D. rerio Gene: llgl2 - ENSDARG00000023920 - Danio rerio (zebrafish)

General information

Ensembl IDENSDARG00000023920
Namellgl2
Descriptionlethal giant larvae homolog 2 (Drosophila) [Source:ZFIN;Acc:ZDB-GENE-030131-9877]
OrganismDanio rerio (zebrafish)
Synonym(s)cb521, lgl2, llglh2, pen, penner, sb:cb521, wu:fc06g08, wu:fl37c09, zgc:55895
Orthologs(s)24 orthologs
Paralog(s)1 paralogs

Expression

Anat. entity IDAnatomical entityDevelopmental stage(s)Rank scoreExpression scoreSources
UBERON:0007010cleaving embryo
  • ZFS:0000005Cleavage:16-cell
512
  • 512
98.29
  • 98.29
AEIR
  • AEIR
UBERON:0000307blastula
  • ZFS:0000011Blastula:1k-cell
  • ZFS:0000015Blastula:Dome
  • ZFS:0000016Blastula:30%-epiboly
  • ZFS:0000014Blastula:Sphere
  • ZFS:0000009Blastula:256-cell
587
  • 587
  • 657
  • 2.22e3
  • 2.93e3
  • 3.48e3
98.04
  • 98.04
  • 97.80
  • 92.56
  • 90.19
  • 88.34
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0000468multi-cellular organism
  • UBERON:0000106zygote stage
  • ZFS:0000019Gastrula:Shield
  • ZFS:0000020Gastrula:75%-epiboly
  • ZFS:0000022Gastrula:Bud
  • ZFS:0000021Gastrula:90%-epiboly
  • ZFS:0000040Larval:Days 14-20
  • ZFS:0000029Pharyngula:Prim-5
  • ZFS:0000026Segmentation:14-19 somites
  • ZFS:0000024Segmentation:5-9 somites
  • ZFS:0000028Segmentation:26+ somites
  • ZFS:0000036Larval:Day 4
  • ZFS:0000030Pharyngula:Prim-15
  • ZFS:0000042Juvenile:Days 30-44
  • ZFS:0000033Hatching:Long-pec
  • ZFS:0000037Larval:Day 5
  • UBERON:00072322 cell stage
  • UBERON:0000104life cycle
  • UBERON:0000066fully formed stage
  • UBERON:0000068embryo stage
1.05e3
  • 1.05e3
  • 1.14e3
  • 3.07e3
  • 3.41e3
  • 3.50e3
  • 3.73e3
  • 3.97e3
  • 4.08e3
  • 4.19e3
  • 4.27e3
  • 4.36e3
  • 4.64e3
  • 4.67e3
  • 5.28e3
  • 6.03e3
  • 6.79e3
  • 1.44e4
  • 1.45e4
  • 1.46e4
96.49
  • 96.49
  • 96.19
  • 89.72
  • 88.60
  • 88.29
  • 87.50
  • 86.72
  • 86.33
  • 85.99
  • 85.71
  • 85.39
  • 84.46
  • 84.36
  • 82.33
  • 79.81
  • 77.27
  • 51.88
  • 51.56
  • 51.01
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0019248early embryo
  • UBERON:0000107cleavage stage
1.09e3
  • 1.09e3
96.37
  • 96.37
AEIR
  • AEIR
UBERON:0004734gastrula
  • ZFS:0000019Gastrula:Shield
  • ZFS:0000017Gastrula:50%-epiboly
  • UBERON:0000109gastrula stage
  • ZFS:0000022Gastrula:Bud
  • ZFS:0000021Gastrula:90%-epiboly
  • ZFS:0000020Gastrula:75%-epiboly
1.17e3
  • 1.17e3
  • 1.93e3
  • 2.60e3
  • 3.09e3
  • 3.32e3
  • 4.34e3
96.10
  • 96.10
  • 93.55
  • 91.30
  • 89.66
  • 88.88
  • 85.47
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0000206pharyngeal gill
  • UBERON:0000066fully formed stage
1.52e3
  • 1.52e3
94.93
  • 94.93
AEIR
  • AEIR
UBERON:0000970eye
  • ZFS:0000031Pharyngula:Prim-25
2.24e3
  • 2.24e3
92.49
  • 92.49
AEIR
  • AEIR
UBERON:0000160intestine
  • UBERON:0000066fully formed stage
2.27e3
  • 2.27e3
92.40
  • 92.40
AEIR
  • AEIR
UBERON:0002415tail
  • UBERON:0000066fully formed stage
2.43e3
  • 2.43e3
91.85
  • 91.85
AEIR
  • AEIR
UBERON:2000001Kupffer's vesicle
  • ZFS:0000023Segmentation:1-4 somites
  • ZFS:0000024Segmentation:5-9 somites
