D. rerio Gene: pak2b - ENSDARG00000018476 - Danio rerio (zebrafish)

General information

Ensembl IDENSDARG00000018476
Namepak2b
Descriptionp21 protein (Cdc42/Rac)-activated kinase 2b [Source:ZFIN;Acc:ZDB-GENE-030131-3759]
OrganismDanio rerio (zebrafish)
Synonym(s)ch73-159l23.1, wu:fc52b03, zgc:113857
Orthologs(s)26 orthologs
Paralog(s)439 paralogs

Expression

Anat. entity IDAnatomical entityDevelopmental stage(s)Rank scoreExpression scoreSources
UBERON:0004734gastrula
  • ZFS:0000019Gastrula:Shield
  • ZFS:0000022Gastrula:Bud
  • UBERON:0000109gastrula stage
  • ZFS:0000020Gastrula:75%-epiboly
  • ZFS:0000021Gastrula:90%-epiboly
  • ZFS:0000017Gastrula:50%-epiboly
890
  • 890
  • 919
  • 964
  • 1.09e3
  • 1.12e3
  • 1.37e3
97.02
  • 97.02
  • 96.93
  • 96.77
  • 96.37
  • 96.26
  • 95.43
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0000468multi-cellular organism
  • ZFS:0000021Gastrula:90%-epiboly
  • ZFS:0000026Segmentation:14-19 somites
  • ZFS:0000019Gastrula:Shield
  • ZFS:0000020Gastrula:75%-epiboly
  • ZFS:0000022Gastrula:Bud
  • ZFS:0000024Segmentation:5-9 somites
  • ZFS:0000030Pharyngula:Prim-15
  • ZFS:0000033Hatching:Long-pec
  • ZFS:0000029Pharyngula:Prim-5
  • ZFS:0000037Larval:Day 5
  • ZFS:0000040Larval:Days 14-20
  • ZFS:0000036Larval:Day 4
  • ZFS:0000042Juvenile:Days 30-44
  • UBERON:0000106zygote stage
  • ZFS:0000049segmentation
  • UBERON:0000068embryo stage
  • UBERON:0000104life cycle
  • UBERON:0000066fully formed stage
985
  • 985
  • 1.02e3
  • 1.05e3
  • 1.06e3
  • 1.12e3
  • 1.43e3
  • 1.87e3
  • 1.97e3
  • 2.10e3
  • 2.36e3
  • 2.63e3
  • 3.02e3
  • 4.01e3
  • 4.52e3
  • 1.31e4
  • 1.44e4
  • 1.47e4
  • 1.50e4
96.70
  • 96.70
  • 96.57
  • 96.49
  • 96.45
  • 96.27
  • 95.23
  • 93.73
  • 93.41
  • 92.96
  • 92.10
  • 91.19
  • 89.91
  • 86.59
  • 84.88
  • 56.21
  • 51.82
  • 50.90
  • 49.81
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0003059presomitic mesoderm
  • ZFS:0000025Segmentation:10-13 somites
1.17e3
  • 1.17e3
96.07
  • 96.07
AEIR
  • AEIR
UBERON:0000922embryo
  • ZFS:0000024Segmentation:5-9 somites
  • UBERON:0004707pharyngula stage
  • ZFS:0000029Pharyngula:Prim-5
  • ZFS:0000033Hatching:Long-pec
  • UBERON:0000068embryo stage
  • ZFS:0000025Segmentation:10-13 somites
  • ZFS:0000031Pharyngula:Prim-25
  • ZFS:0000030Pharyngula:Prim-15
  • ZFS:0000026Segmentation:14-19 somites
  • ZFS:0000037Larval:Day 5
1.32e3
  • 1.32e3
  • 1.46e3
  • 1.56e3
  • 1.68e3
  • 1.77e3
  • 2.11e3
  • 2.30e3
  • 2.42e3
  • 2.78e3
  • 3.02e3
95.59
  • 95.59
  • 95.12
  • 94.77
  • 94.37
  • 94.09
  • 92.95
  • 92.32
  • 91.91
  • 90.70
  • 89.91
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0000307blastula
  • ZFS:0000015Blastula:Dome
  • ZFS:0000016Blastula:30%-epiboly
