H. sapiens Gene: TYR - ENSG00000077498 - Homo sapiens (human)

General information

Ensembl IDENSG00000077498
NameTYR
Descriptiontyrosinase [Source:HGNC Symbol;Acc:HGNC:12442]
OrganismHomo sapiens (human)
Synonym(s)atn, cmm8, oca1, oca1a, ocaia, q15675, q15676, q15680, q8tak4, q9byy0, q9bzx1, shep3

Expression

Anat. entity IDAnatomical entityDevelopmental stage(s)Rank scoreExpression scoreSources
UBERON:0001782pigmented layer of retina
  • HsapDv:0000198fourth LMP month human stage (human)
  • HsapDv:0000199fifth LMP month human stage (human)
  • HsapDv:000009580 year-old and over human stage (human)
  • HsapDv:000009465-79 year-old human stage (human)
173
  • 173
  • 274
  • 1.24e4
  • 1.72e4
99.69
  • 99.69
  • 99.50
  • 77.50
  • 68.83
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0000014zone of skin
  • UBERON:0000113post-juvenile adult stage
  • HsapDv:0000087human adult stage (human)
  • HsapDv:0000092human middle aged stage (human)
  • UBERON:0000104life cycle
5.07e3
  • 5.07e3
  • 1.64e4
  • 1.81e4
  • 1.91e4
90.79
  • 90.79
  • 70.19
  • 67.10
  • 65.27
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0001416skin of abdomen
  • HsapDv:0000088human early adulthood stage (human)
  • HsapDv:0000087human adult stage (human)
  • HsapDv:000009025-44 year-old human stage (human)
  • HsapDv:0000092human middle aged stage (human)
  • HsapDv:0000091human late adulthood stage (human)
  • HsapDv:000009465-79 year-old human stage (human)
1.02e4
  • 1.02e4
  • 1.16e4
  • 1.26e4
  • 1.27e4
  • 1.44e4
  • 1.49e4
81.51
  • 81.51
  • 78.86
  • 77.07
  • 76.87
  • 73.91
  • 72.85
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0001511skin of leg
  • HsapDv:0000088human early adulthood stage (human)
  • HsapDv:0000087human adult stage (human)
  • HsapDv:000009025-44 year-old human stage (human)
  • HsapDv:0000092human middle aged stage (human)
  • HsapDv:0000091human late adulthood stage (human)
  • HsapDv:000009465-79 year-old human stage (human)
1.07e4
  • 1.07e4
  • 1.21e4
  • 1.23e4
  • 1.26e4
  • 1.27e4
  • 1.35e4
80.63
  • 80.63
  • 77.95
  • 77.68
  • 77.09
  • 76.91
  • 75.49
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0003701calcaneal tendon
  • HsapDv:000009465-79 year-old human stage (human)
  • HsapDv:0000089young adult stage (human)
  • HsapDv:0000092human middle aged stage (human)
  • HsapDv:000009025-44 year-old human stage (human)
  • HsapDv:0000086adolescent stage (human)
1.40e4
  • 1.40e4
  • 1.61e4
  • 1.62e4
  • 1.71e4
  • 1.84e4
74.59
  • 74.59
  • 70.84
  • 70.57
  • 68.98
  • 66.67
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0000997mammalian vulva
  • HsapDv:0000089young adult stage (human)
  • HsapDv:000009025-44 year-old human stage (human)
  • HsapDv:0000092human middle aged stage (human)
1.47e4
  • 1.47e4
  • 1.82e4
  • 1.97e4
73.36
  • 73.36
  • 66.86
  • 64.17
AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0000989penis
  • UBERON:0000104life cycle
1.76e4
  • 1.76e4
67.95
  • 67.95
AEIR
  • AEIR
UBERON:0002084heart left ventricle
  • HsapDv:000009465-79 year-old human stage (human)
  • UBERON:0000104life cycle
  • HsapDv:0000088human early adulthood stage (human)
  • HsapDv:0000091human late adulthood stage (human)
  • HsapDv:0000087human adult stage (human)
2.06e4
  • 2.06e4
  • 3.03e4
  • 3.52e4
  • 3.54e4
  • 4.00e4
62.56
  • 62.56
  • 44.89
  • 35.99
  • 35.74
  • 27.39
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0003729mouth mucosa
  • UBERON:0000104life cycle
