H. sapiens Gene: TYR - ENSG00000077498 - Homo sapiens (human)

General information

Ensembl IDENSG00000077498
NameTYR
Descriptiontyrosinase [Source:HGNC Symbol;Acc:HGNC:12442]
OrganismHomo sapiens (human)
Synonym(s)atn, cmm8, oca1, oca1a, ocaia, q15675, q15676, q15680, q8tak4, q9byy0, q9bzx1, shep3

Expression

Anat. entity IDAnatomical entityDevelopmental stage(s)Rank scoreExpression scoreSources
UBERON:0001782pigmented layer of retina
  • HsapDv:0000198fourth LMP month human stage (human)
  • HsapDv:0000199fifth LMP month human stage (human)
  • HsapDv:000009580 year-old and over human stage (human)
  • HsapDv:000009465-79 year-old human stage (human)
171
  • 171
  • 271
  • 1.22e4
  • 1.70e4
99.68610
  • 99.68610
  • 99.50174
  • 77.39470
  • 68.68159
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0001416skin of abdomen
  • HsapDv:0000088human early adulthood stage (human)
  • HsapDv:0000087human adult stage (human)
  • HsapDv:000009025-44 year-old human stage (human)
  • HsapDv:0000092human middle aged stage (human)
  • HsapDv:0000091human late adulthood stage (human)
  • HsapDv:000009465-79 year-old human stage (human)
1.02e4
  • 1.02e4
  • 1.16e4
  • 1.26e4
  • 1.27e4
  • 1.44e4
  • 1.49e4
81.19037
  • 81.19037
  • 78.50122
  • 76.68039
  • 76.48286
  • 73.47868
  • 72.39034
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0001511skin of leg
  • HsapDv:0000088human early adulthood stage (human)
  • HsapDv:0000087human adult stage (human)
  • HsapDv:000009025-44 year-old human stage (human)
  • HsapDv:0000092human middle aged stage (human)
  • HsapDv:0000091human late adulthood stage (human)
  • HsapDv:000009465-79 year-old human stage (human)
1.07e4
  • 1.07e4
  • 1.21e4
  • 1.23e4
  • 1.26e4
  • 1.27e4
  • 1.35e4
80.29901
  • 80.29901
  • 77.57128
  • 77.29999
  • 76.69434
  • 76.52375
  • 75.07361
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0000997mammalian vulva
  • HsapDv:0000089young adult stage (human)
  • HsapDv:000009025-44 year-old human stage (human)
  • HsapDv:0000092human middle aged stage (human)
1.45e4
  • 1.45e4
  • 1.80e4
  • 1.95e4
73.23464
  • 73.23464
  • 66.70381
  • 64.00041
AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0000989penis
  • UBERON:0000104life cycle
1.74e4
  • 1.74e4
67.79997
  • 67.79997
AEIR
  • AEIR
UBERON:0002084heart left ventricle
  • HsapDv:000009465-79 year-old human stage (human)
  • UBERON:0000104life cycle
  • HsapDv:0000088human early adulthood stage (human)
  • HsapDv:0000091human late adulthood stage (human)
  • HsapDv:0000087human adult stage (human)
2.06e4
  • 2.06e4
  • 3.00e4
  • 3.51e4
  • 3.52e4
  • 3.97e4
61.91954
  • 61.91954
  • 44.62721
  • 35.18658
  • 34.92931
  • 26.57887
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0003729mouth mucosa
  • UBERON:0000104life cycle
  • HsapDv:000009025-44 year-old human stage (human)
2.26e4
  • 2.26e4
  • 2.84e4
58.18857
  • 58.18857
  • 47.50881
AEIR
  • AEIR
  • AEIR
UBERON:0002345descending thoracic aorta
  • HsapDv:0000087human adult stage (human)
2.33e4
  • 2.33e4
57.04588
  • 57.04588
AEIR
  • AEIR
UBERON:0001496ascending aorta
  • HsapDv:0000091human late adulthood stage (human)
  • HsapDv:0000092human middle aged stage (human)
  • HsapDv:0000087human adult stage (human)
  • HsapDv:0000088human early adulthood stage (human)
  • HsapDv:000009025-44 year-old human stage (human)
2.36e4
  • 2.36e4
  • 2.39e4
  • 2.52e4
  • 2.56e4
  • 2.77e4
56.40140
  • 56.40140
  • 55.94414
  • 53.43393
  • 52.62331
  • 48.88775
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0001515thoracic aorta
  • HsapDv:000009025-44 year-old human stage (human)
  • HsapDv:0000087human adult stage (human)
  • HsapDv:0000092human middle aged stage (human)
  • HsapDv:0000088human early adulthood stage (human)
