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C. lupus familiaris Gene: SIGIRR - ENSCAFG00000006505 - Canis lupus familiaris (dog)

General information

Ensembl IDENSCAFG00000006505
NameSIGIRR
Descriptionsingle immunoglobulin and toll-interleukin 1 receptor (TIR) domain [Source:HGNC Symbol;Acc:HGNC:30575]
OrganismCanis lupus familiaris (dog)
Synonym(s)tir8
Orthologs(s)14 orthologs

Expression

Anat. entity IDAnatomical entityDevelopmental stage(s)Rank scoreExpression scoreSources
UBERON:0000178blood
  • UBERON:0000104life cycle
1.79e3
  • 1.79e3
92.01
  • 92.01
AEIR
  • AEIR
UBERON:0001264pancreas
  • UBERON:0000113post-juvenile adult stage
  • UBERON:0000104life cycle
  • UBERON:0007222late adult stage
2.00e3
  • 2.00e3
  • 2.43e3
  • 2.97e3
91.07
  • 91.07
  • 89.13
  • 86.74
AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0002115jejunum
  • UBERON:0000104life cycle
2.79e3
  • 2.79e3
87.52
  • 87.52
AEIR
  • AEIR
UBERON:0002113kidney
  • UBERON:0000104life cycle
2.86e3
  • 2.86e3
87.20
  • 87.20
AEIR
  • AEIR
UBERON:0000945stomach
  • UBERON:0007222late adult stage
  • UBERON:0000113post-juvenile adult stage
3.01e3
  • 3.01e3
  • 4.16e3
86.56
  • 86.56
  • 81.39
AEIR
  • AEIR
  • AEIR
UBERON:0000059large intestine
  • UBERON:0000113post-juvenile adult stage
3.43e3
  • 3.43e3
84.65
  • 84.65
AEIR
  • AEIR
UBERON:0002048lung
  • UBERON:0000104life cycle
  • UBERON:0007222late adult stage
  • UBERON:0000112sexually immature stage
3.64e3
  • 3.64e3
  • 4.99e3
  • 1.07e4
83.74
  • 83.74
  • 77.69
  • 52.14
AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0002108small intestine
  • UBERON:0000113post-juvenile adult stage
  • UBERON:0007222late adult stage
3.73e3
  • 3.73e3
  • 7.33e3
83.34
  • 83.34
  • 67.21
AEIR
  • AEIR
  • AEIR
UBERON:0002107liver
  • UBERON:0000113post-juvenile adult stage
  • UBERON:0000104life cycle
  • UBERON:0007222late adult stage
  • UBERON:0018241prime adult stage
  • UBERON:0000112sexually immature stage
3.80e3
  • 3.80e3
  • 3.92e3
  • 5.27e3
  • 6.94e3
  • 7.16e3
83.03
  • 83.03
  • 82.49
  • 76.44
  • 68.96
  • 68.00
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0001155colon
  • UBERON:0000104life cycle
  • UBERON:0007222late adult stage
3.89e3
  • 3.89e3
  • 9.33e3
82.59
  • 82.59
  • 58.28
AEIR
  • AEIR
  • AEIR
UBERON:0002106spleen
  • UBERON:0000104life cycle
  • UBERON:0000113post-juvenile adult stage
  • UBERON:0007222late adult stage
4.07e3
  • 4.07e3
  • 4.99e3
  • 5.21e3
81.81
  • 81.81
  • 77.69
  • 76.70
AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0002370thymus
  • UBERON:0000104life cycle
4.10e3
  • 4.10e3
81.67
  • 81.67
AEIR
  • AEIR
UBERON:0000029lymph node
  • UBERON:0007222late adult stage
  • UBERON:0000104life cycle
4.10e3
  • 4.10e3
  • 1.28e4
81.67
  • 81.67
  • 42.63
AEIR
  • AEIR
  • AEIR
CL:0000094granulocyte
  • UBERON:0000104life cycle
4.32e3
  • 4.32e3
80.69
  • 80.69
AEIR
  • AEIR
UBERON:0000966retina
  • UBERON:0000104life cycle
4.58e3
  • 4.58e3
79.54
  • 79.54
AEIR
  • AEIR
UBERON:0002371bone marrow
  • UBERON:0007222late adult stage
4.74e3
