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C. lupus familiaris Gene: MAP3K6 - ENSCAFG00000012144 - Canis lupus familiaris (dog)

General information

Ensembl IDENSCAFG00000012144
NameMAP3K6
Descriptionmitogen-activated protein kinase kinase kinase 6 [Source:HGNC Symbol;Acc:HGNC:6858]
OrganismCanis lupus familiaris (dog)
Synonym(s)ask2, mapkkk6, mekk6
Orthologs(s)16 orthologs

Expression

Anat. entity IDAnatomical entityDevelopmental stage(s)Rank scoreExpression scoreSources
UBERON:0000004nose
  • UBERON:0000104life cycle
4.91e3
  • 4.91e3
78.04
  • 78.04
AEIR
  • AEIR
UBERON:0000955brain
  • UBERON:0018241prime adult stage
  • UBERON:0000104life cycle
5.32e3
  • 5.32e3
  • 1.61e4
76.21
  • 76.21
  • 27.90
AEIR
  • AEIR
  • AEIR
UBERON:0002106spleen
  • UBERON:0000104life cycle
  • UBERON:0000113post-juvenile adult stage
  • UBERON:0007222late adult stage
5.51e3
  • 5.51e3
  • 9.57e3
  • 9.92e3
75.35
  • 75.35
  • 57.20
  • 55.64
AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0001911mammary gland
  • UBERON:0000104life cycle
  • UBERON:0018241prime adult stage
5.86e3
  • 5.86e3
  • 1.01e4
73.81
  • 73.81
  • 54.66
AEIR
  • AEIR
  • AEIR
UBERON:0002073hair follicle
  • UBERON:0000104life cycle
6.01e3
  • 6.01e3
73.12
  • 73.12
AEIR
  • AEIR
UBERON:0002135mitral valve
  • UBERON:0007222late adult stage
  • UBERON:0018241prime adult stage
8.25e3
  • 8.25e3
  • 1.04e4
63.13
  • 63.13
  • 53.38
AEIR
  • AEIR
  • AEIR
UBERON:0000014zone of skin
  • UBERON:0000104life cycle
  • UBERON:0007222late adult stage
8.62e3
  • 8.62e3
  • 1.23e4
61.47
  • 61.47
  • 44.78
AEIR
  • AEIR
  • AEIR
UBERON:0000082adult mammalian kidney
  • UBERON:0018241prime adult stage
  • UBERON:0000112sexually immature stage
8.75e3
  • 8.75e3
  • 1.33e4
60.89
  • 60.89
  • 40.35
AEIR
  • AEIR
  • AEIR
UBERON:0000059large intestine
  • UBERON:0000113post-juvenile adult stage
9.26e3
  • 9.26e3
58.59
  • 58.59
AEIR
  • AEIR
UBERON:0001155colon
  • UBERON:0000104life cycle
  • UBERON:0007222late adult stage
9.47e3
  • 9.47e3
  • 1.26e4
57.64
  • 57.64
  • 43.80
AEIR
  • AEIR
  • AEIR
UBERON:0003382cardiac muscle of left ventricle
  • UBERON:0000104life cycle
9.48e3
  • 9.48e3
57.61
  • 57.61
AEIR
  • AEIR
UBERON:0000945stomach
  • UBERON:0000113post-juvenile adult stage
  • UBERON:0007222late adult stage
9.58e3
  • 9.58e3
  • 1.18e4
57.18
  • 57.18
  • 47.20
AEIR
  • AEIR
  • AEIR
UBERON:0000948heart
  • UBERON:0000104life cycle
  • UBERON:0000112sexually immature stage
9.64e3
  • 9.64e3
  • 1.39e4
56.88
  • 56.88
  • 37.79
AEIR
  • AEIR
  • AEIR
UBERON:0002084heart left ventricle
  • UBERON:0018241prime adult stage
  • UBERON:0007222late adult stage
9.80e3
  • 9.80e3
  • 1.03e4
56.16
  • 56.16
  • 54.01
AEIR
  • AEIR
  • AEIR
UBERON:0002370thymus
  • UBERON:0000104life cycle
9.82e3
  • 9.82e3
56.09
  • 56.09
AEIR
  • AEIR
UBERON:0001264pancreas
  • UBERON:0000104life cycle
  • UBERON:0007222late adult stage
  • UBERON:0000113post-juvenile adult stage
9.94e3
  • 9.94e3
  • 1.01e4
  • 1.05e4
55.57
  • 55.57
  • 54.72
  • 53.10
AEIR
  • AEIR
  • AEIR
  • AEIR
