Gene: map2k2b - ENSDARG00000068918 - Danio rerio (zebrafish)

General information

Ensembl ID	ENSDARG00000068918
Name	map2k2b
Description	mitogen-activated protein kinase kinase 2b [Source:ZFIN;Acc:ZDB-GENE-080219-34]
Organism	Danio rerio (zebrafish)
Synonym(s)	zgc:172250
Orthologs(s)	26 orthologs
Paralog(s)	17 paralogs

Expression

Anat. entity ID	Anatomical entity	Developmental stage(s)	Rank score	Expression score	Sources
UBERON:0000033	head	[+] 2 stages UBERON:0000066fully formed stage ZFS:0000037Larval:Day 5	5.00e3 5.00e3 1.18e4	83.27 83.27 60.54	AEIR AEIR AEIR
UBERON:0006860	swim bladder	[+] 1 stage UBERON:0000066fully formed stage	5.43e3 5.43e3	81.83 81.83	AEIR AEIR
UBERON:0003982	mature ovarian follicle	[+] 1 stage UBERON:0000066fully formed stage	5.96e3 5.96e3	80.06 80.06	AEIR AEIR
UBERON:0000948	heart	[+] 2 stages UBERON:0000066fully formed stage ZFS:0000036Larval:Day 4	6.60e3 6.60e3 8.68e3	77.92 77.92 70.92	AEIR AEIR AEIR
UBERON:0000966	retina	[+] 1 stage ZFS:0000037Larval:Day 5	7.26e3 7.26e3	75.68 75.68	AEIR AEIR
UBERON:0000922	embryo	[+] 5 stages ZFS:0000033Hatching:Long-pec UBERON:0000068embryo stage ZFS:0000029Pharyngula:Prim-5 UBERON:0004707pharyngula stage ZFS:0000037Larval:Day 5	7.45e3 7.45e3 8.15e3 9.68e3 1.09e4 1.09e4	75.06 75.06 72.70 67.60 63.52 63.39	AEIR AEIR AEIR AEIR AEIR AEIR
UBERON:0000970	eye	[+] 1 stage ZFS:0000031Pharyngula:Prim-25	7.69e3 7.69e3	74.24 74.24	AEIR AEIR
UBERON:0001630	muscle organ	[+] 1 stage UBERON:0000066fully formed stage	7.75e3 7.75e3	74.06 74.06	AEIR AEIR
CL:0000094	granulocyte	[+] 1 stage UBERON:0000066fully formed stage	8.01e3 8.01e3	73.17 73.17	AEIR AEIR
UBERON:0000160	intestine	[+] 1 stage UBERON:0000066fully formed stage	8.47e3 8.47e3	71.65 71.65	AEIR AEIR
UBERON:0002385	muscle tissue	[+] 1 stage UBERON:0000066fully formed stage	8.47e3 8.47e3	71.65 71.65	AEIR AEIR
UBERON:0007132	head kidney	[+] 1 stage UBERON:0000066fully formed stage	8.55e3 8.55e3	71.38 71.38	AEIR AEIR
UBERON:0000206	pharyngeal gill	[+] 1 stage UBERON:0000066fully formed stage	8.62e3 8.62e3	71.14 71.14	AEIR AEIR
UBERON:0000473	testis	[+] 1 stage UBERON:0000066fully formed stage	8.62e3 8.62e3	71.13 71.13	AEIR AEIR
UBERON:0002107	liver	[+] 1 stage UBERON:0000066fully formed stage	8.71e3 8.71e3	70.84 70.84	AEIR AEIR
UBERON:0000955	brain	[+] 1 stage UBERON:0000066fully formed stage	8.87e3 8.87e3	70.29 70.29	AEIR AEIR
UBERON:0002415	tail	[+] 1 stage UBERON:0000066fully formed stage	8.88e3 8.88e3	70.28 70.28	AEIR AEIR
UBERON:0000014	zone of skin	[+] 1 stage UBERON:0000066fully formed stage	8.97e3 8.97e3	69.96 69.96	AEIR AEIR
UBERON:0019248	early embryo	[+] 1 stage UBERON:0000107cleavage stage	9.92e3 9.92e3	66.80 66.80	AEIR AEIR
UBERON:0002481	bone tissue	[+] 1 stage UBERON:0000066fully formed stage	9.98e3 9.98e3	66.57 66.57	AEIR AEIR
UBERON:0004734	gastrula	[+] 2 stages ZFS:0000022Gastrula:Bud ZFS:0000019Gastrula:Shield	1.05e4 1.05e4 1.15e4	64.95 64.95 61.47	AEIR AEIR AEIR
UBERON:0002106	spleen	[+] 1 stage UBERON:0000066fully formed stage	1.10e4 1.10e4	63.05 63.05	AEIR AEIR
UBERON:0002548	larva	[+] 2 stages UBERON:0000069larval stage ZFS:0000037Larval:Day 5	1.18e4 1.18e4 1.40e4	60.56 60.56 53.18	AEIR AEIR AEIR
UBERON:0000307	blastula	[+] 2 stages ZFS:0000011Blastula:1k-cell ZFS:0000015Blastula:Dome	1.21e4 1.21e4 1.27e4	59.54 59.54 57.61	AEIR AEIR AEIR
UBERON:0000019	camera-type eye	[+] 1 stage ZFS:0000035Larval:Protruding-mouth	1.34e4 1.34e4	55.16 55.16	AEIR AEIR

Sources
A	Affymetrix
E	EST
I	In Situ
R	RNA-Seq

data

no data

Rank scores
3.25e4	lightgrey: low confidence scores
	important score variation

Rank scores of expression calls are normalized across genes, conditions and species. Low score means that the gene is highly expressed in the condition. Max rank score in all species: 4.10e4. Min rank score varies across species.