  • ZFS:0000011Blastula:1k-cell
  • ZFS:0000009Blastula:256-cell
  • ZFS:0000014Blastula:Sphere
1.37e3
  • 1.37e3
  • 1.67e3
  • 2.55e3
  • 6.62e3
  • 6.85e3
95.42
  • 95.42
  • 94.42
  • 91.45
  • 77.82
  • 77.07
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0009620tail bud paraxial mesoderm
  • ZFS:0000027Segmentation:20-25 somites
1.48e3
  • 1.48e3
95.06
  • 95.06
AEIR
  • AEIR
UBERON:0000970eye
  • ZFS:0000031Pharyngula:Prim-25
1.48e3
  • 1.48e3
95.04
  • 95.04
AEIR
  • AEIR
UBERON:0000966retina
  • ZFS:0000033Hatching:Long-pec
  • ZFS:0000031Pharyngula:Prim-25
  • ZFS:0000037Larval:Day 5
  • UBERON:0000066fully formed stage
1.52e3
  • 1.52e3
  • 1.57e3
  • 3.43e3
  • 4.92e3
94.92
  • 94.92
  • 94.75
  • 88.52
  • 83.54
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0002329somite
  • ZFS:0000025Segmentation:10-13 somites
1.85e3
  • 1.85e3
93.80
  • 93.80
AEIR
  • AEIR
UBERON:0000033head
  • ZFS:0000037Larval:Day 5
  • UBERON:0000066fully formed stage
2.19e3
  • 2.19e3
  • 7.61e3
92.66
  • 92.66
  • 74.52
AEIR
  • AEIR
  • AEIR
UBERON:0001630muscle organ
  • UBERON:0000066fully formed stage
2.21e3
  • 2.21e3
92.59
  • 92.59
AEIR
  • AEIR
UBERON:0000948heart
  • ZFS:0000036Larval:Day 4
  • UBERON:0000066fully formed stage
2.23e3
  • 2.23e3
  • 5.18e3
92.54
  • 92.54
  • 82.66
AEIR
  • AEIR
  • AEIR
UBERON:4000164caudal fin
  • ZFS:0000033Hatching:Long-pec
  • UBERON:0000066fully formed stage
2.32e3
  • 2.32e3
  • 6.04e3
92.24
  • 92.24
  • 79.79
AEIR
  • AEIR
  • AEIR
CL:0000094granulocyte
  • UBERON:0000066fully formed stage
2.61e3
  • 2.61e3
91.28
  • 91.28
AEIR
  • AEIR
UBERON:0002385muscle tissue
  • UBERON:0000066fully formed stage
2.78e3
  • 2.78e3
90.69
  • 90.69
AEIR
  • AEIR
UBERON:0019248early embryo
  • UBERON:0000107cleavage stage
2.82e3
  • 2.82e3
90.56
  • 90.56
AEIR
  • AEIR
UBERON:0002548larva
  • ZFS:0000037Larval:Day 5
  • UBERON:0000069larval stage
  • ZFS:0000035Larval:Protruding-mouth
3.18e3
  • 3.18e3
  • 3.29e3
  • 3.62e3
89.35
  • 89.35
  • 88.98
  • 87.89
AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0000955brain
  • UBERON:0000066fully formed stage
  • ZFS:0000031Pharyngula:Prim-25
  • ZFS:0000033Hatching:Long-pec
  • ZFS:0000032Pharyngula:High-pec
3.37e3
  • 3.37e3
  • 4.09e3
  • 1.22e4
  • 1.31e4
88.72
  • 88.72
  • 86.30
  • 59.08
  • 56.24
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0000992female gonad
  • UBERON:0000066fully formed stage
3.38e3
  • 3.38e3
88.69
  • 88.69
AEIR
  • AEIR
UBERON:0002481bone tissue
  • UBERON:0000066fully formed stage
3.48e3
  • 3.48e3
88.35
  • 88.35
AEIR
  • AEIR
UBERON:0007010cleaving embryo
  • ZFS:0000005Cleavage:16-cell
3.71e3
  • 3.71e3
87.58
  • 87.58
AEIR
  • AEIR
UBERON:0002113kidney
  • UBERON:0000066fully formed stage
