Gene: bdnf - ENSDARG00000018817 - Danio rerio (zebrafish)

General information

Ensembl ID	ENSDARG00000018817
Name	bdnf
Description	brain-derived neurotrophic factor [Source:ZFIN;Acc:ZDB-GENE-000412-1]
Organism	Danio rerio (zebrafish)
Orthologs(s)	18 orthologs

Expression

Anat. entity ID	Anatomical entity	Developmental stage(s)	Rank score	Expression score	Sources
UBERON:0000019	camera-type eye	[+] 1 stage ZFS:0000035Larval:Protruding-mouth	1.38e3 1.38e3	95.40 95.40	AEIR AEIR
UBERON:0000955	brain	[+] 6 stages UBERON:0000066fully formed stage ZFS:0000033Hatching:Long-pec ZFS:0000037Larval:Day 5 ZFS:0000036Larval:Day 4 ZFS:0000031Pharyngula:Prim-25 UBERON:0000104life cycle	2.28e3 2.28e3 6.79e3 8.96e3 9.96e3 1.31e4 1.41e4	92.36 92.36 77.27 69.99 66.67 56.21 52.72	AEIR AEIR AEIR AEIR AEIR AEIR AEIR
UBERON:0000033	head	[+] 2 stages ZFS:0000037Larval:Day 5 UBERON:0000066fully formed stage	2.65e3 2.65e3 1.09e4	91.14 91.14 63.59	AEIR AEIR AEIR
UBERON:0000151	pectoral fin	[+] 1 stage ZFS:0000036Larval:Day 4	4.98e3 4.98e3	83.34 83.34	AEIR AEIR
UBERON:0008904	neuromast	[+] 4 stages ZFS:0000036Larval:Day 4 ZFS:0000033Hatching:Long-pec ZFS:0000032Pharyngula:High-pec ZFS:0000035Larval:Protruding-mouth	4.98e3 4.98e3 7.47e3 1.12e4 1.28e4	83.34 83.34 74.99 62.49 57.14	AEIR AEIR AEIR AEIR AEIR
UBERON:0001893	telencephalon	[+] 7 stages ZFS:0000031Pharyngula:Prim-25 ZFS:0000033Hatching:Long-pec ZFS:0000027Segmentation:20-25 somites ZFS:0000029Pharyngula:Prim-5 ZFS:0000032Pharyngula:High-pec ZFS:0000028Segmentation:26+ somites ZFS:0000030Pharyngula:Prim-15	6.29e3 6.29e3 7.47e3 1.18e4 1.18e4 1.21e4 1.25e4 1.26e4	78.94 78.94 74.99 60.50 60.39 59.36 58.31 57.87	AEIR AEIR AEIR AEIR AEIR AEIR AEIR AEIR
UBERON:0001846	internal ear	[+] 2 stages ZFS:0000033Hatching:Long-pec ZFS:0000037Larval:Day 5	6.64e3 6.64e3 7.47e3	77.77 77.77 75.00	AEIR AEIR AEIR
UBERON:0000966	retina	[+] 3 stages ZFS:0000037Larval:Day 5 ZFS:0000032Pharyngula:High-pec ZFS:0000033Hatching:Long-pec	7.30e3 7.30e3 1.20e4 1.74e4	75.55 75.55 59.98 41.64	AEIR AEIR AEIR AEIR
UBERON:0000203	pallium	[+] 6 stages ZFS:0000037Larval:Day 5 ZFS:0000039Larval:Days 7-13 ZFS:0000033Hatching:Long-pec ZFS:0000035Larval:Protruding-mouth ZFS:0000029Pharyngula:Prim-5 ZFS:0000036Larval:Day 4	7.47e3 7.47e3 7.47e3 9.96e3 9.96e3 1.19e4 1.49e4	75.00 75.00 75.00 66.67 66.67 60.00 50.00	AEIR AEIR AEIR AEIR AEIR AEIR AEIR
UBERON:0001997	olfactory epithelium	[+] 2 stages ZFS:0000036Larval:Day 4 UBERON:0000104life cycle	7.47e3 7.47e3 1.38e4	75.00 75.00 53.81	AEIR AEIR AEIR
