Gene: rfx2 - ENSDARG00000013575 - Danio rerio (zebrafish)

General information

Ensembl ID	ENSDARG00000013575
Name	rfx2
Description	regulatory factor X, 2 (influences HLA class II expression) [Source:ZFIN;Acc:ZDB-GENE-050227-4]
Organism	Danio rerio (zebrafish)
Synonym(s)	cb133, cb7, sb:cb133, sb:cb7, wu:fd20b11, zfx2, zgc:91808

Expression

Anat. entity ID	Anatomical entity	Developmental stage(s)	Rank score	Expression score	Sources
UBERON:0003077	paraxial mesoderm	[+] 1 stage ZFS:0000025Segmentation:10-13 somites	2.23e3 2.23e3	92.46218 92.46218	AEIR AEIR
UBERON:0000473	testis	[+] 1 stage UBERON:0000066fully formed stage	2.99e3 2.99e3	89.89423 89.89423	AEIR AEIR
UBERON:0004734	gastrula	[+] 5 stages UBERON:0000109gastrula stage ZFS:0000017Gastrula:50%-epiboly ZFS:0000021Gastrula:90%-epiboly ZFS:0000020Gastrula:75%-epiboly ZFS:0000022Gastrula:Bud	3.54e3 3.54e3 4.04e3 4.06e3 4.84e3 5.11e3	88.03333 88.03333 86.35550 86.28077 83.63902 82.74280	AEIR AEIR AEIR AEIR AEIR AEIR
UBERON:0000468	multi-cellular organism	[+] 19 stages ZFS:0000026Segmentation:14-19 somites ZFS:0000024Segmentation:5-9 somites ZFS:0000022Gastrula:Bud ZFS:0000020Gastrula:75%-epiboly ZFS:0000019Gastrula:Shield ZFS:0000021Gastrula:90%-epiboly ZFS:0000029Pharyngula:Prim-5 ZFS:0000007Cleavage:64-cell UBERON:0000106zygote stage ZFS:0000030Pharyngula:Prim-15 ZFS:0000033Hatching:Long-pec ZFS:0000037Larval:Day 5 ZFS:0000036Larval:Day 4 ZFS:0000040Larval:Days 14-20 UBERON:0000066fully formed stage UBERON:0000104life cycle UBERON:0000109gastrula stage ZFS:0000049segmentation UBERON:0000068embryo stage	3.59e3 3.59e3 5.05e3 5.23e3 5.65e3 5.67e3 5.70e3 6.37e3 6.73e3 7.27e3 7.32e3 8.65e3 8.79e3 1.05e4 1.31e4 1.38e4 1.42e4 1.48e4 1.48e4 1.49e4	87.85376 87.85376 82.95017 82.31913 80.91120 80.84259 80.72560 78.46691 77.26767 75.42630 75.27059 70.78334 70.29360 64.40028 55.86935 53.30083 51.88136 49.99493 49.94930 49.79382	AEIR AEIR AEIR AEIR AEIR AEIR AEIR AEIR AEIR AEIR AEIR AEIR AEIR AEIR AEIR AEIR AEIR AEIR AEIR AEIR
UBERON:0009620	tail bud paraxial mesoderm	[+] 1 stage ZFS:0000027Segmentation:20-25 somites	3.78e3 3.78e3	87.23063 87.23063	AEIR AEIR
UBERON:0002329	somite	[+] 1 stage ZFS:0000025Segmentation:10-13 somites	4.08e3 4.08e3	86.20676 86.20676	AEIR AEIR
UBERON:0000922	embryo	[+] 10 stages UBERON:0000068embryo stage ZFS:0000024Segmentation:5-9 somites ZFS:0000025Segmentation:10-13 somites UBERON:0004707pharyngula stage ZFS:0000029Pharyngula:Prim-5 ZFS:0000026Segmentation:14-19 somites ZFS:0000031Pharyngula:Prim-25 ZFS:0000030Pharyngula:Prim-15 ZFS:0000033Hatching:Long-pec ZFS:0000037Larval:Day 5	4.09e3 4.09e3 4.16e3 4.28e3 4.40e3 5.04e3 5.29e3 6.58e3 7.52e3 8.77e3 9.83e3	86.17951 86.17951 85.95018 85.52056 85.13511 82.97456 82.11722 77.76422 74.58469 70.34881 66.77900	AEIR AEIR AEIR AEIR AEIR AEIR AEIR AEIR AEIR AEIR AEIR
