIR
  • AEIR
UBERON:0002084heart left ventricle
  • UBERON:0007222late adult stage
  • UBERON:0018241prime adult stage
8.56e3
  • 8.56e3
  • 1.08e4
61.71
  • 61.71
  • 51.67
AEIR
  • AEIR
  • AEIR
UBERON:0001723tongue
  • UBERON:0000113post-juvenile adult stage
8.60e3
  • 8.60e3
61.54
  • 61.54
AEIR
  • AEIR
UBERON:0000948heart
  • UBERON:0000104life cycle
  • UBERON:0000112sexually immature stage
8.67e3
  • 8.67e3
  • 1.61e4
61.24
  • 61.24
  • 27.83
AEIR
  • AEIR
  • AEIR
UBERON:0002369adrenal gland
  • UBERON:0007222late adult stage
  • UBERON:0000104life cycle
9.19e3
  • 9.19e3
  • 1.11e4
58.90
  • 58.90
  • 50.25
AEIR
  • AEIR
  • AEIR
UBERON:0002240spinal cord
  • UBERON:0000104life cycle
1.00e4
  • 1.00e4
55.07
  • 55.07
AEIR
  • AEIR
UBERON:0002078right cardiac atrium
  • UBERON:0007222late adult stage
1.03e4
  • 1.03e4
54.01
  • 54.01
AEIR
  • AEIR
UBERON:0001987placenta
  • UBERON:0000113post-juvenile adult stage
1.10e4
  • 1.10e4
50.88
  • 50.88
AEIR
  • AEIR
UBERON:0002021occipital lobe
  • UBERON:0000113post-juvenile adult stage
1.10e4
  • 1.10e4
50.63
  • 50.63
AEIR
  • AEIR
UBERON:0001871temporal lobe
  • UBERON:0000113post-juvenile adult stage
1.11e4
  • 1.11e4
50.27
  • 50.27
AEIR
  • AEIR
UBERON:0001235adrenal cortex
  • UBERON:0018241prime adult stage
1.12e4
  • 1.12e4
49.73
  • 49.73
AEIR
  • AEIR
UBERON:0000059large intestine
  • UBERON:0000113post-juvenile adult stage
1.15e4
  • 1.15e4
48.50
  • 48.50
AEIR
  • AEIR
UBERON:0002135mitral valve
  • UBERON:0018241prime adult stage
1.20e4
  • 1.20e4
46.29
  • 46.29
AEIR
  • AEIR
UBERON:0001259mucosa of urinary bladder
  • UBERON:0000104life cycle
1.21e4
  • 1.21e4
46.03
  • 46.03
AEIR
  • AEIR
UBERON:0002106spleen
  • UBERON:0007222late adult stage
  • UBERON:0000104life cycle
  • UBERON:0000113post-juvenile adult stage
1.21e4
  • 1.21e4
  • 1.42e4
  • 1.48e4
46.01
  • 46.01
  • 36.47
  • 34.01
AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0002264olfactory bulb
  • UBERON:0000104life cycle
1.21e4
  • 1.21e4
45.77
  • 45.77
AEIR
  • AEIR
UBERON:0001255urinary bladder
  • UBERON:0007222late adult stage
1.24e4
  • 1.24e4
44.51
  • 44.51
AEIR
  • AEIR
UBERON:0002370thymus
  • UBERON:0000104life cycle
1.26e4
  • 1.26e4
43.65
  • 43.65
AEIR
  • AEIR
UBERON:0001264pancreas
  • UBERON:0007222late adult stage
  • UBERON:0000113post-juvenile adult stage
  • UBERON:0000104life cycle
1.27e4
  • 1.27e4
  • 1.42e4
  • 1.48e4
43.10
  • 43.10
  • 36.51
  • 33.67
AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0000956cerebral cortex
  • UBERON:0000104life cycle
1.28e4
  • 1.28e4
42.98
  • 42.98
AEIR
  • AEIR
UBERON:0001911mammary gland
  • UBERON:0018241prime adult stage
  • UBERON:0000104life cycle
1.30e4
  • 1.30e4
  • 1.39e4
41.72
  • 41.72
  • 37.77
AEIR
  • AEIR
  • AEIR
UBERON:0002046thyroid gland
  • UBERON:0007222late adult stage
1.32e4
  • 1.32e4
41.12
  • 41.12
AEIR
  • AEIR
UBERON:0000178blood
  • UBERON:0000104life cycle
1.34e4
  • 1.34e4
40.15
  • 40.15
AEIR
  • AEIR
UBERON:0000451prefrontal cortex
  • UBERON:0018241prime adult stage
1.35e4
  • 1.35e4
39.62
  • 39.62
AEIR
  • AEIR
UBERON:0000007pituitary gland
  • UBERON:0007222late adult stage
  • UBERON:0018241prime adult stage
1.36e4
  • 1.36e4
  • 1.52e4
39.29
  • 39.29
  • 31.81
AEIR
  • AEIR
  • AEIR
UBERON:0001870frontal cortex
  • UBERON:0007222late adult stage
1.36e4
  • 1.36e4
39.23
  • 39.23
AEIR
  • AEIR
UBERON:0001155colon
  • UBERON:0007222late adult stage
  • UBERON:0000104life cycle
1.36e4
  • 1.36e4
  • 1.47e4
39.20
  • 39.20
  • 34.27
AEIR
  • AEIR
  • AEIR
UBERON:0002073hair follicle
  • UBERON:0000104life cycle
1.37e4
  • 1.37e4
38.65
  • 38.65
AEIR
  • AEIR
UBERON:0000945stomach
  • UBERON:0007222late adult stage
  • UBERON:0000113post-juvenile adult stage
1.38e4
  • 1.38e4
  • 1.59e4
38.37
  • 38.37
  • 28.83
AEIR
  • AEIR
  • AEIR
UBERON:0001044saliva-secreting gland
  • UBERON:0007222late adult stage
1.41e4
  • 1.41e4
37.17
  • 37.17
AEIR
  • AEIR
UBERON:0000362renal medulla
  • UBERON:0007222late adult stage
1.41e4
  • 1.41e4
37.04
  • 37.04
AEIR
  • AEIR
UBERON:0000992female gonad
  • UBERON:0000104life cycle
1.41e4
  • 1.41e4
36.77
  • 36.77
AEIR
  • AEIR
UBERON:0010533metanephros cortex
  • UBERON:0007222late adult stage
1.47e4
  • 1.47e4
34.40
  • 34.40
AEIR
  • AEIR
UBERON:0016540occipital cortex
  • UBERON:0007222late adult stage
1.48e4
  • 1.48e4
33.73
  • 33.73
AEIR
  • AEIR
UBERON:0002107liver
  • UBERON:0007222late adult stage
  • UBERON:0018241prime adult stage
  • UBERON:0000104life cycle
  • UBERON:0000112sexually immature stage
  • UBERON:0000113post-juvenile adult stage
1.49e4
  • 1.49e4
  • 1.56e4
  • 1.64e4
  • 1.68e4
  • 1.73e4
33.43
  • 33.43
  • 30.38
  • 26.75
  • 24.78
  • 22.72
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0001898hypothalamus
  • UBERON:0000104life cycle
1.49e4
  • 1.49e4
33.28
  • 33.28
AEIR
  • AEIR
UBERON:0002108small intestine
  • UBERON:0007222late adult stage
  • UBERON:0000113post-juvenile adult stage
1.51e4
  • 1.51e4
  • 1.53e4
32.39
  • 32.39
  • 31.55
AEIR
  • AEIR
  • AEIR
UBERON:0000966retina
  • UBERON:0000104life cycle
1.53e4
  • 1.53e4
31.71
  • 31.71
AEIR
  • AEIR
UBERON:0000004nose
  • UBERON:0000104life cycle
1.57e4
  • 1.57e4
29.86
  • 29.86
AEIR
  • AEIR
UBERON:0000082adult mammalian kidney
  • UBERON:0018241prime adult stage
  • UBERON:0000112sexually immature stage
1.60e4
  • 1.60e4
  • 1.68e4
28.32
  • 28.32
  • 25.08
AEIR
  • AEIR
  • AEIR
UBERON:0000033head
  • UBERON:0000112sexually immature stage
1.62e4
  • 1.62e4
27.53
  • 27.53
AEIR
  • AEIR
Sources
AAffymetrix
EEST
IIn Situ
RRNA-Seq
data
no data
Rank scores
3.25e4lightgrey: low confidence scores