Expression scores of expression calls use the minimum and maximum Rank of the species to normalize the expression to a value between 0 and 100. Low score means that the gene is lowly expressed in the condition.

Sources of annotations to anatomy and development:

EST data: Bgee
RNA-Seq data: Bgee

Sources of raw data:

EST data: UniGene
RNA-Seq data: GEO

Orthologs

Taxon name	Species with orthologs	Gene(s)	Expression comparison	See details
Euteleostomi	16 species Homo sapiens (human) Mus musculus (mouse) Pan troglodytes (chimpanzee) Gorilla gorilla (gorilla) Macaca mulatta (macaque) Rattus norvegicus (rat) Bos taurus (cattle) Sus scrofa (pig) Equus caballus (horse) Canis lupus familiaris (dog) Felis catus (cat) Cavia porcellus (guinea pig) Monodelphis domestica (opossum) Ornithorhynchus anatinus (platypus) Gallus gallus (chicken) Anolis carolinensis (green anole)	19 genes ENSG00000126934 MAP2K2 ENSG00000230626 RP11-286H14.4 ENSMUSG00000035027 Map2k2 ENSPTRG00000010294 MAP2K2 ENSPTRG00000042432 ENSGGOG00000008832 MAP2K2 ENSGGOG00000027737 ENSMMUG00000019564 MAP2K2 ENSRNOG00000020005 Map2k2 ENSBTAG00000024450 MAP2K2 ENSSSCG00000027127 MAP2K2 ENSECAG00000009157 MAP2K2 ENSCAFG00000019138 MAP2K2 ENSFCAG00000014137 MAP2K2 ENSCPOG00000025428 MAP2K2 ENSMODG00000000809 MAP2K2 ENSOANG00000009511 MAP2K2 ENSGALG00000001267 MAP2K2 ENSACAG00000000286 MAP2K2	Compare expression	[+]
Bilateria	23 species Homo sapiens (human) Mus musculus (mouse) Drosophila melanogaster (fruit fly) Caenorhabditis elegans (nematode) Pan troglodytes (chimpanzee) Gorilla gorilla (gorilla) Macaca mulatta (macaque) Rattus norvegicus (rat) Bos taurus (cattle) Sus scrofa (pig) Equus caballus (horse) Canis lupus familiaris (dog) Felis catus (cat) Cavia porcellus (guinea pig) Monodelphis domestica (opossum) Ornithorhynchus anatinus (platypus) Gallus gallus (chicken) Anolis carolinensis (green anole) Drosophila ananassae Drosophila mojavensis Drosophila simulans Drosophila virilis Drosophila yakuba	26 genes ENSG00000126934 MAP2K2 ENSG00000230626 RP11-286H14.4 ENSMUSG00000035027 Map2k2 FBgn0010269 Dsor1 WBGene00003186 mek-2 ENSPTRG00000010294 MAP2K2 ENSPTRG00000042432 ENSGGOG00000008832 MAP2K2 ENSGGOG00000027737 ENSMMUG00000019564 MAP2K2 ENSRNOG00000020005 Map2k2 ENSBTAG00000024450 MAP2K2 ENSSSCG00000027127 MAP2K2 ENSECAG00000009157 MAP2K2 ENSCAFG00000019138 MAP2K2 ENSFCAG00000014137 MAP2K2 ENSCPOG00000025428 MAP2K2 ENSMODG00000000809 MAP2K2 ENSOANG00000009511 MAP2K2 ENSGALG00000001267 MAP2K2 ENSACAG00000000286 MAP2K2 FBgn0082825 Dsor1 FBgn0137987 GI15238 FBgn0063994 Dsor1 FBgn0205985 GJ18839 FBgn0235228 GE17784	Compare expression	[+]

Orthology information comes from OMA : ENSDARG00000068918.

Paralogs (same species)

Taxon name	Gene(s)	Expression comparison	See details
Euteleostomi	1 gene ENSDARG00000006609 map2k2a	Compare expression	[+]
Chordata	2 genes ENSDARG00000006609 map2k2a ENSDARG00000007825 map2k1	Compare expression	[+]
Opisthokonta	17 genes ENSDARG00000006609 map2k2a ENSDARG00000007825 map2k1 ENSDARG00000017446 camk1db ENSDARG00000017994 tssk6 ENSDARG00000029474 camk1b ENSDARG00000043648 pnck ENSDARG00000052923 zgc:113162 ENSDARG00000058869 NEK3 ENSDARG00000060116 camk1a ENSDARG00000063583 map2k4a ENSDARG00000074905 camk1da ENSDARG00000077177 map2k4b ENSDARG00000095902 si:ch211-57m13.10 ENSDARG00000097795 si:ch73-195i19.3 ENSDARG00000099184 map2k6 ENSDARG00000104153 zgc:175248 ENSDARG00000104676 prkd2	Compare expression	[+]

Paralogy information comes from OMA : ENSDARG00000068918.

Cross-references

Ensembl	ENSDARG00000068918 (map2k2b)
ZFIN	ZDB-GENE-080219-34 (map2k2b)
EMBL	CR391909
Uniprot/SPTREMBL	F1QWJ5, F1QWJ5_DANRE