UBERON:4000164	caudal fin	[+] 2 stages UBERON:0000066fully formed stage ZFS:0000033Hatching:Long-pec	4.32e3 4.32e3 5.35e3	85.39107 85.39107 81.92539	AEIR AEIR AEIR
UBERON:0000307	blastula	[+] 3 stages ZFS:0000016Blastula:30%-epiboly ZFS:0000014Blastula:Sphere ZFS:0000009Blastula:256-cell	4.37e3 4.37e3 9.09e3 9.23e3	85.22867 85.22867 69.28647 68.79898	AEIR AEIR AEIR AEIR
UBERON:0003060	pronephric duct	[+] 7 stages ZFS:0000031Pharyngula:Prim-25 ZFS:0000030Pharyngula:Prim-15 ZFS:0000029Pharyngula:Prim-5 ZFS:0000026Segmentation:14-19 somites ZFS:0000027Segmentation:20-25 somites ZFS:0000028Segmentation:26+ somites ZFS:0000025Segmentation:10-13 somites	4.63e3 4.63e3 5.55e3 5.92e3 7.40e3 7.40e3 9.35e3 1.48e4	84.36993 84.36993 81.24324 79.98986 74.98815 74.98646 68.40414 49.99831	AEIR AEIR AEIR AEIR AEIR AEIR AEIR AEIR
UBERON:0003059	presomitic mesoderm	[+] 1 stage ZFS:0000025Segmentation:10-13 somites	4.71e3 4.71e3	84.08318 84.08318	AEIR AEIR
UBERON:0007010	cleaving embryo	[+] 1 stage ZFS:0000005Cleavage:16-cell	5.29e3 5.29e3	82.13898 82.13898	AEIR AEIR
UBERON:0000992	female gonad	[+] 1 stage UBERON:0000066fully formed stage	6.19e3 6.19e3	79.08481 79.08481	AEIR AEIR
UBERON:0001017	central nervous system	[+] 8 stages ZFS:0000026Segmentation:14-19 somites ZFS:0000027Segmentation:20-25 somites ZFS:0000028Segmentation:26+ somites ZFS:0000029Pharyngula:Prim-5 ZFS:0000032Pharyngula:High-pec ZFS:0000033Hatching:Long-pec ZFS:0000030Pharyngula:Prim-15 ZFS:0000031Pharyngula:Prim-25	6.34e3 6.34e3 6.97e3 6.97e3 7.01e3 1.25e4 1.27e4 1.37e4 1.38e4	78.56468 78.56468 76.46045 76.46045 76.30396 57.67708 57.12595 53.55284 53.31307	AEIR AEIR AEIR AEIR AEIR AEIR AEIR AEIR AEIR
UBERON:0000948	heart	[+] 1 stage UBERON:0000066fully formed stage	6.86e3 6.86e3	76.80817 76.80817	AEIR AEIR
UBERON:0002199	integument	[+] 1 stage UBERON:0000066fully formed stage	7.36e3 7.36e3	75.11204 75.11204	AEIR AEIR
UBERON:0003064	intermediate mesoderm	[+] 1 stage ZFS:0000029Pharyngula:Prim-5	7.40e3 7.40e3	75.00167 75.00167	AEIR AEIR
UBERON:0002120	pronephros	[+] 5 stages ZFS:0000035Larval:Protruding-mouth ZFS:0000030Pharyngula:Prim-15 ZFS:0000033Hatching:Long-pec ZFS:0000029Pharyngula:Prim-5 ZFS:0000027Segmentation:20-25 somites	7.40e3 7.40e3 9.51e3 1.29e4 1.33e4 1.48e4	74.99998 74.99998 67.84530 56.24156 54.98815 49.99155	AEIR AEIR AEIR AEIR AEIR AEIR
UBERON:0005310	pronephric nephron tubule	[+] 1 stage ZFS:0000033Hatching:Long-pec	7.40e3 7.40e3	74.99829 74.99829	AEIR AEIR
ZFA:0000023	forerunner cell group (Danio)	[+] 6 stages ZFS:0000022Gastrula:Bud ZFS:0000019Gastrula:Shield ZFS:0000020Gastrula:75%-epiboly ZFS:0000021Gastrula:90%-epiboly ZFS:0000017Gastrula:50%-epiboly ZFS:0000018Gastrula:Germ-ring	7.40e3 7.40e3 9.11e3 1.02e4 1.02e4 1.08e4 1.08e4	74.99153 74.99153 69.22062 65.60979 65.37279 63.62621 63.62621	AEIR AEIR AEIR AEIR AEIR AEIR AEIR
