Gene: cxcr4a - ENSDARG00000057633 - Danio rerio (zebrafish)

General information

Ensembl ID	ENSDARG00000057633
Name	cxcr4a
Description	chemokine (C-X-C motif) receptor 4a [Source:ZFIN;Acc:ZDB-GENE-020102-1]
Organism	Danio rerio (zebrafish)
Synonym(s)	cb824
Orthologs(s)	16 orthologs
Paralog(s)	1 paralogs

Expression

Anat. entity ID	Anatomical entity	Developmental stage(s)	Rank score	Expression score	Sources
UBERON:0004734	gastrula	[+] 6 stages ZFS:0000019Gastrula:Shield ZFS:0000017Gastrula:50%-epiboly ZFS:0000022Gastrula:Bud ZFS:0000021Gastrula:90%-epiboly UBERON:0000109gastrula stage ZFS:0000020Gastrula:75%-epiboly	664 664 1.88e3 2.00e3 2.30e3 2.67e3 2.75e3	97.78 97.78 93.71 93.32 92.31 91.05 90.80	AEIR AEIR AEIR AEIR AEIR AEIR AEIR
UBERON:0000307	blastula	[+] 4 stages ZFS:0000015Blastula:Dome ZFS:0000016Blastula:30%-epiboly ZFS:0000014Blastula:Sphere ZFS:0000011Blastula:1k-cell	750 750 832 1.03e4 1.22e4	97.49 97.49 97.22 65.46 59.11	AEIR AEIR AEIR AEIR AEIR
UBERON:0000468	multi-cellular organism	[+] 16 stages ZFS:0000019Gastrula:Shield ZFS:0000020Gastrula:75%-epiboly ZFS:0000022Gastrula:Bud ZFS:0000021Gastrula:90%-epiboly ZFS:0000024Segmentation:5-9 somites ZFS:0000026Segmentation:14-19 somites ZFS:0000029Pharyngula:Prim-5 ZFS:0000030Pharyngula:Prim-15 UBERON:0000068embryo stage ZFS:0000033Hatching:Long-pec UBERON:0000106zygote stage ZFS:0000042Juvenile:Days 30-44 ZFS:0000036Larval:Day 4 ZFS:0000037Larval:Day 5 UBERON:0000066fully formed stage UBERON:0000109gastrula stage	928 928 2.15e3 2.43e3 2.47e3 3.84e3 7.30e3 9.30e3 9.73e3 1.09e4 1.15e4 1.26e4 1.41e4 1.41e4 1.43e4 1.49e4 1.49e4	96.90 96.90 92.79 91.86 91.74 87.13 75.57 68.85 67.43 63.56 61.65 57.88 52.70 52.67 52.08 50.25 49.99	AEIR AEIR AEIR AEIR AEIR AEIR AEIR AEIR AEIR AEIR AEIR AEIR AEIR AEIR AEIR AEIR AEIR
CL:0000094	granulocyte	[+] 1 stage UBERON:0000066fully formed stage	929 929	96.89 96.89	AEIR AEIR
UBERON:0000206	pharyngeal gill	[+] 1 stage UBERON:0000066fully formed stage	2.09e3 2.09e3	93.02 93.02	AEIR AEIR
UBERON:4000164	caudal fin	[+] 2 stages UBERON:0000066fully formed stage ZFS:0000033Hatching:Long-pec	3.54e3 3.54e3 4.17e3	88.15 88.15 86.04	AEIR AEIR AEIR
UBERON:0009620	tail bud paraxial mesoderm	[+] 1 stage ZFS:0000027Segmentation:20-25 somites	3.77e3 3.77e3	87.39 87.39	AEIR AEIR
UBERON:0001637	artery	[+] 7 stages ZFS:0000027Segmentation:20-25 somites ZFS:0000028Segmentation:26+ somites ZFS:0000029Pharyngula:Prim-5 ZFS:0000032Pharyngula:High-pec ZFS:0000033Hatching:Long-pec ZFS:0000030Pharyngula:Prim-15 ZFS:0000031Pharyngula:Prim-25	4.98e3 4.98e3 4.98e3 5.75e3 8.96e3 8.96e3 9.51e3 9.51e3	83.33 83.33 83.33 80.76 69.99 69.99 68.17 68.17	AEIR AEIR AEIR AEIR AEIR AEIR AEIR AEIR
