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C. lupus familiaris Gene: MTHFD2 - ENSCAFG00000008716 - Canis lupus familiaris (dog)

General information

Ensembl IDENSCAFG00000008716
NameMTHFD2
DescriptionUncharacterized protein [Source:UniProtKB/TrEMBL;Acc:E2RQ65]
OrganismCanis lupus familiaris (dog)
Orthologs(s)22 orthologs
Paralog(s)2 paralogs

Expression

Anat. entity IDAnatomical entityDevelopmental stage(s)Rank scoreExpression scoreSources
CL:0000312keratinocyte
  • UBERON:0000104life cycle
1.41e3
  • 1.41e3
93.69
  • 93.69
AEIR
  • AEIR
UBERON:0001264pancreas
  • UBERON:0000113post-juvenile adult stage
  • UBERON:0000104life cycle
  • UBERON:0007222late adult stage
1.73e3
  • 1.73e3
  • 4.03e3
  • 7.84e3
92.25
  • 92.25
  • 81.97
  • 64.93
AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0000948heart
  • UBERON:0000112sexually immature stage
  • UBERON:0000104life cycle
2.19e3
  • 2.19e3
  • 1.41e4
90.21
  • 90.21
  • 37.00
AEIR
  • AEIR
  • AEIR
UBERON:0002048lung
  • UBERON:0000112sexually immature stage
  • UBERON:0007222late adult stage
  • UBERON:0000104life cycle
2.85e3
  • 2.85e3
  • 1.07e4
  • 1.09e4
87.28
  • 87.28
  • 51.93
  • 51.25
AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0000033head
  • UBERON:0000112sexually immature stage
3.22e3
  • 3.22e3
85.60
  • 85.60
AEIR
  • AEIR
UBERON:0002418cartilage tissue
  • UBERON:0007222late adult stage
3.34e3
  • 3.34e3
85.06
  • 85.06
AEIR
  • AEIR
UBERON:0000082adult mammalian kidney
  • UBERON:0000112sexually immature stage
  • UBERON:0018241prime adult stage
3.45e3
  • 3.45e3
  • 1.46e4
84.59
  • 84.59
  • 34.88
AEIR
  • AEIR
  • AEIR
UBERON:0002369adrenal gland
  • UBERON:0000104life cycle
  • UBERON:0007222late adult stage
3.94e3
  • 3.94e3
  • 6.57e3
82.40
  • 82.40
  • 70.63
AEIR
  • AEIR
  • AEIR
UBERON:0000473testis
  • UBERON:0000104life cycle
4.23e3
  • 4.23e3
81.09
  • 81.09
AEIR
  • AEIR
UBERON:0000992female gonad
  • UBERON:0000104life cycle
5.28e3
  • 5.28e3
76.40
  • 76.40
AEIR
  • AEIR
UBERON:0002108small intestine
  • UBERON:0007222late adult stage
  • UBERON:0000113post-juvenile adult stage
6.16e3
  • 6.16e3
  • 8.92e3
72.48
  • 72.48
  • 60.10
AEIR
  • AEIR
  • AEIR
UBERON:0002106spleen
  • UBERON:0000113post-juvenile adult stage
  • UBERON:0007222late adult stage
  • UBERON:0000104life cycle
6.90e3
  • 6.90e3
  • 8.57e3
  • 1.09e4
69.15
  • 69.15
  • 61.68
  • 51.21
AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0000945stomach
  • UBERON:0007222late adult stage
  • UBERON:0000113post-juvenile adult stage
6.91e3
  • 6.91e3
  • 7.12e3
69.09
  • 69.09
  • 68.17
AEIR
  • AEIR
  • AEIR
UBERON:0001235adrenal cortex
  • UBERON:0018241prime adult stage
7.33e3
  • 7.33e3
67.24
  • 67.24
AEIR
  • AEIR
UBERON:0002037cerebellum
  • UBERON:0000104life cycle
  • UBERON:0007222late adult stage
7.36e3
  • 7.36e3
  • 7.54e3
67.08
  • 67.08
  • 66.30
AEIR
  • AEIR
  • AEIR
UBERON:0000029lymph node
  • UBERON:0000104life cycle
  • UBERON:0007222late adult stage
7.38e3
  • 7.38e3
  • 9.08e3
67.01
  • 67.01
  • 59.39
AEIR
  • AEIR
  • AEIR
UBERON:0000178blood
  • UBERON:0000104life cycle
7.70e3
  • 7.70e3
65.55
  • 65.55
AEIR
  • AEIR
UBERON:0001155colon
  • UBERON:0007222late adult stage
  • UBERON:0000104life cycle
7.76e3
  • 7.76e3
  • 1.03e4
65.31
  • 65.31
  • 54.01
AEIR
  • AEIR
  • AEIR
UBERON:0002107liver
  • UBERON:0000112sexually immature stage
  • UBERON:0000113post-juvenile adult stage
  • UBERON:0007222late adult stage
  • UBERON:0018241prime adult stage
  • UBERON:0000104life cycle
7.78e3
  • 7.78e3
  • 1.26e4
  • 1.26e4
  • 1.53e4
  • 1.59e4
65.22
  • 65.22
  • 43.85
  • 43.59
  • 31.65
  • 28.78
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0000007pituitary gland
  • UBERON:0007222late adult stage
  • UBERON:0018241prime adult stage
7.88e3
  • 7.88e3
  • 8.91e3
64.75
  • 64.75
  • 60.14
AEIR
  • AEIR
  • AEIR
UBERON:0002240spinal cord
  • UBERON:0000104life cycle
