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C. lupus familiaris Gene: BRCA2 - ENSCAFG00000006383 - Canis lupus familiaris (dog)

General information

Ensembl IDENSCAFG00000006383
NameBRCA2
Descriptionbreast cancer 2 [Source:HGNC Symbol;Acc:HGNC:1101]
OrganismCanis lupus familiaris (dog)
Synonym(s)brcc2, facd, fad, fad1, fancd, fancd1, xrcc11
Orthologs(s)16 orthologs

Expression

Anat. entity IDAnatomical entityDevelopmental stage(s)Rank scoreExpression scoreSources
UBERON:0002048lung
  • UBERON:0000112sexually immature stage
  • UBERON:0007222late adult stage
  • UBERON:0000104life cycle
7.01e3
  • 7.01e3
  • 1.42e4
  • 1.55e4
68.64
  • 68.64
  • 36.44
  • 30.73
AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0002107liver
  • UBERON:0000112sexually immature stage
  • UBERON:0018241prime adult stage
  • UBERON:0000104life cycle
  • UBERON:0007222late adult stage
  • UBERON:0000113post-juvenile adult stage
8.14e3
  • 8.14e3
  • 1.16e4
  • 1.30e4
  • 1.38e4
  • 1.59e4
63.59
  • 63.59
  • 48.26
  • 42.00
  • 38.11
  • 28.75
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
CL:0000312keratinocyte
  • UBERON:0000104life cycle
8.50e3
  • 8.50e3
62.01
  • 62.01
AEIR
  • AEIR
UBERON:0002370thymus
  • UBERON:0000104life cycle
8.50e3
  • 8.50e3
62.00
  • 62.00
AEIR
  • AEIR
UBERON:0000955brain
  • UBERON:0018241prime adult stage
  • UBERON:0000104life cycle
8.61e3
  • 8.61e3
  • 1.63e4
61.51
  • 61.51
  • 27.29
AEIR
  • AEIR
  • AEIR
UBERON:0000948heart
  • UBERON:0000112sexually immature stage
  • UBERON:0000104life cycle
8.78e3
  • 8.78e3
  • 1.56e4
60.73
  • 60.73
  • 30.17
AEIR
  • AEIR
  • AEIR
UBERON:0000082adult mammalian kidney
  • UBERON:0000112sexually immature stage
  • UBERON:0018241prime adult stage
8.82e3
  • 8.82e3
  • 1.33e4
60.56
  • 60.56
  • 40.34
AEIR
  • AEIR
  • AEIR
UBERON:0000014zone of skin
  • UBERON:0000104life cycle
  • UBERON:0007222late adult stage
8.82e3
  • 8.82e3
  • 1.23e4
60.55
  • 60.55
  • 44.91
AEIR
  • AEIR
  • AEIR
UBERON:0000033head
  • UBERON:0000112sexually immature stage
9.53e3
  • 9.53e3
57.37
  • 57.37
AEIR
  • AEIR
UBERON:0000473testis
  • UBERON:0000104life cycle
1.04e4
  • 1.04e4
53.39
  • 53.39
AEIR
  • AEIR
UBERON:0000004nose
  • UBERON:0000104life cycle
1.09e4
  • 1.09e4
51.40
  • 51.40
AEIR
  • AEIR
UBERON:0002115jejunum
  • UBERON:0000104life cycle
1.14e4
  • 1.14e4
49.05
  • 49.05
AEIR
  • AEIR
UBERON:0000029lymph node
  • UBERON:0000104life cycle
  • UBERON:0007222late adult stage
1.16e4
  • 1.16e4
  • 1.26e4
48.16
  • 48.16
  • 43.62
AEIR
  • AEIR
  • AEIR
UBERON:0002073hair follicle
  • UBERON:0000104life cycle
1.18e4
  • 1.18e4
47.40
  • 47.40
AEIR
  • AEIR
UBERON:0001013adipose tissue
  • UBERON:0007222late adult stage
1.19e4
  • 1.19e4
46.94
  • 46.94
AEIR
  • AEIR
UBERON:0001155colon
  • UBERON:0000104life cycle
  • UBERON:0007222late adult stage
1.19e4
  • 1.19e4
  • 1.29e4
46.61
  • 46.61
  • 42.47
AEIR
  • AEIR
  • AEIR
UBERON:0002135mitral valve
  • UBERON:0018241prime adult stage
