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C. lupus familiaris Gene: CLDN4 - ENSCAFG00000012523 - Canis lupus familiaris (dog)

General information

Ensembl IDENSCAFG00000012523
NameCLDN4
Descriptionclaudin 4 [Source:HGNC Symbol;Acc:HGNC:2046]
OrganismCanis lupus familiaris (dog)
Synonym(s)cpe-r, cpetr, cpetr1, hcpe-r, wbscr8
Orthologs(s)17 orthologs
Paralog(s)6 paralogs

Expression

Anat. entity IDAnatomical entityDevelopmental stage(s)Rank scoreExpression scoreSources
UBERON:0001259mucosa of urinary bladder
  • UBERON:0000104life cycle
124
  • 124
99.45
  • 99.45
AEIR
  • AEIR
UBERON:0001987placenta
  • UBERON:0000113post-juvenile adult stage
564
  • 564
97.48
  • 97.48
AEIR
  • AEIR
UBERON:0002073hair follicle
  • UBERON:0000104life cycle
566
  • 566
97.47
  • 97.47
AEIR
  • AEIR
UBERON:0000059large intestine
  • UBERON:0000113post-juvenile adult stage
614
  • 614
97.26
  • 97.26
AEIR
  • AEIR
UBERON:0001264pancreas
  • UBERON:0007222late adult stage
  • UBERON:0000113post-juvenile adult stage
  • UBERON:0000104life cycle
673
  • 673
  • 1.04e3
  • 3.17e3
96.99
  • 96.99
  • 95.35
  • 85.82
AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0001911mammary gland
  • UBERON:0018241prime adult stage
  • UBERON:0000104life cycle
887
  • 887
  • 2.03e3
96.04
  • 96.04
  • 90.94
AEIR
  • AEIR
  • AEIR
UBERON:0001155colon
  • UBERON:0000104life cycle
  • UBERON:0007222late adult stage
1.22e3
  • 1.22e3
  • 1.56e4
94.53
  • 94.53
  • 30.42
AEIR
  • AEIR
  • AEIR
UBERON:0002113kidney
  • UBERON:0000104life cycle
1.33e3
  • 1.33e3
94.05
  • 94.05
AEIR
  • AEIR
UBERON:0001255urinary bladder
  • UBERON:0007222late adult stage
1.52e3
  • 1.52e3
93.20
  • 93.20
AEIR
  • AEIR
UBERON:0001044saliva-secreting gland
  • UBERON:0007222late adult stage
1.72e3
  • 1.72e3
92.30
  • 92.30
AEIR
  • AEIR
UBERON:0002048lung
  • UBERON:0000104life cycle
  • UBERON:0007222late adult stage
  • UBERON:0000112sexually immature stage
1.85e3
  • 1.85e3
  • 4.61e3
  • 7.64e3
91.72
  • 91.72
  • 79.41
  • 65.85
AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0000014zone of skin
  • UBERON:0007222late adult stage
  • UBERON:0000104life cycle
2.49e3
  • 2.49e3
  • 5.76e3
88.87
  • 88.87
  • 74.26
AEIR
  • AEIR
  • AEIR
UBERON:0000004nose
  • UBERON:0000104life cycle
3.05e3
  • 3.05e3
86.36
  • 86.36
AEIR
  • AEIR
UBERON:0002107liver
  • UBERON:0007222late adult stage
  • UBERON:0018241prime adult stage
  • UBERON:0000113post-juvenile adult stage
  • UBERON:0000104life cycle
  • UBERON:0000112sexually immature stage
3.08e3
  • 3.08e3
  • 3.12e3
  • 3.18e3
  • 3.54e3
  • 6.82e3
86.22
  • 86.22
  • 86.04
  • 85.77
  • 84.17
  • 69.49
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0002106spleen
  • UBERON:0000113post-juvenile adult stage
  • UBERON:0000104life cycle
3.18e3
  • 3.18e3
  • 1.12e4
85.79
  • 85.79
  • 50.12
AEIR
  • AEIR
  • AEIR
UBERON:0000992female gonad
  • UBERON:0000104life cycle
3.37e3
  • 3.37e3
84.94
  • 84.94
AEIR
  • AEIR
UBERON:0010533metanephros cortex
  • UBERON:0007222late adult stage
3.41e3
  • 3.41e3
84.76
  • 84.76
AEIR
  • AEIR
UBERON:0000948heart
  • UBERON:0000104life cycle
  • UBERON:0000112sexually immature stage
3.86e3
  • 3.86e3
  • 1.37e4
82.73
  • 82.73
  • 38.67
AEIR
  • AEIR
  • AEIR
UBERON:0000362renal medulla
  • UBERON:0007222late adult stage
3.94e3
  • 3.94e3
82.38
  • 82.38
AEIR
  • AEIR
UBERON:0000082adult mammalian kidney
  • UBERON:0018241prime adult stage
  • UBERON:0000112sexually immature stage
4.15e3
  • 4.15e3
  • 6.28e3
81.45
  • 81.45
  • 71.93
AEIR
  • AEIR
  • AEIR
UBERON:0002115jejunum
  • UBERON:0000104life cycle
4.76e3
  • 4.76e3
78.72
  • 78.72
AEIR
  • AEIR
UBERON:0002084heart left ventricle
  • UBERON:0018241prime adult stage
  • UBERON:0007222late adult stage
