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C. lupus familiaris Gene: CFLAR - ENSCAFG00000012130 - Canis lupus familiaris (dog)

General information

Ensembl IDENSCAFG00000012130
NameCFLAR
DescriptionCASP8 and FADD like apoptosis regulator [Source:HGNC Symbol;Acc:HGNC:1876]
OrganismCanis lupus familiaris (dog)
Synonym(s)c-flip, cash, casp8ap1, casper, clarp, flame, flip, i-flice, mrit
Orthologs(s)19 orthologs

Expression

Anat. entity IDAnatomical entityDevelopmental stage(s)Rank scoreExpression scoreSources
CL:0000094granulocyte
  • UBERON:0000104life cycle
748
  • 748
96.66
  • 96.66
AEIR
  • AEIR
UBERON:0000029lymph node
  • UBERON:0007222late adult stage
  • UBERON:0000104life cycle
1.24e3
  • 1.24e3
  • 1.74e3
94.45
  • 94.45
  • 92.21
AEIR
  • AEIR
  • AEIR
UBERON:0000945stomach
  • UBERON:0007222late adult stage
  • UBERON:0000113post-juvenile adult stage
1.44e3
  • 1.44e3
  • 4.55e3
93.58
  • 93.58
  • 79.66
AEIR
  • AEIR
  • AEIR
UBERON:0002106spleen
  • UBERON:0000104life cycle
  • UBERON:0007222late adult stage
  • UBERON:0000113post-juvenile adult stage
1.58e3
  • 1.58e3
  • 1.88e3
  • 2.06e3
92.92
  • 92.92
  • 91.61
  • 90.81
AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0000178blood
  • UBERON:0000104life cycle
1.68e3
  • 1.68e3
92.48
  • 92.48
AEIR
  • AEIR
UBERON:0001264pancreas
  • UBERON:0007222late adult stage
  • UBERON:0000104life cycle
  • UBERON:0000113post-juvenile adult stage
1.91e3
  • 1.91e3
  • 4.29e3
  • 4.85e3
91.49
  • 91.49
  • 80.84
  • 78.34
AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0002371bone marrow
  • UBERON:0007222late adult stage
1.91e3
  • 1.91e3
91.47
  • 91.47
AEIR
  • AEIR
UBERON:0002048lung
  • UBERON:0007222late adult stage
  • UBERON:0000104life cycle
  • UBERON:0000112sexually immature stage
1.91e3
  • 1.91e3
  • 3.19e3
  • 5.31e3
91.45
  • 91.45
  • 85.74
  • 76.24
AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0001013adipose tissue
  • UBERON:0007222late adult stage
1.92e3
  • 1.92e3
91.41
  • 91.41
AEIR
  • AEIR
UBERON:0001044saliva-secreting gland
  • UBERON:0007222late adult stage
1.92e3
  • 1.92e3
91.41
  • 91.41
AEIR
  • AEIR
UBERON:0000014zone of skin
  • UBERON:0007222late adult stage
  • UBERON:0000104life cycle
2.02e3
  • 2.02e3
  • 3.22e3
90.98
  • 90.98
  • 85.59
AEIR
  • AEIR
  • AEIR
UBERON:0002037cerebellum
  • UBERON:0007222late adult stage
  • UBERON:0000104life cycle
2.22e3
  • 2.22e3
  • 4.74e3
90.06
  • 90.06
  • 78.80
AEIR
  • AEIR
  • AEIR
UBERON:0002418cartilage tissue
  • UBERON:0007222late adult stage
2.25e3
  • 2.25e3
89.93
  • 89.93
AEIR
  • AEIR
UBERON:0002107liver
  • UBERON:0007222late adult stage
  • UBERON:0018241prime adult stage
  • UBERON:0000104life cycle
  • UBERON:0000113post-juvenile adult stage
  • UBERON:0000112sexually immature stage
2.26e3
  • 2.26e3
  • 2.61e3
  • 2.66e3
  • 3.30e3
  • 3.34e3
89.90
  • 89.90
  • 88.33
  • 88.12
  • 85.25
  • 85.08
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0002108small intestine
  • UBERON:0007222late adult stage
  • UBERON:0000113post-juvenile adult stage