3.87e3
  • 3.87e3
87.05
  • 87.05
AEIR
  • AEIR
UBERON:0000206pharyngeal gill
  • UBERON:0000066fully formed stage
3.92e3
  • 3.92e3
86.87
  • 86.87
AEIR
  • AEIR
UBERON:0002106spleen
  • UBERON:0000066fully formed stage
3.95e3
  • 3.95e3
86.76
  • 86.76
AEIR
  • AEIR
UBERON:0000014zone of skin
  • UBERON:0000066fully formed stage
4.31e3
  • 4.31e3
85.58
  • 85.58
AEIR
  • AEIR
UBERON:0003982mature ovarian follicle
  • UBERON:0000066fully formed stage
4.33e3
  • 4.33e3
85.50
  • 85.50
AEIR
  • AEIR
UBERON:0002082cardiac ventricle
  • UBERON:0000066fully formed stage
4.35e3
  • 4.35e3
85.43
  • 85.43
AEIR
  • AEIR
UBERON:0000473testis
  • UBERON:0000066fully formed stage
4.53e3
  • 4.53e3
84.82
  • 84.82
AEIR
  • AEIR
UBERON:0002415tail
  • UBERON:0000066fully formed stage
4.85e3
  • 4.85e3
83.78
  • 83.78
AEIR
  • AEIR
UBERON:0000160intestine
  • UBERON:0000066fully formed stage
4.88e3
  • 4.88e3
83.67
  • 83.67
AEIR
  • AEIR
UBERON:0000465material anatomical entity
  • UBERON:00072322 cell stage
  • UBERON:00072334 cell stage
  • UBERON:00072368 cell stage
  • ZFS:0000016Blastula:30%-epiboly
  • ZFS:0000018Gastrula:Germ-ring
  • UBERON:0000106zygote stage
  • UBERON:0004707pharyngula stage
  • ZFS:0000005Cleavage:16-cell
  • ZFS:0000006Cleavage:32-cell
  • ZFS:0000007Cleavage:64-cell
  • ZFS:0000008Blastula:128-cell
  • ZFS:0000009Blastula:256-cell
  • ZFS:0000010Blastula:512-cell
  • ZFS:0000011Blastula:1k-cell
  • ZFS:0000012Blastula:High
  • ZFS:0000013Blastula:Oblong
  • ZFS:0000015Blastula:Dome
  • ZFS:0000027Segmentation:20-25 somites
  • ZFS:0000034Hatching:Pec-fin
  • ZFS:0000022Gastrula:Bud
  • ZFS:0000028Segmentation:26+ somites
  • ZFS:0000017Gastrula:50%-epiboly
  • ZFS:0000023Segmentation:1-4 somites
  • ZFS:0000033Hatching:Long-pec
  • ZFS:0000019Gastrula:Shield
  • ZFS:0000020Gastrula:75%-epiboly
  • ZFS:0000021Gastrula:90%-epiboly
  • ZFS:0000025Segmentation:10-13 somites
  • ZFS:0000024Segmentation:5-9 somites
  • ZFS:0000014Blastula:Sphere
  • ZFS:0000026Segmentation:14-19 somites
6.40e3
  • 6.40e3
  • 6.40e3
  • 6.40e3
  • 6.64e3
  • 6.89e3
  • 7.47e3
  • 7.47e3
  • 7.47e3
  • 7.47e3
  • 7.47e3
  • 7.47e3
  • 7.47e3
  • 7.47e3
  • 7.47e3
  • 7.47e3
  • 7.47e3
  • 7.47e3
  • 7.97e3
  • 8.53e3
  • 8.54e3
  • 8.71e3
  • 8.79e3
  • 8.79e3
  • 8.96e3
  • 8.96e3
  • 9.13e3
  • 9.13e3
  • 9.13e3
  • 9.71e3
  • 9.96e3
  • 9.96e3
78.57
  • 78.57
  • 78.57
  • 78.57
  • 77.77
  • 76.92
  • 75.00
  • 75.00
  • 75.00
  • 75.00
  • 75.00
  • 75.00
  • 75.00
  • 75.00
  • 75.00
  • 75.00
  • 75.00
  • 75.00
  • 73.32
  • 71.43
  • 71.41
  • 70.82
  • 70.57
  • 70.57
  • 69.99
  • 69.98
  • 69.43
  • 69.43
  • 69.43
  • 67.48
  • 66.66
  • 66.65
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0002107liver
