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C. lupus familiaris Gene: SIRT4 - ENSCAFG00000010258 - Canis lupus familiaris (dog)

General information

Ensembl IDENSCAFG00000010258
NameSIRT4
Descriptionsirtuin 4 [Source:HGNC Symbol;Acc:HGNC:14932]
OrganismCanis lupus familiaris (dog)
Synonym(s)sir2l4
Orthologs(s)24 orthologs
Paralog(s)5 paralogs

Expression

Anat. entity IDAnatomical entityDevelopmental stage(s)Rank scoreExpression scoreSources
UBERON:0001134skeletal muscle tissue
  • UBERON:0007222late adult stage
  • UBERON:0000104life cycle
5.79e3
  • 5.79e3
  • 8.76e3
74.11
  • 74.11
  • 60.82
AEIR
  • AEIR
  • AEIR
UBERON:0001264pancreas
  • UBERON:0007222late adult stage
  • UBERON:0000104life cycle
  • UBERON:0000113post-juvenile adult stage
5.96e3
  • 5.96e3
  • 6.13e3
  • 7.81e3
73.36
  • 73.36
  • 72.58
  • 65.08
AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0002107liver
  • UBERON:0007222late adult stage
  • UBERON:0000104life cycle
  • UBERON:0018241prime adult stage
  • UBERON:0000112sexually immature stage
  • UBERON:0000113post-juvenile adult stage
6.16e3
  • 6.16e3
  • 8.59e3
  • 8.65e3
  • 8.78e3
  • 9.08e3
72.44
  • 72.44
  • 61.58
  • 61.33
  • 60.74
  • 59.39
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0002037cerebellum
  • UBERON:0007222late adult stage
  • UBERON:0000104life cycle
6.35e3
  • 6.35e3
  • 8.88e3
71.60
  • 71.60
  • 60.28
AEIR
  • AEIR
  • AEIR
UBERON:0002084heart left ventricle
  • UBERON:0018241prime adult stage
  • UBERON:0007222late adult stage
7.02e3
  • 7.02e3
  • 8.98e3
68.62
  • 68.62
  • 59.85
AEIR
  • AEIR
  • AEIR
UBERON:0002046thyroid gland
  • UBERON:0007222late adult stage
7.34e3
  • 7.34e3
67.17
  • 67.17
AEIR
  • AEIR
UBERON:0000362renal medulla
  • UBERON:0007222late adult stage
7.61e3
  • 7.61e3
65.98
  • 65.98
AEIR
  • AEIR
UBERON:0002080heart right ventricle
  • UBERON:0007222late adult stage
7.64e3
  • 7.64e3
65.83
  • 65.83
AEIR
  • AEIR
UBERON:0000945stomach
  • UBERON:0000113post-juvenile adult stage
  • UBERON:0007222late adult stage
7.68e3
  • 7.68e3
  • 9.61e3
65.67
  • 65.67
  • 57.01
AEIR
  • AEIR
  • AEIR
UBERON:0002369adrenal gland
  • UBERON:0007222late adult stage
  • UBERON:0000104life cycle
7.85e3
  • 7.85e3
  • 8.79e3
64.91
  • 64.91
  • 60.72
AEIR
  • AEIR
  • AEIR
UBERON:0001255urinary bladder
  • UBERON:0007222late adult stage
7.88e3
  • 7.88e3
64.76
  • 64.76
AEIR
  • AEIR
UBERON:0001044saliva-secreting gland
  • UBERON:0007222late adult stage
7.89e3
  • 7.89e3
64.72
  • 64.72
AEIR
  • AEIR
UBERON:0001723tongue
  • UBERON:0000113post-juvenile adult stage
7.92e3
  • 7.92e3
64.61
  • 64.61
AEIR
  • AEIR
UBERON:0001235adrenal cortex
  • UBERON:0018241prime adult stage
7.94e3
  • 7.94e3
64.51
  • 64.51
AEIR
  • AEIR
UBERON:0002079left cardiac atrium
  • UBERON:0007222late adult stage
8.13e3
  • 8.13e3
63.64
  • 63.64
AEIR
  • AEIR
UBERON:0000007pituitary gland
  • UBERON:0007222late adult stage
  • UBERON:0018241prime adult stage
8.26e3
  • 8.26e3
  • 8.51e3
63.07
  • 63.07
  • 61.97
AEIR
  • AEIR
  • AEIR
UBERON:0002078right cardiac atrium
  • UBERON:0007222late adult stage
8.28e3
  • 8.28e3
62.97
  • 62.97
AEIR
  • AEIR
UBERON:0002108small intestine
  • UBERON:0007222late adult stage
  • UBERON:0000113post-juvenile adult stage
8.43e3
  • 8.43e3
  • 9.38e3
62.32
  • 62.32
  • 58.04
AEIR
  • AEIR
  • AEIR
UBERON:0016540occipital cortex
  • UBERON:0007222late adult stage
8.43e3
  • 8.43e3
62.30
  • 62.30
AEIR
  • AEIR
UBERON:0001898hypothalamus
  • UBERON:0000104life cycle
8.51e3
  • 8.51e3
61.97
  • 61.97
AEIR
  • AEIR
UBERON:0003382cardiac muscle of left ventricle
  • UBERON:0000104life cycle
8.58e3
  • 8.58e3
61.63
  • 61.63
AEIR
  • AEIR
UBERON:0000059large intestine
  • UBERON:0000113post-juvenile adult stage
8.67e3
  • 8.67e3
61.25
  • 61.25
AEIR
  • AEIR
UBERON:0001135smooth muscle tissue
  • UBERON:0000104life cycle
8.73e3
  • 8.73e3
60.95
  • 60.95
AEIR
  • AEIR
UBERON:0002418cartilage tissue
  • UBERON:0007222late adult stage
8.77e3
  • 8.77e3
60.80
  • 60.80
AEIR
  • AEIR