UBERON:0000922	embryo	[+] 10 stages ZFS:0000029Pharyngula:Prim-5 UBERON:0004707pharyngula stage ZFS:0000024Segmentation:5-9 somites UBERON:0000068embryo stage ZFS:0000026Segmentation:14-19 somites ZFS:0000025Segmentation:10-13 somites ZFS:0000030Pharyngula:Prim-15 ZFS:0000031Pharyngula:Prim-25 ZFS:0000033Hatching:Long-pec ZFS:0000037Larval:Day 5	5.43e3 5.43e3 5.97e3 6.42e3 7.36e3 7.66e3 7.92e3 8.86e3 1.35e4 1.53e4 1.88e4	81.82 81.82 80.00 78.51 75.36 74.35 73.49 70.33 54.81 48.79 37.05	AEIR AEIR AEIR AEIR AEIR AEIR AEIR AEIR AEIR AEIR AEIR
UBERON:0002329	somite	[+] 10 stages ZFS:0000025Segmentation:10-13 somites ZFS:0000026Segmentation:14-19 somites ZFS:0000032Pharyngula:High-pec ZFS:0000024Segmentation:5-9 somites ZFS:0000023Segmentation:1-4 somites ZFS:0000030Pharyngula:Prim-15 ZFS:0000031Pharyngula:Prim-25 ZFS:0000027Segmentation:20-25 somites ZFS:0000029Pharyngula:Prim-5 ZFS:0000033Hatching:Long-pec	5.50e3 5.50e3 6.70e3 7.47e3 7.47e3 8.83e3 1.12e4 1.19e4 1.20e4 1.25e4 1.31e4	81.59 81.59 77.57 75.00 74.98 70.44 62.50 60.00 59.98 58.30 56.24	AEIR AEIR AEIR AEIR AEIR AEIR AEIR AEIR AEIR AEIR AEIR
UBERON:0001638	vein	[+] 7 stages ZFS:0000027Segmentation:20-25 somites ZFS:0000028Segmentation:26+ somites ZFS:0000029Pharyngula:Prim-5 ZFS:0000032Pharyngula:High-pec ZFS:0000033Hatching:Long-pec ZFS:0000030Pharyngula:Prim-15 ZFS:0000031Pharyngula:Prim-25	5.75e3 5.75e3 5.75e3 6.97e3 7.47e3 7.47e3 9.34e3 9.34e3	80.76 80.76 80.76 76.66 74.99 74.99 68.74 68.74	AEIR AEIR AEIR AEIR AEIR AEIR AEIR AEIR
UBERON:2000001	Kupffer's vesicle	[+] 3 stages ZFS:0000024Segmentation:5-9 somites ZFS:0000023Segmentation:1-4 somites ZFS:0000025Segmentation:10-13 somites	5.75e3 5.75e3 6.22e3 6.89e3	80.76 80.76 79.16 76.92	AEIR AEIR AEIR AEIR
UBERON:2000083	ventral mesoderm	[+] 4 stages ZFS:0000026Segmentation:14-19 somites ZFS:0000023Segmentation:1-4 somites ZFS:0000024Segmentation:5-9 somites ZFS:0000025Segmentation:10-13 somites	6.15e3 6.15e3 7.97e3 7.97e3 8.54e3	79.40 79.40 73.32 73.32 71.42	AEIR AEIR AEIR AEIR AEIR
UBERON:0003058	hypochord	[+] 3 stages ZFS:0000029Pharyngula:Prim-5 ZFS:0000028Segmentation:26+ somites ZFS:0000027Segmentation:20-25 somites	6.40e3 6.40e3 6.89e3 7.47e3	78.56 78.56 76.92 74.99	AEIR AEIR AEIR AEIR
ZFA:0000023	forerunner cell group (Danio)	[+] 6 stages ZFS:0000022Gastrula:Bud ZFS:0000020Gastrula:75%-epiboly ZFS:0000017Gastrula:50%-epiboly ZFS:0000018Gastrula:Germ-ring ZFS:0000019Gastrula:Shield ZFS:0000021Gastrula:90%-epiboly	6.40e3 6.40e3 6.54e3 6.79e3 6.79e3 6.89e3 6.89e3	78.56 78.56 78.12 77.27 77.27 76.92 76.92	AEIR AEIR AEIR AEIR AEIR AEIR AEIR
UBERON:0003059	presomitic mesoderm	[+] 1 stage ZFS:0000025Segmentation:10-13 somites	6.42e3 6.42e3	78.50 78.50	AEIR AEIR