UBERON:2000711	DEL	[+] 1 stage ZFS:0000017Gastrula:50%-epiboly	7.47e3 7.47e3	75.00 75.00	AEIR AEIR
UBERON:4000164	caudal fin	[+] 1 stage ZFS:0000036Larval:Day 4	7.47e3 7.47e3	75.00 75.00	AEIR AEIR
UBERON:0001892	rhombomere	[+] 2 stages ZFS:0000033Hatching:Long-pec ZFS:0000031Pharyngula:Prim-25	7.47e3 7.47e3 9.96e3	75.00 75.00 66.66	AEIR AEIR AEIR
UBERON:0001891	midbrain	[+] 4 stages ZFS:0000031Pharyngula:Prim-25 ZFS:0000033Hatching:Long-pec ZFS:0000037Larval:Day 5 ZFS:0000029Pharyngula:Prim-5	7.91e3 7.91e3 8.96e3 1.12e4 1.34e4	73.52 73.52 69.99 62.49 54.97	AEIR AEIR AEIR AEIR AEIR
UBERON:0001890	forebrain	[+] 3 stages ZFS:0000031Pharyngula:Prim-25 ZFS:0000033Hatching:Long-pec ZFS:0000029Pharyngula:Prim-5	8.04e3 8.04e3 8.96e3 9.13e3	73.07 73.07 69.99 69.43	AEIR AEIR AEIR AEIR
UBERON:0002028	hindbrain	[+] 5 stages ZFS:0000033Hatching:Long-pec ZFS:0000029Pharyngula:Prim-5 ZFS:0000031Pharyngula:Prim-25 ZFS:0000037Larval:Day 5 ZFS:0000039Larval:Days 7-13	8.22e3 8.22e3 9.07e3 9.10e3 1.34e4 1.49e4	72.48 72.48 69.62 69.55 54.99 50.00	AEIR AEIR AEIR AEIR AEIR AEIR
UBERON:0000922	embryo	[+] 9 stages ZFS:0000037Larval:Day 5 ZFS:0000033Hatching:Long-pec ZFS:0000024Segmentation:5-9 somites ZFS:0000030Pharyngula:Prim-15 ZFS:0000029Pharyngula:Prim-5 UBERON:0004707pharyngula stage ZFS:0000031Pharyngula:Prim-25 ZFS:0000025Segmentation:10-13 somites UBERON:0000068embryo stage	8.40e3 8.40e3 1.32e4 1.52e4 1.54e4 1.64e4 1.67e4 1.78e4 1.78e4 1.84e4	71.88 71.88 55.92 49.13 48.54 45.05 44.00 40.54 40.40 38.28	AEIR AEIR AEIR AEIR AEIR AEIR AEIR AEIR AEIR AEIR
UBERON:0001792	ganglionic layer of retina	[+] 3 stages ZFS:0000033Hatching:Long-pec ZFS:0000036Larval:Day 4 ZFS:0000032Pharyngula:High-pec	8.96e3 8.96e3 9.96e3 1.12e4	69.99 69.99 66.67 62.49	AEIR AEIR AEIR AEIR
UBERON:0003051	ear vesicle	[+] 4 stages ZFS:0000033Hatching:Long-pec ZFS:0000029Pharyngula:Prim-5 ZFS:0000035Larval:Protruding-mouth ZFS:0000036Larval:Day 4	8.96e3 8.96e3 1.25e4 1.28e4 1.49e4	69.98 69.98 58.29 57.14 50.00	AEIR AEIR AEIR AEIR AEIR
UBERON:0001894	diencephalon	[+] 2 stages ZFS:0000031Pharyngula:Prim-25 ZFS:0000033Hatching:Long-pec	9.51e3 9.51e3 9.96e3	68.16 68.16 66.65	AEIR AEIR AEIR
UBERON:0002240	spinal cord	[+] 5 stages ZFS:0000029Pharyngula:Prim-5 ZFS:0000030Pharyngula:Prim-15 ZFS:0000031Pharyngula:Prim-25 ZFS:0000027Segmentation:20-25 somites ZFS:0000028Segmentation:26+ somites	9.61e3 9.61e3 1.15e4 1.22e4 1.27e4 1.27e4	67.83 67.83 61.34 59.06 57.47 57.47	AEIR AEIR AEIR AEIR AEIR AEIR
UBERON:0001943	midbrain tegmentum	[+] 2 stages ZFS:0000031Pharyngula:Prim-25 ZFS:0000033Hatching:Long-pec	9.67e3 9.67e3 1.03e4	67.63 67.63 65.61	AEIR AEIR AEIR
