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C. lupus familiaris Gene: HTRA1 - ENSCAFG00000012556 - Canis lupus familiaris (dog)

General information

Ensembl IDENSCAFG00000012556
NameHTRA1
DescriptionHtrA serine peptidase 1 [Source:HGNC Symbol;Acc:HGNC:9476]
OrganismCanis lupus familiaris (dog)
Synonym(s)armd7, htra, igfbp5-protease, prss11
Orthologs(s)15 orthologs
Paralog(s)2 paralogs

Expression

Anat. entity IDAnatomical entityDevelopmental stage(s)Rank scoreExpression scoreSources
UBERON:0002418cartilage tissue
  • UBERON:0007222late adult stage
42.0
  • 42.0
99.82
  • 99.82
AEIR
  • AEIR
UBERON:0001987placenta
  • UBERON:0000113post-juvenile adult stage
54.0
  • 54.0
99.76
  • 99.76
AEIR
  • AEIR
CL:0000312keratinocyte
  • UBERON:0000104life cycle
198
  • 198
99.12
  • 99.12
AEIR
  • AEIR
UBERON:0002240spinal cord
  • UBERON:0000104life cycle
216
  • 216
99.04
  • 99.04
AEIR
  • AEIR
UBERON:0001898hypothalamus
  • UBERON:0000104life cycle
243
  • 243
98.92
  • 98.92
AEIR
  • AEIR
UBERON:0002264olfactory bulb
  • UBERON:0000104life cycle
310
  • 310
98.62
  • 98.62
AEIR
  • AEIR
UBERON:0002021occipital lobe
  • UBERON:0000113post-juvenile adult stage
367
  • 367
98.36
  • 98.36
AEIR
  • AEIR
UBERON:0001871temporal lobe
  • UBERON:0000113post-juvenile adult stage
410
  • 410
98.17
  • 98.17
AEIR
  • AEIR
UBERON:0000966retina
  • UBERON:0000104life cycle
414
  • 414
98.15
  • 98.15
AEIR
  • AEIR
UBERON:0000451prefrontal cortex
  • UBERON:0018241prime adult stage
425
  • 425
98.10
  • 98.10
AEIR
  • AEIR
UBERON:0000014zone of skin
  • UBERON:0007222late adult stage
  • UBERON:0000104life cycle
464
  • 464
  • 2.29e3
97.93
  • 97.93
  • 89.75
AEIR
  • AEIR
  • AEIR
UBERON:0000992female gonad
  • UBERON:0000104life cycle
552
  • 552
97.54
  • 97.54
AEIR
  • AEIR
UBERON:0001870frontal cortex
  • UBERON:0007222late adult stage
585
  • 585
97.39
  • 97.39
AEIR
  • AEIR
UBERON:0001911mammary gland
  • UBERON:0000104life cycle
  • UBERON:0018241prime adult stage
594
  • 594
  • 625
97.35
  • 97.35
  • 97.21
AEIR
  • AEIR
  • AEIR
UBERON:0002037cerebellum
  • UBERON:0000104life cycle
  • UBERON:0007222late adult stage
615
  • 615
  • 727
97.25
  • 97.25
  • 96.75
AEIR
  • AEIR
  • AEIR
UBERON:0016540occipital cortex
  • UBERON:0007222late adult stage
673
  • 673
96.99
  • 96.99
AEIR
  • AEIR
UBERON:0000362renal medulla
  • UBERON:0007222late adult stage
694
  • 694
96.90
  • 96.90
AEIR
  • AEIR
UBERON:0000029lymph node
  • UBERON:0007222late adult stage
  • UBERON:0000104life cycle
717
  • 717
  • 3.11e3
96.80
  • 96.80
  • 86.10
AEIR
  • AEIR
  • AEIR
UBERON:0001013adipose tissue
  • UBERON:0007222late adult stage
728
  • 728
96.75
  • 96.75
AEIR
  • AEIR
UBERON:0000945stomach
  • UBERON:0007222late adult stage
  • UBERON:0000113post-juvenile adult stage
758
  • 758
  • 1.48e3
96.61
  • 96.61
  • 93.40
AEIR
  • AEIR
  • AEIR
UBERON:0002369adrenal gland
  • UBERON:0007222late adult stage
  • UBERON:0000104life cycle
965
  • 965
  • 2.29e3
95.69
  • 95.69
  • 89.75
AEIR
  • AEIR
  • AEIR
UBERON:0001155colon
  • UBERON:0007222late adult stage
  • UBERON:0000104life cycle
987
  • 987
  • 2.04e3
95.59
  • 95.59
  • 90.88
AEIR
  • AEIR
  • AEIR
UBERON:0002135mitral valve
  • UBERON:0018241prime adult stage
  • UBERON:0007222late adult stage
1.02e3
  • 1.02e3
  • 1.04e3
95.45
  • 95.45
  • 95.34
AEIR
  • AEIR
  • AEIR
UBERON:0010533metanephros cortex
  • UBERON:0007222late adult stage
1.04e3
  • 1.04e3
95.37
  • 95.37
AEIR
  • AEIR
UBERON:0001264pancreas
  • UBERON:0007222late adult stage
  • UBERON:0000113post-juvenile adult stage
  • UBERON:0000104life cycle
1.28e3
  • 1.28e3
  • 1.46e3
  • 2.70e3
94.28
  • 94.28
  • 93.48
  • 87.94
AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0000004nose
  • UBERON:0000104life cycle
1.39e3
  • 1.39e3
93.78
  • 93.78
AEIR
  • AEIR
UBERON:0001259mucosa of urinary bladder
  • UBERON:0000104life cycle
1.49e3
  • 1.49e3