UBERON:0000926	mesoderm	[+] 7 stages ZFS:0000026Segmentation:14-19 somites ZFS:0000017Gastrula:50%-epiboly ZFS:0000018Gastrula:Germ-ring ZFS:0000019Gastrula:Shield ZFS:0000021Gastrula:90%-epiboly ZFS:0000022Gastrula:Bud ZFS:0000020Gastrula:75%-epiboly	6.54e3 6.54e3 1.03e4 1.03e4 1.03e4 1.03e4 1.03e4 1.07e4	78.12 78.12 65.37 65.37 65.37 65.37 65.37 64.27	AEIR AEIR AEIR AEIR AEIR AEIR AEIR AEIR
UBERON:0003055	periderm	[+] 7 stages ZFS:0000023Segmentation:1-4 somites ZFS:0000024Segmentation:5-9 somites ZFS:0000025Segmentation:10-13 somites ZFS:0000027Segmentation:20-25 somites ZFS:0000026Segmentation:14-19 somites ZFS:0000028Segmentation:26+ somites ZFS:0000029Pharyngula:Prim-5	6.54e3 6.54e3 6.97e3 6.97e3 7.03e3 7.47e3 7.97e3 7.97e3	78.12 78.12 76.66 76.66 76.46 74.99 73.32 73.32	AEIR AEIR AEIR AEIR AEIR AEIR AEIR AEIR
UBERON:0001049	neural tube	[+] 1 stage ZFS:0000026Segmentation:14-19 somites	6.72e3 6.72e3	77.49 77.49	AEIR AEIR
UBERON:0000014	zone of skin	[+] 1 stage UBERON:0000066fully formed stage	7.15e3 7.15e3	76.07 76.07	AEIR AEIR
UBERON:0001633	basilar artery	[+] 1 stage ZFS:0000030Pharyngula:Prim-15	7.47e3 7.47e3	75.00 75.00	AEIR AEIR
UBERON:0011362	cranial blood vasculature	[+] 1 stage ZFS:0000031Pharyngula:Prim-25	7.47e3 7.47e3	75.00 75.00	AEIR AEIR
UBERON:2001052	primordial hindbrain channel	[+] 1 stage ZFS:0000030Pharyngula:Prim-15	7.47e3 7.47e3	75.00 75.00	AEIR AEIR
UBERON:2005020	central artery	[+] 1 stage ZFS:0000033Hatching:Long-pec	7.47e3 7.47e3	75.00 75.00	AEIR AEIR
UBERON:0002100	trunk	[+] 1 stage ZFS:0000033Hatching:Long-pec	7.47e3 7.47e3	75.00 75.00	AEIR AEIR
UBERON:0003071	eye primordium	[+] 4 stages ZFS:0000022Gastrula:Bud ZFS:0000023Segmentation:1-4 somites ZFS:0000024Segmentation:5-9 somites ZFS:0000025Segmentation:10-13 somites	7.47e3 7.47e3 8.54e3 9.19e3 9.19e3	75.00 75.00 71.42 69.22 69.22	AEIR AEIR AEIR AEIR AEIR
UBERON:0000925	endoderm	[+] 7 stages ZFS:0000019Gastrula:Shield ZFS:0000022Gastrula:Bud ZFS:0000020Gastrula:75%-epiboly ZFS:0000017Gastrula:50%-epiboly ZFS:0000018Gastrula:Germ-ring ZFS:0000021Gastrula:90%-epiboly ZFS:0000025Segmentation:10-13 somites	7.47e3 7.47e3 7.47e3 7.47e3 8.30e3 8.30e3 8.30e3 1.31e4	75.00 75.00 75.00 74.99 72.22 72.22 72.22 56.24	AEIR AEIR AEIR AEIR AEIR AEIR AEIR AEIR
UBERON:0004128	optic vesicle	[+] 3 stages ZFS:0000024Segmentation:5-9 somites ZFS:0000025Segmentation:10-13 somites ZFS:0000023Segmentation:1-4 somites	7.47e3 7.47e3 8.40e3 9.19e3	74.99 74.99 71.86 69.22	AEIR AEIR AEIR AEIR
UBERON:0001003	skin epidermis	[+] 5 stages ZFS:0000027Segmentation:20-25 somites ZFS:0000028Segmentation:26+ somites ZFS:0000029Pharyngula:Prim-5 ZFS:0000030Pharyngula:Prim-15 ZFS:0000031Pharyngula:Prim-25	8.22e3 8.22e3 8.22e3 8.54e3 8.79e3 9.34e3	72.48 72.48 72.48 71.41 70.57 68.74	AEIR AEIR AEIR AEIR AEIR AEIR