UBERON:0002548	larva	[+] 3 stages ZFS:0000035Larval:Protruding-mouth ZFS:0000037Larval:Day 5 UBERON:0000069larval stage	9.84e3 9.84e3 9.98e3 1.06e4	67.04 67.04 66.60 64.41	AEIR AEIR AEIR AEIR
UBERON:0000468	multi-cellular organism	[+] 14 stages ZFS:0000037Larval:Day 5 ZFS:0000017Gastrula:50%-epiboly ZFS:0000036Larval:Day 4 UBERON:0000104life cycle ZFS:0000027Segmentation:20-25 somites ZFS:0000040Larval:Days 14-20 UBERON:0000068embryo stage ZFS:0000033Hatching:Long-pec ZFS:0000026Segmentation:14-19 somites ZFS:0000022Gastrula:Bud ZFS:0000029Pharyngula:Prim-5 ZFS:0000019Gastrula:Shield ZFS:0000030Pharyngula:Prim-15 ZFS:0000024Segmentation:5-9 somites	9.95e3 9.95e3 1.14e4 1.27e4 1.29e4 1.29e4 1.30e4 1.38e4 1.40e4 1.56e4 1.56e4 1.57e4 1.58e4 1.58e4 1.68e4	66.68 66.68 61.75 57.53 56.79 56.65 56.38 53.84 53.21 47.91 47.74 47.39 47.16 47.13 43.69	AEIR AEIR AEIR AEIR AEIR AEIR AEIR AEIR AEIR AEIR AEIR AEIR AEIR AEIR AEIR
UBERON:0001898	hypothalamus	[+] 4 stages ZFS:0000036Larval:Day 4 ZFS:0000029Pharyngula:Prim-5 ZFS:0000035Larval:Protruding-mouth ZFS:0000033Hatching:Long-pec	9.96e3 9.96e3 1.22e4 1.31e4 1.39e4	66.67 66.67 59.08 56.24 53.55	AEIR AEIR AEIR AEIR AEIR
UBERON:2000633	caudal tuberculum	[+] 4 stages ZFS:0000036Larval:Day 4 ZFS:0000029Pharyngula:Prim-5 ZFS:0000033Hatching:Long-pec ZFS:0000035Larval:Protruding-mouth	9.96e3 9.96e3 1.19e4 1.33e4 1.49e4	66.67 66.67 60.00 55.55 49.99	AEIR AEIR AEIR AEIR AEIR
UBERON:0001945	superior colliculus	[+] 4 stages ZFS:0000036Larval:Day 4 ZFS:0000035Larval:Protruding-mouth ZFS:0000039Larval:Days 7-13 ZFS:0000037Larval:Day 5	1.12e4 1.12e4 1.37e4 1.49e4 1.49e4	62.50 62.50 54.15 50.00 49.99	AEIR AEIR AEIR AEIR AEIR
UBERON:0002264	olfactory bulb	[+] 2 stages ZFS:0000035Larval:Protruding-mouth ZFS:0000033Hatching:Long-pec	1.12e4 1.12e4 1.49e4	62.50 62.50 49.99	AEIR AEIR AEIR
ZFA:0000093	blastomere (Danio)	[+] 3 stages UBERON:00072334 cell stage UBERON:00072368 cell stage UBERON:00072322 cell stage	1.12e4 1.12e4 1.12e4 1.49e4	62.50 62.50 62.50 50.00	AEIR AEIR AEIR AEIR
UBERON:0001714	cranial ganglion	[+] 7 stages ZFS:0000032Pharyngula:High-pec ZFS:0000029Pharyngula:Prim-5 ZFS:0000030Pharyngula:Prim-15 ZFS:0000031Pharyngula:Prim-25 ZFS:0000033Hatching:Long-pec ZFS:0000027Segmentation:20-25 somites ZFS:0000028Segmentation:26+ somites	1.12e4 1.12e4 1.12e4 1.17e4 1.17e4 1.17e4 1.20e4 1.20e4	62.49 62.49 62.48 60.70 60.70 60.70 59.98 59.98	AEIR AEIR AEIR AEIR AEIR AEIR AEIR AEIR
