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C. lupus familiaris Gene: APP - ENSCAFG00000008557 - Canis lupus familiaris (dog)

General information

Ensembl IDENSCAFG00000008557
NameAPP
Descriptionamyloid beta (A4) precursor protein [Source:HGNC Symbol;Acc:HGNC:620]
OrganismCanis lupus familiaris (dog)
Synonym(s)abpp, ad1
Orthologs(s)18 orthologs
Paralog(s)1 paralogs

Expression

Anat. entity IDAnatomical entityDevelopmental stage(s)Rank scoreExpression scoreSources
UBERON:0000451prefrontal cortex
  • UBERON:0018241prime adult stage
55.5
  • 55.5
99.76
  • 99.76
AEIR
  • AEIR
UBERON:0016540occipital cortex
  • UBERON:0007222late adult stage
112
  • 112
99.50
  • 99.50
AEIR
  • AEIR
UBERON:0001870frontal cortex
  • UBERON:0007222late adult stage
140
  • 140
99.38
  • 99.38
AEIR
  • AEIR
UBERON:0001255urinary bladder
  • UBERON:0007222late adult stage
146
  • 146
99.35
  • 99.35
AEIR
  • AEIR
UBERON:0002037cerebellum
  • UBERON:0007222late adult stage
  • UBERON:0000104life cycle
163
  • 163
  • 189
99.28
  • 99.28
  • 99.16
AEIR
  • AEIR
  • AEIR
UBERON:0001898hypothalamus
  • UBERON:0000104life cycle
171
  • 171
99.24
  • 99.24
AEIR
  • AEIR
UBERON:0000966retina
  • UBERON:0000104life cycle
178
  • 178
99.21
  • 99.21
AEIR
  • AEIR
UBERON:0001911mammary gland
  • UBERON:0018241prime adult stage
  • UBERON:0000104life cycle
192
  • 192
  • 390
99.15
  • 99.15
  • 98.26
AEIR
  • AEIR
  • AEIR
UBERON:0001871temporal lobe
  • UBERON:0000113post-juvenile adult stage
196
  • 196
99.13
  • 99.13
AEIR
  • AEIR
CL:0000312keratinocyte
  • UBERON:0000104life cycle
224
  • 224
99.00
  • 99.00
AEIR
  • AEIR
UBERON:0000007pituitary gland
  • UBERON:0018241prime adult stage
  • UBERON:0007222late adult stage
225
  • 225
  • 270
99.00
  • 99.00
  • 98.80
AEIR
  • AEIR
  • AEIR
UBERON:0002048lung
  • UBERON:0007222late adult stage
  • UBERON:0000104life cycle
  • UBERON:0000112sexually immature stage
268
  • 268
  • 305
  • 539
98.81
  • 98.81
  • 98.64
  • 97.59
AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0002240spinal cord
  • UBERON:0000104life cycle
270
  • 270
98.80
  • 98.80
AEIR
  • AEIR
UBERON:0002135mitral valve
  • UBERON:0018241prime adult stage
  • UBERON:0007222late adult stage
317
  • 317
  • 411
98.58
  • 98.58
  • 98.17
AEIR
  • AEIR
  • AEIR
UBERON:0000014zone of skin
  • UBERON:0007222late adult stage
  • UBERON:0000104life cycle
327
  • 327
  • 721
98.54
  • 98.54
  • 96.78
AEIR
  • AEIR
  • AEIR
UBERON:0003382cardiac muscle of left ventricle
  • UBERON:0000104life cycle
340
  • 340
98.48
  • 98.48
AEIR
  • AEIR
UBERON:0001013adipose tissue
  • UBERON:0007222late adult stage
349
  • 349
98.44
  • 98.44
AEIR
  • AEIR
UBERON:0000945stomach
  • UBERON:0000113post-juvenile adult stage
  • UBERON:0007222late adult stage
368
  • 368
  • 628
98.36
  • 98.36
  • 97.20
AEIR
  • AEIR
  • AEIR
UBERON:0010533metanephros cortex
  • UBERON:0007222late adult stage
368
  • 368
98.36
  • 98.36
AEIR
  • AEIR
UBERON:0002418cartilage tissue
  • UBERON:0007222late adult stage