  • 4.74e3
78.80
  • 78.80
AEIR
  • AEIR
UBERON:0002046thyroid gland
  • UBERON:0007222late adult stage
5.61e3
  • 5.61e3
74.93
  • 74.93
AEIR
  • AEIR
UBERON:0000362renal medulla
  • UBERON:0007222late adult stage
6.30e3
  • 6.30e3
71.83
  • 71.83
AEIR
  • AEIR
UBERON:0010533metanephros cortex
  • UBERON:0007222late adult stage
6.42e3
  • 6.42e3
71.32
  • 71.32
AEIR
  • AEIR
UBERON:0002418cartilage tissue
  • UBERON:0007222late adult stage
6.56e3
  • 6.56e3
70.67
  • 70.67
AEIR
  • AEIR
UBERON:0000014zone of skin
  • UBERON:0007222late adult stage
  • UBERON:0000104life cycle
6.82e3
  • 6.82e3
  • 1.30e4
69.53
  • 69.53
  • 41.98
AEIR
  • AEIR
  • AEIR
UBERON:0001723tongue
  • UBERON:0000113post-juvenile adult stage
6.99e3
  • 6.99e3
68.76
  • 68.76
AEIR
  • AEIR
UBERON:0000082adult mammalian kidney
  • UBERON:0018241prime adult stage
  • UBERON:0000112sexually immature stage
7.06e3
  • 7.06e3
  • 1.07e4
68.44
  • 68.44
  • 52.03
AEIR
  • AEIR
  • AEIR
UBERON:0001911mammary gland
  • UBERON:0018241prime adult stage
  • UBERON:0000104life cycle
7.11e3
  • 7.11e3
  • 7.80e3
68.21
  • 68.21
  • 65.10
AEIR
  • AEIR
  • AEIR
UBERON:0001044saliva-secreting gland
  • UBERON:0007222late adult stage
7.66e3
  • 7.66e3
65.75
  • 65.75
AEIR
  • AEIR
UBERON:0000948heart
  • UBERON:0000104life cycle
  • UBERON:0000112sexually immature stage
7.67e3
  • 7.67e3
  • 1.20e4
65.72
  • 65.72
  • 46.18
AEIR
  • AEIR
  • AEIR
UBERON:0002084heart left ventricle
  • UBERON:0018241prime adult stage
  • UBERON:0007222late adult stage
7.69e3
  • 7.69e3
  • 9.01e3
65.60
  • 65.60
  • 59.73
AEIR
  • AEIR
  • AEIR
UBERON:0001134skeletal muscle tissue
  • UBERON:0000104life cycle
  • UBERON:0007222late adult stage
7.76e3
  • 7.76e3
  • 9.60e3
65.31
  • 65.31
  • 57.07
AEIR
  • AEIR
  • AEIR
UBERON:0000992female gonad
  • UBERON:0000104life cycle
7.80e3
  • 7.80e3
65.11
  • 65.11
AEIR
  • AEIR
UBERON:0001135smooth muscle tissue
  • UBERON:0000104life cycle
7.82e3
  • 7.82e3
65.06
  • 65.06
AEIR
  • AEIR
UBERON:0002135mitral valve
  • UBERON:0007222late adult stage
  • UBERON:0018241prime adult stage
8.04e3
  • 8.04e3
  • 1.07e4
64.06
  • 64.06
  • 52.11
AEIR
  • AEIR
  • AEIR
UBERON:0002369adrenal gland
  • UBERON:0000104life cycle
  • UBERON:0007222late adult stage
8.49e3
  • 8.49e3
  • 1.06e4
62.06
  • 62.06
  • 52.56
AEIR
  • AEIR
  • AEIR
CL:0000312keratinocyte
  • UBERON:0000104life cycle
8.49e3
  • 8.49e3
62.02
  • 62.02
AEIR
  • AEIR
UBERON:0001013adipose tissue
  • UBERON:0007222late adult stage
8.58e3
  • 8.58e3
61.66
  • 61.66
AEIR
  • AEIR
UBERON:0003382cardiac muscle of left ventricle
  • UBERON:0000104life cycle
8.89e3
  • 8.89e3
60.24
  • 60.24
AEIR
  • AEIR
UBERON:0001259mucosa of urinary bladder
  • UBERON:0000104life cycle
8.91e3
  • 8.91e3
60.15
  • 60.15
AEIR
  • AEIR
UBERON:0002073hair follicle
  • UBERON:0000104life cycle
8.97e3
  • 8.97e3
59.87
  • 59.87
AEIR
  • AEIR
UBERON:0001987placenta
  • UBERON:0000113post-juvenile adult stage
9.03e3
  • 9.03e3
59.64
  • 59.64
AEIR
  • AEIR
UBERON:0000007pituitary gland
  • UBERON:0018241prime adult stage
