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C. lupus familiaris Gene: PCSK1N - ENSCAFG00000015657 - Canis lupus familiaris (dog)

General information

Ensembl IDENSCAFG00000015657
NamePCSK1N
Descriptionproprotein convertase subtilisin/kexin type 1 inhibitor [Source:HGNC Symbol;Acc:HGNC:17301]
OrganismCanis lupus familiaris (dog)
Synonym(s)saas, scg8, sgviii
Orthologs(s)11 orthologs

Expression

Anat. entity IDAnatomical entityDevelopmental stage(s)Rank scoreExpression scoreSources
UBERON:0000955brain
  • UBERON:0000104life cycle
  • UBERON:0018241prime adult stage
269
  • 269
  • 1.29e3
98.80
  • 98.80
  • 94.25
AEIR
  • AEIR
  • AEIR
UBERON:0000007pituitary gland
  • UBERON:0018241prime adult stage
  • UBERON:0007222late adult stage
316
  • 316
  • 5.47e3
98.59
  • 98.59
  • 75.56
AEIR
  • AEIR
  • AEIR
UBERON:0001871temporal lobe
  • UBERON:0000113post-juvenile adult stage
342
  • 342
98.47
  • 98.47
AEIR
  • AEIR
UBERON:0002021occipital lobe
  • UBERON:0000113post-juvenile adult stage
375
  • 375
98.33
  • 98.33
AEIR
  • AEIR
UBERON:0000473testis
  • UBERON:0018241prime adult stage
  • UBERON:0000104life cycle
669
  • 669
  • 1.19e4
97.01
  • 97.01
  • 47.00
AEIR
  • AEIR
  • AEIR
UBERON:0000451prefrontal cortex
  • UBERON:0018241prime adult stage
877
  • 877
96.08
  • 96.08
AEIR
  • AEIR
UBERON:0001235adrenal cortex
  • UBERON:0018241prime adult stage
1.38e3
  • 1.38e3
93.82
  • 93.82
AEIR
  • AEIR
UBERON:0001870frontal cortex
  • UBERON:0007222late adult stage
1.44e3
  • 1.44e3
93.59
  • 93.59
AEIR
  • AEIR
UBERON:0002264olfactory bulb
  • UBERON:0000104life cycle
1.85e3
  • 1.85e3
91.72
  • 91.72
AEIR
  • AEIR
UBERON:0001264pancreas
  • UBERON:0000113post-juvenile adult stage
  • UBERON:0007222late adult stage
  • UBERON:0000104life cycle
2.17e3
  • 2.17e3
  • 7.64e3
  • 9.83e3
90.28
  • 90.28
  • 65.86
  • 56.06
AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0002135mitral valve
  • UBERON:0007222late adult stage
  • UBERON:0018241prime adult stage
2.77e3
  • 2.77e3
  • 4.86e3
87.63
  • 87.63
  • 78.29
AEIR
  • AEIR
  • AEIR
UBERON:0002240spinal cord
  • UBERON:0000104life cycle
4.22e3
  • 4.22e3
81.12
  • 81.12
AEIR
  • AEIR
UBERON:0002037cerebellum
  • UBERON:0000104life cycle
  • UBERON:0007222late adult stage
4.86e3
  • 4.86e3
  • 1.10e4
78.25
  • 78.25
  • 50.61
AEIR
  • AEIR
  • AEIR
UBERON:0000992female gonad
  • UBERON:0000104life cycle
7.08e3
  • 7.08e3
68.36
  • 68.36
AEIR
  • AEIR
UBERON:0002369adrenal gland
  • UBERON:0007222late adult stage
  • UBERON:0000104life cycle
7.20e3
  • 7.20e3
  • 9.06e3
67.80
  • 67.80
  • 59.50
AEIR
  • AEIR
  • AEIR
UBERON:0001898hypothalamus
  • UBERON:0000104life cycle
7.30e3
  • 7.30e3
67.34
  • 67.34
AEIR
  • AEIR
UBERON:0001723tongue