  • HsapDv:000009025-44 year-old human stage (human)
2.29e4
  • 2.29e4
  • 2.88e4
58.38
  • 58.38
  • 47.75
AEIR
  • AEIR
  • AEIR
UBERON:0002345descending thoracic aorta
  • HsapDv:0000087human adult stage (human)
2.33e4
  • 2.33e4
57.77
  • 57.77
AEIR
  • AEIR
UBERON:0001496ascending aorta
  • HsapDv:0000091human late adulthood stage (human)
  • HsapDv:0000092human middle aged stage (human)
  • HsapDv:0000087human adult stage (human)
  • HsapDv:0000088human early adulthood stage (human)
  • HsapDv:000009025-44 year-old human stage (human)
2.36e4
  • 2.36e4
  • 2.39e4
  • 2.52e4
  • 2.57e4
  • 2.77e4
57.13
  • 57.13
  • 56.67
  • 54.21
  • 53.41
  • 49.67
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0001515thoracic aorta
  • HsapDv:000009025-44 year-old human stage (human)
  • HsapDv:0000087human adult stage (human)
  • HsapDv:0000092human middle aged stage (human)
  • HsapDv:0000088human early adulthood stage (human)
2.39e4
  • 2.39e4
  • 2.44e4
  • 2.53e4
  • 2.89e4
56.60
  • 56.60
  • 55.71
  • 54.03
  • 47.48
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0001830minor salivary gland
  • HsapDv:0000087human adult stage (human)
  • HsapDv:0000091human late adulthood stage (human)
  • HsapDv:000009025-44 year-old human stage (human)
  • HsapDv:0000088human early adulthood stage (human)
  • HsapDv:0000092human middle aged stage (human)
2.63e4
  • 2.63e4
  • 2.93e4
  • 2.98e4
  • 3.05e4
  • 3.16e4
52.32
  • 52.32
  • 46.78
  • 45.91
  • 44.67
  • 42.65
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0000167oral cavity
  • HsapDv:0000092human middle aged stage (human)
  • HsapDv:0000087human adult stage (human)
  • HsapDv:0000088human early adulthood stage (human)
  • HsapDv:0000091human late adulthood stage (human)
2.64e4
  • 2.64e4
  • 2.91e4
  • 2.95e4
  • 3.23e4
52.08
  • 52.08
  • 47.08
  • 46.34
  • 41.35
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0000473testis
  • HsapDv:0000197third LMP month human stage (human)
  • UBERON:0034920infant stage
  • UBERON:0000113post-juvenile adult stage
  • UBERON:0000104life cycle
  • HsapDv:000009025-44 year-old human stage (human)
  • HsapDv:0000092human middle aged stage (human)
2.65e4
  • 2.65e4
  • 3.05e4
  • 3.30e4
  • 3.59e4
  • 3.59e4
  • 4.15e4
51.93
  • 51.93
  • 44.65
  • 40.10
  • 34.76
  • 34.73
  • 24.67
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0007610tibial artery
  • HsapDv:0000092human middle aged stage (human)
  • HsapDv:0000087human adult stage (human)
  • HsapDv:0000091human late adulthood stage (human)
  • HsapDv:0000088human early adulthood stage (human)
  • HsapDv:000009025-44 year-old human stage (human)
2.85e4
  • 2.85e4
  • 2.92e4
  • 3.01e4
  • 3.22e4
  • 3.63e4
48.30
  • 48.30
  • 47.05
  • 45.42
  • 41.45
  • 34.16
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0000178blood
  • UBERON:0000104life cycle
  • HsapDv:000009025-44 year-old human stage (human)
  • UBERON:0000113post-juvenile adult stage
  • HsapDv:0000087human adult stage (human)
  • HsapDv:0000088human early adulthood stage (human)
  • HsapDv:0000091human late adulthood stage (human)
3.08e4
  • 3.08e4
  • 3.43e4
  • 3.62e4
  • 3.79e4
  • 3.98e4
  • 4.02e4
44.01
  • 44.01
  • 37.71
  • 34.31
  • 31.09
  • 27.75
  • 27.03
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0001013adipose tissue
  • HsapDv:000009025-44 year-old human stage (human)
  • UBERON:0000104life cycle
  • HsapDv:0000092human middle aged stage (human)
  • UBERON:0000113post-juvenile adult stage