UBERON:0001049	neural tube	[+] 5 stages ZFS:0000026Segmentation:14-19 somites ZFS:0000027Segmentation:20-25 somites ZFS:0000025Segmentation:10-13 somites ZFS:0000029Pharyngula:Prim-5 ZFS:0000028Segmentation:26+ somites	7.40e3 7.40e3 9.62e3 9.86e3 1.03e4 1.11e4	74.98646 74.98646 67.48142 66.66666 65.19372 62.47802	AEIR AEIR AEIR AEIR AEIR AEIR
UBERON:0002082	cardiac ventricle	[+] 1 stage UBERON:0000066fully formed stage	7.71e3 7.71e3	73.93254 73.93254	AEIR AEIR
UBERON:0002028	hindbrain	[+] 7 stages ZFS:0000031Pharyngula:Prim-25 ZFS:0000030Pharyngula:Prim-15 ZFS:0000028Segmentation:26+ somites ZFS:0000033Hatching:Long-pec ZFS:0000027Segmentation:20-25 somites ZFS:0000029Pharyngula:Prim-5 ZFS:0000032Pharyngula:High-pec	7.72e3 7.72e3 8.14e3 1.04e4 1.04e4 1.06e4 1.06e4 1.09e4	73.89614 73.89614 72.48478 64.97970 64.97970 64.26374 64.25529 63.13761	AEIR AEIR AEIR AEIR AEIR AEIR AEIR AEIR
UBERON:0002113	kidney	[+] 1 stage UBERON:0000066fully formed stage	8.00e3 8.00e3	72.97754 72.97754	AEIR AEIR
UBERON:0002548	larva	[+] 3 stages ZFS:0000037Larval:Day 5 UBERON:0000069larval stage ZFS:0000035Larval:Protruding-mouth	8.04e3 8.04e3 9.51e3 9.98e3	72.82260 72.82260 67.84523 66.27458	AEIR AEIR AEIR AEIR
UBERON:0003050	olfactory placode	[+] 3 stages ZFS:0000029Pharyngula:Prim-5 ZFS:0000027Segmentation:20-25 somites ZFS:0000028Segmentation:26+ somites	8.14e3 8.14e3 8.22e3 8.22e3	72.48478 72.48478 72.20871 72.20871	AEIR AEIR AEIR AEIR
UBERON:0000014	zone of skin	[+] 1 stage UBERON:0000066fully formed stage	8.33e3 8.33e3	71.86531 71.86531	AEIR AEIR
UBERON:0001943	midbrain tegmentum	[+] 2 stages ZFS:0000030Pharyngula:Prim-15 ZFS:0000031Pharyngula:Prim-25	8.33e3 8.33e3 8.71e3	71.86318 71.86318 70.57472	AEIR AEIR AEIR
UBERON:0001894	diencephalon	[+] 6 stages ZFS:0000027Segmentation:20-25 somites ZFS:0000030Pharyngula:Prim-15 ZFS:0000028Segmentation:26+ somites ZFS:0000029Pharyngula:Prim-5 ZFS:0000031Pharyngula:Prim-25 ZFS:0000026Segmentation:14-19 somites	8.37e3 8.37e3 8.37e3 8.57e3 8.64e3 8.75e3 1.15e4	71.72055 71.72055 71.72055 71.03743 70.81304 70.43594 61.09084	AEIR AEIR AEIR AEIR AEIR AEIR AEIR
UBERON:0000966	retina	[+] 3 stages ZFS:0000031Pharyngula:Prim-25 ZFS:0000033Hatching:Long-pec UBERON:0000066fully formed stage	8.43e3 8.43e3 1.24e4 1.64e4	71.52041 71.52041 57.95525 44.66422	AEIR AEIR AEIR AEIR
UBERON:0007132	head kidney	[+] 1 stage UBERON:0000066fully formed stage	8.47e3 8.47e3	71.38560 71.38560	AEIR AEIR
UBERON:0000955	brain	[+] 3 stages ZFS:0000031Pharyngula:Prim-25 UBERON:0000066fully formed stage UBERON:0000104life cycle	8.67e3 8.67e3 9.84e3 1.48e4	70.70548 70.70548 66.75441 49.94254	AEIR AEIR AEIR AEIR
UBERON:0001891	midbrain	[+] 3 stages ZFS:0000027Segmentation:20-25 somites ZFS:0000028Segmentation:26+ somites ZFS:0000029Pharyngula:Prim-5	9.05e3 9.05e3 9.25e3 1.04e4	69.42923 69.42923 68.73648 64.97970	AEIR AEIR AEIR AEIR