  • UBERON:0007222late adult stage
1.20e4
  • 1.20e4
  • 1.22e4
46.53
  • 46.53
  • 45.25
AEIR
  • AEIR
  • AEIR
UBERON:0001987placenta
  • UBERON:0000113post-juvenile adult stage
1.21e4
  • 1.21e4
45.92
  • 45.92
AEIR
  • AEIR
UBERON:0002106spleen
  • UBERON:0007222late adult stage
  • UBERON:0000104life cycle
  • UBERON:0000113post-juvenile adult stage
1.22e4
  • 1.22e4
  • 1.30e4
  • 1.55e4
45.43
  • 45.43
  • 41.93
  • 30.83
AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0001911mammary gland
  • UBERON:0000104life cycle
  • UBERON:0018241prime adult stage
1.24e4
  • 1.24e4
  • 1.24e4
44.73
  • 44.73
  • 44.60
AEIR
  • AEIR
  • AEIR
UBERON:0002418cartilage tissue
  • UBERON:0007222late adult stage
1.25e4
  • 1.25e4
44.30
  • 44.30
AEIR
  • AEIR
UBERON:0016540occipital cortex
  • UBERON:0007222late adult stage
1.25e4
  • 1.25e4
44.07
  • 44.07
AEIR
  • AEIR
UBERON:0001235adrenal cortex
  • UBERON:0018241prime adult stage
1.25e4
  • 1.25e4
43.96
  • 43.96
AEIR
  • AEIR
UBERON:0000178blood
  • UBERON:0000104life cycle
1.26e4
  • 1.26e4
43.80
  • 43.80
AEIR
  • AEIR
UBERON:0001259mucosa of urinary bladder
  • UBERON:0000104life cycle
1.28e4
  • 1.28e4
42.94
  • 42.94
AEIR
  • AEIR
UBERON:0003382cardiac muscle of left ventricle
  • UBERON:0000104life cycle
1.28e4
  • 1.28e4
42.77
  • 42.77
AEIR
  • AEIR
UBERON:0002080heart right ventricle
  • UBERON:0007222late adult stage
1.28e4
  • 1.28e4
42.75
  • 42.75
AEIR
  • AEIR
UBERON:0002371bone marrow
  • UBERON:0007222late adult stage
1.28e4
  • 1.28e4
42.73
  • 42.73
AEIR
  • AEIR
UBERON:0002108small intestine
  • UBERON:0007222late adult stage
  • UBERON:0000113post-juvenile adult stage
1.29e4
  • 1.29e4
  • 1.46e4
42.52
  • 42.52
  • 34.56
AEIR
  • AEIR
  • AEIR
UBERON:0001255urinary bladder
  • UBERON:0007222late adult stage
1.29e4
  • 1.29e4
42.26
  • 42.26
AEIR
  • AEIR
UBERON:0002078right cardiac atrium
  • UBERON:0007222late adult stage
1.30e4
  • 1.30e4
42.02
  • 42.02
AEIR
  • AEIR
UBERON:0002084heart left ventricle
  • UBERON:0007222late adult stage
  • UBERON:0018241prime adult stage
1.32e4
  • 1.32e4
  • 1.33e4
41.17
  • 41.17
  • 40.62
AEIR
  • AEIR
  • AEIR
UBERON:0000945stomach
  • UBERON:0007222late adult stage
  • UBERON:0000113post-juvenile adult stage
1.32e4
  • 1.32e4
  • 1.57e4
40.90
  • 40.90
  • 29.82
AEIR
  • AEIR
  • AEIR
UBERON:0001044saliva-secreting gland
  • UBERON:0007222late adult stage
1.34e4
  • 1.34e4
40.26
  • 40.26
AEIR
  • AEIR
UBERON:0002369adrenal gland
  • UBERON:0007222late adult stage
  • UBERON:0000104life cycle
1.35e4
  • 1.35e4
  • 1.41e4
39.64
  • 39.64
  • 36.76
AEIR
  • AEIR
  • AEIR
UBERON:0001870frontal cortex
  • UBERON:0007222late adult stage
1.36e4
  • 1.36e4
39.40
  • 39.40
AEIR
  • AEIR
UBERON:0001134skeletal muscle tissue
  • UBERON:0007222late adult stage
  • UBERON:0000104life cycle
1.36e4
  • 1.36e4
  • 1.46e4
39.31
  • 39.31
  • 34.85
AEIR
  • AEIR
  • AEIR
UBERON:0000966retina
  • UBERON:0000104life cycle
1.36e4
  • 1.36e4
39.10
  • 39.10
AEIR