3.10e4
  • 3.10e4
  • 3.16e4
  • 3.16e4
  • 4.05e4
43.71
  • 43.71
  • 42.64
  • 42.57
  • 26.40
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0000955brain
  • HsapDv:0000092human middle aged stage (human)
  • UBERON:0007220late embryonic stage
  • UBERON:0000104life cycle
  • HsapDv:0000087human adult stage (human)
3.10e4
  • 3.10e4
  • 3.21e4
  • 3.58e4
  • 4.01e4
43.62
  • 43.62
  • 41.78
  • 34.92
  • 27.12
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0000451prefrontal cortex
  • HsapDv:0000086adolescent stage (human)
  • UBERON:0000104life cycle
3.12e4
  • 3.12e4
  • 3.71e4
43.28
  • 43.28
  • 32.59
AEIR
  • AEIR
  • AEIR
UBERON:0001890forebrain
  • HsapDv:0000198fourth LMP month human stage (human)
  • HsapDv:0000199fifth LMP month human stage (human)
3.15e4
  • 3.15e4
  • 3.16e4
42.75
  • 42.75
  • 42.57
AEIR
  • AEIR
  • AEIR
UBERON:0002048lung
  • UBERON:0000104life cycle
  • UBERON:0000113post-juvenile adult stage
3.16e4
  • 3.16e4
  • 3.82e4
42.70
  • 42.70
  • 30.56
AEIR
  • AEIR
  • AEIR
UBERON:0001950neocortex
  • HsapDv:0000199fifth LMP month human stage (human)
3.16e4
  • 3.16e4
42.58
  • 42.58
AEIR
  • AEIR
UBERON:0004533left testis
  • HsapDv:0000088human early adulthood stage (human)
  • HsapDv:000009025-44 year-old human stage (human)
  • HsapDv:0000092human middle aged stage (human)
  • HsapDv:0000091human late adulthood stage (human)
  • HsapDv:0000087human adult stage (human)
3.16e4
  • 3.16e4
  • 3.18e4
  • 3.22e4
  • 3.27e4
  • 3.45e4
42.53
  • 42.53
  • 42.31
  • 41.60
  • 40.57
  • 37.39
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0000956cerebral cortex
  • HsapDv:0000198fourth LMP month human stage (human)
  • HsapDv:0000092human middle aged stage (human)
  • UBERON:0000113post-juvenile adult stage
3.17e4
  • 3.17e4
  • 3.22e4
  • 3.99e4
42.38
  • 42.38
  • 41.43
  • 27.60
AEIR
  • AEIR
  • AEIR
  • AEIR
PBA:294021980subventricular zone (outer) (primate)
  • HsapDv:0000198fourth LMP month human stage (human)
3.18e4
  • 3.18e4
42.30
  • 42.30
AEIR
  • AEIR
UBERON:0000995uterus
  • UBERON:0000104life cycle
3.20e4
  • 3.20e4
41.83
  • 41.83
AEIR
  • AEIR
UBERON:0001295endometrium
  • UBERON:0000104life cycle
  • UBERON:0000113post-juvenile adult stage
3.20e4
  • 3.20e4
  • 4.08e4
41.81
  • 41.81
  • 25.82
AEIR
  • AEIR
  • AEIR
UBERON:0000059large intestine
  • UBERON:0000104life cycle
3.21e4
  • 3.21e4
41.78
  • 41.78
AEIR
  • AEIR
UBERON:0001155colon
  • UBERON:0000104life cycle
  • UBERON:0000113post-juvenile adult stage
3.21e4
  • 3.21e4
  • 3.97e4
41.78
  • 41.78
  • 27.91
AEIR
  • AEIR
  • AEIR
UBERON:0005343cortical plate
  • HsapDv:0000199fifth LMP month human stage (human)
3.21e4
  • 3.21e4
41.74
  • 41.74
AEIR
  • AEIR
UBERON:0001043esophagus
  • HsapDv:000009025-44 year-old human stage (human)
  • UBERON:0000113post-juvenile adult stage
  • HsapDv:0000087human adult stage (human)
3.21e4
  • 3.21e4
  • 3.87e4
  • 4.55e4
41.67
  • 41.67
  • 29.72
  • 17.43
AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0002371bone marrow
  • UBERON:0000104life cycle
  • UBERON:0000113post-juvenile adult stage
3.23e4
  • 3.23e4
  • 3.31e4
41.40
  • 41.40
  • 39.95
AEIR
  • AEIR
  • AEIR
UBERON:0003889fallopian tube
  • UBERON:0000104life cycle
  • UBERON:0000113post-juvenile adult stage
3.23e4
  • 3.23e4
  • 3.77e4
41.32
  • 41.32
  • 31.51
AEIR
  • AEIR
  • AEIR
UBERON:0001873caudate nucleus
  • UBERON:0000104life cycle
  • HsapDv:0000087human adult stage (human)