UBERON:0002135mitral valve
  • UBERON:0018241prime adult stage
  • UBERON:0007222late adult stage
8.79e3
  • 8.79e3
  • 9.72e3
60.68
  • 60.68
  • 56.54
AEIR
  • AEIR
  • AEIR
CL:0000094granulocyte
  • UBERON:0000104life cycle
8.81e3
  • 8.81e3
60.61
  • 60.61
AEIR
  • AEIR
UBERON:0002371bone marrow
  • UBERON:0007222late adult stage
8.88e3
  • 8.88e3
60.31
  • 60.31
AEIR
  • AEIR
UBERON:0010533metanephros cortex
  • UBERON:0007222late adult stage
8.93e3
  • 8.93e3
60.07
  • 60.07
AEIR
  • AEIR
UBERON:0000948heart
  • UBERON:0000104life cycle
  • UBERON:0000112sexually immature stage
9.01e3
  • 9.01e3
  • 9.66e3
59.72
  • 59.72
  • 56.80
AEIR
  • AEIR
  • AEIR
UBERON:0001013adipose tissue
  • UBERON:0007222late adult stage
9.07e3
  • 9.07e3
59.42
  • 59.42
AEIR
  • AEIR
UBERON:0000014zone of skin
  • UBERON:0007222late adult stage
  • UBERON:0000104life cycle
9.15e3
  • 9.15e3
  • 1.17e4
59.09
  • 59.09
  • 47.53
AEIR
  • AEIR
  • AEIR
UBERON:0001155colon
  • UBERON:0007222late adult stage
  • UBERON:0000104life cycle
9.15e3
  • 9.15e3
  • 9.87e3
59.08
  • 59.08
  • 55.85
AEIR
  • AEIR
  • AEIR
UBERON:0000029lymph node
  • UBERON:0007222late adult stage
  • UBERON:0000104life cycle
9.20e3
  • 9.20e3
  • 1.01e4
58.87
  • 58.87
  • 54.81
AEIR
  • AEIR
  • AEIR
UBERON:0002048lung
  • UBERON:0000112sexually immature stage
  • UBERON:0007222late adult stage
  • UBERON:0000104life cycle
9.21e3
  • 9.21e3
  • 1.04e4
  • 1.20e4
58.81
  • 58.81
  • 53.71
  • 46.47
AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0001987placenta
  • UBERON:0000113post-juvenile adult stage
9.28e3
  • 9.28e3
58.49
  • 58.49
AEIR
  • AEIR
UBERON:0001911mammary gland
  • UBERON:0000104life cycle
  • UBERON:0018241prime adult stage
9.43e3
  • 9.43e3
  • 1.04e4
57.85
  • 57.85
  • 53.32
AEIR
  • AEIR
  • AEIR
UBERON:0002106spleen
  • UBERON:0007222late adult stage
  • UBERON:0000104life cycle
  • UBERON:0000113post-juvenile adult stage
9.44e3
  • 9.44e3
  • 9.92e3
  • 1.05e4
57.81
  • 57.81
  • 55.62
  • 53.13
AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0001871temporal lobe
  • UBERON:0000113post-juvenile adult stage
9.47e3
  • 9.47e3
57.65
  • 57.65
AEIR
  • AEIR
UBERON:0000004nose
  • UBERON:0000104life cycle
9.48e3
  • 9.48e3
57.60
  • 57.60
AEIR
  • AEIR
UBERON:0002073hair follicle
  • UBERON:0000104life cycle
9.56e3
  • 9.56e3
57.26
  • 57.26
AEIR
  • AEIR
UBERON:0000082adult mammalian kidney
  • UBERON:0000112sexually immature stage
  • UBERON:0018241prime adult stage
9.63e3
  • 9.63e3
  • 9.66e3
56.96
  • 56.96
  • 56.78
AEIR
  • AEIR
  • AEIR
UBERON:0001259mucosa of urinary bladder
  • UBERON:0000104life cycle
9.66e3
  • 9.66e3
56.79
  • 56.79
AEIR
  • AEIR
UBERON:0000992female gonad
  • UBERON:0000104life cycle
9.77e3
  • 9.77e3
56.33
  • 56.33
AEIR
  • AEIR
UBERON:0001870frontal cortex
  • UBERON:0007222late adult stage
9.86e3
  • 9.86e3
55.89
  • 55.89
AEIR
  • AEIR
UBERON:0002264olfactory bulb
  • UBERON:0000104life cycle
9.87e3
  • 9.87e3
55.87
  • 55.87
AEIR
  • AEIR
UBERON:0000178blood
  • UBERON:0000104life cycle
9.91e3
  • 9.91e3
55.67
  • 55.67
AEIR
  • AEIR
UBERON:0002370thymus
  • UBERON:0000104life cycle
9.95e3
  • 9.95e3
55.50
  • 55.50
AEIR
  • AEIR
UBERON:0000033head
  • UBERON:0000112sexually immature stage
1.01e4
  • 1.01e4
54.99
  • 54.99
AEIR
  • AEIR
CL:0000312keratinocyte
  • UBERON:0000104life cycle
1.01e4
  • 1.01e4
54.87
  • 54.87
AEIR
  • AEIR
UBERON:0002115jejunum
  • UBERON:0000104life cycle
1.02e4
  • 1.02e4
54.42
  • 54.42
AEIR
  • AEIR
UBERON:0000966retina
  • UBERON:0000104life cycle
1.07e4
  • 1.07e4
52.13
  • 52.13
AEIR
  • AEIR
UBERON:0002240spinal cord
  • UBERON:0000104life cycle
1.11e4
  • 1.11e4
50.52
  • 50.52
AEIR
  • AEIR
UBERON:0000451prefrontal cortex
  • UBERON:0018241prime adult stage
1.19e4
  • 1.19e4
46.65
  • 46.65
AEIR
  • AEIR
UBERON:0000473testis
  • UBERON:0000104life cycle
1.26e4
  • 1.26e4
43.52
  • 43.52
AEIR
  • AEIR
Sources
AAffymetrix
EEST
IIn Situ
RRNA-Seq
data
no data
Rank scores
3.25e4lightgrey: low confidence scores

