Gene: slc6a1b - ENSDARG00000039647 - Danio rerio (zebrafish)

General information

Ensembl ID	ENSDARG00000039647
Name	slc6a1b
Description	solute carrier family 6 (neurotransmitter transporter), member 1b [Source:ZFIN;Acc:ZDB-GENE-041114-57]
Organism	Danio rerio (zebrafish)
Synonym(s)	gat-1, slc6a1, wu:fj45h10, wu:fq41d04, zgc:103663, zgc:103663gn
Orthologs(s)	3 orthologs
Paralog(s)	29 paralogs

Expression

Anat. entity ID	Anatomical entity	Developmental stage(s)	Rank score	Expression score	Sources
UBERON:0000468	multi-cellular organism	[+] 9 stages ZFS:0000037Larval:Day 5 ZFS:0000036Larval:Day 4 ZFS:0000040Larval:Days 14-20 ZFS:0000033Hatching:Long-pec ZFS:0000042Juvenile:Days 30-44 ZFS:0000030Pharyngula:Prim-15 UBERON:0000106zygote stage ZFS:0000029Pharyngula:Prim-5 ZFS:0000026Segmentation:14-19 somites	388 388 645 1.20e3 2.15e3 2.59e3 7.36e3 1.11e4 1.16e4 1.34e4	98.71 98.71 97.84 96.00 92.80 91.31 75.36 62.91 61.12 55.24	AEIR AEIR AEIR AEIR AEIR AEIR AEIR AEIR AEIR AEIR
UBERON:0000955	brain	[+] 5 stages UBERON:0000066fully formed stage ZFS:0000037Larval:Day 5 ZFS:0000033Hatching:Long-pec ZFS:0000031Pharyngula:Prim-25 ZFS:0000035Larval:Protruding-mouth	405 405 2.99e3 6.79e3 8.65e3 9.51e3	98.65 98.65 90.00 77.27 71.03 68.17	AEIR AEIR AEIR AEIR AEIR AEIR
UBERON:0000033	head	[+] 2 stages ZFS:0000037Larval:Day 5 UBERON:0000066fully formed stage	603 603 1.95e3	97.98 97.98 93.47	AEIR AEIR AEIR
UBERON:0000966	retina	[+] 4 stages ZFS:0000037Larval:Day 5 ZFS:0000033Hatching:Long-pec ZFS:0000031Pharyngula:Prim-25 UBERON:0000066fully formed stage	675 675 4.31e3 8.64e3 8.88e3	97.74 97.74 85.55 71.07 70.27	AEIR AEIR AEIR AEIR AEIR
UBERON:0002548	larva	[+] 3 stages ZFS:0000035Larval:Protruding-mouth ZFS:0000037Larval:Day 5 UBERON:0000069larval stage	796 796 2.10e3 3.19e3	97.34 97.34 92.97 89.34	AEIR AEIR AEIR AEIR
UBERON:0000922	embryo	[+] 7 stages ZFS:0000037Larval:Day 5 ZFS:0000033Hatching:Long-pec ZFS:0000031Pharyngula:Prim-25 UBERON:0000068embryo stage ZFS:0000030Pharyngula:Prim-15 UBERON:0004707pharyngula stage ZFS:0000029Pharyngula:Prim-5	948 948 1.66e3 2.79e3 8.76e3 1.06e4 1.42e4 1.47e4	96.83 96.83 94.46 90.65 70.67 64.44 52.54 50.78	AEIR AEIR AEIR AEIR AEIR AEIR AEIR AEIR
UBERON:0001792	ganglionic layer of retina	[+] 1 stage ZFS:0000037Larval:Day 5	4.27e3 4.27e3	85.71 85.71	AEIR AEIR
