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H. sapiens Gene: NKX2-4 - ENSG00000125816 - Homo sapiens (human)

General information

Ensembl IDENSG00000125816
NameNKX2-4
DescriptionNK2 homeobox 4 [Source:HGNC Symbol;Acc:HGNC:7837]
OrganismHomo sapiens (human)
Synonym(s)nkx2.4, nkx2d, q5vzv8
Orthologs(s)9 orthologs

Expression

Anat. entity IDAnatomical entityDevelopmental stage(s)Rank scoreExpression scoreSources
UBERON:0001898hypothalamus
  • HsapDv:000009465-79 year-old human stage (human)
  • HsapDv:0000087human adult stage (human)
  • HsapDv:0000091human late adulthood stage (human)
  • HsapDv:0000092human middle aged stage (human)
1.99e4
  • 1.99e4
  • 2.52e4
  • 2.78e4
  • 2.88e4
63.82
  • 63.82
  • 54.18
  • 49.51
  • 47.67
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0000473testis
  • HsapDv:0000092human middle aged stage (human)
  • HsapDv:000009025-44 year-old human stage (human)
  • UBERON:0000113post-juvenile adult stage
  • HsapDv:0000089young adult stage (human)
  • HsapDv:000009580 year-old and over human stage (human)
  • UBERON:0034920infant stage
  • UBERON:0000104life cycle
2.03e4
  • 2.03e4
  • 2.04e4
  • 2.32e4
  • 2.36e4
  • 2.41e4
  • 2.43e4
  • 4.16e4
63.20
  • 63.20
  • 62.89
  • 57.87
  • 57.11
  • 56.31
  • 55.93
  • 24.46
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0006469C1 segment of cervical spinal cord
  • HsapDv:000009465-79 year-old human stage (human)
  • HsapDv:0000091human late adulthood stage (human)
  • HsapDv:0000087human adult stage (human)
2.08e4
  • 2.08e4
  • 3.41e4
  • 3.49e4
62.26
  • 62.26
  • 38.02
  • 36.68
AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0004534right testis
  • HsapDv:000009025-44 year-old human stage (human)
  • HsapDv:0000088human early adulthood stage (human)
  • HsapDv:0000087human adult stage (human)
  • HsapDv:0000091human late adulthood stage (human)
  • HsapDv:0000092human middle aged stage (human)
2.11e4
  • 2.11e4
  • 2.30e4
  • 2.34e4
  • 2.38e4
  • 2.40e4
61.73
  • 61.73
  • 58.19
  • 57.58
  • 56.78
  • 56.41
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0004533left testis
  • HsapDv:0000091human late adulthood stage (human)
  • HsapDv:0000087human adult stage (human)
  • HsapDv:0000088human early adulthood stage (human)
  • HsapDv:0000092human middle aged stage (human)
  • HsapDv:000009025-44 year-old human stage (human)
  • HsapDv:000009465-79 year-old human stage (human)
2.32e4
  • 2.32e4
  • 2.36e4
  • 2.39e4
  • 2.39e4
  • 2.39e4
  • 2.53e4
57.86
  • 57.86
  • 57.11
  • 56.63
  • 56.59
  • 56.56
  • 54.00
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0000007pituitary gland
  • HsapDv:000009465-79 year-old human stage (human)
  • HsapDv:0000092human middle aged stage (human)
  • HsapDv:0000091human late adulthood stage (human)
  • HsapDv:0000087human adult stage (human)
2.53e4
  • 2.53e4
  • 3.15e4
  • 3.22e4
  • 3.67e4
54.09
  • 54.09
  • 42.84
  • 41.48
  • 33.39
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0002196adenohypophysis
  • HsapDv:0000092human middle aged stage (human)
  • HsapDv:0000091human late adulthood stage (human)
  • HsapDv:0000087human adult stage (human)
2.79e4
  • 2.79e4
  • 2.99e4
  • 3.29e4
49.26
  • 49.26
  • 45.70
  • 40.34
AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0001882nucleus accumbens
  • HsapDv:0000091human late adulthood stage (human)
  • HsapDv:0000087human adult stage (human)
4.08e4
  • 4.08e4
  • 4.29e4
25.99
  • 25.99
  • 22.04
AEIR
  • AEIR
  • AEIR
Sources
AAffymetrix
EEST
IIn Situ
RRNA-Seq
data
no data
Rank scores
3.25e4lightgrey: low confidence scores

important score variation

Rank scores of expression calls are normalized across genes, conditions and species. Low score means that the gene is highly expressed in the condition. Max rank score in all species: 4.10e4. Min rank score varies across species.

Expression scores of expression calls use the minimum and maximum Rank of the species to normalize the expression to a value between 0 and 100. Low score means that the gene is lowly expressed in the condition.

Sources of annotations to anatomy and development:
  • RNA-Seq data: Bgee
Sources of raw data:

Orthologs

Taxon nameSpecies with orthologsGene(s)Expression comparisonSee details
Homininae2 species2 genesCompare expression
Catarrhini3 species3 genesCompare expression
Euarchontoglires5 species5 genesCompare expression
Boreoeutheria7 species7 genesCompare expression
Tetrapoda8 species8 genesCompare expression
Euteleostomi9 species9 genesCompare expression

Orthology information comes from OMA : ENSG00000125816.

Cross-references

CCDSCCDS42855 (CCDS42855.1)
EnsemblENSG00000125816 (NKX2-4)
HGNCHGNC:7837 (NKX2-4)
EMBLAF202037, AL158013, CH471133
OncoMXNKX2-4 (NKX2-4)
Uniprot/SWISSPROTNKX24_HUMAN, Q9H2Z4

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