5.04e3
  • 5.04e3
  • 5.64e3
77.45
  • 77.45
  • 74.80
AEIR
  • AEIR
  • AEIR
UBERON:0001013adipose tissue
  • UBERON:0007222late adult stage
5.13e3
  • 5.13e3
77.07
  • 77.07
AEIR
  • AEIR
UBERON:0002135mitral valve
  • UBERON:0007222late adult stage
  • UBERON:0018241prime adult stage
5.39e3
  • 5.39e3
  • 5.46e3
75.90
  • 75.90
  • 75.58
AEIR
  • AEIR
  • AEIR
CL:0000312keratinocyte
  • UBERON:0000104life cycle
6.69e3
  • 6.69e3
70.09
  • 70.09
AEIR
  • AEIR
UBERON:0002108small intestine
  • UBERON:0000113post-juvenile adult stage
7.13e3
  • 7.13e3
68.13
  • 68.13
AEIR
  • AEIR
UBERON:0001135smooth muscle tissue
  • UBERON:0000104life cycle
7.71e3
  • 7.71e3
65.53
  • 65.53
AEIR
  • AEIR
UBERON:0001134skeletal muscle tissue
  • UBERON:0000104life cycle
  • UBERON:0007222late adult stage
7.73e3
  • 7.73e3
  • 1.41e4
65.46
  • 65.46
  • 36.94
AEIR
  • AEIR
  • AEIR
UBERON:0002371bone marrow
  • UBERON:0007222late adult stage
7.94e3
  • 7.94e3
64.48
  • 64.48
AEIR
  • AEIR
UBERON:0003382cardiac muscle of left ventricle
  • UBERON:0000104life cycle
1.07e4
  • 1.07e4
51.94
  • 51.94
AEIR
  • AEIR
UBERON:0000007pituitary gland
  • UBERON:0018241prime adult stage
  • UBERON:0007222late adult stage
1.14e4
  • 1.14e4
  • 1.42e4
49.18
  • 49.18
  • 36.34
AEIR
  • AEIR
  • AEIR
UBERON:0002078right cardiac atrium
  • UBERON:0007222late adult stage
1.17e4
  • 1.17e4
47.83
  • 47.83
AEIR
  • AEIR
UBERON:0002021occipital lobe
  • UBERON:0000113post-juvenile adult stage
1.19e4
  • 1.19e4
46.64
  • 46.64
AEIR
  • AEIR
UBERON:0002369adrenal gland
  • UBERON:0000104life cycle
1.19e4
  • 1.19e4
46.60
  • 46.60
AEIR
  • AEIR
UBERON:0002080heart right ventricle
  • UBERON:0007222late adult stage
1.23e4
  • 1.23e4
45.15
  • 45.15
AEIR
  • AEIR
UBERON:0002046thyroid gland
  • UBERON:0007222late adult stage
1.24e4
  • 1.24e4
44.43
  • 44.43
AEIR
  • AEIR
UBERON:0000178blood
  • UBERON:0000104life cycle
1.25e4
  • 1.25e4
43.97
  • 43.97
AEIR
  • AEIR
UBERON:0002418cartilage tissue
  • UBERON:0007222late adult stage
1.28e4
  • 1.28e4
42.58
  • 42.58
AEIR
  • AEIR
UBERON:0002370thymus
  • UBERON:0000104life cycle
1.30e4
  • 1.30e4
41.99
  • 41.99
AEIR
  • AEIR
UBERON:0000029lymph node
  • UBERON:0007222late adult stage
  • UBERON:0000104life cycle
1.32e4
  • 1.32e4
  • 1.97e4
41.10
  • 41.10
  • 12.03
AEIR
  • AEIR
  • AEIR
UBERON:0001235adrenal cortex
  • UBERON:0018241prime adult stage
1.35e4
  • 1.35e4
39.76
  • 39.76
AEIR
  • AEIR
UBERON:0001871temporal lobe
  • UBERON:0000113post-juvenile adult stage
1.36e4
  • 1.36e4
39.16
  • 39.16
AEIR
  • AEIR
UBERON:0000033head
  • UBERON:0000112sexually immature stage
1.46e4
  • 1.46e4
34.57
  • 34.57
AEIR
  • AEIR
UBERON:0000945stomach
  • UBERON:0000113post-juvenile adult stage
1.47e4
  • 1.47e4
34.10
  • 34.10
AEIR
  • AEIR
UBERON:0002264olfactory bulb
  • UBERON:0000104life cycle
1.54e4
  • 1.54e4
30.93
  • 30.93
AEIR
  • AEIR
UBERON:0016540occipital cortex
  • UBERON:0007222late adult stage
1.55e4
  • 1.55e4
30.70
  • 30.70
AEIR
  • AEIR
UBERON:0000451prefrontal cortex
  • UBERON:0018241prime adult stage
1.56e4
  • 1.56e4
30.39
  • 30.39
AEIR
  • AEIR
UBERON:0000966retina
  • UBERON:0000104life cycle
1.57e4
  • 1.57e4
29.86
  • 29.86
AEIR
  • AEIR
UBERON:0002037cerebellum
  • UBERON:0000104life cycle
1.64e4
  • 1.64e4
26.50
  • 26.50
AEIR
  • AEIR
UBERON:0001723tongue
  • UBERON:0000113post-juvenile adult stage
1.65e4
  • 1.65e4
26.33
  • 26.33
AEIR
  • AEIR
UBERON:0000473testis
  • UBERON:0000104life cycle
1.66e4
  • 1.66e4
25.66
  • 25.66
AEIR
  • AEIR
UBERON:0001870frontal cortex
  • UBERON:0007222late adult stage
1.79e4
  • 1.79e4
19.75
  • 19.75
AEIR
  • AEIR
Sources
AAffymetrix
EEST
IIn Situ
RRNA-Seq
data
no data
Rank scores
3.25e4lightgrey: low confidence scores