UBERON:0001945	superior colliculus	[+] 2 stages ZFS:0000032Pharyngula:High-pec ZFS:0000033Hatching:Long-pec	7.03e3 7.03e3 7.08e3	76.46 76.46 76.30	AEIR AEIR AEIR
UBERON:0001893	telencephalon	[+] 7 stages ZFS:0000027Segmentation:20-25 somites ZFS:0000028Segmentation:26+ somites ZFS:0000029Pharyngula:Prim-5 ZFS:0000033Hatching:Long-pec ZFS:0000032Pharyngula:High-pec ZFS:0000030Pharyngula:Prim-15 ZFS:0000031Pharyngula:Prim-25	7.08e3 7.08e3 7.47e3 8.09e3 8.30e3 8.40e3 9.44e3 9.44e3	76.30 76.30 74.99 72.90 72.21 71.86 68.40 68.40	AEIR AEIR AEIR AEIR AEIR AEIR AEIR AEIR
UBERON:0001891	midbrain	[+] 5 stages ZFS:0000030Pharyngula:Prim-15 ZFS:0000031Pharyngula:Prim-25 ZFS:0000033Hatching:Long-pec ZFS:0000032Pharyngula:High-pec ZFS:0000026Segmentation:14-19 somites	7.47e3 7.47e3 7.91e3 7.97e3 8.54e3 8.54e3	74.99 74.99 73.52 73.32 71.42 71.41	AEIR AEIR AEIR AEIR AEIR AEIR
UBERON:0002028	hindbrain	[+] 8 stages ZFS:0000027Segmentation:20-25 somites ZFS:0000028Segmentation:26+ somites ZFS:0000033Hatching:Long-pec ZFS:0000032Pharyngula:High-pec ZFS:0000030Pharyngula:Prim-15 ZFS:0000029Pharyngula:Prim-5 ZFS:0000031Pharyngula:Prim-25 ZFS:0000026Segmentation:14-19 somites	7.83e3 7.83e3 8.22e3 8.22e3 8.65e3 8.96e3 9.07e3 9.10e3 9.71e3	73.79 73.79 72.48 72.48 71.04 69.98 69.62 69.55 67.48	AEIR AEIR AEIR AEIR AEIR AEIR AEIR AEIR AEIR
UBERON:0002240	spinal cord	[+] 7 stages ZFS:0000032Pharyngula:High-pec ZFS:0000027Segmentation:20-25 somites ZFS:0000028Segmentation:26+ somites ZFS:0000029Pharyngula:Prim-5 ZFS:0000033Hatching:Long-pec ZFS:0000030Pharyngula:Prim-15 ZFS:0000031Pharyngula:Prim-25	7.91e3 7.91e3 8.22e3 8.22e3 8.54e3 8.65e3 8.83e3 9.51e3	73.52 73.52 72.48 72.48 71.41 71.04 70.44 68.16	AEIR AEIR AEIR AEIR AEIR AEIR AEIR AEIR
UBERON:0001890	forebrain	[+] 4 stages ZFS:0000033Hatching:Long-pec ZFS:0000031Pharyngula:Prim-25 ZFS:0000032Pharyngula:High-pec ZFS:0000030Pharyngula:Prim-15	7.97e3 7.97e3 8.04e3 8.54e3 9.19e3	73.32 73.32 73.07 71.42 69.22	AEIR AEIR AEIR AEIR AEIR
UBERON:0001894	diencephalon	[+] 8 stages ZFS:0000026Segmentation:14-19 somites ZFS:0000033Hatching:Long-pec ZFS:0000027Segmentation:20-25 somites ZFS:0000028Segmentation:26+ somites ZFS:0000029Pharyngula:Prim-5 ZFS:0000032Pharyngula:High-pec ZFS:0000030Pharyngula:Prim-15 ZFS:0000031Pharyngula:Prim-25	8.30e3 8.30e3 8.30e3 8.45e3 8.65e3 8.72e3 8.79e3 9.10e3 9.51e3	72.21 72.21 72.21 71.72 71.04 70.81 70.57 69.55 68.16	AEIR AEIR AEIR AEIR AEIR AEIR AEIR AEIR AEIR