  • UBERON:0000066fully formed stage
7.97e3
  • 7.97e3
73.32
  • 73.32
AEIR
  • AEIR
UBERON:0007132head kidney
  • UBERON:0000066fully formed stage
9.27e3
  • 9.27e3
68.95
  • 68.95
AEIR
  • AEIR
UBERON:0005805dorsal aorta
  • ZFS:0000033Hatching:Long-pec
9.96e3
  • 9.96e3
66.66
  • 66.66
AEIR
  • AEIR
UBERON:0006860swim bladder
  • UBERON:0000066fully formed stage
1.00e4
  • 1.00e4
66.43
  • 66.43
AEIR
  • AEIR
UBERON:2001073axial vasculature
  • ZFS:0000032Pharyngula:High-pec
1.24e4
  • 1.24e4
58.33
  • 58.33
AEIR
  • AEIR
UBERON:0001017central nervous system
  • ZFS:0000032Pharyngula:High-pec
1.26e4
  • 1.26e4
57.68
  • 57.68
AEIR
  • AEIR
UBERON:0000925endoderm
  • ZFS:0000033Hatching:Long-pec
1.28e4
  • 1.28e4
57.14
  • 57.14
AEIR
  • AEIR
UBERON:0002240spinal cord
  • ZFS:0000033Hatching:Long-pec
  • ZFS:0000031Pharyngula:Prim-25
  • ZFS:0000032Pharyngula:High-pec
1.34e4
  • 1.34e4
  • 1.36e4
  • 1.41e4
55.24
  • 55.24
  • 54.52
  • 52.92
AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0001792ganglionic layer of retina
  • ZFS:0000032Pharyngula:High-pec
1.37e4
  • 1.37e4
54.15
  • 54.15
AEIR
  • AEIR
UBERON:0003053ventricular zone
  • ZFS:0000032Pharyngula:High-pec
1.37e4
  • 1.37e4
54.15
  • 54.15
AEIR
  • AEIR
CL:0000740retinal ganglion cell
  • ZFS:0000032Pharyngula:High-pec
1.49e4
  • 1.49e4
50.00
  • 50.00
AEIR
  • AEIR
UBERON:0002291central canal of spinal cord
  • ZFS:0000032Pharyngula:High-pec
1.49e4
  • 1.49e4
50.00
  • 50.00
AEIR
  • AEIR
Sources
AAffymetrix
EEST
IIn Situ
RRNA-Seq
data
no data
Rank scores
3.25e4lightgrey: low confidence scores

important score variation

Rank scores of expression calls are normalized across genes, conditions and species. Low score means that the gene is highly expressed in the condition. Max rank score in all species: 4.10e4. Min rank score varies across species.

Expression scores of expression calls use the minimum and maximum Rank of the species to normalize the expression to a value between 0 and 100. Low score means that the gene is lowly expressed in the condition.

Sources of annotations to anatomy and development:
  • Affymetrix data: Bgee
  • EST data: Bgee
  • In situ hybridization data: ZFIN
  • RNA-Seq data: Bgee
Sources of raw data:

Orthologs

Taxon nameSpecies with orthologsGene(s)Expression comparisonSee details
Euteleostomi19 species19 genesCompare expression
Bilateria26 species26 genesCompare expression

Orthology information comes from OMA : ENSDARG00000018476.

Paralogs (same species)

Taxon nameGene(s)Expression comparisonSee details
Clupeocephala1 geneCompare expression
Eukaryota439 genesCompare expression

Paralogy information comes from OMA : ENSDARG00000018476.

Cross-references

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