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C. lupus familiaris Gene: NGEF - ENSCAFG00000011587 - Canis lupus familiaris (dog)

General information

Ensembl IDENSCAFG00000011587
NameNGEF
Descriptionneuronal guanine nucleotide exchange factor [Source:HGNC Symbol;Acc:HGNC:7807]
OrganismCanis lupus familiaris (dog)
Synonym(s)arhgef27
Orthologs(s)18 orthologs

Expression

Anat. entity IDAnatomical entityDevelopmental stage(s)Rank scoreExpression scoreSources
UBERON:0002418cartilage tissue
  • UBERON:0007222late adult stage
875
  • 875
96.09
  • 96.09
AEIR
  • AEIR
UBERON:0000451prefrontal cortex
  • UBERON:0018241prime adult stage
1.16e3
  • 1.16e3
94.82
  • 94.82
AEIR
  • AEIR
UBERON:0002021occipital lobe
  • UBERON:0000113post-juvenile adult stage
1.23e3
  • 1.23e3
94.48
  • 94.48
AEIR
  • AEIR
UBERON:0001870frontal cortex
  • UBERON:0007222late adult stage
1.49e3
  • 1.49e3
93.35
  • 93.35
AEIR
  • AEIR
UBERON:0001871temporal lobe
  • UBERON:0000113post-juvenile adult stage
1.51e3
  • 1.51e3
93.27
  • 93.27
AEIR
  • AEIR
UBERON:0016540occipital cortex
  • UBERON:0007222late adult stage
1.76e3
  • 1.76e3
92.15
  • 92.15
AEIR
  • AEIR
CL:0000312keratinocyte
  • UBERON:0000104life cycle
2.70e3
  • 2.70e3
87.94
  • 87.94
AEIR
  • AEIR
UBERON:0000004nose
  • UBERON:0000104life cycle
3.28e3
  • 3.28e3
85.35
  • 85.35
AEIR
  • AEIR
UBERON:0001264pancreas
  • UBERON:0000113post-juvenile adult stage
  • UBERON:0000104life cycle
  • UBERON:0007222late adult stage
4.22e3
  • 4.22e3
  • 6.19e3
  • 6.74e3
81.13
  • 81.13
  • 72.34
  • 69.85
AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0001911mammary gland
  • UBERON:0000104life cycle
  • UBERON:0018241prime adult stage
4.68e3
  • 4.68e3
  • 1.31e4
79.07
  • 79.07
  • 41.24
AEIR
  • AEIR
  • AEIR
UBERON:0002107liver
  • UBERON:0000104life cycle
  • UBERON:0000113post-juvenile adult stage
  • UBERON:0007222late adult stage
  • UBERON:0018241prime adult stage
  • UBERON:0000112sexually immature stage
4.78e3
  • 4.78e3
  • 5.74e3
  • 6.74e3
  • 6.74e3
  • 1.07e4
78.64
  • 78.64
  • 74.33
  • 69.89
  • 69.87
  • 52.03
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0002113kidney
  • UBERON:0000104life cycle
4.90e3
  • 4.90e3
78.08
  • 78.08
AEIR
  • AEIR
UBERON:0002073hair follicle
  • UBERON:0000104life cycle
5.31e3
  • 5.31e3
76.24
  • 76.24
AEIR
  • AEIR
UBERON:0002264olfactory bulb
  • UBERON:0000104life cycle
5.41e3
  • 5.41e3
75.81
  • 75.81
AEIR
  • AEIR
UBERON:0000059large intestine
  • UBERON:0000113post-juvenile adult stage
5.85e3
  • 5.85e3
73.84
  • 73.84
AEIR
  • AEIR
UBERON:0002115jejunum
  • UBERON:0000104life cycle
6.14e3
  • 6.14e3
72.53
  • 72.53
AEIR
  • AEIR
UBERON:0002108small intestine
  • UBERON:0000113post-juvenile adult stage
  • UBERON:0007222late adult stage
6.16e3
  • 6.16e3
  • 1.16e4
72.44
  • 72.44
  • 48.00
AEIR
  • AEIR
  • AEIR
UBERON:0000082adult mammalian kidney
  • UBERON:0018241prime adult stage
  • UBERON:0000112sexually immature stage
6.18e3
  • 6.18e3
  • 1.45e4
72.38
  • 72.38
  • 35.27
AEIR
  • AEIR
  • AEIR