CL:0000312keratinocyte
  • UBERON:0000104life cycle
1.01e4
  • 1.01e4
54.83
  • 54.83
AEIR
  • AEIR
UBERON:0001987placenta
  • UBERON:0000113post-juvenile adult stage
1.05e4
  • 1.05e4
53.14
  • 53.14
AEIR
  • AEIR
UBERON:0002107liver
  • UBERON:0000112sexually immature stage
  • UBERON:0000104life cycle
  • UBERON:0000113post-juvenile adult stage
  • UBERON:0018241prime adult stage
  • UBERON:0007222late adult stage
1.07e4
  • 1.07e4
  • 1.12e4
  • 1.12e4
  • 1.15e4
  • 1.16e4
52.21
  • 52.21
  • 50.09
  • 49.94
  • 48.74
  • 48.14
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0001044saliva-secreting gland
  • UBERON:0007222late adult stage
1.07e4
  • 1.07e4
52.18
  • 52.18
AEIR
  • AEIR
UBERON:0002108small intestine
  • UBERON:0000113post-juvenile adult stage
  • UBERON:0007222late adult stage
1.09e4
  • 1.09e4
  • 1.27e4
51.26
  • 51.26
  • 43.12
AEIR
  • AEIR
  • AEIR
UBERON:0000178blood
  • UBERON:0000104life cycle
1.10e4
  • 1.10e4
51.00
  • 51.00
AEIR
  • AEIR
UBERON:0001723tongue
  • UBERON:0000113post-juvenile adult stage
1.10e4
  • 1.10e4
50.89
  • 50.89
AEIR
  • AEIR
UBERON:0001259mucosa of urinary bladder
  • UBERON:0000104life cycle
1.11e4
  • 1.11e4
50.39
  • 50.39
AEIR
  • AEIR
UBERON:0002046thyroid gland
  • UBERON:0007222late adult stage
1.12e4
  • 1.12e4
49.72
  • 49.72
AEIR
  • AEIR
UBERON:0002115jejunum
  • UBERON:0000104life cycle
1.13e4
  • 1.13e4
49.39
  • 49.39
AEIR
  • AEIR
UBERON:0000029lymph node
  • UBERON:0000104life cycle
  • UBERON:0007222late adult stage
1.13e4
  • 1.13e4
  • 1.30e4
49.26
  • 49.26
  • 41.95
AEIR
  • AEIR
  • AEIR
UBERON:0001013adipose tissue
  • UBERON:0007222late adult stage
1.15e4
  • 1.15e4
48.37
  • 48.37
AEIR
  • AEIR
UBERON:0000966retina
  • UBERON:0000104life cycle
1.16e4
  • 1.16e4
48.21
  • 48.21
AEIR
  • AEIR
UBERON:0002369adrenal gland
  • UBERON:0000104life cycle
  • UBERON:0007222late adult stage
1.18e4
  • 1.18e4
  • 1.25e4
47.30
  • 47.30
  • 44.31
AEIR
  • AEIR
  • AEIR
UBERON:0002078right cardiac atrium
  • UBERON:0007222late adult stage
1.19e4
  • 1.19e4
46.80
  • 46.80
AEIR
  • AEIR
UBERON:0000362renal medulla
  • UBERON:0007222late adult stage
1.19e4
  • 1.19e4
46.69
  • 46.69
AEIR
  • AEIR
UBERON:0002080heart right ventricle
  • UBERON:0007222late adult stage
1.19e4
  • 1.19e4
46.60
  • 46.60
AEIR
  • AEIR
UBERON:0002048lung
  • UBERON:0000104life cycle
  • UBERON:0000112sexually immature stage
  • UBERON:0007222late adult stage
1.20e4
  • 1.20e4
  • 1.22e4
  • 1.33e4
46.38
  • 46.38
  • 45.23
  • 40.74
AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0001255urinary bladder
  • UBERON:0007222late adult stage
1.21e4
  • 1.21e4
46.07
  • 46.07
AEIR
  • AEIR
UBERON:0001235adrenal cortex
  • UBERON:0018241prime adult stage
1.22e4
  • 1.22e4
45.65
  • 45.65
AEIR
  • AEIR
UBERON:0002371bone marrow
  • UBERON:0007222late adult stage
1.24e4
  • 1.24e4
44.74
  • 44.74
AEIR
  • AEIR
UBERON:0000007pituitary gland
  • UBERON:0018241prime adult stage
  • UBERON:0007222late adult stage
1.24e4
  • 1.24e4
  • 1.39e4
44.59
  • 44.59
  • 37.66
AEIR
  • AEIR
  • AEIR
