Gene: ctsll - ENSDARG00000011701 - Danio rerio (zebrafish)

General information

Ensembl ID	ENSDARG00000011701
Name	ctsll
Description	cathepsin L, like [Source:ZFIN;Acc:ZDB-GENE-041010-76]
Organism	Danio rerio (zebrafish)
Synonym(s)	zgc:101557
Orthologs(s)	38 orthologs
Paralog(s)	24 paralogs

Expression

Anat. entity ID	Anatomical entity	Developmental stage(s)	Rank score	Expression score	Sources
UBERON:0004734	gastrula	[+] 6 stages ZFS:0000022Gastrula:Bud ZFS:0000019Gastrula:Shield ZFS:0000021Gastrula:90%-epiboly ZFS:0000020Gastrula:75%-epiboly ZFS:0000017Gastrula:50%-epiboly UBERON:0000109gastrula stage	237 237 296 531 613 616 1.46e3	99.21 99.21 99.01 98.23 97.95 97.94 95.12	AEIR AEIR AEIR AEIR AEIR AEIR AEIR
UBERON:0000468	multi-cellular organism	[+] 13 stages ZFS:0000024Segmentation:5-9 somites ZFS:0000022Gastrula:Bud ZFS:0000020Gastrula:75%-epiboly ZFS:0000021Gastrula:90%-epiboly ZFS:0000019Gastrula:Shield ZFS:0000026Segmentation:14-19 somites ZFS:0000029Pharyngula:Prim-5 ZFS:0000030Pharyngula:Prim-15 ZFS:0000033Hatching:Long-pec UBERON:0000068embryo stage ZFS:0000049segmentation ZFS:0000037Larval:Day 5 ZFS:0000036Larval:Day 4	601 601 647 662 688 1.07e3 2.93e3 4.75e3 6.19e3 1.24e4 1.31e4 1.49e4 1.83e4 1.83e4	97.99 97.99 97.84 97.79 97.70 96.42 90.19 84.09 79.29 58.57 56.27 49.95 38.62 38.57	AEIR AEIR AEIR AEIR AEIR AEIR AEIR AEIR AEIR AEIR AEIR AEIR AEIR AEIR
UBERON:0000922	embryo	[+] 10 stages ZFS:0000025Segmentation:10-13 somites ZFS:0000024Segmentation:5-9 somites ZFS:0000026Segmentation:14-19 somites ZFS:0000029Pharyngula:Prim-5 UBERON:0000068embryo stage UBERON:0004707pharyngula stage ZFS:0000030Pharyngula:Prim-15 ZFS:0000031Pharyngula:Prim-25 ZFS:0000033Hatching:Long-pec ZFS:0000037Larval:Day 5	696 696 895 930 1.56e3 1.72e3 1.82e3 2.22e3 1.11e4 1.66e4 2.19e4	97.67 97.67 97.01 96.89 94.77 94.24 93.89 92.57 62.81 44.28 26.77	AEIR AEIR AEIR AEIR AEIR AEIR AEIR AEIR AEIR AEIR AEIR