  • UBERON:0007222late adult stage
9.19e3
  • 9.19e3
  • 1.09e4
58.88
  • 58.88
  • 51.10
AEIR
  • AEIR
  • AEIR
UBERON:0002080heart right ventricle
  • UBERON:0007222late adult stage
9.37e3
  • 9.37e3
58.09
  • 58.09
AEIR
  • AEIR
UBERON:0002078right cardiac atrium
  • UBERON:0007222late adult stage
1.05e4
  • 1.05e4
53.00
  • 53.00
AEIR
  • AEIR
UBERON:0000004nose
  • UBERON:0000104life cycle
1.10e4
  • 1.10e4
50.63
  • 50.63
AEIR
  • AEIR
UBERON:0001235adrenal cortex
  • UBERON:0018241prime adult stage
1.12e4
  • 1.12e4
49.74
  • 49.74
AEIR
  • AEIR
UBERON:0001255urinary bladder
  • UBERON:0007222late adult stage
1.12e4
  • 1.12e4
49.70
  • 49.70
AEIR
  • AEIR
UBERON:0002021occipital lobe
  • UBERON:0000113post-juvenile adult stage
1.18e4
  • 1.18e4
47.43
  • 47.43
AEIR
  • AEIR
UBERON:0001871temporal lobe
  • UBERON:0000113post-juvenile adult stage
1.25e4
  • 1.25e4
44.29
  • 44.29
AEIR
  • AEIR
UBERON:0002240spinal cord
  • UBERON:0000104life cycle
1.28e4
  • 1.28e4
42.77
  • 42.77
AEIR
  • AEIR
UBERON:0000033head
  • UBERON:0000112sexually immature stage
1.34e4
  • 1.34e4
40.00
  • 40.00
AEIR
  • AEIR
UBERON:0001898hypothalamus
  • UBERON:0000104life cycle
1.36e4
  • 1.36e4
38.97
  • 38.97
AEIR
  • AEIR
UBERON:0002037cerebellum
  • UBERON:0000104life cycle
  • UBERON:0007222late adult stage
1.42e4
  • 1.42e4
  • 1.44e4
36.45
  • 36.45
  • 35.81
AEIR
  • AEIR
  • AEIR
UBERON:0000451prefrontal cortex
  • UBERON:0018241prime adult stage
1.42e4
  • 1.42e4
36.44
  • 36.44
AEIR
  • AEIR
UBERON:0001870frontal cortex
  • UBERON:0007222late adult stage
1.45e4
  • 1.45e4
34.98
  • 34.98
AEIR
  • AEIR
UBERON:0002264olfactory bulb
  • UBERON:0000104life cycle
1.46e4
  • 1.46e4
34.65
  • 34.65
AEIR
  • AEIR
UBERON:0016540occipital cortex
  • UBERON:0007222late adult stage
1.46e4
  • 1.46e4
34.52
  • 34.52
AEIR
  • AEIR
UBERON:0000473testis
  • UBERON:0000104life cycle
1.48e4
  • 1.48e4
34.02
  • 34.02
AEIR
  • AEIR
Sources
AAffymetrix
EEST
IIn Situ
RRNA-Seq
data
no data
Rank scores
3.25e4lightgrey: low confidence scores

important score variation

Rank scores of expression calls are normalized across genes, conditions and species. Low score means that the gene is highly expressed in the condition. Max rank score in all species: 4.10e4. Min rank score varies across species.

Expression scores of expression calls use the minimum and maximum Rank of the species to normalize the expression to a value between 0 and 100. Low score means that the gene is lowly expressed in the condition.

Sources of annotations to anatomy and development:
  • RNA-Seq data: Bgee
Sources of raw data:
  • RNA-Seq data: GEO

Orthologs

Taxon nameSpecies with orthologsGene(s)Expression comparisonSee details
Carnivora1 species1 geneCompare expression
Laurasiatheria4 species4 genesCompare expression
Boreoeutheria11 species11 genesCompare expression
Amniota13 species13 genesCompare expression
Euteleostomi14 species14 genesCompare expression

Orthology information comes from OMA : ENSCAFG00000006505.

Cross-references

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