  • AEIR
UBERON:0001264pancreas
  • UBERON:0000104life cycle
  • UBERON:0007222late adult stage
  • UBERON:0000113post-juvenile adult stage
1.39e4
  • 1.39e4
  • 1.44e4
  • 1.69e4
37.86
  • 37.86
  • 35.83
  • 24.46
AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0002037cerebellum
  • UBERON:0007222late adult stage
  • UBERON:0000104life cycle
1.40e4
  • 1.40e4
  • 1.43e4
37.57
  • 37.57
  • 36.11
AEIR
  • AEIR
  • AEIR
UBERON:0002240spinal cord
  • UBERON:0000104life cycle
1.44e4
  • 1.44e4
35.48
  • 35.48
AEIR
  • AEIR
UBERON:0002046thyroid gland
  • UBERON:0007222late adult stage
1.44e4
  • 1.44e4
35.47
  • 35.47
AEIR
  • AEIR
UBERON:0001135smooth muscle tissue
  • UBERON:0000104life cycle
1.45e4
  • 1.45e4
35.30
  • 35.30
AEIR
  • AEIR
UBERON:0000451prefrontal cortex
  • UBERON:0018241prime adult stage
1.46e4
  • 1.46e4
34.55
  • 34.55
AEIR
  • AEIR
UBERON:0000007pituitary gland
  • UBERON:0018241prime adult stage
  • UBERON:0007222late adult stage
1.47e4
  • 1.47e4
  • 1.50e4
34.14
  • 34.14
  • 32.93
AEIR
  • AEIR
  • AEIR
UBERON:0000992female gonad
  • UBERON:0000104life cycle
1.48e4
  • 1.48e4
34.00
  • 34.00
AEIR
  • AEIR
UBERON:0010533metanephros cortex
  • UBERON:0007222late adult stage
1.51e4
  • 1.51e4
32.53
  • 32.53
AEIR
  • AEIR
UBERON:0002264olfactory bulb
  • UBERON:0000104life cycle
1.54e4
  • 1.54e4
31.25
  • 31.25
AEIR
  • AEIR
UBERON:0000362renal medulla
  • UBERON:0007222late adult stage
1.56e4
  • 1.56e4
30.45
  • 30.45
AEIR
  • AEIR
UBERON:0001871temporal lobe
  • UBERON:0000113post-juvenile adult stage
1.63e4
  • 1.63e4
27.06
  • 27.06
AEIR
  • AEIR
UBERON:0001898hypothalamus
  • UBERON:0000104life cycle
1.71e4
  • 1.71e4
23.47
  • 23.47
AEIR
  • AEIR
Sources
AAffymetrix
EEST
IIn Situ
RRNA-Seq
data
no data
Rank scores
3.25e4lightgrey: low confidence scores

important score variation

Rank scores of expression calls are normalized across genes, conditions and species. Low score means that the gene is highly expressed in the condition. Max rank score in all species: 4.10e4. Min rank score varies across species.

Expression scores of expression calls use the minimum and maximum Rank of the species to normalize the expression to a value between 0 and 100. Low score means that the gene is lowly expressed in the condition.

Sources of annotations to anatomy and development:
  • RNA-Seq data: Bgee
Sources of raw data:
  • RNA-Seq data: GEO

Orthologs

Taxon nameSpecies with orthologsGene(s)Expression comparisonSee details
Carnivora1 species1 geneCompare expression
Laurasiatheria5 species5 genesCompare expression
Boreoeutheria13 species13 genesCompare expression
Theria14 species14 genesCompare expression
Mammalia15 species15 genesCompare expression
Amniota16 species16 genesCompare expression

Orthology information comes from OMA : ENSCAFG00000006383.

Cross-references

EnsemblENSCAFG00000006383 (BRCA2)
HGNCHGNC:1101 (BRCA2)
EMBLAAEX03014218
Uniprot/SPTREMBLF1Q0X3, F1Q0X3_CANLF

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