important score variation

Rank scores of expression calls are normalized across genes, conditions and species. Low score means that the gene is highly expressed in the condition. Max rank score in all species: 4.10e4. Min rank score varies across species.

Expression scores of expression calls use the minimum and maximum Rank of the species to normalize the expression to a value between 0 and 100. Low score means that the gene is lowly expressed in the condition.

Sources of annotations to anatomy and development:
  • RNA-Seq data: Bgee
Sources of raw data:
  • RNA-Seq data: GEO

Orthologs

Taxon nameSpecies with orthologsGene(s)Expression comparisonSee details
Carnivora1 species1 geneCompare expression
Laurasiatheria3 species3 genesCompare expression
Boreoeutheria11 species11 genesCompare expression
Theria12 species12 genesCompare expression
Amniota14 species14 genesCompare expression
Euteleostomi15 species15 genesCompare expression

Orthology information comes from OMA : ENSCAFG00000005002.

Paralogs (same species)

Taxon nameGene(s)Expression comparisonSee details
Vertebrata2 genesCompare expression

Paralogy information comes from OMA : ENSCAFG00000005002.

Cross-references

EnsemblENSCAFG00000005002 (TIMP4)
HGNCHGNC:11823 (TIMP4)
EMBLAAEX03012062
Uniprot/SPTREMBLE2RPY3, E2RPY3_CANLF

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