Gene: alox5a - ENSDARG00000057273 - Danio rerio (zebrafish)

General information

Ensembl ID	ENSDARG00000057273
Name	alox5a
Description	arachidonate 5-lipoxygenase a [Source:ZFIN;Acc:ZDB-GENE-090311-47]
Organism	Danio rerio (zebrafish)
Synonym(s)	alox5, lox2, si:dkey-194n13.2
Orthologs(s)	17 orthologs
Paralog(s)	6 paralogs

Expression

Anat. entity ID	Anatomical entity	Developmental stage(s)	Rank score	Expression score	Sources
CL:0000094	granulocyte	[+] 1 stage UBERON:0000066fully formed stage	1.57e3 1.57e3	94.74 94.74	AEIR AEIR
UBERON:0000206	pharyngeal gill	[+] 1 stage UBERON:0000066fully formed stage	6.64e3 6.64e3	77.77 77.77	AEIR AEIR
UBERON:0000468	multi-cellular organism	[+] 1 stage ZFS:0000011Blastula:1k-cell	6.79e3 6.79e3	77.27 77.27	AEIR AEIR
UBERON:0002106	spleen	[+] 1 stage UBERON:0000066fully formed stage	7.79e3 7.79e3	73.92 73.92	AEIR AEIR
UBERON:0007132	head kidney	[+] 1 stage UBERON:0000066fully formed stage	9.30e3 9.30e3	68.85 68.85	AEIR AEIR
UBERON:0002481	bone tissue	[+] 1 stage UBERON:0000066fully formed stage	1.05e4 1.05e4	64.91 64.91	AEIR AEIR
UBERON:0000922	embryo	[+] 5 stages UBERON:0000068embryo stage ZFS:0000033Hatching:Long-pec UBERON:0004707pharyngula stage ZFS:0000029Pharyngula:Prim-5 ZFS:0000037Larval:Day 5	1.24e4 1.24e4 1.31e4 1.50e4 1.52e4 2.16e4	58.64 58.64 56.11 49.70 49.14 27.65	AEIR AEIR AEIR AEIR AEIR AEIR
UBERON:0000014	zone of skin	[+] 1 stage UBERON:0000066fully formed stage	1.29e4 1.29e4	56.90 56.90	AEIR AEIR
UBERON:0003060	pronephric duct	[+] 1 stage ZFS:0000029Pharyngula:Prim-5	1.34e4 1.34e4	54.97 54.97	AEIR AEIR
UBERON:0000033	head	[+] 1 stage UBERON:0000066fully formed stage	1.38e4 1.38e4	53.78 53.78	AEIR AEIR
UBERON:0000160	intestine	[+] 1 stage UBERON:0000066fully formed stage	1.40e4 1.40e4	53.09 53.09	AEIR AEIR
UBERON:0000307	blastula	[+] 1 stage ZFS:0000015Blastula:Dome	1.41e4 1.41e4	52.80 52.80	AEIR AEIR
UBERON:0002385	muscle tissue	[+] 1 stage UBERON:0000066fully formed stage	1.42e4 1.42e4	52.62 52.62	AEIR AEIR
UBERON:0002107	liver	[+] 1 stage UBERON:0000066fully formed stage	1.52e4 1.52e4	48.94 48.94	AEIR AEIR
UBERON:0002415	tail	[+] 1 stage UBERON:0000066fully formed stage	1.62e4 1.62e4	45.88 45.88	AEIR AEIR
UBERON:0002548	larva	[+] 2 stages UBERON:0000069larval stage ZFS:0000037Larval:Day 5	1.62e4 1.62e4 2.17e4	45.85 45.85 27.30	AEIR AEIR AEIR
UBERON:0006860	swim bladder	[+] 1 stage UBERON:0000066fully formed stage	1.73e4 1.73e4	42.16 42.16	AEIR AEIR
UBERON:0004734	gastrula	[+] 1 stage ZFS:0000019Gastrula:Shield	1.76e4 1.76e4	40.94 40.94	AEIR AEIR
UBERON:0001630	muscle organ	[+] 1 stage UBERON:0000066fully formed stage	1.77e4 1.77e4	40.69 40.69	AEIR AEIR
UBERON:0000948	heart	[+] 2 stages UBERON:0000066fully formed stage ZFS:0000036Larval:Day 4	1.78e4 1.78e4 1.82e4	40.39 40.39 39.10	AEIR AEIR AEIR
UBERON:0000955	brain	[+] 1 stage UBERON:0000066fully formed stage	1.92e4 1.92e4	35.56 35.56	AEIR AEIR

Sources
A	Affymetrix
E	EST
I	In Situ
R	RNA-Seq

data

no data

Rank scores
3.25e4	lightgrey: low confidence scores
	important score variation

Rank scores of expression calls are normalized across genes, conditions and species. Low score means that the gene is highly expressed in the condition. Max rank score in all species: 4.10e4. Min rank score varies across species.

Expression scores of expression calls use the minimum and maximum Rank of the species to normalize the expression to a value between 0 and 100. Low score means that the gene is lowly expressed in the condition.

Sources of annotations to anatomy and development:

In situ hybridization data: ZFIN
RNA-Seq data: Bgee

Sources of raw data:

In situ hybridization data: ZFIN
RNA-Seq data: GEO

Orthologs

Taxon name	Species with orthologs	Gene(s)	Expression comparison	See details
Euteleostomi	17 species Homo sapiens (human) Mus musculus (mouse) Pan troglodytes (chimpanzee) Gorilla gorilla (gorilla) Macaca mulatta (macaque) Rattus norvegicus (rat) Bos taurus (cattle) Sus scrofa (pig) Equus caballus (horse) Oryctolagus cuniculus (rabbit) Canis lupus familiaris (dog) Felis catus (cat) Cavia porcellus (guinea pig) Erinaceus europaeus (hedgehog) Gallus gallus (chicken) Anolis carolinensis (green anole) Xenopus tropicalis (western clawed frog)	17 genes ENSG00000012779 ALOX5 ENSMUSG00000025701 Alox5 ENSPTRG00000002458 ALOX5 ENSGGOG00000012775 ALOX5 ENSMMUG00000013434 ALOX5 ENSRNOG00000012972 Alox5 ENSBTAG00000020319 ALOX5 ENSSSCG00000010404 ALOX5 ENSECAG00000012930 ALOX5 ENSOCUG00000005428 ALOX5 ENSCAFG00000006948 ALOX5 ENSFCAG00000013124 ALOX5 ENSCPOG00000003939 ALOX5 ENSEEUG00000006465 ALOX5 ENSGALG00000005857 ALOX5 ENSACAG00000013726 ALOX5 ENSXETG00000007490 alox5	Compare expression	[+]

Orthology information comes from OMA : ENSDARG00000057273.

Paralogs (same species)

Taxon name	Gene(s)	Expression comparison	See details
Chordata	6 genes ENSDARG00000016789 zgc:152891 ENSDARG00000043085 alox5b.1 ENSDARG00000043089 alox5b.2 ENSDARG00000069463 alox12 ENSDARG00000069966 alox5b.3 ENSDARG00000073781 si:dkey-17e16.9	Compare expression	[+]

Paralogy information comes from OMA : ENSDARG00000057273.

Cross-references

Ensembl	ENSDARG00000057273 (alox5a)
ZFIN	ZDB-GENE-090311-47 (alox5a)
EMBL	BX927098, CU012047
Uniprot/SPTREMBL	B8A697, B8A697_DANRE