93.35
  • 93.35
AEIR
  • AEIR
UBERON:0002371bone marrow
  • UBERON:0007222late adult stage
1.49e3
  • 1.49e3
93.35
  • 93.35
AEIR
  • AEIR
UBERON:0000007pituitary gland
  • UBERON:0007222late adult stage
  • UBERON:0018241prime adult stage
1.50e3
  • 1.50e3
  • 2.23e3
93.28
  • 93.28
  • 90.05
AEIR
  • AEIR
  • AEIR
UBERON:0000948heart
  • UBERON:0000112sexually immature stage
  • UBERON:0000104life cycle
1.51e3
  • 1.51e3
  • 3.69e3
93.27
  • 93.27
  • 83.52
AEIR
  • AEIR
  • AEIR
UBERON:0002107liver
  • UBERON:0000113post-juvenile adult stage
  • UBERON:0007222late adult stage
  • UBERON:0000104life cycle
  • UBERON:0018241prime adult stage
  • UBERON:0000112sexually immature stage
1.51e3
  • 1.51e3
  • 1.70e3
  • 2.18e3
  • 2.78e3
  • 6.66e3
93.26
  • 93.26
  • 92.41
  • 90.25
  • 87.59
  • 70.24
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0000473testis
  • UBERON:0000104life cycle
  • UBERON:0018241prime adult stage
1.54e3
  • 1.54e3
  • 3.10e3
93.13
  • 93.13
  • 86.14
AEIR
  • AEIR
  • AEIR
UBERON:0002048lung
  • UBERON:0007222late adult stage
  • UBERON:0000104life cycle
  • UBERON:0000112sexually immature stage
1.54e3
  • 1.54e3
  • 1.91e3
  • 2.66e3
93.12
  • 93.12
  • 91.45
  • 88.11
AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0002073hair follicle
  • UBERON:0000104life cycle
1.63e3
  • 1.63e3
92.72
  • 92.72
AEIR
  • AEIR
UBERON:0001255urinary bladder
  • UBERON:0007222late adult stage
1.73e3
  • 1.73e3
92.26
  • 92.26
AEIR
  • AEIR
UBERON:0002108small intestine
  • UBERON:0007222late adult stage
  • UBERON:0000113post-juvenile adult stage
1.77e3
  • 1.77e3
  • 2.29e3
92.11
  • 92.11
  • 89.77
AEIR
  • AEIR
  • AEIR
UBERON:0002106spleen
  • UBERON:0000113post-juvenile adult stage
  • UBERON:0007222late adult stage
  • UBERON:0000104life cycle
1.78e3
  • 1.78e3
  • 1.91e3
  • 2.13e3
92.03
  • 92.03
  • 91.46
  • 90.49
AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0002078right cardiac atrium
  • UBERON:0007222late adult stage
2.08e3
  • 2.08e3
90.70
  • 90.70
AEIR
  • AEIR
UBERON:0001134skeletal muscle tissue
  • UBERON:0000104life cycle
  • UBERON:0007222late adult stage
2.21e3
  • 2.21e3
  • 4.77e3
90.14
  • 90.14
  • 78.69
AEIR
  • AEIR
  • AEIR
UBERON:0001135smooth muscle tissue
  • UBERON:0000104life cycle
2.21e3
  • 2.21e3
90.13
  • 90.13
AEIR
  • AEIR
UBERON:0000082adult mammalian kidney
  • UBERON:0018241prime adult stage
  • UBERON:0000112sexually immature stage
2.37e3
  • 2.37e3
  • 3.43e3
89.39
  • 89.39
  • 84.65
AEIR
  • AEIR
  • AEIR
UBERON:0002080heart right ventricle
  • UBERON:0007222late adult stage
2.41e3
  • 2.41e3
89.24
  • 89.24
AEIR
  • AEIR
UBERON:0001235adrenal cortex
  • UBERON:0018241prime adult stage
2.43e3
  • 2.43e3
89.13
  • 89.13
AEIR
  • AEIR
UBERON:0002370thymus
  • UBERON:0000104life cycle
3.01e3
  • 3.01e3
86.53
  • 86.53
AEIR
  • AEIR
UBERON:0001044saliva-secreting gland
  • UBERON:0007222late adult stage
3.12e3
  • 3.12e3
86.07
  • 86.07
AEIR
  • AEIR
UBERON:0002084heart left ventricle
  • UBERON:0018241prime adult stage
  • UBERON:0007222late adult stage
3.34e3
  • 3.34e3
  • 3.48e3
85.08
  • 85.08
  • 84.44
AEIR
  • AEIR
  • AEIR
UBERON:0002115jejunum
  • UBERON:0000104life cycle
3.88e3
  • 3.88e3
82.67
  • 82.67
AEIR
  • AEIR
UBERON:0002046thyroid gland
  • UBERON:0007222late adult stage
3.94e3
  • 3.94e3
82.40
  • 82.40
AEIR
  • AEIR
UBERON:0001723tongue
  • UBERON:0000113post-juvenile adult stage
4.14e3
  • 4.14e3
81.51
  • 81.51
AEIR
  • AEIR
UBERON:0000033head
  • UBERON:0000112sexually immature stage
4.24e3
  • 4.24e3
81.03
  • 81.03
AEIR
  • AEIR
UBERON:0003382cardiac muscle of left ventricle
  • UBERON:0000104life cycle
7.30e3
  • 7.30e3
67.38
  • 67.38
AEIR
  • AEIR
UBERON:0000178blood
  • UBERON:0000104life cycle
9.16e3
  • 9.16e3
59.03
  • 59.03
AEIR
  • AEIR
Sources
AAffymetrix
EEST
IIn Situ
RRNA-Seq
data
no data
Rank scores
3.25e4lightgrey: low confidence scores