UBERON:0000307	blastula	[+] 2 stages ZFS:0000015Blastula:Dome ZFS:0000016Blastula:30%-epiboly	1.37e3 1.37e3 4.52e3	95.42 95.42 84.85	AEIR AEIR AEIR
UBERON:0000955	brain	[+] 2 stages ZFS:0000031Pharyngula:Prim-25 UBERON:0000066fully formed stage	9.18e3 9.18e3 1.91e4	69.28 69.28 35.97	AEIR AEIR AEIR
UBERON:0000948	heart	[+] 2 stages UBERON:0000066fully formed stage ZFS:0000036Larval:Day 4	1.16e4 1.16e4 1.22e4	61.06 61.06 59.02	AEIR AEIR AEIR
UBERON:0000206	pharyngeal gill	[+] 1 stage UBERON:0000066fully formed stage	1.41e4 1.41e4	52.84 52.84	AEIR AEIR
UBERON:0019248	early embryo	[+] 1 stage UBERON:0000107cleavage stage	1.44e4 1.44e4	51.83 51.83	AEIR AEIR
CL:0000094	granulocyte	[+] 1 stage UBERON:0000066fully formed stage	1.49e4 1.49e4	50.22 50.22	AEIR AEIR
UBERON:0009620	tail bud paraxial mesoderm	[+] 1 stage ZFS:0000027Segmentation:20-25 somites	1.51e4 1.51e4	49.60 49.60	AEIR AEIR
UBERON:0002548	larva	[+] 2 stages UBERON:0000069larval stage ZFS:0000037Larval:Day 5	1.51e4 1.51e4 1.93e4	49.53 49.53 35.44	AEIR AEIR AEIR
UBERON:0000160	intestine	[+] 1 stage UBERON:0000066fully formed stage	1.58e4 1.58e4	47.16 47.16	AEIR AEIR
UBERON:0002385	muscle tissue	[+] 1 stage UBERON:0000066fully formed stage	1.63e4 1.63e4	45.29 45.29	AEIR AEIR
UBERON:0002199	integument	[+] 1 stage UBERON:0000066fully formed stage	1.77e4 1.77e4	40.77 40.77	AEIR AEIR
UBERON:0007132	head kidney	[+] 1 stage UBERON:0000066fully formed stage	1.84e4 1.84e4	38.54 38.54	AEIR AEIR
UBERON:0002106	spleen	[+] 1 stage UBERON:0000066fully formed stage	1.84e4 1.84e4	38.48 38.48	AEIR AEIR
UBERON:0001630	muscle organ	[+] 1 stage UBERON:0000066fully formed stage	1.96e4 1.96e4	34.41 34.41	AEIR AEIR
UBERON:0000014	zone of skin	[+] 1 stage UBERON:0000066fully formed stage	2.08e4 2.08e4	30.24 30.24	AEIR AEIR
UBERON:0000033	head	[+] 1 stage UBERON:0000066fully formed stage	2.12e4 2.12e4	29.08 29.08	AEIR AEIR
UBERON:0002481	bone tissue	[+] 1 stage UBERON:0000066fully formed stage	2.23e4 2.23e4	25.45 25.45	AEIR AEIR

