Gene: dyrk1aa - ENSDARG00000063570 - Danio rerio (zebrafish)

General information

Ensembl ID	ENSDARG00000063570
Name	dyrk1aa
Description	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A, a [Source:ZFIN;Acc:ZDB-GENE-050302-29]
Organism	Danio rerio (zebrafish)
Synonym(s)	dyrk1a, im:6962097, zgc:158359
Orthologs(s)	18 orthologs
Paralog(s)	1 paralogs

Expression

Anat. entity ID	Anatomical entity	Developmental stage(s)	Rank score	Expression score	Sources
UBERON:0001630	muscle organ	[+] 1 stage UBERON:0000066fully formed stage	1.16e3 1.16e3	96.12 96.12	AEIR AEIR
UBERON:0000948	heart	[+] 2 stages ZFS:0000036Larval:Day 4 UBERON:0000066fully formed stage	1.91e3 1.91e3 5.81e3	93.62 93.62 80.55	AEIR AEIR AEIR
UBERON:0000473	testis	[+] 1 stage UBERON:0000066fully formed stage	2.09e3 2.09e3	93.01 93.01	AEIR AEIR
UBERON:0002106	spleen	[+] 1 stage UBERON:0000066fully formed stage	2.28e3 2.28e3	92.38 92.38	AEIR AEIR
UBERON:0000922	embryo	[+] 5 stages ZFS:0000033Hatching:Long-pec UBERON:0000068embryo stage ZFS:0000029Pharyngula:Prim-5 ZFS:0000037Larval:Day 5 UBERON:0004707pharyngula stage	2.32e3 2.32e3 3.19e3 3.82e3 4.42e3 4.86e3	92.25 92.25 89.33 87.20 85.20 83.71	AEIR AEIR AEIR AEIR AEIR AEIR
UBERON:0002385	muscle tissue	[+] 1 stage UBERON:0000066fully formed stage	2.72e3 2.72e3	90.88 90.88	AEIR AEIR
UBERON:0002481	bone tissue	[+] 1 stage UBERON:0000066fully formed stage	2.87e3 2.87e3	90.38 90.38	AEIR AEIR
UBERON:0019248	early embryo	[+] 1 stage UBERON:0000107cleavage stage	2.91e3 2.91e3	90.26 90.26	AEIR AEIR
UBERON:0003982	mature ovarian follicle	[+] 1 stage UBERON:0000066fully formed stage	2.91e3 2.91e3	90.25 90.25	AEIR AEIR
UBERON:0000206	pharyngeal gill	[+] 1 stage UBERON:0000066fully formed stage	3.13e3 3.13e3	89.52 89.52	AEIR AEIR
UBERON:0002113	kidney	[+] 1 stage UBERON:0000066fully formed stage	3.22e3 3.22e3	89.21 89.21	AEIR AEIR
UBERON:0000014	zone of skin	[+] 1 stage UBERON:0000066fully formed stage	3.23e3 3.23e3	89.20 89.20	AEIR AEIR
CL:0000094	granulocyte	[+] 1 stage UBERON:0000066fully formed stage	3.28e3 3.28e3	89.01 89.01	AEIR AEIR
UBERON:0002107	liver	[+] 1 stage UBERON:0000066fully formed stage	3.88e3 3.88e3	87.03 87.03	AEIR AEIR
UBERON:0000033	head	[+] 2 stages UBERON:0000066fully formed stage ZFS:0000037Larval:Day 5	4.17e3 4.17e3 5.16e3	86.03 86.03 82.74	AEIR AEIR AEIR
UBERON:0000307	blastula	[+] 2 stages ZFS:0000011Blastula:1k-cell ZFS:0000015Blastula:Dome	4.42e3 4.42e3 5.49e3	85.20 85.20 81.62	AEIR AEIR AEIR
UBERON:0004734	gastrula	[+] 2 stages ZFS:0000022Gastrula:Bud ZFS:0000019Gastrula:Shield	4.76e3 4.76e3 5.62e3	84.06 84.06 81.18	AEIR AEIR AEIR
UBERON:0000160	intestine	[+] 1 stage UBERON:0000066fully formed stage	4.79e3 4.79e3	83.97 83.97	AEIR AEIR
UBERON:0002548	larva	[+] 2 stages UBERON:0000069larval stage ZFS:0000037Larval:Day 5	4.92e3 4.92e3 5.60e3	83.52 83.52 81.24	AEIR AEIR AEIR
UBERON:0000970	eye	[+] 1 stage ZFS:0000031Pharyngula:Prim-25	5.17e3 5.17e3	82.68 82.68	AEIR AEIR
UBERON:0000955	brain	[+] 1 stage UBERON:0000066fully formed stage	5.23e3 5.23e3	82.48 82.48	AEIR AEIR
UBERON:0002415	tail	[+] 1 stage UBERON:0000066fully formed stage	5.75e3 5.75e3	80.75 80.75	AEIR AEIR
UBERON:0000966	retina	[+] 1 stage ZFS:0000037Larval:Day 5	7.38e3 7.38e3	75.29 75.29	AEIR AEIR
UBERON:0007132	head kidney	[+] 1 stage UBERON:0000066fully formed stage	1.34e4 1.34e4	55.15 55.15	AEIR AEIR
UBERON:0006860	swim bladder	[+] 1 stage UBERON:0000066fully formed stage	1.72e4 1.72e4	42.28 42.28	AEIR AEIR