UBERON:0002540	lateral line system	[+] 4 stages ZFS:0000032Pharyngula:High-pec ZFS:0000033Hatching:Long-pec ZFS:0000030Pharyngula:Prim-15 ZFS:0000031Pharyngula:Prim-25	1.12e4 1.12e4 1.12e4 1.17e4 1.17e4	62.49 62.49 62.49 60.70 60.70	AEIR AEIR AEIR AEIR AEIR
UBERON:0000004	nose	[+] 4 stages ZFS:0000030Pharyngula:Prim-15 ZFS:0000031Pharyngula:Prim-25 ZFS:0000033Hatching:Long-pec ZFS:0000032Pharyngula:High-pec	1.14e4 1.14e4 1.14e4 1.21e4 1.23e4	61.75 61.75 61.75 59.36 58.80	AEIR AEIR AEIR AEIR AEIR
UBERON:0001049	neural tube	[+] 3 stages ZFS:0000029Pharyngula:Prim-5 ZFS:0000027Segmentation:20-25 somites ZFS:0000028Segmentation:26+ somites	1.17e4 1.17e4 1.27e4 1.27e4	60.84 60.84 57.47 57.47	AEIR AEIR AEIR AEIR
UBERON:0001928	preoptic area	[+] 1 stage ZFS:0000033Hatching:Long-pec	1.19e4 1.19e4	59.99 59.99	AEIR AEIR
UBERON:0004141	heart tube	[+] 1 stage ZFS:0000029Pharyngula:Prim-5	1.19e4 1.19e4	59.99 59.99	AEIR AEIR
UBERON:0003050	olfactory placode	[+] 3 stages ZFS:0000029Pharyngula:Prim-5 ZFS:0000027Segmentation:20-25 somites ZFS:0000028Segmentation:26+ somites	1.20e4 1.20e4 1.25e4 1.25e4	59.98 59.98 58.31 58.31	AEIR AEIR AEIR AEIR
CL:0000540	neuron	[+] 5 stages ZFS:0000030Pharyngula:Prim-15 ZFS:0000031Pharyngula:Prim-25 ZFS:0000027Segmentation:20-25 somites ZFS:0000028Segmentation:26+ somites ZFS:0000029Pharyngula:Prim-5	1.21e4 1.21e4 1.21e4 1.27e4 1.27e4 1.29e4	59.36 59.36 59.36 57.47 57.47 56.79	AEIR AEIR AEIR AEIR AEIR AEIR
UBERON:0000970	eye	[+] 1 stage ZFS:0000031Pharyngula:Prim-25	1.22e4 1.22e4	59.24 59.24	AEIR AEIR
UBERON:0001900	ventral thalamus	[+] 1 stage ZFS:0000029Pharyngula:Prim-5	1.28e4 1.28e4	57.14 57.14	AEIR AEIR
UBERON:0004128	optic vesicle	[+] 1 stage ZFS:0000024Segmentation:5-9 somites	1.28e4 1.28e4	57.13 57.13	AEIR AEIR
UBERON:0004734	gastrula	[+] 3 stages UBERON:0000109gastrula stage ZFS:0000019Gastrula:Shield ZFS:0000022Gastrula:Bud	1.29e4 1.29e4 1.40e4 1.51e4	56.75 56.75 53.10 49.37	AEIR AEIR AEIR AEIR
UBERON:0003072	optic cup	[+] 1 stage ZFS:0000029Pharyngula:Prim-5	1.34e4 1.34e4	54.99 54.99	AEIR AEIR
UBERON:0002329	somite	[+] 1 stage ZFS:0000029Pharyngula:Prim-5	1.37e4 1.37e4	54.13 54.13	AEIR AEIR
UBERON:0009614	hindbrain neural plate	[+] 3 stages ZFS:0000024Segmentation:5-9 somites ZFS:0000025Segmentation:10-13 somites ZFS:0000023Segmentation:1-4 somites	1.38e4 1.38e4 1.38e4 1.39e4	53.83 53.83 53.83 53.55	AEIR AEIR AEIR AEIR
UBERON:0000307	blastula	[+] 3 stages ZFS:0000016Blastula:30%-epiboly ZFS:0000011Blastula:1k-cell ZFS:0000015Blastula:Dome	1.40e4 1.40e4 1.51e4 1.58e4	53.25 53.25 49.50 47.19	AEIR AEIR AEIR AEIR
UBERON:0002037	cerebellum	[+] 1 stage ZFS:0000029Pharyngula:Prim-5	1.41e4 1.41e4	52.75 52.75	AEIR AEIR
