Gene: klhl2 - ENSDARG00000061786 - Danio rerio (zebrafish)

General information

Ensembl ID	ENSDARG00000061786
Name	klhl2
Description	kelch-like family member 2 [Source:ZFIN;Acc:ZDB-GENE-090312-193]
Organism	Danio rerio (zebrafish)
Synonym(s)	si:ch211-287c11.1
Orthologs(s)	19 orthologs
Paralog(s)	10 paralogs

Expression

Anat. entity ID	Anatomical entity	Developmental stage(s)	Rank score	Expression score	Sources
UBERON:0003982	mature ovarian follicle	[+] 1 stage UBERON:0000066fully formed stage	1.37e3 1.37e3	95.41 95.41	AEIR AEIR
UBERON:0019248	early embryo	[+] 1 stage UBERON:0000107cleavage stage	2.59e3 2.59e3	91.34 91.34	AEIR AEIR
UBERON:0000473	testis	[+] 1 stage UBERON:0000066fully formed stage	5.63e3 5.63e3	81.16 81.16	AEIR AEIR
UBERON:0002415	tail	[+] 1 stage UBERON:0000066fully formed stage	6.62e3 6.62e3	77.83 77.83	AEIR AEIR
UBERON:0000955	brain	[+] 1 stage UBERON:0000066fully formed stage	7.92e3 7.92e3	73.49 73.49	AEIR AEIR
UBERON:0002113	kidney	[+] 1 stage UBERON:0000066fully formed stage	8.85e3 8.85e3	70.36 70.36	AEIR AEIR
UBERON:0004734	gastrula	[+] 2 stages ZFS:0000022Gastrula:Bud ZFS:0000019Gastrula:Shield	8.96e3 8.96e3 1.13e4	70.01 70.01 62.29	AEIR AEIR AEIR
UBERON:0000307	blastula	[+] 2 stages ZFS:0000011Blastula:1k-cell ZFS:0000015Blastula:Dome	9.08e3 9.08e3 1.15e4	69.61 69.61 61.54	AEIR AEIR AEIR
UBERON:0000922	embryo	[+] 5 stages ZFS:0000029Pharyngula:Prim-5 ZFS:0000033Hatching:Long-pec UBERON:0000068embryo stage UBERON:0004707pharyngula stage ZFS:0000037Larval:Day 5	9.52e3 9.52e3 1.01e4 1.06e4 1.11e4 1.17e4	68.11 68.11 66.17 64.60 62.74 60.79	AEIR AEIR AEIR AEIR AEIR AEIR
UBERON:0000966	retina	[+] 1 stage ZFS:0000037Larval:Day 5	9.56e3 9.56e3	68.00 68.00	AEIR AEIR
CL:0000094	granulocyte	[+] 1 stage UBERON:0000066fully formed stage	9.66e3 9.66e3	67.65 67.65	AEIR AEIR
UBERON:0002385	muscle tissue	[+] 1 stage UBERON:0000066fully formed stage	9.83e3 9.83e3	67.08 67.08	AEIR AEIR
UBERON:0002107	liver	[+] 1 stage UBERON:0000066fully formed stage	1.04e4 1.04e4	65.12 65.12	AEIR AEIR
UBERON:0000948	heart	[+] 2 stages ZFS:0000036Larval:Day 4 UBERON:0000066fully formed stage	1.04e4 1.04e4 1.17e4	65.02 65.02 60.95	AEIR AEIR AEIR
UBERON:0002548	larva	[+] 2 stages UBERON:0000069larval stage ZFS:0000037Larval:Day 5	1.16e4 1.16e4 1.25e4	61.26 61.26 58.25	AEIR AEIR AEIR
UBERON:0001630	muscle organ	[+] 1 stage UBERON:0000066fully formed stage	1.16e4 1.16e4	61.06 61.06	AEIR AEIR
UBERON:0002481	bone tissue	[+] 1 stage UBERON:0000066fully formed stage	1.16e4 1.16e4	61.04 61.04	AEIR AEIR
UBERON:0000970	eye	[+] 1 stage ZFS:0000031Pharyngula:Prim-25	1.18e4 1.18e4	60.62 60.62	AEIR AEIR
UBERON:0000160	intestine	[+] 1 stage UBERON:0000066fully formed stage	1.19e4 1.19e4	60.21 60.21	AEIR AEIR
UBERON:0000033	head	[+] 2 stages ZFS:0000037Larval:Day 5 UBERON:0000066fully formed stage	1.25e4 1.25e4 1.36e4	58.05 58.05 54.38	AEIR AEIR AEIR
UBERON:0000014	zone of skin	[+] 1 stage UBERON:0000066fully formed stage	1.33e4 1.33e4	55.44 55.44	AEIR AEIR
UBERON:0002106	spleen	[+] 1 stage UBERON:0000066fully formed stage	1.34e4 1.34e4	55.22 55.22	AEIR AEIR
UBERON:0000206	pharyngeal gill	[+] 1 stage UBERON:0000066fully formed stage	1.47e4 1.47e4	50.69 50.69	AEIR AEIR
UBERON:0007132	head kidney	[+] 1 stage UBERON:0000066fully formed stage	1.71e4 1.71e4	42.66 42.66	AEIR AEIR
UBERON:0006860	swim bladder	[+] 1 stage UBERON:0000066fully formed stage	1.86e4 1.86e4	37.79 37.79	AEIR AEIR