2.31e3
  • 2.31e3
  • 4.45e3
89.68
  • 89.68
  • 80.09
AEIR
  • AEIR
  • AEIR
UBERON:0000007pituitary gland
  • UBERON:0007222late adult stage
  • UBERON:0018241prime adult stage
2.35e3
  • 2.35e3
  • 3.60e3
89.50
  • 89.50
  • 83.92
AEIR
  • AEIR
  • AEIR
UBERON:0002078right cardiac atrium
  • UBERON:0007222late adult stage
2.52e3
  • 2.52e3
88.74
  • 88.74
AEIR
  • AEIR
UBERON:0002369adrenal gland
  • UBERON:0007222late adult stage
  • UBERON:0000104life cycle
2.58e3
  • 2.58e3
  • 2.83e3
88.45
  • 88.45
  • 87.35
AEIR
  • AEIR
  • AEIR
UBERON:0002079left cardiac atrium
  • UBERON:0007222late adult stage
2.62e3
  • 2.62e3
88.31
  • 88.31
AEIR
  • AEIR
UBERON:0000966retina
  • UBERON:0000104life cycle
2.71e3
  • 2.71e3
87.89
  • 87.89
AEIR
  • AEIR
UBERON:0002370thymus
  • UBERON:0000104life cycle
2.72e3
  • 2.72e3
87.83
  • 87.83
AEIR
  • AEIR
UBERON:0001235adrenal cortex
  • UBERON:0018241prime adult stage
2.72e3
  • 2.72e3
87.82
  • 87.82
AEIR
  • AEIR
UBERON:0001259mucosa of urinary bladder
  • UBERON:0000104life cycle
2.75e3
  • 2.75e3
87.72
  • 87.72
AEIR
  • AEIR
UBERON:0001911mammary gland
  • UBERON:0018241prime adult stage
  • UBERON:0000104life cycle
2.76e3
  • 2.76e3
  • 5.11e3
87.65
  • 87.65
  • 77.15
AEIR
  • AEIR
  • AEIR
UBERON:0002080heart right ventricle
  • UBERON:0007222late adult stage
2.77e3
  • 2.77e3
87.60
  • 87.60
AEIR
  • AEIR
CL:0000312keratinocyte
  • UBERON:0000104life cycle
2.80e3
  • 2.80e3
87.51
  • 87.51
AEIR
  • AEIR
UBERON:0001155colon
  • UBERON:0007222late adult stage
  • UBERON:0000104life cycle
2.83e3
  • 2.83e3
  • 4.10e3
87.36
  • 87.36
  • 81.66
AEIR
  • AEIR
  • AEIR
UBERON:0000362renal medulla
  • UBERON:0007222late adult stage
2.88e3
  • 2.88e3
87.12
  • 87.12
AEIR
  • AEIR
UBERON:0002073hair follicle
  • UBERON:0000104life cycle
2.98e3
  • 2.98e3
86.70
  • 86.70
AEIR
  • AEIR
UBERON:0010533metanephros cortex
  • UBERON:0007222late adult stage
3.12e3
  • 3.12e3
86.07
  • 86.07
AEIR
  • AEIR
UBERON:0001255urinary bladder
  • UBERON:0007222late adult stage
3.13e3
  • 3.13e3
86.00
  • 86.00
AEIR
  • AEIR
UBERON:0002046thyroid gland
  • UBERON:0007222late adult stage
3.14e3
  • 3.14e3
85.96
  • 85.96
AEIR
  • AEIR
UBERON:0002084heart left ventricle
  • UBERON:0007222late adult stage
  • UBERON:0018241prime adult stage
3.60e3
  • 3.60e3
  • 4.34e3
83.92
  • 83.92
  • 80.59
AEIR
  • AEIR
  • AEIR
UBERON:0003382cardiac muscle of left ventricle
  • UBERON:0000104life cycle
3.76e3
  • 3.76e3
83.18
  • 83.18
AEIR
  • AEIR
UBERON:0002240spinal cord
  • UBERON:0000104life cycle
3.78e3
  • 3.78e3
83.09
  • 83.09
AEIR
  • AEIR
UBERON:0002115jejunum
  • UBERON:0000104life cycle
3.84e3
  • 3.84e3
82.85
  • 82.85
AEIR
  • AEIR
UBERON:0001987placenta
  • UBERON:0000113post-juvenile adult stage
4.11e3
  • 4.11e3
81.64
  • 81.64
AEIR
  • AEIR
UBERON:0000992female gonad
  • UBERON:0000104life cycle
4.16e3
  • 4.16e3
81.42
  • 81.42
AEIR
  • AEIR
UBERON:0001134skeletal muscle tissue
  • UBERON:0007222late adult stage
  • UBERON:0000104life cycle
4.20e3
  • 4.20e3
  • 6.48e3
