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C. lupus familiaris Gene: ARHGEF2 - ENSCAFG00000016889 - Canis lupus familiaris (dog)

General information

Ensembl IDENSCAFG00000016889
NameARHGEF2
Descriptionrho guanine nucleotide exchange factor 2 isoform A [Source:RefSeq peptide;Acc:NP_001002995]
OrganismCanis lupus familiaris (dog)
Synonym(s)gef-h1, gef-h1/lfc
Orthologs(s)16 orthologs

Expression

Anat. entity IDAnatomical entityDevelopmental stage(s)Rank scoreExpression scoreSources
UBERON:0002037cerebellum
  • UBERON:0000104life cycle
  • UBERON:0007222late adult stage
1.20e3
  • 1.20e3
  • 1.95e3
94.62
  • 94.62
  • 91.28
AEIR
  • AEIR
  • AEIR
CL:0000094granulocyte
  • UBERON:0000104life cycle
1.35e3
  • 1.35e3
93.95
  • 93.95
AEIR
  • AEIR
UBERON:0000451prefrontal cortex
  • UBERON:0018241prime adult stage
1.57e3
  • 1.57e3
93.00
  • 93.00
AEIR
  • AEIR
UBERON:0002021occipital lobe
  • UBERON:0000113post-juvenile adult stage
1.87e3
  • 1.87e3
91.66
  • 91.66
AEIR
  • AEIR
UBERON:0001871temporal lobe
  • UBERON:0000113post-juvenile adult stage
1.89e3
  • 1.89e3
91.56
  • 91.56
AEIR
  • AEIR
UBERON:0002048lung
  • UBERON:0000104life cycle
  • UBERON:0000112sexually immature stage
  • UBERON:0007222late adult stage
1.93e3
  • 1.93e3
  • 2.65e3
  • 2.86e3
91.37
  • 91.37
  • 88.15
  • 87.21
AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0001898hypothalamus
  • UBERON:0000104life cycle
1.96e3
  • 1.96e3
91.23
  • 91.23
AEIR
  • AEIR
UBERON:0000178blood
  • UBERON:0000104life cycle
2.01e3
  • 2.01e3
91.00
  • 91.00
AEIR
  • AEIR
UBERON:0001870frontal cortex
  • UBERON:0007222late adult stage
2.14e3
  • 2.14e3
90.43
  • 90.43
AEIR
  • AEIR
UBERON:0002106spleen
  • UBERON:0000104life cycle
  • UBERON:0000113post-juvenile adult stage
  • UBERON:0007222late adult stage
2.32e3
  • 2.32e3
  • 2.92e3
  • 3.84e3
89.62
  • 89.62
  • 86.94
  • 82.84
AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0002108small intestine
  • UBERON:0000113post-juvenile adult stage
  • UBERON:0007222late adult stage
2.55e3
  • 2.55e3
  • 5.27e3
88.60
  • 88.60
  • 76.43
AEIR
  • AEIR
  • AEIR
UBERON:0000059large intestine
  • UBERON:0000113post-juvenile adult stage
2.61e3
  • 2.61e3
88.32
  • 88.32
AEIR
  • AEIR
UBERON:0002264olfactory bulb
  • UBERON:0000104life cycle
2.79e3
  • 2.79e3
87.54
  • 87.54
AEIR
  • AEIR
UBERON:0002370thymus
  • UBERON:0000104life cycle
2.83e3
  • 2.83e3
87.37
  • 87.37
AEIR
  • AEIR
UBERON:0002240spinal cord
  • UBERON:0000104life cycle
2.89e3
  • 2.89e3
87.10
  • 87.10
AEIR
  • AEIR
UBERON:0016540occipital cortex
  • UBERON:0007222late adult stage
2.90e3
  • 2.90e3
87.02
  • 87.02
AEIR
  • AEIR
UBERON:0000948heart
  • UBERON:0000104life cycle
  • UBERON:0000112sexually immature stage
2.93e3
  • 2.93e3
  • 3.62e3
86.90
  • 86.90
  • 83.81
AEIR
  • AEIR
  • AEIR
UBERON:0001155colon
  • UBERON:0000104life cycle
  • UBERON:0007222late adult stage
2.98e3
  • 2.98e3
  • 5.50e3
86.66
  • 86.66
  • 75.43
AEIR
  • AEIR
  • AEIR
UBERON:0001911mammary gland
  • UBERON:0018241prime adult stage