UBERON:0001943	midbrain tegmentum	[+] 7 stages ZFS:0000029Pharyngula:Prim-5 ZFS:0000032Pharyngula:High-pec ZFS:0000033Hatching:Long-pec ZFS:0000027Segmentation:20-25 somites ZFS:0000028Segmentation:26+ somites ZFS:0000030Pharyngula:Prim-15 ZFS:0000031Pharyngula:Prim-25	8.30e3 8.30e3 8.40e3 8.40e3 8.79e3 8.79e3 9.34e3 9.67e3	72.21 72.21 71.86 71.86 70.57 70.57 68.74 67.63	AEIR AEIR AEIR AEIR AEIR AEIR AEIR AEIR
UBERON:0010285	midbrain basal plate	[+] 3 stages ZFS:0000027Segmentation:20-25 somites ZFS:0000028Segmentation:26+ somites ZFS:0000029Pharyngula:Prim-5	8.79e3 8.79e3 8.79e3 8.79e3	70.57 70.57 70.57 70.57	AEIR AEIR AEIR AEIR
CL:0000540	neuron	[+] 8 stages ZFS:0000027Segmentation:20-25 somites ZFS:0000028Segmentation:26+ somites ZFS:0000026Segmentation:14-19 somites ZFS:0000030Pharyngula:Prim-15 ZFS:0000031Pharyngula:Prim-25 ZFS:0000029Pharyngula:Prim-5 ZFS:0000032Pharyngula:High-pec ZFS:0000033Hatching:Long-pec	8.96e3 8.96e3 8.96e3 9.19e3 9.34e3 9.34e3 9.51e3 9.60e3 9.96e3	69.98 69.98 69.98 69.22 68.74 68.74 68.16 67.85 66.65	AEIR AEIR AEIR AEIR AEIR AEIR AEIR AEIR AEIR
UBERON:0002481	bone tissue	[+] 1 stage UBERON:0000066fully formed stage	1.03e4 1.03e4	65.50 65.50	AEIR AEIR
UBERON:4000164	caudal fin	[+] 2 stages ZFS:0000033Hatching:Long-pec UBERON:0000066fully formed stage	1.07e4 1.07e4 1.33e4	64.26 64.26 55.63	AEIR AEIR AEIR
UBERON:0000307	blastula	[+] 1 stage ZFS:0000009Blastula:256-cell	1.21e4 1.21e4	59.56 59.56	AEIR AEIR
UBERON:0002199	integument	[+] 1 stage UBERON:0000066fully formed stage	1.21e4 1.21e4	59.55 59.55	AEIR AEIR
UBERON:0001630	muscle organ	[+] 1 stage UBERON:0000066fully formed stage	1.25e4 1.25e4	58.26 58.26	AEIR AEIR
UBERON:0002385	muscle tissue	[+] 1 stage UBERON:0000066fully formed stage	1.25e4 1.25e4	58.24 58.24	AEIR AEIR
UBERON:0009620	tail bud paraxial mesoderm	[+] 1 stage ZFS:0000027Segmentation:20-25 somites	1.26e4 1.26e4	57.67 57.67	AEIR AEIR
UBERON:0000992	female gonad	[+] 1 stage UBERON:0000066fully formed stage	1.63e4 1.63e4	45.52 45.52	AEIR AEIR
UBERON:0000948	heart	[+] 1 stage ZFS:0000036Larval:Day 4	1.70e4 1.70e4	43.24 43.24	AEIR AEIR
UBERON:0000473	testis	[+] 1 stage UBERON:0000066fully formed stage	1.89e4 1.89e4	36.74 36.74	AEIR AEIR
UBERON:0002107	liver	[+] 1 stage UBERON:0000066fully formed stage	1.93e4 1.93e4	35.49 35.49	AEIR AEIR
UBERON:0000014	zone of skin	[+] 1 stage UBERON:0000066fully formed stage	1.94e4 1.94e4	34.96 34.96	AEIR AEIR

