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D. rerio Gene: topbp1 - ENSDARG00000059322 - Danio rerio (zebrafish)

General information

Ensembl IDENSDARG00000059322
Nametopbp1
Descriptiontopoisomerase (DNA) II binding protein 1 [Source:ZFIN;Acc:ZDB-GENE-060626-1]
OrganismDanio rerio (zebrafish)
Orthologs(s)24 orthologs

Expression

Anat. entity IDAnatomical entityDevelopmental stage(s)Rank scoreExpression scoreSources
UBERON:0000061anatomical structure
  • ZFS:0000033Hatching:Long-pec
  • ZFS:0000026Segmentation:14-19 somites
  • ZFS:0000028Segmentation:26+ somites
  • ZFS:0000031Pharyngula:Prim-25
  • ZFS:0000035Larval:Protruding-mouth
  • ZFS:0000036Larval:Day 4
  • ZFS:0000037Larval:Day 5
878
  • 878
  • 7.47e3
  • 1.49e4
  • 1.49e4
  • 1.49e4
  • 1.49e4
  • 1.49e4
97.06
  • 97.06
  • 75.00
  • 50.00
  • 50.00
  • 50.00
  • 50.00
  • 50.00
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0003982mature ovarian follicle
  • UBERON:0000066fully formed stage
3.38e3
  • 3.38e3
88.68
  • 88.68
AEIR
  • AEIR
UBERON:0019248early embryo
  • UBERON:0000107cleavage stage
4.77e3
  • 4.77e3
84.02
  • 84.02
AEIR
  • AEIR
UBERON:0000468multi-cellular organism
  • UBERON:0000106zygote stage
  • ZFS:0000025Segmentation:10-13 somites
  • ZFS:0000020Gastrula:75%-epiboly
  • ZFS:0000022Gastrula:Bud
  • ZFS:0000021Gastrula:90%-epiboly
  • ZFS:0000024Segmentation:5-9 somites
  • ZFS:0000026Segmentation:14-19 somites
  • ZFS:0000029Pharyngula:Prim-5
  • ZFS:0000019Gastrula:Shield
  • ZFS:0000030Pharyngula:Prim-15
  • ZFS:0000014Blastula:Sphere
  • ZFS:0000033Hatching:Long-pec
  • ZFS:0000042Juvenile:Days 30-44
  • ZFS:0000040Larval:Days 14-20
  • ZFS:0000036Larval:Day 4
  • ZFS:0000037Larval:Day 5
  • UBERON:0000104life cycle
  • UBERON:0000066fully formed stage
5.10e3
  • 5.10e3
  • 6.54e3
  • 6.92e3
  • 7.23e3
  • 7.38e3
  • 8.07e3
  • 8.08e3
  • 8.31e3
  • 8.36e3
  • 8.43e3
  • 8.96e3
  • 9.09e3
  • 9.88e3
  • 9.89e3
  • 1.05e4
  • 1.07e4
  • 1.50e4
  • 1.50e4
82.93
  • 82.93
  • 78.12
  • 76.82
  • 75.81
  • 75.29
  • 72.97
  • 72.96
  • 72.19
  • 72.00
  • 71.77
  • 69.99
  • 69.55
  • 66.91
  • 66.90
  • 64.76
  • 64.28
  • 49.92
  • 49.81
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0002415tail
  • UBERON:0000066fully formed stage
5.45e3
  • 5.45e3
81.76
  • 81.76
AEIR
  • AEIR
UBERON:0000307blastula
  • ZFS:0000011Blastula:1k-cell
  • ZFS:0000014Blastula:Sphere
  • ZFS:0000009Blastula:256-cell
  • ZFS:0000016Blastula:30%-epiboly
  • ZFS:0000015Blastula:Dome
5.64e3
  • 5.64e3
  • 7.28e3
  • 7.45e3
  • 7.91e3
  • 8.23e3
81.12
  • 81.12
  • 75.63
  • 75.07
  • 73.53
  • 72.46
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0004734gastrula
  • ZFS:0000022Gastrula:Bud
  • UBERON:0000109gastrula stage
  • ZFS:0000020Gastrula:75%-epiboly