Sources
A	Affymetrix
E	EST
I	In Situ
R	RNA-Seq

data

no data

Rank scores
3.25e4	lightgrey: low confidence scores
	important score variation

Rank scores of expression calls are normalized across genes, conditions and species. Low score means that the gene is highly expressed in the condition. Max rank score in all species: 4.10e4. Min rank score varies across species.

Expression scores of expression calls use the minimum and maximum Rank of the species to normalize the expression to a value between 0 and 100. Low score means that the gene is lowly expressed in the condition.

Sources of annotations to anatomy and development:

RNA-Seq data: Bgee

Sources of raw data:

RNA-Seq data: GEO

Orthologs

Taxon name	Species with orthologs	Gene(s)	Expression comparison	See details
Euteleostomi	18 species Homo sapiens (human) Mus musculus (mouse) Pan troglodytes (chimpanzee) Gorilla gorilla (gorilla) Macaca mulatta (macaque) Rattus norvegicus (rat) Bos taurus (cattle) Sus scrofa (pig) Equus caballus (horse) Oryctolagus cuniculus (rabbit) Canis lupus familiaris (dog) Felis catus (cat) Cavia porcellus (guinea pig) Monodelphis domestica (opossum) Ornithorhynchus anatinus (platypus) Gallus gallus (chicken) Anolis carolinensis (green anole) Xenopus tropicalis (western clawed frog)	18 genes ENSG00000157540 DYRK1A ENSMUSG00000022897 Dyrk1a ENSPTRG00000013901 DYRK1A ENSGGOG00000011897 DYRK1A ENSMMUG00000018131 DYRK1A ENSRNOG00000001662 Dyrk1a ENSBTAG00000001771 DYRK1A ENSSSCG00000030480 ENSECAG00000024965 DYRK1A ENSOCUG00000005814 DYRK1A ENSCAFG00000009801 DYRK1A ENSFCAG00000024560 DYRK1A ENSCPOG00000010097 DYRK1A ENSMODG00000020982 DYRK1A ENSOANG00000006412 DYRK1A ENSGALG00000016053 DYRK1A ENSACAG00000009116 DYRK1A ENSXETG00000013037 dyrk1a	Compare expression	[+]

Orthology information comes from OMA : ENSDARG00000063570.

Paralogs (same species)

Taxon name	Gene(s)	Expression comparison	See details
Euteleostomi	1 gene ENSDARG00000023814 dyrk1ab	Compare expression	[+]

Paralogy information comes from OMA : ENSDARG00000063570.

Cross-references

Ensembl	ENSDARG00000063570 (dyrk1aa)
ZFIN	ZDB-GENE-050302-29 (dyrk1aa)
EMBL	CABZ01076953, CABZ01076954, CU633885
Uniprot/SPTREMBL	E9QFG0, E9QFG0_DANRE, E9QHB0, E9QHB0_DANRE, F1QSN1, F1QSN1_DANRE