UBERON:0000948	heart	[+] 2 stages ZFS:0000036Larval:Day 4 UBERON:0000066fully formed stage	1.45e4 1.45e4 1.92e4	51.36 51.36 35.80	AEIR AEIR AEIR
CL:0000856	neuromast hair cell	[+] 1 stage ZFS:0000036Larval:Day 4	1.49e4 1.49e4	50.00 50.00	AEIR AEIR
UBERON:0000162	cloaca	[+] 1 stage ZFS:0000036Larval:Day 4	1.49e4 1.49e4	50.00 50.00	AEIR AEIR
UBERON:0001707	nasal cavity	[+] 2 stages ZFS:0000037Larval:Day 5 ZFS:0000039Larval:Days 7-13	1.49e4 1.49e4 1.49e4	50.00 50.00 50.00	AEIR AEIR AEIR
UBERON:0002424	oral epithelium	[+] 1 stage ZFS:0000036Larval:Day 4	1.49e4 1.49e4	50.00 50.00	AEIR AEIR
UBERON:0003351	pharyngeal epithelium	[+] 2 stages ZFS:0000037Larval:Day 5 ZFS:0000039Larval:Days 7-13	1.49e4 1.49e4 1.49e4	50.00 50.00 50.00	AEIR AEIR AEIR
UBERON:0001791	inner nuclear layer of retina	[+] 1 stage ZFS:0000036Larval:Day 4	1.49e4 1.49e4	50.00 50.00	AEIR AEIR
UBERON:0001944	pretectal region	[+] 3 stages ZFS:0000036Larval:Day 4 ZFS:0000033Hatching:Long-pec ZFS:0000035Larval:Protruding-mouth	1.49e4 1.49e4 1.49e4 1.49e4	50.00 50.00 50.00 50.00	AEIR AEIR AEIR AEIR
UBERON:2000228	lateral line primordium	[+] 1 stage ZFS:0000029Pharyngula:Prim-5	1.49e4 1.49e4	50.00 50.00	AEIR AEIR
UBERON:2001431	primitive olfactory epithelium	[+] 1 stage ZFS:0000029Pharyngula:Prim-5	1.49e4 1.49e4	49.99 49.99	AEIR AEIR
UBERON:0005068	neural rod	[+] 1 stage ZFS:0000024Segmentation:5-9 somites	1.49e4 1.49e4	49.99 49.99	AEIR AEIR
UBERON:0003069	otic placode	[+] 1 stage ZFS:0000024Segmentation:5-9 somites	1.49e4 1.49e4	49.98 49.98	AEIR AEIR
UBERON:0000007	pituitary gland	[+] 1 stage ZFS:0000029Pharyngula:Prim-5	1.49e4 1.49e4	49.98 49.98	AEIR AEIR
UBERON:0000473	testis	[+] 2 stages UBERON:0000104life cycle UBERON:0000066fully formed stage	1.50e4 1.50e4 2.04e4	49.92 49.92 31.75	AEIR AEIR AEIR
UBERON:0019248	early embryo	[+] 1 stage UBERON:0000107cleavage stage	1.63e4 1.63e4	45.56 45.56	AEIR AEIR
UBERON:0002481	bone tissue	[+] 1 stage UBERON:0000066fully formed stage	1.66e4 1.66e4	44.40 44.40	AEIR AEIR
UBERON:0002199	integument	[+] 1 stage UBERON:0000066fully formed stage	1.68e4 1.68e4	43.61 43.61	AEIR AEIR
UBERON:0000992	female gonad	[+] 1 stage UBERON:0000066fully formed stage	1.77e4 1.77e4	40.80 40.80	AEIR AEIR
UBERON:0000206	pharyngeal gill	[+] 1 stage UBERON:0000066fully formed stage	1.88e4 1.88e4	37.14 37.14	AEIR AEIR
UBERON:0000014	zone of skin	[+] 1 stage UBERON:0000066fully formed stage	2.06e4 2.06e4	31.18 31.18	AEIR AEIR
UBERON:0002415	tail	[+] 1 stage UBERON:0000066fully formed stage	2.21e4 2.21e4	25.94 25.94	AEIR AEIR