7.89e3
  • 7.89e3
64.72
  • 64.72
AEIR
  • AEIR
UBERON:0001898hypothalamus
  • UBERON:0000104life cycle
7.97e3
  • 7.97e3
64.36
  • 64.36
AEIR
  • AEIR
UBERON:0002370thymus
  • UBERON:0000104life cycle
8.24e3
  • 8.24e3
63.15
  • 63.15
AEIR
  • AEIR
UBERON:0002135mitral valve
  • UBERON:0007222late adult stage
  • UBERON:0018241prime adult stage
8.75e3
  • 8.75e3
  • 9.86e3
60.88
  • 60.88
  • 55.91
AEIR
  • AEIR
  • AEIR
UBERON:0002021occipital lobe
  • UBERON:0000113post-juvenile adult stage
8.80e3
  • 8.80e3
60.66
  • 60.66
AEIR
  • AEIR
UBERON:0000004nose
  • UBERON:0000104life cycle
8.81e3
  • 8.81e3
60.63
  • 60.63
AEIR
  • AEIR
UBERON:0001044saliva-secreting gland
  • UBERON:0007222late adult stage
9.07e3
  • 9.07e3
59.43
  • 59.43
AEIR
  • AEIR
UBERON:0001135smooth muscle tissue
  • UBERON:0000104life cycle
9.08e3
  • 9.08e3
59.40
  • 59.40
AEIR
  • AEIR
UBERON:0001134skeletal muscle tissue
  • UBERON:0000104life cycle
  • UBERON:0007222late adult stage
9.10e3
  • 9.10e3
  • 1.06e4
59.33
  • 59.33
  • 52.46
AEIR
  • AEIR
  • AEIR
UBERON:0002084heart left ventricle
  • UBERON:0007222late adult stage
  • UBERON:0018241prime adult stage
9.21e3
  • 9.21e3
  • 1.17e4
58.81
  • 58.81
  • 47.86
AEIR
  • AEIR
  • AEIR
UBERON:0001255urinary bladder
  • UBERON:0007222late adult stage
9.23e3
  • 9.23e3
58.75
  • 58.75
AEIR
  • AEIR
UBERON:0002264olfactory bulb
  • UBERON:0000104life cycle
9.46e3
  • 9.46e3
57.70
  • 57.70
AEIR
  • AEIR
UBERON:0000966retina
  • UBERON:0000104life cycle
9.52e3
  • 9.52e3
57.42
  • 57.42
AEIR
  • AEIR
UBERON:0002078right cardiac atrium
  • UBERON:0007222late adult stage
9.75e3
  • 9.75e3
56.41
  • 56.41
AEIR
  • AEIR
UBERON:0001259mucosa of urinary bladder
  • UBERON:0000104life cycle
9.78e3
  • 9.78e3
56.28
  • 56.28
AEIR
  • AEIR
UBERON:0001871temporal lobe
  • UBERON:0000113post-juvenile adult stage
9.92e3
  • 9.92e3
55.65
  • 55.65
AEIR
  • AEIR
UBERON:0016540occipital cortex
  • UBERON:0007222late adult stage
9.97e3
  • 9.97e3
55.43
  • 55.43
AEIR
  • AEIR
UBERON:0001987placenta
  • UBERON:0000113post-juvenile adult stage
9.99e3
  • 9.99e3
55.32
  • 55.32
AEIR
  • AEIR
UBERON:0002115jejunum
  • UBERON:0000104life cycle
1.00e4
  • 1.00e4
55.14
  • 55.14
AEIR
  • AEIR
UBERON:0001723tongue
  • UBERON:0000113post-juvenile adult stage
1.01e4
  • 1.01e4
54.78
  • 54.78
AEIR
  • AEIR
UBERON:0001911mammary gland
  • UBERON:0018241prime adult stage
  • UBERON:0000104life cycle
1.03e4
  • 1.03e4
  • 1.17e4
54.03
  • 54.03
  • 47.76
AEIR
  • AEIR
  • AEIR
UBERON:0002371bone marrow
  • UBERON:0007222late adult stage
1.06e4
  • 1.06e4
52.39
  • 52.39
AEIR
  • AEIR
UBERON:0001013adipose tissue
  • UBERON:0007222late adult stage
1.07e4
  • 1.07e4
52.16
  • 52.16
AEIR
  • AEIR
UBERON:0000014zone of skin
  • UBERON:0007222late adult stage
  • UBERON:0000104life cycle
1.07e4
  • 1.07e4
  • 1.20e4
51.97
  • 51.97
  • 46.47
AEIR
  • AEIR
  • AEIR
UBERON:0000451prefrontal cortex
  • UBERON:0018241prime adult stage
1.07e4
  • 1.07e4
51.95
  • 51.95
AEIR
  • AEIR
UBERON:0003382cardiac muscle of left ventricle
  • UBERON:0000104life cycle
1.08e4
  • 1.08e4
51.80
  • 51.80
AEIR
  • AEIR
UBERON:0002080heart right ventricle
  • UBERON:0007222late adult stage
1.10e4
  • 1.10e4
50.63
  • 50.63
AEIR
  • AEIR
UBERON:0001870frontal cortex
  • UBERON:0007222late adult stage
1.15e4
  • 1.15e4
48.50
  • 48.50
AEIR
  • AEIR
UBERON:0002046thyroid gland
  • UBERON:0007222late adult stage
1.25e4
  • 1.25e4
44.23
  • 44.23
AEIR
  • AEIR
UBERON:0002073hair follicle
  • UBERON:0000104life cycle
1.25e4
  • 1.25e4
43.96
  • 43.96
AEIR
  • AEIR
UBERON:0000362renal medulla
  • UBERON:0007222late adult stage
1.27e4
  • 1.27e4
43.42
  • 43.42
AEIR
  • AEIR
UBERON:0010533metanephros cortex
  • UBERON:0007222late adult stage
1.27e4
  • 1.27e4
43.22
  • 43.22
AEIR
  • AEIR
Sources
AAffymetrix
EEST
IIn Situ
RRNA-Seq
data
no data
Rank scores
3.25e4lightgrey: low confidence scores