2.39e4
  • 2.39e4
  • 2.52e4
  • 2.53e4
  • 2.89e4
55.86413
  • 55.86413
  • 53.42802
  • 53.24659
  • 46.59758
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0000167oral cavity
  • HsapDv:0000092human middle aged stage (human)
  • HsapDv:0000087human adult stage (human)
  • HsapDv:0000088human early adulthood stage (human)
  • HsapDv:0000091human late adulthood stage (human)
2.61e4
  • 2.61e4
  • 2.88e4
  • 2.92e4
  • 3.19e4
51.85546
  • 51.85546
  • 46.82977
  • 46.09110
  • 41.07389
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0000473testis
  • HsapDv:0000197third LMP month human stage (human)
  • UBERON:0000104life cycle
  • HsapDv:000009025-44 year-old human stage (human)
  • HsapDv:0000092human middle aged stage (human)
2.61e4
  • 2.61e4
  • 3.26e4
  • 3.56e4
  • 4.13e4
51.70034
  • 51.70034
  • 39.87235
  • 34.32167
  • 23.76612
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0001830minor salivary gland
  • HsapDv:0000087human adult stage (human)
  • HsapDv:0000091human late adulthood stage (human)
  • HsapDv:000009025-44 year-old human stage (human)
  • HsapDv:0000088human early adulthood stage (human)
  • HsapDv:0000092human middle aged stage (human)
2.62e4
  • 2.62e4
  • 2.93e4
  • 2.97e4
  • 3.05e4
  • 3.15e4
51.58092
  • 51.58092
  • 45.92674
  • 45.09516
  • 43.74656
  • 41.85253
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0007610tibial artery
  • HsapDv:0000092human middle aged stage (human)
  • HsapDv:0000087human adult stage (human)
  • HsapDv:0000091human late adulthood stage (human)
  • HsapDv:0000088human early adulthood stage (human)
  • HsapDv:000009025-44 year-old human stage (human)
2.84e4
  • 2.84e4
  • 2.92e4
  • 3.00e4
  • 3.21e4
  • 3.61e4
47.52121
  • 47.52121
  • 46.10604
  • 44.60595
  • 40.64378
  • 33.37244
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0000178blood
  • UBERON:0000104life cycle
  • UBERON:0000113post-juvenile adult stage
  • HsapDv:000009025-44 year-old human stage (human)
  • HsapDv:0000087human adult stage (human)
  • HsapDv:0000088human early adulthood stage (human)
  • HsapDv:0000091human late adulthood stage (human)
3.05e4
  • 3.05e4
  • 3.05e4
  • 3.40e4
  • 3.78e4
  • 3.95e4
  • 3.99e4
43.75024
  • 43.75024
  • 43.65396
  • 37.20980
  • 30.17304
  • 26.97432
  • 26.25260
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0001013adipose tissue
  • HsapDv:000009025-44 year-old human stage (human)
  • UBERON:0000104life cycle
  • HsapDv:0000092human middle aged stage (human)
3.06e4
  • 3.06e4
  • 3.12e4
  • 3.12e4
43.45066
  • 43.45066
  • 42.37240
  • 42.30190
AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0000955brain
  • HsapDv:0000092human middle aged stage (human)
  • UBERON:0000104life cycle
  • HsapDv:0000087human adult stage (human)
3.07e4
  • 3.07e4
  • 3.26e4
  • 3.96e4
43.35230
  • 43.35230
  • 39.70317
  • 26.94698
AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0002048lung
  • UBERON:0000104life cycle
3.12e4
  • 3.12e4
42.43025
  • 42.43025
AEIR
  • AEIR
UBERON:0004533left testis
  • HsapDv:0000088human early adulthood stage (human)
  • HsapDv:000009025-44 year-old human stage (human)
  • HsapDv:0000092human middle aged stage (human)
  • HsapDv:0000091human late adulthood stage (human)
  • HsapDv:0000087human adult stage (human)
3.16e4
  • 3.16e4
  • 3.18e4
  • 3.22e4
  • 3.27e4
  • 3.45e4
41.55680
  • 41.55680
  • 41.33827
  • 40.61618
  • 39.56439
  • 36.34240
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0000059large intestine
  • UBERON:0000104life cycle
3.17e4
  • 3.17e4
41.50918
  • 41.50918
AEIR
  • AEIR
UBERON:0001155colon
  • UBERON:0000104life cycle
3.17e4
  • 3.17e4
41.50406
  • 41.50406
AEIR
  • AEIR
UBERON:0001043esophagus
  • HsapDv:000009025-44 year-old human stage (human)