  • HsapDv:0000091human late adulthood stage (human)
3.24e4
  • 3.24e4
  • 3.37e4
  • 3.37e4
41.21
  • 41.21
  • 38.86
  • 38.83
AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0002113kidney
  • UBERON:0000104life cycle
3.30e4
  • 3.30e4
40.06
  • 40.06
AEIR
  • AEIR
UBERON:0000996vagina
  • HsapDv:000009025-44 year-old human stage (human)
  • HsapDv:0000092human middle aged stage (human)
  • HsapDv:0000091human late adulthood stage (human)
  • HsapDv:0000087human adult stage (human)
  • HsapDv:0000088human early adulthood stage (human)
3.36e4
  • 3.36e4
  • 3.91e4
  • 4.05e4
  • 4.26e4
  • 4.63e4
39.04
  • 39.04
  • 29.00
  • 26.43
  • 22.69
  • 15.87
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0002190subcutaneous adipose tissue
  • HsapDv:000009025-44 year-old human stage (human)
  • HsapDv:0000087human adult stage (human)
  • HsapDv:0000091human late adulthood stage (human)
  • HsapDv:0000092human middle aged stage (human)
  • HsapDv:0000088human early adulthood stage (human)
3.38e4
  • 3.38e4
  • 3.41e4
  • 3.41e4
  • 3.53e4
  • 3.72e4
38.67
  • 38.67
  • 38.07
  • 37.99
  • 35.86
  • 32.50
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0006631right atrium auricular region
  • HsapDv:0000091human late adulthood stage (human)
  • HsapDv:0000087human adult stage (human)
3.41e4
  • 3.41e4
  • 3.74e4
38.12
  • 38.12
  • 32.16
AEIR
  • AEIR
  • AEIR
UBERON:0001323tibial nerve
  • HsapDv:0000088human early adulthood stage (human)
  • HsapDv:0000092human middle aged stage (human)
  • HsapDv:0000091human late adulthood stage (human)
  • HsapDv:0000087human adult stage (human)
3.47e4
  • 3.47e4
  • 3.53e4
  • 3.61e4
  • 3.77e4
37.07
  • 37.07
  • 35.94
  • 34.50
  • 31.46
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0001954Ammon's horn
  • HsapDv:0000092human middle aged stage (human)
  • HsapDv:0000087human adult stage (human)
  • HsapDv:0000091human late adulthood stage (human)
3.59e4
  • 3.59e4
  • 3.64e4
  • 3.86e4
34.80
  • 34.80
  • 33.97
  • 29.92
AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0009835anterior cingulate cortex
  • HsapDv:0000091human late adulthood stage (human)
  • HsapDv:0000087human adult stage (human)
3.60e4
  • 3.60e4
  • 3.65e4
34.60
  • 34.60
  • 33.69
AEIR
  • AEIR
  • AEIR
UBERON:0001388gastrocnemius
  • HsapDv:0000087human adult stage (human)
  • HsapDv:0000091human late adulthood stage (human)
  • HsapDv:0000092human middle aged stage (human)
3.82e4
  • 3.82e4
  • 3.84e4
  • 3.94e4
30.54
  • 30.54
  • 30.24
  • 28.49
AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0002110gall bladder
  • UBERON:0000113post-juvenile adult stage
3.98e4
  • 3.98e4
27.76
  • 27.76
AEIR
  • AEIR
UBERON:0008952upper lobe of left lung
  • HsapDv:0000091human late adulthood stage (human)
  • HsapDv:0000087human adult stage (human)
4.00e4
  • 4.00e4
  • 4.05e4
27.35
  • 27.35
  • 26.53
AEIR
  • AEIR
  • AEIR
UBERON:0001157transverse colon
  • HsapDv:0000091human late adulthood stage (human)
  • HsapDv:0000087human adult stage (human)
4.10e4
  • 4.10e4
  • 4.28e4
25.49
  • 25.49
  • 22.19
AEIR
  • AEIR
  • AEIR
UBERON:0002469esophagus mucosa
  • HsapDv:0000087human adult stage (human)
  • HsapDv:000009025-44 year-old human stage (human)
  • HsapDv:0000088human early adulthood stage (human)
4.22e4
  • 4.22e4
  • 4.25e4
  • 4.43e4
23.44
  • 23.44
  • 22.86
  • 19.51
AEIR
  • AEIR
  • AEIR
  • AEIR
Sources
AAffymetrix
EEST
IIn Situ
RRNA-Seq
data
no data
Rank scores
3.25e4lightgrey: low confidence scores