UBERON:0000992female gonad
  • UBERON:0000104life cycle
1.26e4
  • 1.26e4
43.67
  • 43.67
AEIR
  • AEIR
UBERON:0010533metanephros cortex
  • UBERON:0007222late adult stage
1.28e4
  • 1.28e4
42.81
  • 42.81
AEIR
  • AEIR
UBERON:0001135smooth muscle tissue
  • UBERON:0000104life cycle
1.29e4
  • 1.29e4
42.48
  • 42.48
AEIR
  • AEIR
UBERON:0001134skeletal muscle tissue
  • UBERON:0000104life cycle
  • UBERON:0007222late adult stage
1.29e4
  • 1.29e4
  • 1.41e4
42.48
  • 42.48
  • 36.98
AEIR
  • AEIR
  • AEIR
UBERON:0002418cartilage tissue
  • UBERON:0007222late adult stage
1.30e4
  • 1.30e4
41.68
  • 41.68
AEIR
  • AEIR
UBERON:0002021occipital lobe
  • UBERON:0000113post-juvenile adult stage
1.41e4
  • 1.41e4
36.77
  • 36.77
AEIR
  • AEIR
UBERON:0002037cerebellum
  • UBERON:0000104life cycle
1.46e4
  • 1.46e4
34.88
  • 34.88
AEIR
  • AEIR
UBERON:0000033head
  • UBERON:0000112sexually immature stage
1.46e4
  • 1.46e4
34.87
  • 34.87
AEIR
  • AEIR
UBERON:0002240spinal cord
  • UBERON:0000104life cycle
1.47e4
  • 1.47e4
34.37
  • 34.37
AEIR
  • AEIR
UBERON:0001871temporal lobe
  • UBERON:0000113post-juvenile adult stage
1.47e4
  • 1.47e4
34.12
  • 34.12
AEIR
  • AEIR
UBERON:0002264olfactory bulb
  • UBERON:0000104life cycle
1.48e4
  • 1.48e4
33.69
  • 33.69
AEIR
  • AEIR
UBERON:0000451prefrontal cortex
  • UBERON:0018241prime adult stage
1.52e4
  • 1.52e4
32.18
  • 32.18
AEIR
  • AEIR
UBERON:0001870frontal cortex
  • UBERON:0007222late adult stage
1.52e4
  • 1.52e4
32.13
  • 32.13
AEIR
  • AEIR
UBERON:0016540occipital cortex
  • UBERON:0007222late adult stage
1.57e4
  • 1.57e4
29.96
  • 29.96
AEIR
  • AEIR
UBERON:0001898hypothalamus
  • UBERON:0000104life cycle
1.58e4
  • 1.58e4
29.23
  • 29.23
AEIR
  • AEIR
UBERON:0000473testis
  • UBERON:0000104life cycle
1.62e4
  • 1.62e4
27.67
  • 27.67
AEIR
  • AEIR
Sources
AAffymetrix
EEST
IIn Situ
RRNA-Seq
data
no data
Rank scores
3.25e4lightgrey: low confidence scores

important score variation

Rank scores of expression calls are normalized across genes, conditions and species. Low score means that the gene is highly expressed in the condition. Max rank score in all species: 4.10e4. Min rank score varies across species.

Expression scores of expression calls use the minimum and maximum Rank of the species to normalize the expression to a value between 0 and 100. Low score means that the gene is lowly expressed in the condition.

Sources of annotations to anatomy and development:
  • RNA-Seq data: Bgee
Sources of raw data:
  • RNA-Seq data: GEO

Orthologs

Taxon nameSpecies with orthologsGene(s)Expression comparisonSee details
Carnivora1 species1 geneCompare expression
Laurasiatheria5 species5 genesCompare expression
Boreoeutheria13 species13 genesCompare expression
Theria14 species14 genesCompare expression
Amniota16 species16 genesCompare expression

Orthology information comes from OMA : ENSCAFG00000012144.

Cross-references

EnsemblENSCAFG00000012144 (MAP3K6)
HGNCHGNC:6858 (MAP3K6)
EMBLAAEX03001716
Uniprot/SPTREMBLF1P6H0, F1P6H0_CANLF

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