important score variation

Rank scores of expression calls are normalized across genes, conditions and species. Low score means that the gene is highly expressed in the condition. Max rank score in all species: 4.10e4. Min rank score varies across species.

Expression scores of expression calls use the minimum and maximum Rank of the species to normalize the expression to a value between 0 and 100. Low score means that the gene is lowly expressed in the condition.

Sources of annotations to anatomy and development:
  • RNA-Seq data: Bgee
Sources of raw data:
  • RNA-Seq data: GEO

Orthologs

Taxon nameSpecies with orthologsGene(s)Expression comparisonSee details
Carnivora1 species1 geneCompare expression
Laurasiatheria5 species5 genesCompare expression
Boreoeutheria12 species12 genesCompare expression
Theria13 species13 genesCompare expression
Mammalia14 species14 genesCompare expression
Amniota16 species16 genesCompare expression
Tetrapoda17 species17 genesCompare expression

Orthology information comes from OMA : ENSCAFG00000012523.

Paralogs (same species)

Taxon nameGene(s)Expression comparisonSee details
Sarcopterygii1 geneCompare expression
Chordata6 genesCompare expression

Paralogy information comes from OMA : ENSCAFG00000012523.

Cross-references

EnsemblENSCAFG00000012523 (CLDN4)
HGNCHGNC:2046 (CLDN4)
EMBLAAEX03004239
Uniprot/SPTREMBLE2RNC2, E2RNC2_CANLF

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