Sources
A	Affymetrix
E	EST
I	In Situ
R	RNA-Seq

data

no data

Rank scores
3.25e4	lightgrey: low confidence scores
	important score variation

Rank scores of expression calls are normalized across genes, conditions and species. Low score means that the gene is highly expressed in the condition. Max rank score in all species: 4.10e4. Min rank score varies across species.

Expression scores of expression calls use the minimum and maximum Rank of the species to normalize the expression to a value between 0 and 100. Low score means that the gene is lowly expressed in the condition.

Sources of annotations to anatomy and development:

Affymetrix data: Bgee
EST data: Bgee
RNA-Seq data: Bgee

Sources of raw data:

Affymetrix data: ArrayExpress, GEO
EST data: UniGene
RNA-Seq data: GEO

Orthologs

Taxon name	Species with orthologs	Gene(s)	Expression comparison	See details
Euteleostomi	16 species Homo sapiens (human) Pan troglodytes (chimpanzee) Gorilla gorilla (gorilla) Macaca mulatta (macaque) Bos taurus (cattle) Sus scrofa (pig) Equus caballus (horse) Oryctolagus cuniculus (rabbit) Canis lupus familiaris (dog) Felis catus (cat) Erinaceus europaeus (hedgehog) Monodelphis domestica (opossum) Ornithorhynchus anatinus (platypus) Gallus gallus (chicken) Anolis carolinensis (green anole) Xenopus tropicalis (western clawed frog)	37 genes ENSG00000135047 CTSL ENSG00000136943 CTSV ENSPTRG00000002675 CTSV ENSPTRG00000021080 CTSL ENSGGOG00000000088 ENSGGOG00000024642 CTSV ENSGGOG00000027208 CTSL ENSMMUG00000013861 ENSMMUG00000017609 CTSL ENSMMUG00000022971 CTSV ENSBTAG00000000720 CTSL ENSBTAG00000017077 CTSL2 ENSSSCG00000010948 CTSL ENSSSCG00000011171 CTSV ENSECAG00000004288 CTSV ENSECAG00000007210 CTSL ENSOCUG00000008397 CTSV ENSOCUG00000017008 ENSOCUG00000017854 ENSOCUG00000029172 ENSCAFG00000001309 CTSL ENSCAFG00000008121 ENSCAFG00000015024 ENSFCAG00000001764 ENSFCAG00000005706 ENSFCAG00000018798 ENSFCAG00000026329 CTSV ENSFCAG00000026406 ENSFCAG00000027621 ENSEEUG00000000812 CTSV ENSEEUG00000004277 CTSL ENSMODG00000002844 ENSOANG00000000189 ENSOANG00000000217 ENSGALG00000012610 CTSL2 ENSACAG00000013328 ENSXETG00000027581 ctsv	Compare expression	[+]
Bilateria	17 species Homo sapiens (human) Caenorhabditis elegans (nematode) Pan troglodytes (chimpanzee) Gorilla gorilla (gorilla) Macaca mulatta (macaque) Bos taurus (cattle) Sus scrofa (pig) Equus caballus (horse) Oryctolagus cuniculus (rabbit) Canis lupus familiaris (dog) Felis catus (cat) Erinaceus europaeus (hedgehog) Monodelphis domestica (opossum) Ornithorhynchus anatinus (platypus) Gallus gallus (chicken) Anolis carolinensis (green anole) Xenopus tropicalis (western clawed frog)	38 genes ENSG00000135047 CTSL ENSG00000136943 CTSV WBGene00000776 cpl-1 ENSPTRG00000002675 CTSV ENSPTRG00000021080 CTSL ENSGGOG00000000088 ENSGGOG00000024642 CTSV ENSGGOG00000027208 CTSL ENSMMUG00000013861 ENSMMUG00000017609 CTSL ENSMMUG00000022971 CTSV ENSBTAG00000000720 CTSL ENSBTAG00000017077 CTSL2 ENSSSCG00000010948 CTSL ENSSSCG00000011171 CTSV ENSECAG00000004288 CTSV ENSECAG00000007210 CTSL ENSOCUG00000008397 CTSV ENSOCUG00000017008 ENSOCUG00000017854 ENSOCUG00000029172 ENSCAFG00000001309 CTSL ENSCAFG00000008121 ENSCAFG00000015024 ENSFCAG00000001764 ENSFCAG00000005706 ENSFCAG00000018798 ENSFCAG00000026329 CTSV ENSFCAG00000026406 ENSFCAG00000027621 ENSEEUG00000000812 CTSV ENSEEUG00000004277 CTSL ENSMODG00000002844 ENSOANG00000000189 ENSOANG00000000217 ENSGALG00000012610 CTSL2 ENSACAG00000013328 ENSXETG00000027581 ctsv	Compare expression	[+]

Orthology information comes from OMA : ENSDARG00000011701.

Paralogs (same species)