  • ZFS:0000025Segmentation:10-13 somites
  • ZFS:0000026Segmentation:14-19 somites
2.49e3
  • 2.49e3
  • 4.60e3
  • 4.60e3
  • 1.12e4
91.67
  • 91.67
  • 84.61
  • 84.61
  • 62.49
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0000922embryo
  • UBERON:0004707pharyngula stage
  • UBERON:0000068embryo stage
  • ZFS:0000026Segmentation:14-19 somites
  • ZFS:0000025Segmentation:10-13 somites
  • ZFS:0000029Pharyngula:Prim-5
  • ZFS:0000024Segmentation:5-9 somites
  • ZFS:0000037Larval:Day 5
  • ZFS:0000033Hatching:Long-pec
  • ZFS:0000030Pharyngula:Prim-15
  • ZFS:0000031Pharyngula:Prim-25
2.77e3
  • 2.77e3
  • 3.09e3
  • 3.72e3
  • 3.76e3
  • 3.89e3
  • 4.03e3
  • 4.15e3
  • 4.26e3
  • 5.31e3
  • 8.34e3
90.73
  • 90.73
  • 89.66
  • 87.55
  • 87.41
  • 86.98
  • 86.50
  • 86.12
  • 85.74
  • 82.21
  • 72.07
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0002113kidney
  • UBERON:0000066fully formed stage
2.95e3
  • 2.95e3
90.14
  • 90.14
AEIR
  • AEIR
UBERON:4000164caudal fin
  • UBERON:0000066fully formed stage
  • ZFS:0000033Hatching:Long-pec
3.03e3
  • 3.03e3
  • 3.21e3
89.86
  • 89.86
  • 89.25
AEIR
  • AEIR
  • AEIR
UBERON:0000033head
  • UBERON:0000066fully formed stage
  • ZFS:0000037Larval:Day 5
3.16e3
  • 3.16e3
  • 5.28e3
89.44
  • 89.44
  • 82.31
AEIR
  • AEIR
  • AEIR
UBERON:0000014zone of skin
  • UBERON:0000066fully formed stage
3.35e3
  • 3.35e3
88.78
  • 88.78
AEIR
  • AEIR
UBERON:0002106spleen
  • UBERON:0000066fully formed stage
3.95e3
  • 3.95e3
86.77
  • 86.77
AEIR
  • AEIR
UBERON:0002548larva
  • UBERON:0000069larval stage
  • ZFS:0000037Larval:Day 5
  • ZFS:0000035Larval:Protruding-mouth
4.07e3
  • 4.07e3
  • 5.11e3
  • 5.84e3
86.37
  • 86.37
  • 82.89
  • 80.46
AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0007383enveloping layer of ectoderm
  • ZFS:0000020Gastrula:75%-epiboly
  • ZFS:0000017Gastrula:50%-epiboly
  • ZFS:0000018Gastrula:Germ-ring
  • ZFS:0000021Gastrula:90%-epiboly
  • ZFS:0000022Gastrula:Bud
  • ZFS:0000019Gastrula:Shield
4.07e3
  • 4.07e3
  • 5.43e3
  • 5.97e3
  • 5.97e3
  • 5.97e3
  • 6.22e3
86.36
  • 86.36
  • 81.81
  • 80.00
  • 80.00
  • 80.00
  • 79.16
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0000948heart
  • UBERON:0000066fully formed stage
  • ZFS:0000036Larval:Day 4
4.09e3
  • 4.09e3
  • 5.07e3
86.32
  • 86.32
  • 83.04
AEIR
  • AEIR
  • AEIR
UBERON:0002107liver
  • UBERON:0000066fully formed stage
4.12e3
  • 4.12e3
86.19
  • 86.19
AEIR
  • AEIR
UBERON:0003982mature ovarian follicle
  • UBERON:0000066fully formed stage
4.38e3
  • 4.38e3
85.35
  • 85.35
AEIR
  • AEIR
UBERON:0000966retina
  • ZFS:0000037Larval:Day 5
  • UBERON:0000066fully formed stage
  • ZFS:0000031Pharyngula:Prim-25
  • ZFS:0000033Hatching:Long-pec
4.81e3
  • 4.81e3
  • 7.41e3
  • 7.86e3
  • 8.12e3
83.90
  • 83.90
  • 75.21
  • 73.69
  • 72.82
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
CL:0000094granulocyte
  • UBERON:0000066fully formed stage
5.29e3
  • 5.29e3
82.28
  • 82.28
AEIR
  • AEIR
UBERON:0002082cardiac ventricle
  • UBERON:0000066fully formed stage
5.32e3
  • 5.32e3
82.20
  • 82.20
AEIR
  • AEIR