  • ZFS:0000019Gastrula:Shield
  • ZFS:0000017Gastrula:50%-epiboly
  • ZFS:0000021Gastrula:90%-epiboly
5.75e3
  • 5.75e3
  • 6.84e3
  • 6.96e3
  • 7.20e3
  • 8.17e3
  • 8.79e3
80.75
  • 80.75
  • 77.10
  • 76.70
  • 75.88
  • 72.64
  • 70.57
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0003077paraxial mesoderm
  • ZFS:0000025Segmentation:10-13 somites
6.28e3
  • 6.28e3
78.96
  • 78.96
AEIR
  • AEIR
UBERON:0000473testis
  • UBERON:0000066fully formed stage
6.49e3
  • 6.49e3
78.28
  • 78.28
AEIR
  • AEIR
UBERON:0000966retina
  • ZFS:0000031Pharyngula:Prim-25
  • UBERON:0000066fully formed stage
  • ZFS:0000033Hatching:Long-pec
6.54e3
  • 6.54e3
  • 8.44e3
  • 9.06e3
78.09
  • 78.09
  • 71.73
  • 69.68
AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0002329somite
  • ZFS:0000025Segmentation:10-13 somites
6.78e3
  • 6.78e3
77.30
  • 77.30
AEIR
  • AEIR
UBERON:4000164caudal fin
  • ZFS:0000035Larval:Protruding-mouth
  • ZFS:0000033Hatching:Long-pec
  • UBERON:0000066fully formed stage
7.47e3
  • 7.47e3
  • 1.14e4
  • 1.15e4
75.00
  • 75.00
  • 61.96
  • 61.59
AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0000922embryo
  • ZFS:0000024Segmentation:5-9 somites
  • UBERON:0004707pharyngula stage
  • UBERON:0000068embryo stage
  • ZFS:0000026Segmentation:14-19 somites
  • ZFS:0000025Segmentation:10-13 somites
  • ZFS:0000029Pharyngula:Prim-5
  • ZFS:0000031Pharyngula:Prim-25
  • ZFS:0000030Pharyngula:Prim-15
  • ZFS:0000033Hatching:Long-pec
  • ZFS:0000037Larval:Day 5
7.56e3
  • 7.56e3
  • 8.39e3
  • 8.50e3
  • 9.13e3
  • 9.21e3
  • 9.32e3
  • 9.94e3
  • 1.07e4
  • 1.27e4
  • 1.59e4
74.70
  • 74.70
  • 71.92
  • 71.54
  • 69.45
  • 69.17
  • 68.78
  • 66.70
  • 64.04
  • 57.62
  • 46.63
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0002113kidney
  • UBERON:0000066fully formed stage
7.60e3
  • 7.60e3
74.57
  • 74.57
AEIR
  • AEIR
UBERON:0003059presomitic mesoderm
  • ZFS:0000025Segmentation:10-13 somites
7.85e3
  • 7.85e3
73.72
  • 73.72
AEIR
  • AEIR
UBERON:0007010cleaving embryo
  • ZFS:0000005Cleavage:16-cell
8.03e3
  • 8.03e3
73.11
  • 73.11
AEIR
  • AEIR
CL:0000094granulocyte
  • UBERON:0000066fully formed stage
8.72e3
  • 8.72e3
70.81
  • 70.81
AEIR
  • AEIR
UBERON:0000948heart
  • ZFS:0000036Larval:Day 4
  • UBERON:0000066fully formed stage
9.28e3
  • 9.28e3
  • 1.44e4
68.93
  • 68.93
  • 51.79
AEIR
  • AEIR
  • AEIR
UBERON:0009620tail bud paraxial mesoderm
  • ZFS:0000027Segmentation:20-25 somites
9.74e3
  • 9.74e3
67.37
  • 67.37
AEIR
  • AEIR
UBERON:0002199integument
  • UBERON:0000066fully formed stage
1.03e4
  • 1.03e4
65.47
  • 65.47
AEIR
  • AEIR
UBERON:0002385muscle tissue
  • UBERON:0000066fully formed stage
1.03e4
  • 1.03e4
65.45
  • 65.45
AEIR
  • AEIR
UBERON:0002481bone tissue
  • UBERON:0000066fully formed stage