  • UBERON:0000104life cycle
3.17e3
  • 3.17e3
  • 5.19e3
85.82
  • 85.82
  • 76.80
AEIR
  • AEIR
  • AEIR
UBERON:0002418cartilage tissue
  • UBERON:0007222late adult stage
3.32e3
  • 3.32e3
85.17
  • 85.17
AEIR
  • AEIR
UBERON:0000029lymph node
  • UBERON:0007222late adult stage
  • UBERON:0000104life cycle
3.41e3
  • 3.41e3
  • 8.55e3
84.78
  • 84.78
  • 61.76
AEIR
  • AEIR
  • AEIR
UBERON:0002371bone marrow
  • UBERON:0007222late adult stage
3.42e3
  • 3.42e3
84.72
  • 84.72
AEIR
  • AEIR
UBERON:0000966retina
  • UBERON:0000104life cycle
3.43e3
  • 3.43e3
84.68
  • 84.68
AEIR
  • AEIR
UBERON:0000945stomach
  • UBERON:0007222late adult stage
  • UBERON:0000113post-juvenile adult stage
3.43e3
  • 3.43e3
  • 4.73e3
84.65
  • 84.65
  • 78.86
AEIR
  • AEIR
  • AEIR
UBERON:0002135mitral valve
  • UBERON:0018241prime adult stage
  • UBERON:0007222late adult stage
3.45e3
  • 3.45e3
  • 3.70e3
84.58
  • 84.58
  • 83.46
AEIR
  • AEIR
  • AEIR
UBERON:0002084heart left ventricle
  • UBERON:0007222late adult stage
  • UBERON:0018241prime adult stage
3.54e3
  • 3.54e3
  • 3.64e3
84.19
  • 84.19
  • 83.71
AEIR
  • AEIR
  • AEIR
UBERON:0000033head
  • UBERON:0000112sexually immature stage
3.61e3
  • 3.61e3
83.88
  • 83.88
AEIR
  • AEIR
UBERON:0003382cardiac muscle of left ventricle
  • UBERON:0000104life cycle
3.74e3
  • 3.74e3
83.28
  • 83.28
AEIR
  • AEIR
UBERON:0002115jejunum
  • UBERON:0000104life cycle
3.93e3
  • 3.93e3
82.44
  • 82.44
AEIR
  • AEIR
UBERON:0002080heart right ventricle
  • UBERON:0007222late adult stage
4.25e3
  • 4.25e3
80.99
  • 80.99
AEIR
  • AEIR
UBERON:0000014zone of skin
  • UBERON:0007222late adult stage
  • UBERON:0000104life cycle
4.32e3
  • 4.32e3
  • 9.47e3
80.67
  • 80.67
  • 57.64
AEIR
  • AEIR
  • AEIR
UBERON:0000082adult mammalian kidney
  • UBERON:0000112sexually immature stage
  • UBERON:0018241prime adult stage
4.45e3
  • 4.45e3
  • 1.06e4
80.10
  • 80.10
  • 52.72
AEIR
  • AEIR
  • AEIR
UBERON:0001013adipose tissue
  • UBERON:0007222late adult stage
4.73e3
  • 4.73e3
78.86
  • 78.86
AEIR
  • AEIR
UBERON:0000007pituitary gland
  • UBERON:0018241prime adult stage
  • UBERON:0007222late adult stage
4.74e3
  • 4.74e3
  • 7.29e3
78.80
  • 78.80
  • 67.39
AEIR
  • AEIR
  • AEIR
UBERON:0001134skeletal muscle tissue
  • UBERON:0000104life cycle
  • UBERON:0007222late adult stage
4.96e3
  • 4.96e3
  • 8.51e3
77.82
  • 77.82
  • 61.93
AEIR
  • AEIR
  • AEIR
UBERON:0001135smooth muscle tissue
  • UBERON:0000104life cycle
4.98e3
  • 4.98e3
77.76
  • 77.76
AEIR
  • AEIR
UBERON:0000992female gonad
  • UBERON:0000104life cycle
5.00e3
  • 5.00e3
77.66
  • 77.66
AEIR
  • AEIR
UBERON:0002078right cardiac atrium
  • UBERON:0007222late adult stage
5.07e3
  • 5.07e3
77.31
  • 77.31
AEIR
  • AEIR
UBERON:0001723tongue
  • UBERON:0000113post-juvenile adult stage
5.26e3
  • 5.26e3
76.48
  • 76.48
AEIR
  • AEIR
UBERON:0001259mucosa of urinary bladder
  • UBERON:0000104life cycle
5.63e3
  • 5.63e3
74.81
  • 74.81
AEIR
  • AEIR
UBERON:0002046thyroid gland
  • UBERON:0007222late adult stage
6.32e3
  • 6.32e3