UBERON:0000014zone of skin
  • UBERON:0000104life cycle
  • UBERON:0007222late adult stage
6.18e3
  • 6.18e3
  • 1.26e4
72.35
  • 72.35
  • 43.57
AEIR
  • AEIR
  • AEIR
UBERON:0000362renal medulla
  • UBERON:0007222late adult stage
6.86e3
  • 6.86e3
69.33
  • 69.33
AEIR
  • AEIR
UBERON:0001155colon
  • UBERON:0000104life cycle
  • UBERON:0007222late adult stage
7.13e3
  • 7.13e3
  • 1.35e4
68.11
  • 68.11
  • 39.83
AEIR
  • AEIR
  • AEIR
UBERON:0010533metanephros cortex
  • UBERON:0007222late adult stage
7.43e3
  • 7.43e3
66.79
  • 66.79
AEIR
  • AEIR
UBERON:0003382cardiac muscle of left ventricle
  • UBERON:0000104life cycle
7.56e3
  • 7.56e3
66.21
  • 66.21
AEIR
  • AEIR
UBERON:0000945stomach
  • UBERON:0000113post-juvenile adult stage
  • UBERON:0007222late adult stage
7.73e3
  • 7.73e3
  • 1.33e4
65.44
  • 65.44
  • 40.42
AEIR
  • AEIR
  • AEIR
UBERON:0000948heart
  • UBERON:0000104life cycle
  • UBERON:0000112sexually immature stage
7.92e3
  • 7.92e3
  • 1.20e4
64.61
  • 64.61
  • 46.25
AEIR
  • AEIR
  • AEIR
UBERON:0001898hypothalamus
  • UBERON:0000104life cycle
8.36e3
  • 8.36e3
62.61
  • 62.61
AEIR
  • AEIR
UBERON:0002084heart left ventricle
  • UBERON:0018241prime adult stage
  • UBERON:0007222late adult stage
8.79e3
  • 8.79e3
  • 9.49e3
60.70
  • 60.70
  • 57.57
AEIR
  • AEIR
  • AEIR
UBERON:0002080heart right ventricle
  • UBERON:0007222late adult stage
8.83e3
  • 8.83e3
60.54
  • 60.54
AEIR
  • AEIR
UBERON:0000966retina
  • UBERON:0000104life cycle
9.56e3
  • 9.56e3
57.25
  • 57.25
AEIR
  • AEIR
UBERON:0002046thyroid gland
  • UBERON:0007222late adult stage
9.83e3
  • 9.83e3
56.04
  • 56.04
AEIR
  • AEIR
UBERON:0002240spinal cord
  • UBERON:0000104life cycle
1.03e4
  • 1.03e4
54.09
  • 54.09
AEIR
  • AEIR
UBERON:0002135mitral valve
  • UBERON:0018241prime adult stage
  • UBERON:0007222late adult stage
1.05e4
  • 1.05e4
  • 1.15e4
53.12
  • 53.12
  • 48.79
AEIR
  • AEIR
  • AEIR
UBERON:0001044saliva-secreting gland
  • UBERON:0007222late adult stage
1.08e4
  • 1.08e4
51.83
  • 51.83
AEIR
  • AEIR
UBERON:0002369adrenal gland
  • UBERON:0000104life cycle
  • UBERON:0007222late adult stage
1.11e4
  • 1.11e4
  • 1.30e4
50.50
  • 50.50
  • 41.92
AEIR
  • AEIR
  • AEIR
UBERON:0000473testis
  • UBERON:0000104life cycle
1.11e4
  • 1.11e4
50.39
  • 50.39
AEIR
  • AEIR
UBERON:0001723tongue
  • UBERON:0000113post-juvenile adult stage
1.13e4
  • 1.13e4
49.30
  • 49.30
AEIR
  • AEIR
UBERON:0001259mucosa of urinary bladder
  • UBERON:0000104life cycle
1.15e4
  • 1.15e4
48.45
  • 48.45
AEIR
  • AEIR
UBERON:0002037cerebellum
  • UBERON:0007222late adult stage
  • UBERON:0000104life cycle
1.16e4
  • 1.16e4
  • 1.20e4
48.28
  • 48.28
  • 46.43
AEIR
  • AEIR
  • AEIR
UBERON:0002106spleen
  • UBERON:0000113post-juvenile adult stage
  • UBERON:0000104life cycle
  • UBERON:0007222late adult stage
1.25e4
  • 1.25e4
  • 1.28e4
  • 1.35e4
44.30
  • 44.30
  • 42.65
  • 39.59
AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0002048lung
  • UBERON:0007222late adult stage
  • UBERON:0000104life cycle