UBERON:0003079	floor plate	[+] 6 stages ZFS:0000029Pharyngula:Prim-5 ZFS:0000028Segmentation:26+ somites ZFS:0000027Segmentation:20-25 somites ZFS:0000023Segmentation:1-4 somites ZFS:0000024Segmentation:5-9 somites ZFS:0000025Segmentation:10-13 somites	9.25e3 9.25e3 9.87e3 1.02e4 1.15e4 1.15e4 1.18e4	68.73648 68.73648 66.65652 65.37279 61.10267 61.10267 59.98986	AEIR AEIR AEIR AEIR AEIR AEIR AEIR
UBERON:0000033	head	[+] 2 stages UBERON:0000066fully formed stage ZFS:0000037Larval:Day 5	9.31e3 9.31e3 1.07e4	68.52619 68.52619 63.73755	AEIR AEIR AEIR
UBERON:0010285	midbrain basal plate	[+] 1 stage ZFS:0000026Segmentation:14-19 somites	9.86e3 9.86e3	66.66666 66.66666	AEIR AEIR
ZFA:0000092	axis (Danio)	[+] 6 stages ZFS:0000019Gastrula:Shield ZFS:0000020Gastrula:75%-epiboly ZFS:0000022Gastrula:Bud ZFS:0000017Gastrula:50%-epiboly ZFS:0000018Gastrula:Germ-ring ZFS:0000021Gastrula:90%-epiboly	9.87e3 9.87e3 9.87e3 9.87e3 1.04e4 1.04e4 1.04e4	66.64976 66.64976 66.64976 66.64976 64.68900 64.68900 64.68900	AEIR AEIR AEIR AEIR AEIR AEIR AEIR
UBERON:0002481	bone tissue	[+] 1 stage UBERON:0000066fully formed stage	1.01e4 1.01e4	66.03181 66.03181	AEIR AEIR
UBERON:0000004	nose	[+] 3 stages ZFS:0000033Hatching:Long-pec ZFS:0000032Pharyngula:High-pec ZFS:0000035Larval:Protruding-mouth	1.02e4 1.02e4 1.04e4 1.48e4	65.60979 65.60979 64.68900 50.00000	AEIR AEIR AEIR AEIR
UBERON:0002385	muscle tissue	[+] 1 stage UBERON:0000066fully formed stage	1.04e4 1.04e4	64.84545 64.84545	AEIR AEIR
UBERON:0001898	hypothalamus	[+] 2 stages ZFS:0000033Hatching:Long-pec ZFS:0000032Pharyngula:High-pec	1.06e4 1.06e4 1.08e4	64.27218 64.27218 63.62621	AEIR AEIR AEIR
UBERON:0002240	spinal cord	[+] 3 stages ZFS:0000029Pharyngula:Prim-5 ZFS:0000027Segmentation:20-25 somites ZFS:0000028Segmentation:26+ somites	1.06e4 1.06e4 1.11e4 1.11e4	64.25529 64.25529 62.47802 62.47802	AEIR AEIR AEIR AEIR
UBERON:0003982	mature ovarian follicle	[+] 1 stage UBERON:0000066fully formed stage	1.07e4 1.07e4	63.82810 63.82810	AEIR AEIR
UBERON:0003309	floor plate of diencephalon	[+] 1 stage ZFS:0000026Segmentation:14-19 somites	1.11e4 1.11e4	62.49830 62.49830	AEIR AEIR
UBERON:2000887	floor plate neural rod	[+] 1 stage ZFS:0000026Segmentation:14-19 somites	1.11e4 1.11e4	62.49830 62.49830	AEIR AEIR
UBERON:0003081	lateral plate mesoderm	[+] 1 stage ZFS:0000026Segmentation:14-19 somites	1.11e4 1.11e4	62.49323 62.49323	AEIR AEIR
UBERON:0003052	midbrain-hindbrain boundary	[+] 1 stage ZFS:0000026Segmentation:14-19 somites	1.11e4 1.11e4	62.48309 62.48309	AEIR AEIR
UBERON:0004879	marginal zone of embryo	[+] 6 stages ZFS:0000021Gastrula:90%-epiboly ZFS:0000019Gastrula:Shield ZFS:0000020Gastrula:75%-epiboly ZFS:0000018Gastrula:Germ-ring ZFS:0000022Gastrula:Bud ZFS:0000017Gastrula:50%-epiboly	1.16e4 1.16e4 1.17e4 1.17e4 1.28e4 1.28e4 1.30e4	60.69907 60.69907 60.50435 60.50435 56.64807 56.64807 56.22973	AEIR AEIR AEIR AEIR AEIR AEIR AEIR