81.23
  • 81.23
  • 71.01
AEIR
  • AEIR
  • AEIR
UBERON:0002135mitral valve
  • UBERON:0018241prime adult stage
  • UBERON:0007222late adult stage
4.26e3
  • 4.26e3
  • 6.15e3
80.94
  • 80.94
  • 72.52
AEIR
  • AEIR
  • AEIR
UBERON:0016540occipital cortex
  • UBERON:0007222late adult stage
4.32e3
  • 4.32e3
80.69
  • 80.69
AEIR
  • AEIR
UBERON:0000948heart
  • UBERON:0000104life cycle
  • UBERON:0000112sexually immature stage
4.77e3
  • 4.77e3
  • 5.54e3
78.66
  • 78.66
  • 75.25
AEIR
  • AEIR
  • AEIR
UBERON:0000004nose
  • UBERON:0000104life cycle
4.81e3
  • 4.81e3
78.52
  • 78.52
AEIR
  • AEIR
UBERON:0000082adult mammalian kidney
  • UBERON:0000112sexually immature stage
  • UBERON:0018241prime adult stage
5.04e3
  • 5.04e3
  • 6.20e3
77.47
  • 77.47
  • 72.28
AEIR
  • AEIR
  • AEIR
UBERON:0002264olfactory bulb
  • UBERON:0000104life cycle
5.11e3
  • 5.11e3
77.14
  • 77.14
AEIR
  • AEIR
UBERON:0001723tongue
  • UBERON:0000113post-juvenile adult stage
5.87e3
  • 5.87e3
73.74
  • 73.74
AEIR
  • AEIR
UBERON:0001870frontal cortex
  • UBERON:0007222late adult stage
6.08e3
  • 6.08e3
72.82
  • 72.82
AEIR
  • AEIR
UBERON:0001898hypothalamus
  • UBERON:0000104life cycle
6.33e3
  • 6.33e3
71.69
  • 71.69
AEIR
  • AEIR
UBERON:0001135smooth muscle tissue
  • UBERON:0000104life cycle
6.35e3
  • 6.35e3
71.60
  • 71.60
AEIR
  • AEIR
UBERON:0000451prefrontal cortex
  • UBERON:0018241prime adult stage
6.92e3
  • 6.92e3
69.05
  • 69.05
AEIR
  • AEIR
UBERON:0001871temporal lobe
  • UBERON:0000113post-juvenile adult stage
7.19e3
  • 7.19e3
67.86
  • 67.86
AEIR
  • AEIR
UBERON:0000033head
  • UBERON:0000112sexually immature stage
7.41e3
  • 7.41e3
66.86
  • 66.86
AEIR
  • AEIR
UBERON:0000473testis
  • UBERON:0000104life cycle
1.20e4
  • 1.20e4
46.36
  • 46.36
AEIR
  • AEIR
Sources
AAffymetrix
EEST
IIn Situ
RRNA-Seq
data
no data
Rank scores
3.25e4lightgrey: low confidence scores

important score variation

Rank scores of expression calls are normalized across genes, conditions and species. Low score means that the gene is highly expressed in the condition. Max rank score in all species: 4.10e4. Min rank score varies across species.

Expression scores of expression calls use the minimum and maximum Rank of the species to normalize the expression to a value between 0 and 100. Low score means that the gene is lowly expressed in the condition.

Sources of annotations to anatomy and development:
  • RNA-Seq data: Bgee
Sources of raw data:
  • RNA-Seq data: GEO

Orthologs

Taxon nameSpecies with orthologsGene(s)Expression comparisonSee details
Carnivora1 species1 geneCompare expression
Laurasiatheria5 species5 genesCompare expression
Boreoeutheria13 species13 genesCompare expression
Theria14 species14 genesCompare expression
Mammalia15 species15 genesCompare expression
Amniota17 species17 genesCompare expression
Tetrapoda18 species18 genesCompare expression
Euteleostomi19 species19 genesCompare expression

Orthology information comes from OMA : ENSCAFG00000012130.

Cross-references

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