1.10e4
  • 1.10e4
63.21
  • 63.21
AEIR
  • AEIR
UBERON:0000033head
  • ZFS:0000035Larval:Protruding-mouth
  • ZFS:0000037Larval:Day 5
  • UBERON:0000066fully formed stage
1.12e4
  • 1.12e4
  • 1.38e4
  • 1.85e4
62.50
  • 62.50
  • 53.96
  • 38.20
AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0000955brain
  • ZFS:0000031Pharyngula:Prim-25
  • UBERON:0000066fully formed stage
1.17e4
  • 1.17e4
  • 1.42e4
60.69
  • 60.69
  • 52.47
AEIR
  • AEIR
  • AEIR
UBERON:0007132head kidney
  • UBERON:0000066fully formed stage
1.29e4
  • 1.29e4
56.94
  • 56.94
AEIR
  • AEIR
UBERON:0002548larva
  • UBERON:0000069larval stage
  • ZFS:0000035Larval:Protruding-mouth
  • ZFS:0000037Larval:Day 5
1.30e4
  • 1.30e4
  • 1.42e4
  • 1.55e4
56.51
  • 56.51
  • 52.56
  • 48.22
AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0002106spleen
  • UBERON:0000066fully formed stage
1.31e4
  • 1.31e4
55.97
  • 55.97
AEIR
  • AEIR
UBERON:0002107liver
  • UBERON:0000066fully formed stage
1.32e4
  • 1.32e4
55.82
  • 55.82
AEIR
  • AEIR
UBERON:0000160intestine
  • UBERON:0000066fully formed stage
1.36e4
  • 1.36e4
54.51
  • 54.51
AEIR
  • AEIR
UBERON:0001630muscle organ
  • UBERON:0000066fully formed stage
1.41e4
  • 1.41e4
52.93
  • 52.93
AEIR
  • AEIR
UBERON:0000014zone of skin
  • UBERON:0000066fully formed stage
1.44e4
  • 1.44e4
51.69
  • 51.69
AEIR
  • AEIR
UBERON:0000206pharyngeal gill
  • UBERON:0000066fully formed stage
1.50e4
  • 1.50e4
49.85
  • 49.85
AEIR
  • AEIR
UBERON:0006860swim bladder
  • UBERON:0000066fully formed stage
1.73e4
  • 1.73e4
42.19
  • 42.19
AEIR
  • AEIR
Sources
AAffymetrix
EEST
IIn Situ
RRNA-Seq
data
no data
Rank scores
3.25e4lightgrey: low confidence scores

important score variation

Rank scores of expression calls are normalized across genes, conditions and species. Low score means that the gene is highly expressed in the condition. Max rank score in all species: 4.10e4. Min rank score varies across species.

Expression scores of expression calls use the minimum and maximum Rank of the species to normalize the expression to a value between 0 and 100. Low score means that the gene is lowly expressed in the condition.

Sources of annotations to anatomy and development:
  • Affymetrix data: Bgee
  • EST data: Bgee
  • In situ hybridization data: ZFIN
  • RNA-Seq data: Bgee
Sources of raw data:

Orthologs

Taxon nameSpecies with orthologsGene(s)Expression comparisonSee details
Euteleostomi19 species19 genesCompare expression
Bilateria24 species24 genesCompare expression

Orthology information comes from OMA : ENSDARG00000059322.

Cross-references

EnsemblENSDARG00000059322 (topbp1)
ZFINZDB-GENE-060626-1 (topbp1)
EMBLBX649325
Uniprot/SPTREMBLF1QTB3, F1QTB3_DANRE, F1R135, F1R135_DANRE

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