UBERON:0005886	post-hyoid pharyngeal arch skeleton	[+] 7 stages ZFS:0000027Segmentation:20-25 somites ZFS:0000028Segmentation:26+ somites ZFS:0000029Pharyngula:Prim-5 ZFS:0000030Pharyngula:Prim-15 ZFS:0000031Pharyngula:Prim-25 ZFS:0000032Pharyngula:High-pec ZFS:0000033Hatching:Long-pec	8.96e3 8.96e3 8.96e3 9.25e3 9.44e3 9.44e3 9.67e3 9.67e3	69.98 69.98 69.98 69.03 68.40 68.40 67.63 67.63	AEIR AEIR AEIR AEIR AEIR AEIR AEIR AEIR
UBERON:0004879	marginal zone of embryo	[+] 6 stages ZFS:0000020Gastrula:75%-epiboly ZFS:0000019Gastrula:Shield ZFS:0000021Gastrula:90%-epiboly ZFS:0000018Gastrula:Germ-ring ZFS:0000022Gastrula:Bud ZFS:0000017Gastrula:50%-epiboly	9.44e3 9.44e3 1.02e4 1.07e4 1.10e4 1.10e4 1.12e4	68.40 68.40 65.77 64.27 63.32 63.32 62.48	AEIR AEIR AEIR AEIR AEIR AEIR AEIR
UBERON:0000033	head	[+] 7 stages ZFS:0000027Segmentation:20-25 somites ZFS:0000026Segmentation:14-19 somites ZFS:0000033Hatching:Long-pec ZFS:0000035Larval:Protruding-mouth UBERON:0000066fully formed stage ZFS:0000032Pharyngula:High-pec ZFS:0000037Larval:Day 5	9.96e3 9.96e3 1.12e4 1.12e4 1.12e4 1.37e4 1.49e4 1.77e4	66.67 66.67 62.50 62.50 62.50 54.00 50.00 40.75	AEIR AEIR AEIR AEIR AEIR AEIR AEIR AEIR
UBERON:2001054	lateral dorsal aorta	[+] 3 stages ZFS:0000029Pharyngula:Prim-5 ZFS:0000030Pharyngula:Prim-15 ZFS:0000031Pharyngula:Prim-25	9.96e3 9.96e3 1.49e4 1.49e4	66.67 66.67 50.00 50.00	AEIR AEIR AEIR AEIR
UBERON:0007132	head kidney	[+] 1 stage UBERON:0000066fully formed stage	1.04e4 1.04e4	65.07 65.07	AEIR AEIR
UBERON:0019248	early embryo	[+] 1 stage UBERON:0000107cleavage stage	1.05e4 1.05e4	64.91 64.91	AEIR AEIR
UBERON:0000992	female gonad	[+] 2 stages UBERON:0000066fully formed stage UBERON:0000104life cycle	1.11e4 1.11e4 1.50e4	62.81 62.81 49.89	AEIR AEIR AEIR
UBERON:0000955	brain	[+] 6 stages ZFS:0000031Pharyngula:Prim-25 ZFS:0000033Hatching:Long-pec ZFS:0000032Pharyngula:High-pec ZFS:0000029Pharyngula:Prim-5 ZFS:0000030Pharyngula:Prim-15 UBERON:0000066fully formed stage	1.11e4 1.11e4 1.22e4 1.31e4 1.34e4 1.49e4 1.67e4	62.76 62.76 59.08 56.24 54.99 49.99 44.21	AEIR AEIR AEIR AEIR AEIR AEIR AEIR
UBERON:0000970	eye	[+] 1 stage ZFS:0000031Pharyngula:Prim-25	1.18e4 1.18e4	60.59 60.59	AEIR AEIR
UBERON:0003982	mature ovarian follicle	[+] 1 stage UBERON:0000066fully formed stage	1.19e4 1.19e4	60.26 60.26	AEIR AEIR
UBERON:0002200	vasculature of head	[+] 2 stages ZFS:0000029Pharyngula:Prim-5 ZFS:0000031Pharyngula:Prim-25	1.19e4 1.19e4 1.49e4	60.00 60.00 50.00	AEIR AEIR AEIR
UBERON:0003062	primitive knot	[+] 1 stage ZFS:0000019Gastrula:Shield	1.22e4 1.22e4	59.08 59.08	AEIR AEIR
UBERON:0003063	prechordal plate	[+] 1 stage ZFS:0000022Gastrula:Bud	1.28e4 1.28e4	57.14 57.14	AEIR AEIR
UBERON:0002548	larva	[+] 3 stages UBERON:0000069larval stage ZFS:0000037Larval:Day 5 ZFS:0000035Larval:Protruding-mouth	1.31e4 1.31e4 1.40e4 1.53e4	56.05 56.05 52.97 48.78	AEIR AEIR AEIR AEIR