UBERON:0001893	telencephalon	[+] 3 stages ZFS:0000027Segmentation:20-25 somites ZFS:0000029Pharyngula:Prim-5 ZFS:0000028Segmentation:26+ somites	1.17e4 1.17e4 1.17e4 1.23e4	60.50435 60.50435 60.38795 58.31136	AEIR AEIR AEIR AEIR
UBERON:0002107	liver	[+] 1 stage UBERON:0000066fully formed stage	1.19e4 1.19e4	59.84189 59.84189	AEIR AEIR
UBERON:0000160	intestine	[+] 1 stage UBERON:0000066fully formed stage	1.23e4 1.23e4	58.35601 58.35601	AEIR AEIR
UBERON:2000001	Kupffer's vesicle	[+] 1 stage ZFS:0000023Segmentation:1-4 somites	1.23e4 1.23e4	58.31981 58.31981	AEIR AEIR
UBERON:0002106	spleen	[+] 1 stage UBERON:0000066fully formed stage	1.27e4 1.27e4	57.11558 57.11558	AEIR AEIR
UBERON:0000206	pharyngeal gill	[+] 1 stage UBERON:0000066fully formed stage	1.34e4 1.34e4	54.77667 54.77667	AEIR AEIR
UBERON:0007135	neural keel	[+] 1 stage ZFS:0000022Gastrula:Bud	1.35e4 1.35e4	54.53193 54.53193	AEIR AEIR
UBERON:0003075	neural plate	[+] 3 stages ZFS:0000024Segmentation:5-9 somites ZFS:0000025Segmentation:10-13 somites ZFS:0000023Segmentation:1-4 somites	1.40e4 1.40e4 1.40e4 1.41e4	52.60453 52.60453 52.60453 52.35053	AEIR AEIR AEIR AEIR
UBERON:0007286	presumptive floor plate	[+] 1 stage ZFS:0000021Gastrula:90%-epiboly	1.48e4 1.48e4	50.00169 50.00169	AEIR AEIR
UBERON:0003308	floor plate of telencephalon	[+] 1 stage ZFS:0000026Segmentation:14-19 somites	1.48e4 1.48e4	50.00000 50.00000	AEIR AEIR
UBERON:0005566	rhombomere 1 floor plate	[+] 1 stage ZFS:0000026Segmentation:14-19 somites	1.48e4 1.48e4	50.00000 50.00000	AEIR AEIR
UBERON:0005570	rhombomere 2 floor plate	[+] 1 stage ZFS:0000026Segmentation:14-19 somites	1.48e4 1.48e4	50.00000 50.00000	AEIR AEIR
UBERON:0005573	rhombomere 3 floor plate	[+] 1 stage ZFS:0000026Segmentation:14-19 somites	1.48e4 1.48e4	50.00000 50.00000	AEIR AEIR
UBERON:0005576	rhombomere 4 floor plate	[+] 1 stage ZFS:0000026Segmentation:14-19 somites	1.48e4 1.48e4	50.00000 50.00000	AEIR AEIR
UBERON:0005579	rhombomere 5 floor plate	[+] 1 stage ZFS:0000026Segmentation:14-19 somites	1.48e4 1.48e4	50.00000 50.00000	AEIR AEIR
UBERON:0005582	rhombomere 6 floor plate	[+] 1 stage ZFS:0000026Segmentation:14-19 somites	1.48e4 1.48e4	50.00000 50.00000	AEIR AEIR
UBERON:0005585	rhombomere 7 floor plate	[+] 1 stage ZFS:0000026Segmentation:14-19 somites	1.48e4 1.48e4	50.00000 50.00000	AEIR AEIR
UBERON:0005588	rhombomere 8 floor plate	[+] 1 stage ZFS:0000026Segmentation:14-19 somites	1.48e4 1.48e4	50.00000 50.00000	AEIR AEIR
UBERON:0007308	pronephric distal early tubule	[+] 1 stage ZFS:0000033Hatching:Long-pec	1.48e4 1.48e4	49.99662 49.99662	AEIR AEIR
UBERON:0009622	pronephric proximal straight tubule	[+] 1 stage ZFS:0000033Hatching:Long-pec	1.48e4 1.48e4	49.99662 49.99662	AEIR AEIR