  • HsapDv:0000087human adult stage (human)
3.17e4
  • 3.17e4
  • 4.51e4
41.39880
  • 41.39880
  • 16.61954
AEIR
  • AEIR
  • AEIR
UBERON:0000956cerebral cortex
  • HsapDv:0000092human middle aged stage (human)
3.19e4
  • 3.19e4
41.16013
  • 41.16013
AEIR
  • AEIR
UBERON:0001873caudate nucleus
  • UBERON:0000104life cycle
  • HsapDv:0000087human adult stage (human)
  • HsapDv:0000091human late adulthood stage (human)
3.20e4
  • 3.20e4
  • 3.36e4
  • 3.36e4
40.93457
  • 40.93457
  • 37.91644
  • 37.91601
AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0000996vagina
  • HsapDv:000009025-44 year-old human stage (human)
  • HsapDv:0000092human middle aged stage (human)
  • HsapDv:0000091human late adulthood stage (human)
  • HsapDv:0000087human adult stage (human)
  • HsapDv:0000088human early adulthood stage (human)
3.33e4
  • 3.33e4
  • 3.88e4
  • 4.03e4
  • 4.23e4
  • 4.60e4
38.45224
  • 38.45224
  • 28.27841
  • 25.52228
  • 21.83204
  • 15.04346
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0002190subcutaneous adipose tissue
  • HsapDv:000009025-44 year-old human stage (human)
  • HsapDv:0000087human adult stage (human)
  • HsapDv:0000091human late adulthood stage (human)
  • HsapDv:0000092human middle aged stage (human)
  • HsapDv:0000088human early adulthood stage (human)
3.36e4
  • 3.36e4
  • 3.36e4
  • 3.40e4
  • 3.52e4
  • 3.70e4
37.88371
  • 37.88371
  • 37.85162
  • 37.12814
  • 35.01302
  • 31.67575
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0006631right atrium auricular region
  • HsapDv:0000091human late adulthood stage (human)
  • HsapDv:0000087human adult stage (human)
3.40e4
  • 3.40e4
  • 3.72e4
37.26963
  • 37.26963
  • 31.33054
AEIR
  • AEIR
  • AEIR
UBERON:0001323tibial nerve
  • HsapDv:0000088human early adulthood stage (human)
  • HsapDv:0000092human middle aged stage (human)
  • HsapDv:0000091human late adulthood stage (human)
  • HsapDv:0000087human adult stage (human)
3.45e4
  • 3.45e4
  • 3.52e4
  • 3.60e4
  • 3.75e4
36.20043
  • 36.20043
  • 35.06108
  • 33.58368
  • 30.66144
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0001954Ammon's horn
  • HsapDv:0000092human middle aged stage (human)
  • HsapDv:0000087human adult stage (human)
  • HsapDv:0000091human late adulthood stage (human)
3.57e4
  • 3.57e4
  • 3.62e4
  • 3.84e4
34.11029
  • 34.11029
  • 33.11457
  • 29.06439
AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0009835anterior cingulate cortex
  • HsapDv:0000091human late adulthood stage (human)
  • HsapDv:0000087human adult stage (human)
3.59e4
  • 3.59e4
  • 3.64e4
33.71438
  • 33.71438
  • 32.80088
AEIR
  • AEIR
  • AEIR
UBERON:0001388gastrocnemius
  • HsapDv:0000087human adult stage (human)
  • HsapDv:0000091human late adulthood stage (human)
  • HsapDv:0000092human middle aged stage (human)
3.81e4
  • 3.81e4
  • 3.82e4
  • 3.91e4
29.54128
  • 29.54128
  • 29.46204
  • 27.70075
AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0008952upper lobe of left lung
  • HsapDv:0000091human late adulthood stage (human)
  • HsapDv:0000087human adult stage (human)
3.98e4
  • 3.98e4
  • 4.03e4
26.48790
  • 26.48790
  • 25.61120
AEIR
  • AEIR
  • AEIR
UBERON:0001157transverse colon
  • HsapDv:0000091human late adulthood stage (human)
  • HsapDv:0000087human adult stage (human)
4.08e4
  • 4.08e4
  • 4.27e4
24.65241
  • 24.65241
  • 21.19554
AEIR
  • AEIR
  • AEIR
UBERON:0002469esophagus mucosa
  • HsapDv:0000087human adult stage (human)
  • HsapDv:000009025-44 year-old human stage (human)
  • HsapDv:0000088human early adulthood stage (human)
4.19e4
  • 4.19e4
  • 4.22e4
  • 4.40e4
22.59742
  • 22.59742
  • 22.03168
  • 18.69380
AEIR
  • AEIR
  • AEIR
  • AEIR
Sources
AAffymetrix
EEST
IIn Situ
RRNA-Seq
data
no data
Rank scores
3.25e4lightgrey: low confidence scores