Sources
A	Affymetrix
E	EST
I	In Situ
R	RNA-Seq

data

no data

Rank scores
3.25e4	lightgrey: low confidence scores
	important score variation

Rank scores of expression calls are normalized across genes, conditions and species. Low score means that the gene is highly expressed in the condition. Max rank score in all species: 4.10e4. Min rank score varies across species.

Expression scores of expression calls use the minimum and maximum Rank of the species to normalize the expression to a value between 0 and 100. Low score means that the gene is lowly expressed in the condition.

Sources of annotations to anatomy and development:

RNA-Seq data: Bgee

Sources of raw data:

RNA-Seq data: GEO

Orthologs

Taxon name	Species with orthologs	Gene(s)	Expression comparison	See details
Euteleostomi	19 species Homo sapiens (human) Mus musculus (mouse) Pan troglodytes (chimpanzee) Gorilla gorilla (gorilla) Macaca mulatta (macaque) Rattus norvegicus (rat) Bos taurus (cattle) Sus scrofa (pig) Equus caballus (horse) Oryctolagus cuniculus (rabbit) Canis lupus familiaris (dog) Felis catus (cat) Cavia porcellus (guinea pig) Erinaceus europaeus (hedgehog) Monodelphis domestica (opossum) Ornithorhynchus anatinus (platypus) Gallus gallus (chicken) Anolis carolinensis (green anole) Xenopus tropicalis (western clawed frog)	19 genes ENSG00000109466 KLHL2 ENSMUSG00000031605 Klhl2 ENSPTRG00000016572 KLHL2 ENSGGOG00000001786 KLHL2 ENSMMUG00000017342 KLHL2 ENSRNOG00000029441 Klhl2 ENSBTAG00000005263 KLHL2 ENSSSCG00000008858 KLHL2 ENSECAG00000010727 KLHL2 ENSOCUG00000003760 KLHL2 ENSCAFG00000008844 KLHL2 ENSFCAG00000008566 KLHL2 ENSCPOG00000005820 KLHL2 ENSEEUG00000015713 KLHL2 ENSMODG00000002334 KLHL2 ENSOANG00000014478 KLHL2 ENSGALG00000009554 KLHL2 ENSACAG00000000301 KLHL2 ENSXETG00000034185 KLHL2	Compare expression	[+]

Orthology information comes from OMA : ENSDARG00000061786.

Paralogs (same species)

Taxon name	Gene(s)	Expression comparison	See details
Chordata	1 gene ENSDARG00000056647 klhl3	Compare expression	[+]
Eumetazoa	3 genes ENSDARG00000037324 klhl17 ENSDARG00000038801 klhl20 ENSDARG00000056647 klhl3	Compare expression	[+]
Eukaryota	10 genes ENSDARG00000004306 klhl18 ENSDARG00000016132 keap1a ENSDARG00000016531 klhl4 ENSDARG00000037324 klhl17 ENSDARG00000038801 klhl20 ENSDARG00000056647 klhl3 ENSDARG00000062122 klhl5 ENSDARG00000074634 keap1b ENSDARG00000090948 si:ch73-29c22.1 ENSDARG00000101270 klhl8	Compare expression	[+]

Paralogy information comes from OMA : ENSDARG00000061786.

Cross-references

Ensembl	ENSDARG00000061786 (klhl2)
ZFIN	ZDB-GENE-090312-193 (klhl2)
EMBL	BX323083, CT583646
Uniprot/SPTREMBL	E9QC48, E9QC48_DANRE