Taxon name	Gene(s)	Expression comparison	See details
Clupeocephala	1 gene ENSDARG00000007836 ctsla	Compare expression	[+]
Vertebrata	13 genes ENSDARG00000007836 ctsla ENSDARG00000039173 ctslb ENSDARG00000074306 ctslb ENSDARG00000075527 si:dkey-269i1.3 ENSDARG00000079376 zgc:174153 ENSDARG00000087651 si:dkey-26g8.4 ENSDARG00000089750 si:dkey-26g8.5 ENSDARG00000089806 si:dkey-239j18.3 ENSDARG00000094559 zgc:174855 ENSDARG00000095072 si:dkey-26g8.4 ENSDARG00000095254 si:dkey-239j18.2 ENSDARG00000095744 si:dkey-269i1.4 ENSDARG00000100833 si:dkey-269i1.4	Compare expression	[+]
Deuterostomia	14 genes ENSDARG00000003902 ctsl.1 ENSDARG00000007836 ctsla ENSDARG00000039173 ctslb ENSDARG00000074306 ctslb ENSDARG00000075527 si:dkey-269i1.3 ENSDARG00000079376 zgc:174153 ENSDARG00000087651 si:dkey-26g8.4 ENSDARG00000089750 si:dkey-26g8.5 ENSDARG00000089806 si:dkey-239j18.3 ENSDARG00000094559 zgc:174855 ENSDARG00000095072 si:dkey-26g8.4 ENSDARG00000095254 si:dkey-239j18.2 ENSDARG00000095744 si:dkey-269i1.4 ENSDARG00000100833 si:dkey-269i1.4	Compare expression	[+]
Bilateria	16 genes ENSDARG00000003902 ctsl.1 ENSDARG00000007836 ctsla ENSDARG00000036940 ctss1 ENSDARG00000039173 ctslb ENSDARG00000040251 ctsk ENSDARG00000074306 ctslb ENSDARG00000075527 si:dkey-269i1.3 ENSDARG00000079376 zgc:174153 ENSDARG00000087651 si:dkey-26g8.4 ENSDARG00000089750 si:dkey-26g8.5 ENSDARG00000089806 si:dkey-239j18.3 ENSDARG00000094559 zgc:174855 ENSDARG00000095072 si:dkey-26g8.4 ENSDARG00000095254 si:dkey-239j18.2 ENSDARG00000095744 si:dkey-269i1.4 ENSDARG00000100833 si:dkey-269i1.4	Compare expression	[+]
Opisthokonta	18 genes ENSDARG00000003902 ctsl.1 ENSDARG00000007836 ctsla ENSDARG00000013771 ctss2.2 ENSDARG00000036940 ctss1 ENSDARG00000039173 ctslb ENSDARG00000040251 ctsk ENSDARG00000074306 ctslb ENSDARG00000074656 ctss2.1 ENSDARG00000075527 si:dkey-269i1.3 ENSDARG00000079376 zgc:174153 ENSDARG00000087651 si:dkey-26g8.4 ENSDARG00000089750 si:dkey-26g8.5 ENSDARG00000089806 si:dkey-239j18.3 ENSDARG00000094559 zgc:174855 ENSDARG00000095072 si:dkey-26g8.4 ENSDARG00000095254 si:dkey-239j18.2 ENSDARG00000095744 si:dkey-269i1.4 ENSDARG00000100833 si:dkey-269i1.4	Compare expression	[+]
Eukaryota	24 genes ENSDARG00000003902 ctsl.1 ENSDARG00000007836 ctsla ENSDARG00000013771 ctss2.2 ENSDARG00000036940 ctss1 ENSDARG00000039173 ctslb ENSDARG00000040251 ctsk ENSDARG00000041108 ctsh ENSDARG00000042753 cts12 ENSDARG00000043081 ctsz ENSDARG00000055120 ctsba ENSDARG00000074306 ctslb ENSDARG00000074656 ctss2.1 ENSDARG00000075527 si:dkey-269i1.3 ENSDARG00000079376 zgc:174153 ENSDARG00000087651 si:dkey-26g8.4 ENSDARG00000089750 si:dkey-26g8.5 ENSDARG00000089806 si:dkey-239j18.3 ENSDARG00000094559 zgc:174855 ENSDARG00000095072 si:dkey-26g8.4 ENSDARG00000095254 si:dkey-239j18.2 ENSDARG00000095744 si:dkey-269i1.4 ENSDARG00000099376 CABZ01050249.1 ENSDARG00000100833 si:dkey-269i1.4 ENSDARG00000101051 ctsbb	Compare expression	[+]

Paralogy information comes from OMA : ENSDARG00000011701.

Cross-references

Ensembl	ENSDARG00000011701 (ctsll)
ZFIN	ZDB-GENE-041010-76 (ctsll)
EMBL	BX119902
Uniprot/SPTREMBL	A2BEM8, A2BEM8_DANRE