important score variation

Rank scores of expression calls are normalized across genes, conditions and species. Low score means that the gene is highly expressed in the condition. Max rank score in all species: 4.10e4. Min rank score varies across species.

Expression scores of expression calls use the minimum and maximum Rank of the species to normalize the expression to a value between 0 and 100. Low score means that the gene is lowly expressed in the condition.

Sources of annotations to anatomy and development:
  • RNA-Seq data: Bgee
Sources of raw data:
  • RNA-Seq data: GEO

Orthologs

Taxon nameSpecies with orthologsGene(s)Expression comparisonSee details
Carnivora1 species1 geneCompare expression
Laurasiatheria5 species5 genesCompare expression
Boreoeutheria12 species12 genesCompare expression
Amniota14 species14 genesCompare expression
Tetrapoda15 species15 genesCompare expression
Euteleostomi16 species16 genesCompare expression
Bilateria22 species22 genesCompare expression

Orthology information comes from OMA : ENSCAFG00000008716.

Paralogs (same species)

Taxon nameGene(s)Expression comparisonSee details
Deuterostomia1 geneCompare expression
Eukaryota2 genesCompare expression

Paralogy information comes from OMA : ENSCAFG00000008716.

Cross-references

EnsemblENSCAFG00000008716 (MTHFD2)
HGNCHGNC:7434 (MTHFD2)
EMBLAAEX03010965
Uniprot/SPTREMBLE2RQ65, E2RQ65_CANLF

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