UBERON:0002481bone tissue
  • UBERON:0000066fully formed stage
5.43e3
  • 5.43e3
81.81
  • 81.81
AEIR
  • AEIR
UBERON:0009620tail bud paraxial mesoderm
  • ZFS:0000027Segmentation:20-25 somites
5.53e3
  • 5.53e3
81.50
  • 81.50
AEIR
  • AEIR
UBERON:0000955brain
  • ZFS:0000031Pharyngula:Prim-25
  • UBERON:0000066fully formed stage
5.64e3
  • 5.64e3
  • 8.95e3
81.11
  • 81.11
  • 70.02
AEIR
  • AEIR
  • AEIR
UBERON:0002385muscle tissue
  • UBERON:0000066fully formed stage
5.78e3
  • 5.78e3
80.64
  • 80.64
AEIR
  • AEIR
UBERON:0007132head kidney
  • UBERON:0000066fully formed stage
5.78e3
  • 5.78e3
80.64
  • 80.64
AEIR
  • AEIR
UBERON:0001630muscle organ
  • UBERON:0000066fully formed stage
5.97e3
  • 5.97e3
80.02
  • 80.02
AEIR
  • AEIR
UBERON:2000058polster
  • ZFS:0000023Segmentation:1-4 somites
  • ZFS:0000025Segmentation:10-13 somites
  • ZFS:0000024Segmentation:5-9 somites
6.64e3
  • 6.64e3
  • 6.64e3
  • 7.47e3
77.77
  • 77.77
  • 77.77
  • 74.99
AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0003059presomitic mesoderm
  • ZFS:0000025Segmentation:10-13 somites
7.03e3
  • 7.03e3
76.46
  • 76.46
AEIR
  • AEIR
UBERON:0003069otic placode
  • ZFS:0000026Segmentation:14-19 somites
  • ZFS:0000025Segmentation:10-13 somites
  • ZFS:0000023Segmentation:1-4 somites
  • ZFS:0000024Segmentation:5-9 somites
7.08e3
  • 7.08e3
  • 1.12e4
  • 1.15e4
  • 1.22e4
76.30
  • 76.30
  • 62.49
  • 61.53
  • 59.08
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0002329somite
  • ZFS:0000025Segmentation:10-13 somites
7.21e3
  • 7.21e3
75.85
  • 75.85
AEIR
  • AEIR
UBERON:0003058hypochord
  • ZFS:0000029Pharyngula:Prim-5
  • ZFS:0000028Segmentation:26+ somites
  • ZFS:0000027Segmentation:20-25 somites
7.47e3
  • 7.47e3
  • 8.04e3
  • 8.71e3
74.99
  • 74.99
  • 73.07
  • 70.82
AEIR
  • AEIR
  • AEIR
  • AEIR
ZFA:0000003adaxial cell (Danio)
  • ZFS:0000026Segmentation:14-19 somites
7.47e3
  • 7.47e3
74.99
  • 74.99
AEIR
  • AEIR
ZFA:0000023forerunner cell group (Danio)
  • ZFS:0000020Gastrula:75%-epiboly
  • ZFS:0000019Gastrula:Shield
  • ZFS:0000021Gastrula:90%-epiboly
  • ZFS:0000017Gastrula:50%-epiboly
  • ZFS:0000018Gastrula:Germ-ring
  • ZFS:0000022Gastrula:Bud
7.47e3
  • 7.47e3
  • 8.04e3
  • 8.04e3
  • 8.15e3
  • 8.15e3
  • 8.54e3
74.99
  • 74.99
  • 73.07
  • 73.07
  • 72.72
  • 72.72
  • 71.42
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0003060pronephric duct
  • ZFS:0000029Pharyngula:Prim-5
  • ZFS:0000027Segmentation:20-25 somites
  • ZFS:0000026Segmentation:14-19 somites
  • ZFS:0000028Segmentation:26+ somites
  • ZFS:0000030Pharyngula:Prim-15
  • ZFS:0000031Pharyngula:Prim-25
7.47e3
  • 7.47e3
  • 8.96e3
  • 9.13e3
  • 9.44e3
  • 1.12e4
  • 1.12e4
74.99
  • 74.99
  • 69.98
  • 69.43
  • 68.40
  • 62.48
  • 62.48
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0006860swim bladder
  • UBERON:0000066fully formed stage
7.75e3
  • 7.75e3
74.07
  • 74.07
AEIR
  • AEIR
UBERON:0003051ear vesicle
  • ZFS:0000027Segmentation:20-25 somites
  • ZFS:0000029Pharyngula:Prim-5
  • ZFS:0000028Segmentation:26+ somites
  • ZFS:0000032Pharyngula:High-pec