Sources
A	Affymetrix
E	EST
I	In Situ
R	RNA-Seq

data

no data

Rank scores
3.25e4	lightgrey: low confidence scores
	important score variation

Rank scores of expression calls are normalized across genes, conditions and species. Low score means that the gene is highly expressed in the condition. Max rank score in all species: 4.10e4. Min rank score varies across species.

Expression scores of expression calls use the minimum and maximum Rank of the species to normalize the expression to a value between 0 and 100. Low score means that the gene is lowly expressed in the condition.

Sources of annotations to anatomy and development:

Affymetrix data: Bgee
In situ hybridization data: ZFIN
RNA-Seq data: Bgee

Sources of raw data:

Affymetrix data: ArrayExpress, GEO
In situ hybridization data: ZFIN
RNA-Seq data: GEO

Orthologs

Taxon name	Species with orthologs	Gene(s)	Expression comparison	See details
Euteleostomi	3 species Gallus gallus (chicken) Anolis carolinensis (green anole) Xenopus tropicalis (western clawed frog)	3 genes ENSGALG00000004921 SLC6A1 ENSACAG00000010020 SLC6A1 ENSXETG00000012105 XB-GENE-5944458	Compare expression	[+]

Orthology information comes from OMA : ENSDARG00000039647.

Paralogs (same species)

Taxon name	Gene(s)	Expression comparison	See details
Neopterygii	1 gene ENSDARG00000045944 slc6a1a	Compare expression	[+]
Chordata	2 genes ENSDARG00000041205 slc6a1l ENSDARG00000045944 slc6a1a	Compare expression	[+]
Deuterostomia	7 genes ENSDARG00000012534 slc6a6a ENSDARG00000041205 slc6a1l ENSDARG00000045944 slc6a1a ENSDARG00000067567 SLC6A13 ENSDARG00000071235 si:ch211-117c9.5 ENSDARG00000087981 slc6a11b ENSDARG00000098438 slc6a6b	Compare expression	[+]
Bilateria	11 genes ENSDARG00000000730 slc6a13 ENSDARG00000001354 slc6a13l ENSDARG00000012534 slc6a6a ENSDARG00000041205 slc6a1l ENSDARG00000043646 slc6a8 ENSDARG00000045944 slc6a1a ENSDARG00000067567 SLC6A13 ENSDARG00000071235 si:ch211-117c9.5 ENSDARG00000074002 slc6a11a ENSDARG00000087981 slc6a11b ENSDARG00000098438 slc6a6b	Compare expression	[+]
Eukaryota	29 genes ENSDARG00000000730 slc6a13 ENSDARG00000001354 slc6a13l ENSDARG00000002405 si:ch211-225b11.1 ENSDARG00000004219 SLC6A3 ENSDARG00000012534 slc6a6a ENSDARG00000016141 slc6a2 ENSDARG00000018534 slc6a9 ENSDARG00000018621 slc6a19a.1 ENSDARG00000029866 slc6a14 ENSDARG00000030006 SLC6A7 ENSDARG00000041205 slc6a1l ENSDARG00000043646 slc6a8 ENSDARG00000045944 slc6a1a ENSDARG00000046091 si:ch211-283g2.1 ENSDARG00000057017 slc6a4b ENSDARG00000061165 slc6a4a ENSDARG00000061480 si:ch211-132b12.1 ENSDARG00000062821 slc6a15 ENSDARG00000067567 SLC6A13 ENSDARG00000068363 si:ch211-132b12.3 ENSDARG00000068372 zgc:158427 ENSDARG00000068387 slc6a18 ENSDARG00000071235 si:ch211-117c9.5 ENSDARG00000074002 slc6a11a ENSDARG00000087981 slc6a11b ENSDARG00000091560 slc6a19a.2 ENSDARG00000094546 si:ch211-132b12.6 ENSDARG00000094946 si:ch211-132b12.2 ENSDARG00000098438 slc6a6b	Compare expression	[+]

Paralogy information comes from OMA : ENSDARG00000039647.

Cross-references

Ensembl	ENSDARG00000039647 (slc6a1b)
ZFIN	ZDB-GENE-041114-57 (slc6a1b)
EMBL	BC085579, CU633837, CU855911
Uniprot/SPTREMBL	Q5U3E5, Q5U3E5_DANRE