  • UBERON:0000113post-juvenile adult stage
7.69e3
  • 7.69e3
65.61
  • 65.61
AEIR
  • AEIR
UBERON:0001911mammary gland
  • UBERON:0018241prime adult stage
  • UBERON:0000104life cycle
8.04e3
  • 8.04e3
  • 1.49e4
64.04
  • 64.04
  • 33.51
AEIR
  • AEIR
  • AEIR
UBERON:0002046thyroid gland
  • UBERON:0007222late adult stage
9.08e3
  • 9.08e3
59.41
  • 59.41
AEIR
  • AEIR
UBERON:0000966retina
  • UBERON:0000104life cycle
9.13e3
  • 9.13e3
59.18
  • 59.18
AEIR
  • AEIR
UBERON:0016540occipital cortex
  • UBERON:0007222late adult stage
9.94e3
  • 9.94e3
55.56
  • 55.56
AEIR
  • AEIR
UBERON:0002113kidney
  • UBERON:0000104life cycle
1.00e4
  • 1.00e4
55.07
  • 55.07
AEIR
  • AEIR
UBERON:0002107liver
  • UBERON:0000113post-juvenile adult stage
  • UBERON:0000104life cycle
  • UBERON:0000112sexually immature stage
1.04e4
  • 1.04e4
  • 1.39e4
  • 1.68e4
53.55
  • 53.55
  • 37.69
  • 24.75
AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0000082adult mammalian kidney
  • UBERON:0018241prime adult stage
  • UBERON:0000112sexually immature stage
1.09e4
  • 1.09e4
  • 1.64e4
51.22
  • 51.22
  • 26.67
AEIR
  • AEIR
  • AEIR
UBERON:0000945stomach
  • UBERON:0000113post-juvenile adult stage
  • UBERON:0007222late adult stage
1.10e4
  • 1.10e4
  • 1.42e4
50.62
  • 50.62
  • 36.71
AEIR
  • AEIR
  • AEIR
UBERON:0000059large intestine
  • UBERON:0000113post-juvenile adult stage
1.11e4
  • 1.11e4
50.15
  • 50.15
AEIR
  • AEIR
UBERON:0001134skeletal muscle tissue
  • UBERON:0000104life cycle
1.12e4
  • 1.12e4
50.14
  • 50.14
AEIR
  • AEIR
UBERON:0001135smooth muscle tissue
  • UBERON:0000104life cycle
1.13e4
  • 1.13e4
49.54
  • 49.54
AEIR
  • AEIR
UBERON:0002084heart left ventricle
  • UBERON:0018241prime adult stage
  • UBERON:0007222late adult stage
1.15e4
  • 1.15e4
  • 1.36e4
48.79
  • 48.79
  • 39.26
AEIR
  • AEIR
  • AEIR
UBERON:0000948heart
  • UBERON:0000104life cycle
  • UBERON:0000112sexually immature stage
1.15e4
  • 1.15e4
  • 1.66e4
48.36
  • 48.36
  • 25.57
AEIR
  • AEIR
  • AEIR
UBERON:0002048lung
  • UBERON:0000104life cycle
  • UBERON:0007222late adult stage
  • UBERON:0000112sexually immature stage
1.16e4
  • 1.16e4
  • 1.53e4
  • 1.72e4
48.09
  • 48.09
  • 31.58
  • 22.87
AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0002108small intestine
  • UBERON:0000113post-juvenile adult stage
  • UBERON:0007222late adult stage
1.16e4
  • 1.16e4
  • 1.27e4
47.98
  • 47.98
  • 43.40
AEIR
  • AEIR
  • AEIR
UBERON:0000033head
  • UBERON:0000112sexually immature stage
1.22e4
  • 1.22e4
45.67
  • 45.67
AEIR
  • AEIR
UBERON:0002106spleen
  • UBERON:0007222late adult stage
  • UBERON:0000113post-juvenile adult stage
  • UBERON:0000104life cycle
1.22e4
  • 1.22e4
  • 1.35e4
  • 1.50e4
45.64
  • 45.64
  • 39.66
  • 33.05
AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0002115jejunum
  • UBERON:0000104life cycle
1.22e4
  • 1.22e4
45.23
  • 45.23
AEIR
  • AEIR
UBERON:0000004nose
  • UBERON:0000104life cycle
1.24e4
  • 1.24e4
44.72
  • 44.72
AEIR
  • AEIR
UBERON:0000362renal medulla
  • UBERON:0007222late adult stage
1.31e4
  • 1.31e4
41.58
  • 41.58
AEIR
  • AEIR
UBERON:0000178blood
  • UBERON:0000104life cycle
1.34e4
  • 1.34e4
40.15
  • 40.15
AEIR
  • AEIR
UBERON:0001155colon
  • UBERON:0000104life cycle
  • UBERON:0007222late adult stage
1.35e4
  • 1.35e4
  • 1.38e4
39.83
  • 39.83
  • 38.28
AEIR
  • AEIR
  • AEIR
UBERON:0000014zone of skin
  • UBERON:0007222late adult stage
  • UBERON:0000104life cycle
1.38e4
  • 1.38e4
  • 1.54e4
38.08
  • 38.08
  • 31.05
AEIR
  • AEIR
  • AEIR
UBERON:0002078right cardiac atrium
  • UBERON:0007222late adult stage
1.40e4
  • 1.40e4
37.30
  • 37.30
AEIR
  • AEIR
UBERON:0001255urinary bladder
  • UBERON:0007222late adult stage
1.45e4
  • 1.45e4
35.32
  • 35.32
AEIR
  • AEIR
UBERON:0002418cartilage tissue
  • UBERON:0007222late adult stage
1.46e4
  • 1.46e4
34.72
  • 34.72
AEIR
  • AEIR
UBERON:0001987placenta
  • UBERON:0000113post-juvenile adult stage
1.48e4
  • 1.48e4
33.92
  • 33.92
AEIR
  • AEIR
UBERON:0000029lymph node
  • UBERON:0007222late adult stage
  • UBERON:0000104life cycle
1.48e4
  • 1.48e4
  • 1.84e4
33.87
  • 33.87
  • 17.58
AEIR
  • AEIR
  • AEIR
UBERON:0002073hair follicle
  • UBERON:0000104life cycle
1.48e4
  • 1.48e4
33.74
  • 33.74
AEIR
  • AEIR
UBERON:0002080heart right ventricle
  • UBERON:0007222late adult stage
1.49e4
  • 1.49e4
33.48
  • 33.48
AEIR
  • AEIR
UBERON:0010533metanephros cortex
  • UBERON:0007222late adult stage
1.49e4
  • 1.49e4
33.20
  • 33.20
AEIR
  • AEIR
UBERON:0001044saliva-secreting gland
  • UBERON:0007222late adult stage
1.50e4
  • 1.50e4
33.02
  • 33.02
AEIR
  • AEIR
Sources
AAffymetrix
EEST
IIn Situ
RRNA-Seq
data
no data
Rank scores
3.25e4lightgrey: low confidence scores

important score variation

Rank scores of expression calls are normalized across genes, conditions and species. Low score means that the gene is highly expressed in the condition. Max rank score in all species: 4.10e4. Min rank score varies across species.

Expression scores of expression calls use the minimum and maximum Rank of the species to normalize the expression to a value between 0 and 100. Low score means that the gene is lowly expressed in the condition.

Sources of annotations to anatomy and development:
  • RNA-Seq data: Bgee
Sources of raw data:
  • RNA-Seq data: GEO

Orthologs

Cross-references

EnsemblENSCAFG00000015657 (PCSK1N)
HGNCHGNC:17301 (PCSK1N)
EMBLAAEX03026338
Uniprot/SPTREMBLE2RIQ3, E2RIQ3_CANLF

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