Sources
A	Affymetrix
E	EST
I	In Situ
R	RNA-Seq

data

no data

Rank scores
3.25e4	lightgrey: low confidence scores
	important score variation

Rank scores of expression calls are normalized across genes, conditions and species. Low score means that the gene is highly expressed in the condition. Max rank score in all species: 4.10e4. Min rank score varies across species.

Expression scores of expression calls use the minimum and maximum Rank of the species to normalize the expression to a value between 0 and 100. Low score means that the gene is lowly expressed in the condition.

Sources of annotations to anatomy and development:

Affymetrix data: Bgee
EST data: Bgee
In situ hybridization data: ZFIN
RNA-Seq data: Bgee

Sources of raw data:

Affymetrix data: ArrayExpress, GEO
EST data: UniGene
In situ hybridization data: ZFIN
RNA-Seq data: GEO

Cross-references

EMBL	BC090314, BX664738, CR450804
Ensembl	ENSDARG00000013575 (rfx2)
Uniprot/SPTREMBL	E9QCU4, E9QCU4_DANRE, E9QEW4, E9QEW4_DANRE, E9QJ42, E9QJ42_DANRE
Uniprot/SWISSPROT	Q5EAP5, RFX2_DANRE
ZFIN	ZDB-GENE-050227-4 (rfx2)