  • UBERON:0000112sexually immature stage
1.26e4
  • 1.26e4
  • 1.37e4
  • 1.58e4
43.75
  • 43.75
  • 38.87
  • 29.25
AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0000029lymph node
  • UBERON:0000104life cycle
  • UBERON:0007222late adult stage
1.27e4
  • 1.27e4
  • 1.37e4
43.43
  • 43.43
  • 38.84
AEIR
  • AEIR
  • AEIR
UBERON:0000033head
  • UBERON:0000112sexually immature stage
1.27e4
  • 1.27e4
43.11
  • 43.11
AEIR
  • AEIR
UBERON:0002370thymus
  • UBERON:0000104life cycle
1.28e4
  • 1.28e4
42.61
  • 42.61
AEIR
  • AEIR
UBERON:0000007pituitary gland
  • UBERON:0007222late adult stage
  • UBERON:0018241prime adult stage
1.36e4
  • 1.36e4
  • 1.43e4
39.02
  • 39.02
  • 36.10
AEIR
  • AEIR
  • AEIR
UBERON:0002078right cardiac atrium
  • UBERON:0007222late adult stage
1.44e4
  • 1.44e4
35.65
  • 35.65
AEIR
  • AEIR
UBERON:0001134skeletal muscle tissue
  • UBERON:0007222late adult stage
  • UBERON:0000104life cycle
1.45e4
  • 1.45e4
  • 1.49e4
35.28
  • 35.28
  • 33.25
AEIR
  • AEIR
  • AEIR
UBERON:0001235adrenal cortex
  • UBERON:0018241prime adult stage
1.47e4
  • 1.47e4
34.26
  • 34.26
AEIR
  • AEIR
UBERON:0001135smooth muscle tissue
  • UBERON:0000104life cycle
1.49e4
  • 1.49e4
33.29
  • 33.29
AEIR
  • AEIR
UBERON:0001013adipose tissue
  • UBERON:0007222late adult stage
1.50e4
  • 1.50e4
32.91
  • 32.91
AEIR
  • AEIR
UBERON:0001255urinary bladder
  • UBERON:0007222late adult stage
1.51e4
  • 1.51e4
32.45
  • 32.45
AEIR
  • AEIR
UBERON:0000992female gonad
  • UBERON:0000104life cycle
1.54e4
  • 1.54e4
31.17
  • 31.17
AEIR
  • AEIR
UBERON:0002371bone marrow
  • UBERON:0007222late adult stage
1.56e4
  • 1.56e4
30.11
  • 30.11
AEIR
  • AEIR
Sources
AAffymetrix
EEST
IIn Situ
RRNA-Seq
data
no data
Rank scores
3.25e4lightgrey: low confidence scores

important score variation

Rank scores of expression calls are normalized across genes, conditions and species. Low score means that the gene is highly expressed in the condition. Max rank score in all species: 4.10e4. Min rank score varies across species.

Expression scores of expression calls use the minimum and maximum Rank of the species to normalize the expression to a value between 0 and 100. Low score means that the gene is lowly expressed in the condition.

Sources of annotations to anatomy and development:
  • RNA-Seq data: Bgee
Sources of raw data:
  • RNA-Seq data: GEO

Orthologs

Taxon nameSpecies with orthologsGene(s)Expression comparisonSee details
Carnivora1 species1 geneCompare expression
Laurasiatheria4 species4 genesCompare expression
Boreoeutheria12 species12 genesCompare expression
Theria13 species13 genesCompare expression
Mammalia14 species14 genesCompare expression
Amniota16 species16 genesCompare expression
Tetrapoda17 species17 genesCompare expression
Euteleostomi18 species18 genesCompare expression

Orthology information comes from OMA : ENSCAFG00000011587.

Cross-references

EnsemblENSCAFG00000011587 (NGEF)
HGNCHGNC:7807 (NGEF)
EMBLAAEX03014451, AAEX03014452
Uniprot/SPTREMBLF1PFV4, F1PFV4_CANLF

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