UBERON:0001630	muscle organ	[+] 1 stage UBERON:0000066fully formed stage	1.34e4 1.34e4	55.19 55.19	AEIR AEIR
UBERON:2001157	posterior lateral line primordium	[+] 1 stage ZFS:0000030Pharyngula:Prim-15	1.36e4 1.36e4	54.53 54.53	AEIR AEIR
UBERON:2000040	median fin fold	[+] 1 stage ZFS:0000029Pharyngula:Prim-5	1.38e4 1.38e4	53.83 53.83	AEIR AEIR
UBERON:0005805	dorsal aorta	[+] 1 stage ZFS:0000029Pharyngula:Prim-5	1.39e4 1.39e4	53.55 53.55	AEIR AEIR
UBERON:0002106	spleen	[+] 1 stage UBERON:0000066fully formed stage	1.44e4 1.44e4	51.64 51.64	AEIR AEIR
CL:0000099	interneuron	[+] 1 stage ZFS:0000025Segmentation:10-13 somites	1.49e4 1.49e4	50.00 50.00	AEIR AEIR
CL:0000704	endothelial tip cell	[+] 1 stage ZFS:0000031Pharyngula:Prim-25	1.49e4 1.49e4	50.00 50.00	AEIR AEIR
UBERON:0003089	sclerotome	[+] 1 stage ZFS:0000025Segmentation:10-13 somites	1.49e4 1.49e4	50.00 50.00	AEIR AEIR
UBERON:0005396	carotid artery segment	[+] 1 stage ZFS:0000029Pharyngula:Prim-5	1.49e4 1.49e4	50.00 50.00	AEIR AEIR
UBERON:0014903	primordial vasculature	[+] 2 stages ZFS:0000027Segmentation:20-25 somites ZFS:0000026Segmentation:14-19 somites	1.49e4 1.49e4 1.49e4	50.00 50.00 50.00	AEIR AEIR AEIR
UBERON:2005000	basal communicating artery	[+] 1 stage ZFS:0000031Pharyngula:Prim-25	1.49e4 1.49e4	50.00 50.00	AEIR AEIR
UBERON:0003056	pre-chordal neural plate	[+] 2 stages ZFS:0000020Gastrula:75%-epiboly ZFS:0000021Gastrula:90%-epiboly	1.49e4 1.49e4 1.49e4	50.00 50.00 50.00	AEIR AEIR AEIR
UBERON:2007026	forebrain neural keel	[+] 1 stage ZFS:0000022Gastrula:Bud	1.49e4 1.49e4	50.00 50.00	AEIR AEIR
ZFA:0000003	adaxial cell (Danio)	[+] 1 stage ZFS:0000022Gastrula:Bud	1.49e4 1.49e4	49.99 49.99	AEIR AEIR
UBERON:0006595	presumptive endoderm	[+] 1 stage ZFS:0000019Gastrula:Shield	1.49e4 1.49e4	49.99 49.99	AEIR AEIR
ZFA:0001065	lateral mesoderm (Danio)	[+] 1 stage ZFS:0000025Segmentation:10-13 somites	1.49e4 1.49e4	49.99 49.99	AEIR AEIR
UBERON:0000019	camera-type eye	[+] 1 stage UBERON:0000066fully formed stage	1.50e4 1.50e4	49.94 49.94	AEIR AEIR
UBERON:0002481	bone tissue	[+] 1 stage UBERON:0000066fully formed stage	1.51e4 1.51e4	49.28 49.28	AEIR AEIR
UBERON:0002385	muscle tissue	[+] 1 stage UBERON:0000066fully formed stage	1.53e4 1.53e4	48.61 48.61	AEIR AEIR
UBERON:0000160	intestine	[+] 1 stage UBERON:0000066fully formed stage	1.62e4 1.62e4	45.81 45.81	AEIR AEIR
UBERON:0006860	swim bladder	[+] 1 stage UBERON:0000066fully formed stage	1.64e4 1.64e4	45.00 45.00	AEIR AEIR
UBERON:0000948	heart	[+] 2 stages UBERON:0000066fully formed stage ZFS:0000036Larval:Day 4	1.66e4 1.66e4 1.76e4	44.29 44.29 40.96	AEIR AEIR AEIR
UBERON:0002107	liver	[+] 1 stage UBERON:0000066fully formed stage	1.74e4 1.74e4	41.78 41.78	AEIR AEIR