71.74
  • 71.74
AEIR
  • AEIR
UBERON:0002369adrenal gland
  • UBERON:0000104life cycle
  • UBERON:0007222late adult stage
6.45e3
  • 6.45e3
  • 7.96e3
71.15
  • 71.15
  • 64.40
AEIR
  • AEIR
  • AEIR
CL:0000312keratinocyte
  • UBERON:0000104life cycle
6.51e3
  • 6.51e3
70.88
  • 70.88
AEIR
  • AEIR
UBERON:0002107liver
  • UBERON:0000112sexually immature stage
  • UBERON:0000113post-juvenile adult stage
  • UBERON:0018241prime adult stage
  • UBERON:0000104life cycle
  • UBERON:0007222late adult stage
6.62e3
  • 6.62e3
  • 7.00e3
  • 7.02e3
  • 7.08e3
  • 7.95e3
70.41
  • 70.41
  • 68.71
  • 68.63
  • 68.33
  • 64.44
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0001255urinary bladder
  • UBERON:0007222late adult stage
6.82e3
  • 6.82e3
69.50
  • 69.50
AEIR
  • AEIR
UBERON:0001264pancreas
  • UBERON:0007222late adult stage
  • UBERON:0000113post-juvenile adult stage
  • UBERON:0000104life cycle
6.85e3
  • 6.85e3
  • 7.42e3
  • 8.45e3
69.37
  • 69.37
  • 66.83
  • 62.22
AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0000473testis
  • UBERON:0000104life cycle
6.86e3
  • 6.86e3
69.33
  • 69.33
AEIR
  • AEIR
UBERON:0001044saliva-secreting gland
  • UBERON:0007222late adult stage
7.39e3
  • 7.39e3
66.98
  • 66.98
AEIR
  • AEIR
UBERON:0002073hair follicle
  • UBERON:0000104life cycle
7.89e3
  • 7.89e3
64.72
  • 64.72
AEIR
  • AEIR
UBERON:0001235adrenal cortex
  • UBERON:0018241prime adult stage
8.14e3
  • 8.14e3
63.60
  • 63.60
AEIR
  • AEIR
UBERON:0000362renal medulla
  • UBERON:0007222late adult stage
8.25e3
  • 8.25e3
63.12
  • 63.12
AEIR
  • AEIR
UBERON:0010533metanephros cortex
  • UBERON:0007222late adult stage
8.41e3
  • 8.41e3
62.40
  • 62.40
AEIR
  • AEIR
UBERON:0001987placenta
  • UBERON:0000113post-juvenile adult stage
8.72e3
  • 8.72e3
61.02
  • 61.02
AEIR
  • AEIR
UBERON:0000004nose
  • UBERON:0000104life cycle
9.45e3
  • 9.45e3
57.75
  • 57.75
AEIR
  • AEIR
Sources
AAffymetrix
EEST
IIn Situ
RRNA-Seq
data
no data
Rank scores
3.25e4lightgrey: low confidence scores

important score variation

Rank scores of expression calls are normalized across genes, conditions and species. Low score means that the gene is highly expressed in the condition. Max rank score in all species: 4.10e4. Min rank score varies across species.

Expression scores of expression calls use the minimum and maximum Rank of the species to normalize the expression to a value between 0 and 100. Low score means that the gene is lowly expressed in the condition.

Sources of annotations to anatomy and development:
  • RNA-Seq data: Bgee
Sources of raw data:
  • RNA-Seq data: GEO

Orthologs

Taxon nameSpecies with orthologsGene(s)Expression comparisonSee details
Carnivora1 species1 geneCompare expression
Laurasiatheria5 species5 genesCompare expression
Boreoeutheria13 species13 genesCompare expression
Theria14 species14 genesCompare expression
Euteleostomi15 species16 genesCompare expression

Orthology information comes from OMA : ENSCAFG00000016889.

Cross-references

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