373
  • 373
98.34
  • 98.34
AEIR
  • AEIR
UBERON:0002371bone marrow
  • UBERON:0007222late adult stage
388
  • 388
98.27
  • 98.27
AEIR
  • AEIR
UBERON:0000082adult mammalian kidney
  • UBERON:0000112sexually immature stage
  • UBERON:0018241prime adult stage
396
  • 396
  • 426
98.23
  • 98.23
  • 98.10
AEIR
  • AEIR
  • AEIR
UBERON:0002264olfactory bulb
  • UBERON:0000104life cycle
402
  • 402
98.21
  • 98.21
AEIR
  • AEIR
UBERON:0001264pancreas
  • UBERON:0007222late adult stage
  • UBERON:0000104life cycle
  • UBERON:0000113post-juvenile adult stage
406
  • 406
  • 551
  • 660
98.19
  • 98.19
  • 97.54
  • 97.05
AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0002078right cardiac atrium
  • UBERON:0007222late adult stage
414
  • 414
98.15
  • 98.15
AEIR
  • AEIR
UBERON:0002106spleen
  • UBERON:0000104life cycle
  • UBERON:0007222late adult stage
  • UBERON:0000113post-juvenile adult stage
420
  • 420
  • 426
  • 495
98.13
  • 98.13
  • 98.10
  • 97.79
AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0001259mucosa of urinary bladder
  • UBERON:0000104life cycle
433
  • 433
98.07
  • 98.07
AEIR
  • AEIR
UBERON:0000029lymph node
  • UBERON:0007222late adult stage
  • UBERON:0000104life cycle
443
  • 443
  • 2.59e3
98.02
  • 98.02
  • 88.41
AEIR
  • AEIR
  • AEIR
UBERON:0000992female gonad
  • UBERON:0000104life cycle
462
  • 462
97.94
  • 97.94
AEIR
  • AEIR
UBERON:0002084heart left ventricle
  • UBERON:0007222late adult stage
  • UBERON:0018241prime adult stage
530
  • 530
  • 537
97.63
  • 97.63
  • 97.60
AEIR
  • AEIR
  • AEIR
UBERON:0001044saliva-secreting gland
  • UBERON:0007222late adult stage
538
  • 538
97.60
  • 97.60
AEIR
  • AEIR
UBERON:0001155colon
  • UBERON:0000104life cycle
  • UBERON:0007222late adult stage
538
  • 538
  • 608
97.60
  • 97.60
  • 97.29
AEIR
  • AEIR
  • AEIR
UBERON:0002073hair follicle
  • UBERON:0000104life cycle
564
  • 564
97.48
  • 97.48
AEIR
  • AEIR
UBERON:0000948heart
  • UBERON:0000104life cycle
  • UBERON:0000112sexually immature stage
575
  • 575
  • 633
97.43
  • 97.43
  • 97.17
AEIR
  • AEIR
  • AEIR
UBERON:0000362renal medulla
  • UBERON:0007222late adult stage
578
  • 578
97.42
  • 97.42
AEIR
  • AEIR
UBERON:0002108small intestine
  • UBERON:0000113post-juvenile adult stage
  • UBERON:0007222late adult stage
595
  • 595
  • 787
97.34
  • 97.34
  • 96.48
AEIR
  • AEIR
  • AEIR
UBERON:0000059large intestine
  • UBERON:0000113post-juvenile adult stage
596
  • 596
97.34
  • 97.34
AEIR
  • AEIR
UBERON:0000004nose
  • UBERON:0000104life cycle
606
  • 606
97.29
  • 97.29
AEIR
  • AEIR
UBERON:0002080heart right ventricle
  • UBERON:0007222late adult stage
633
  • 633
97.17
  • 97.17
AEIR
  • AEIR
UBERON:0002115jejunum
  • UBERON:0000104life cycle
669
  • 669
97.01
  • 97.01
AEIR
  • AEIR
UBERON:0001235adrenal cortex
  • UBERON:0018241prime adult stage
703
  • 703
96.86
  • 96.86
AEIR
  • AEIR
UBERON:0000033head
  • UBERON:0000112sexually immature stage
731
  • 731
96.73
  • 96.73
AEIR
  • AEIR