  • ZFS:0000030Pharyngula:Prim-15
  • ZFS:0000033Hatching:Long-pec
  • ZFS:0000031Pharyngula:Prim-25
7.80e3
  • 7.80e3
  • 8.47e3
  • 9.25e3
  • 9.44e3
  • 9.71e3
  • 9.71e3
  • 1.02e4
73.90
  • 73.90
  • 71.64
  • 69.03
  • 68.40
  • 67.48
  • 67.48
  • 65.89
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0001638vein
  • ZFS:0000027Segmentation:20-25 somites
  • ZFS:0000028Segmentation:26+ somites
  • ZFS:0000029Pharyngula:Prim-5
8.04e3
  • 8.04e3
  • 8.04e3
  • 8.96e3
73.07
  • 73.07
  • 73.07
  • 69.99
AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0003050olfactory placode
  • ZFS:0000029Pharyngula:Prim-5
  • ZFS:0000026Segmentation:14-19 somites
  • ZFS:0000027Segmentation:20-25 somites
  • ZFS:0000028Segmentation:26+ somites
8.22e3
  • 8.22e3
  • 8.40e3
  • 9.13e3
  • 9.13e3
72.48
  • 72.48
  • 71.86
  • 69.43
  • 69.43
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0003055periderm
  • ZFS:0000017Gastrula:50%-epiboly
  • ZFS:0000018Gastrula:Germ-ring
  • ZFS:0000019Gastrula:Shield
  • ZFS:0000020Gastrula:75%-epiboly
  • ZFS:0000021Gastrula:90%-epiboly
  • ZFS:0000022Gastrula:Bud
8.53e3
  • 8.53e3
  • 8.53e3
  • 8.53e3
  • 8.53e3
  • 8.53e3
  • 8.53e3
71.43
  • 71.43
  • 71.43
  • 71.43
  • 71.43
  • 71.43
  • 71.43
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0000473testis
  • UBERON:0000066fully formed stage
9.12e3
  • 9.12e3
69.47
  • 69.47
AEIR
  • AEIR
UBERON:0002540lateral line system
  • ZFS:0000027Segmentation:20-25 somites
  • ZFS:0000028Segmentation:26+ somites
  • ZFS:0000029Pharyngula:Prim-5
  • ZFS:0000032Pharyngula:High-pec
  • ZFS:0000033Hatching:Long-pec
9.13e3
  • 9.13e3
  • 9.13e3
  • 9.13e3
  • 1.12e4
  • 1.12e4
69.43
  • 69.43
  • 69.43
  • 69.43
  • 62.49
  • 62.49
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0000004nose
  • ZFS:0000033Hatching:Long-pec
  • ZFS:0000032Pharyngula:High-pec
  • ZFS:0000030Pharyngula:Prim-15
  • ZFS:0000031Pharyngula:Prim-25
9.34e3
  • 9.34e3
  • 9.67e3
  • 1.14e4
  • 1.14e4
68.74
  • 68.74
  • 67.63
  • 61.75
  • 61.75
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0002037cerebellum
  • ZFS:0000033Hatching:Long-pec
  • ZFS:0000032Pharyngula:High-pec
1.07e4
  • 1.07e4
  • 1.22e4
64.27
  • 64.27
  • 59.08
AEIR
  • AEIR
  • AEIR
UBERON:0001555digestive tract
  • ZFS:0000029Pharyngula:Prim-5
  • ZFS:0000030Pharyngula:Prim-15
  • ZFS:0000031Pharyngula:Prim-25
1.10e4
  • 1.10e4
  • 1.15e4
  • 1.17e4
63.32
  • 63.32
  • 61.53
  • 60.70
AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0001042chordate pharynx
  • ZFS:0000033Hatching:Long-pec
  • ZFS:0000032Pharyngula:High-pec
1.12e4
  • 1.12e4
  • 1.16e4
62.48
  • 62.48
  • 61.09
AEIR
  • AEIR
  • AEIR
UBERON:2001157posterior lateral line primordium
  • ZFS:0000029Pharyngula:Prim-5
  • ZFS:0000030Pharyngula:Prim-15
1.24e4
  • 1.24e4
  • 1.36e4
58.33
  • 58.33
  • 54.53
AEIR
  • AEIR
  • AEIR
UBERON:0001003skin epidermis
  • ZFS:0000029Pharyngula:Prim-5
1.28e4
  • 1.28e4
57.12
  • 57.12
AEIR
  • AEIR
Sources
AAffymetrix
EEST
IIn Situ
RRNA-Seq
data
no data
Rank scores
3.25e4lightgrey: low confidence scores
 important score variation