important score variation

Rank scores of expression calls are normalized across genes, conditions and species. Low score means that the gene is highly expressed in the condition. Max rank score in all species: 4.10e4. Min rank score varies across species.

Expression scores of expression calls use the minimum and maximum Rank of the species to normalize the expression to a value between 0 and 100. Low score means that the gene is lowly expressed in the condition.

Sources of annotations to anatomy and development:
  • RNA-Seq data: Bgee
Sources of raw data:
  • RNA-Seq data: GEO

Orthologs

Taxon nameSpecies with orthologsGene(s)Expression comparisonSee details
Carnivora1 species1 geneCompare expression
Laurasiatheria4 species4 genesCompare expression
Boreoeutheria11 species11 genesCompare expression
Mammalia12 species12 genesCompare expression
Amniota14 species14 genesCompare expression
Tetrapoda15 species15 genesCompare expression
Euteleostomi16 species16 genesCompare expression
Bilateria23 species24 genesCompare expression

Orthology information comes from OMA : ENSCAFG00000010258.

Paralogs (same species)

Taxon nameGene(s)Expression comparisonSee details
Eukaryota5 genesCompare expression

Paralogy information comes from OMA : ENSCAFG00000010258.

Cross-references

EnsemblENSCAFG00000010258 (SIRT4)
HGNCHGNC:14932 (SIRT4)
EMBLAAEX03014734
Uniprot/SPTREMBLF1PU57, F1PU57_CANLF

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