important score variation

Rank scores of expression calls are normalized across genes, conditions and species. Low score means that the gene is highly expressed in the condition. Max rank score in all species: 4.10e4. Min rank score varies across species.

Expression scores of expression calls use the minimum and maximum Rank of the species to normalize the expression to a value between 0 and 100. Low score means that the gene is lowly expressed in the condition.

Sources of annotations to anatomy and development:
Sources of raw data:

Cross-references

CCDSCCDS8284 (CCDS8284.1)
EMBLAB775900, AF237807, AF237808, AF237809, AF237810, AF237811, AY012019, BC027179, CH471185, J03581, KC201429, KC201430, KC201431, KC201433, KC201434, KC201435, KC201436, KC201437, KC201438, KC201439, KC201440, KC201441, KC201442, KC201443, KC201444, KC201445, KC201446, KC201447, KC201448, KC201449, KC201450, KC201451, KC201452, KC201453, KC201454, KC201455, KC201456, KC201457, KC201458, KC201459, KC201463, KC201466, KC201471, KC201472, KC201475, KC201476, KC201477, KC201478, KC201479, KC201481, KC201483, KC201484, KC201485, KC201486, KC201487, KC201488, KC201489, KC201490, KC201491, KC201492, KC201493, KC201494, KC201495, KC201496, KC201497, KC201498, KC201499, KC201502, KC201503, KC201504, KC201505, KC201506, KC201507, KC201508, KC201509, KC201511, KC201512, KC201513, KC201514, KC201515, KC201516, KC201517, KC201518, KC201519, KC201520, KC201521, KC201522, KC201523, KC201524, KC201525, KC201526, KC201527, KC201528, KC201529, KC201530, KC201531, KC201532, KC201533, KC201534, KC201535, KC201536, KC201537, KC201538, KC201539, KC201541, KC201547, KC201552, KC201555, KC201556, KC201557, KC201558, KC201559, KC201560, KC201561, KC201562, KC201563, KC201564, KC201565, KC201567, KC201568, KC201569, KC201571, KC201573, KC201574, KC201575, KC201576, KC201577, KC201578, KC201579, KC201580, KC201581, KC201582, KC201583, KC201584, KC201585, KC201586, KC201587, KC201588, M27160, M63235, M63236, M63237, M63238, M63239, M74314, U01873, X16073, Y00819
EnsemblENSG00000077498 (TYR)
HGNCHGNC:12442 (TYR)
OncoMXTYR (TYR)
Uniprot/SPTREMBLL8B082, L8B082_HUMAN
Uniprot/SWISSPROTP14679, TYRO_HUMAN

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