Rank scores of expression calls are normalized across genes, conditions and species. Low score means that the gene is highly expressed in the condition. Max rank score in all species: 4.10e4. Min rank score varies across species.

Expression scores of expression calls use the minimum and maximum Rank of the species to normalize the expression to a value between 0 and 100. Low score means that the gene is lowly expressed in the condition.

Sources of annotations to anatomy and development:
  • Affymetrix data: Bgee
  • EST data: Bgee
  • In situ hybridization data: ZFIN
  • RNA-Seq data: Bgee
Sources of raw data:

Orthologs
Taxon nameSpecies with orthologsGene(s)Expression comparisonSee details
Euteleostomi17 species17 genesCompare expression
Bilateria24 species24 genesCompare expression

Orthology information comes from OMA : ENSDARG00000023920.

Paralogs (same species)
Taxon nameGene(s)Expression comparisonSee details
Chordata1 geneCompare expression

Paralogy information comes from OMA : ENSDARG00000023920.

Cross-references

EnsemblENSDARG00000023920 (llgl2)
ZFINZDB-GENE-030131-9877 (llgl2)
EMBLBC052919, BC171635, CR405682, CU462818, FQ312018
Uniprot/SPTREMBLB7ZVM2, B7ZVM2_DANRE, G1K2W2, G1K2W2_DANRE
Uniprot/SWISSPROTL2GL2_DANRE, Q7SZE3

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