Sources
A	Affymetrix
E	EST
I	In Situ
R	RNA-Seq

data

no data

Rank scores
3.25e4	lightgrey: low confidence scores
	important score variation

Rank scores of expression calls are normalized across genes, conditions and species. Low score means that the gene is highly expressed in the condition. Max rank score in all species: 4.10e4. Min rank score varies across species.

Expression scores of expression calls use the minimum and maximum Rank of the species to normalize the expression to a value between 0 and 100. Low score means that the gene is lowly expressed in the condition.

Sources of annotations to anatomy and development:

Affymetrix data: Bgee
EST data: Bgee
In situ hybridization data: ZFIN
RNA-Seq data: Bgee

Sources of raw data:

Affymetrix data: ArrayExpress, GEO
EST data: UniGene
In situ hybridization data: ZFIN
RNA-Seq data: GEO

Orthologs

Taxon name	Species with orthologs	Gene(s)	Expression comparison	See details
Euteleostomi	18 species Homo sapiens (human) Mus musculus (mouse) Pan troglodytes (chimpanzee) Gorilla gorilla (gorilla) Macaca mulatta (macaque) Rattus norvegicus (rat) Bos taurus (cattle) Sus scrofa (pig) Equus caballus (horse) Oryctolagus cuniculus (rabbit) Canis lupus familiaris (dog) Felis catus (cat) Cavia porcellus (guinea pig) Erinaceus europaeus (hedgehog) Monodelphis domestica (opossum) Gallus gallus (chicken) Anolis carolinensis (green anole) Xenopus tropicalis (western clawed frog)	18 genes ENSG00000176697 BDNF ENSMUSG00000048482 Bdnf ENSPTRG00000040882 ENSGGOG00000022171 BDNF ENSMMUG00000008634 BDNF ENSRNOG00000047466 Bdnf ENSBTAG00000008134 BDNF ENSSSCG00000013333 BDNF ENSECAG00000015952 BDNF ENSOCUG00000006731 BDNF ENSCAFG00000010207 BDNF ENSFCAG00000011653 BDNF ENSCPOG00000009920 BDNF ENSEEUG00000005994 BDNF ENSMODG00000009461 BDNF ENSGALG00000012163 BDNF ENSACAG00000015738 BDNF ENSXETG00000004284 bdnf	Compare expression	[+]

Orthology information comes from OMA : ENSDARG00000018817.

Cross-references

Ensembl	ENSDARG00000018817 (bdnf)
ZFIN	ZDB-GENE-000412-1 (bdnf)
EMBL	AL935207, BC058301, BC066399, BC066468, CU459028
Uniprot/SPTREMBL	B0V301, B0V301_DANRE, E9QIT5, E9QIT5_DANRE, F1Q5K0, F1Q5K0_DANRE, Q6NZ01, Q6NZ01_DANRE