Sources
A	Affymetrix
E	EST
I	In Situ
R	RNA-Seq

data

no data

Rank scores
3.25e4	lightgrey: low confidence scores
	important score variation

Rank scores of expression calls are normalized across genes, conditions and species. Low score means that the gene is highly expressed in the condition. Max rank score in all species: 4.10e4. Min rank score varies across species.

Expression scores of expression calls use the minimum and maximum Rank of the species to normalize the expression to a value between 0 and 100. Low score means that the gene is lowly expressed in the condition.

Sources of annotations to anatomy and development:

Affymetrix data: Bgee
EST data: Bgee
In situ hybridization data: ZFIN
RNA-Seq data: Bgee

Sources of raw data:

Affymetrix data: ArrayExpress, GEO
EST data: UniGene
In situ hybridization data: ZFIN
RNA-Seq data: GEO

Orthologs

Taxon name	Species with orthologs	Gene(s)	Expression comparison	See details
Euteleostomi	16 species Homo sapiens (human) Mus musculus (mouse) Pan troglodytes (chimpanzee) Gorilla gorilla (gorilla) Macaca mulatta (macaque) Rattus norvegicus (rat) Bos taurus (cattle) Equus caballus (horse) Oryctolagus cuniculus (rabbit) Canis lupus familiaris (dog) Felis catus (cat) Monodelphis domestica (opossum) Ornithorhynchus anatinus (platypus) Gallus gallus (chicken) Anolis carolinensis (green anole) Xenopus tropicalis (western clawed frog)	16 genes ENSG00000121966 CXCR4 ENSMUSG00000045382 Cxcr4 ENSPTRG00000012501 CXCR4 ENSGGOG00000016862 CXCR4 ENSMMUG00000011918 CXCR4 ENSRNOG00000003866 Cxcr4 ENSBTAG00000001060 CXCR4 ENSECAG00000003837 CXCR4 ENSOCUG00000001923 CXCR4 ENSCAFG00000005109 CXCR4 ENSFCAG00000015575 CXCR4 ENSMODG00000001101 CXCR4 ENSOANG00000007993 CXCR4 ENSGALG00000012357 CXCR4 ENSACAG00000000795 CXCR4 ENSXETG00000014890 cxcr4	Compare expression	[+]

Orthology information comes from OMA : ENSDARG00000057633.

Paralogs (same species)

Taxon name	Gene(s)	Expression comparison	See details
Clupeocephala	1 gene ENSDARG00000041959 cxcr4b	Compare expression	[+]

Paralogy information comes from OMA : ENSDARG00000057633.

Cross-references

Ensembl	ENSDARG00000057633 (cxcr4a)
ZFIN	ZDB-GENE-020102-1 (cxcr4a)
EMBL	CU639412
Uniprot/SPTREMBL	F1QCB2, F1QCB2_DANRE, F8W4X7, F8W4X7_DANRE