UBERON:0002369adrenal gland
  • UBERON:0007222late adult stage
  • UBERON:0000104life cycle
855
  • 855
  • 931
96.18
  • 96.18
  • 95.84
AEIR
  • AEIR
  • AEIR
UBERON:0002107liver
  • UBERON:0000113post-juvenile adult stage
  • UBERON:0018241prime adult stage
  • UBERON:0007222late adult stage
  • UBERON:0000104life cycle
  • UBERON:0000112sexually immature stage
1.11e3
  • 1.11e3
  • 1.27e3
  • 1.58e3
  • 1.71e3
  • 1.88e3
95.03
  • 95.03
  • 94.34
  • 92.94
  • 92.37
  • 91.60
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0001987placenta
  • UBERON:0000113post-juvenile adult stage
1.22e3
  • 1.22e3
94.54
  • 94.54
AEIR
  • AEIR
UBERON:0002370thymus
  • UBERON:0000104life cycle
1.25e3
  • 1.25e3
94.42
  • 94.42
AEIR
  • AEIR
UBERON:0000473testis
  • UBERON:0018241prime adult stage
  • UBERON:0000104life cycle
1.37e3
  • 1.37e3
  • 3.38e3
93.88
  • 93.88
  • 84.89
AEIR
  • AEIR
  • AEIR
UBERON:0002046thyroid gland
  • UBERON:0007222late adult stage
1.44e3
  • 1.44e3
93.58
  • 93.58
AEIR
  • AEIR
UBERON:0001723tongue
  • UBERON:0000113post-juvenile adult stage
1.53e3
  • 1.53e3
93.18
  • 93.18
AEIR
  • AEIR
UBERON:0001135smooth muscle tissue
  • UBERON:0000104life cycle
2.51e3
  • 2.51e3
88.80
  • 88.80
AEIR
  • AEIR
UBERON:0001134skeletal muscle tissue
  • UBERON:0000104life cycle
  • UBERON:0007222late adult stage
2.54e3
  • 2.54e3
  • 3.22e3
88.65
  • 88.65
  • 85.61
AEIR
  • AEIR
  • AEIR
UBERON:0000178blood
  • UBERON:0000104life cycle
4.39e3
  • 4.39e3
80.39
  • 80.39
AEIR
  • AEIR
CL:0000094granulocyte
  • UBERON:0000104life cycle
4.70e3
  • 4.70e3
78.98
  • 78.98
AEIR
  • AEIR
Sources
AAffymetrix
EEST
IIn Situ
RRNA-Seq
data
no data
Rank scores
3.25e4lightgrey: low confidence scores

important score variation

Rank scores of expression calls are normalized across genes, conditions and species. Low score means that the gene is highly expressed in the condition. Max rank score in all species: 4.10e4. Min rank score varies across species.

Expression scores of expression calls use the minimum and maximum Rank of the species to normalize the expression to a value between 0 and 100. Low score means that the gene is lowly expressed in the condition.

Sources of annotations to anatomy and development:
  • RNA-Seq data: Bgee
Sources of raw data:
  • RNA-Seq data: GEO

Orthologs

Taxon nameSpecies with orthologsGene(s)Expression comparisonSee details
Carnivora1 species1 geneCompare expression
Laurasiatheria5 species5 genesCompare expression
Boreoeutheria13 species13 genesCompare expression
Theria14 species14 genesCompare expression
Amniota16 species16 genesCompare expression
Tetrapoda17 species17 genesCompare expression
Euteleostomi18 species18 genesCompare expression

Orthology information comes from OMA : ENSCAFG00000008557.

Paralogs (same species)

Taxon nameGene(s)Expression comparisonSee details
Deuterostomia1 geneCompare expression

Paralogy information comes from OMA : ENSCAFG00000008557.

Cross-references

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