important score variation

Rank scores of expression calls are normalized across genes, conditions and species. Low score means that the gene is highly expressed in the condition. Max rank score in all species: 4.10e4. Min rank score varies across species.

Expression scores of expression calls use the minimum and maximum Rank of the species to normalize the expression to a value between 0 and 100. Low score means that the gene is lowly expressed in the condition.

Sources of annotations to anatomy and development:
  • Affymetrix data: Bgee
  • RNA-Seq data: Bgee
Sources of raw data:

Cross-references

CCDSCCDS8284 (CCDS8284.1)
EMBLAB775900, AF237807, AF237808, AF237809, AF237810, AF237811, AY012019, BC027179, CH471185, J03581, KC201429, KC201430, KC201431, KC201433, KC201434, KC201435, KC201436, KC201437, KC201438, KC201439, KC201440, KC201441, KC201442, KC201443, KC201444, KC201445, KC201446, KC201447, KC201448, KC201449, KC201450, KC201451, KC201452, KC201453, KC201454, KC201455, KC201456, KC201457, KC201458, KC201459, KC201463, KC201466, KC201471, KC201472, KC201475, KC201476, KC201477, KC201478, KC201479, KC201481, KC201483, KC201484, KC201485, KC201486, KC201487, KC201488, KC201489, KC201490, KC201491, KC201492, KC201493, KC201494, KC201495, KC201496, KC201497, KC201498, KC201499, KC201502, KC201503, KC201504, KC201505, KC201506, KC201507, KC201508, KC201509, KC201511, KC201512, KC201513, KC201514, KC201515, KC201516, KC201517, KC201518, KC201519, KC201520, KC201521, KC201522, KC201523, KC201524, KC201525, KC201526, KC201527, KC201528, KC201529, KC201530, KC201531, KC201532, KC201533, KC201534, KC201535, KC201536, KC201537, KC201538, KC201539, KC201541, KC201547, KC201552, KC201555, KC201556, KC201557, KC201558, KC201559, KC201560, KC201561, KC201562, KC201563, KC201564, KC201565, KC201567, KC201568, KC201569, KC201571, KC201573, KC201574, KC201575, KC201576, KC201577, KC201578, KC201579, KC201580, KC201581, KC201582, KC201583, KC201584, KC201585, KC201586, KC201587, KC201588, M27160, M63235, M63236, M63237, M63238, M63239, M74314, U01873, X16073, Y00819
EnsemblENSG00000077498 (TYR)
HGNCHGNC:12442 (TYR)
OncoMXTYR (TYR)
Uniprot/SPTREMBLL8B082, L8B082_HUMAN
Uniprot/SWISSPROTP14679, TYRO_HUMAN

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