important score variation

Rank scores of expression calls are normalized across genes, conditions and species. Low score means that the gene is highly expressed in the condition. Max rank score in all species: 4.10e4. Min rank score varies across species.

Expression scores of expression calls use the minimum and maximum Rank of the species to normalize the expression to a value between 0 and 100. Low score means that the gene is lowly expressed in the condition.

Sources of annotations to anatomy and development:
  • RNA-Seq data: Bgee
Sources of raw data:
  • RNA-Seq data: GEO

Orthologs

Taxon nameSpecies with orthologsGene(s)Expression comparisonSee details
Carnivora1 species1 geneCompare expression
Laurasiatheria3 species3 genesCompare expression
Boreoeutheria11 species11 genesCompare expression
Amniota13 species13 genesCompare expression
Tetrapoda14 species14 genesCompare expression
Euteleostomi15 species15 genesCompare expression

Orthology information comes from OMA : ENSCAFG00000012556.

Paralogs (same species)

Taxon nameGene(s)Expression comparisonSee details
Eumetazoa2 genesCompare expression

Paralogy information comes from OMA : ENSCAFG00000012556.

Cross-references

EnsemblENSCAFG00000012556 (HTRA1)
HGNCHGNC:9476 (HTRA1)
EMBLAAEX03015605
Uniprot/SPTREMBLF1PU95, F1PU95_CANLF, J9P2L4, J9P2L4_CANLF

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