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H. sapiens Gene: MTNR1B - ENSG00000134640 - Homo sapiens (human)

General information

Ensembl IDENSG00000134640
NameMTNR1B
Descriptionmelatonin receptor 1B [Source:HGNC Symbol;Acc:HGNC:7464]
OrganismHomo sapiens (human)
Synonym(s)fgqtl2, mel-1b-r, mt2
Orthologs(s)15 orthologs
Paralog(s)3 paralogs

Expression

Anat. entity IDAnatomical entityDevelopmental stage(s)Rank scoreExpression scoreSources
UBERON:0000006islet of Langerhans
  • HsapDv:000009025-44 year-old human stage (human)
  • HsapDv:0000092human middle aged stage (human)
  • HsapDv:000009465-79 year-old human stage (human)
1.62e4
  • 1.62e4
  • 1.98e4
  • 1.99e4
70.54
  • 70.54
  • 64.11
  • 63.85
AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0001882nucleus accumbens
  • HsapDv:0000088human early adulthood stage (human)
  • HsapDv:000009025-44 year-old human stage (human)
  • HsapDv:0000092human middle aged stage (human)
  • HsapDv:000009465-79 year-old human stage (human)
  • HsapDv:0000091human late adulthood stage (human)
  • HsapDv:0000087human adult stage (human)
1.88e4
  • 1.88e4
  • 2.14e4
  • 2.40e4
  • 2.53e4
  • 2.54e4
  • 2.79e4
65.87
  • 65.87
  • 61.23
  • 56.42
  • 54.06
  • 53.88
  • 49.29
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0001873caudate nucleus
  • HsapDv:0000088human early adulthood stage (human)
  • HsapDv:0000087human adult stage (human)
  • HsapDv:0000092human middle aged stage (human)
  • HsapDv:000009465-79 year-old human stage (human)
  • HsapDv:0000091human late adulthood stage (human)
1.93e4
  • 1.93e4
  • 2.71e4
  • 2.73e4
  • 2.74e4
  • 3.04e4
65.03
  • 65.03
  • 50.79
  • 50.38
  • 50.17
  • 44.79
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0000451prefrontal cortex
  • HsapDv:0000091human late adulthood stage (human)
  • HsapDv:0000086adolescent stage (human)
  • HsapDv:0000089young adult stage (human)
  • HsapDv:000009025-44 year-old human stage (human)
  • UBERON:0000104life cycle
2.12e4
  • 2.12e4
  • 3.37e4
  • 3.47e4
  • 3.80e4
  • 3.92e4
61.56
  • 61.56
  • 38.84
  • 37.06
  • 31.02
  • 28.88
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0004534right testis
  • HsapDv:000009025-44 year-old human stage (human)
  • HsapDv:0000088human early adulthood stage (human)
  • HsapDv:0000092human middle aged stage (human)
  • HsapDv:0000087human adult stage (human)
  • HsapDv:0000091human late adulthood stage (human)
2.50e4
  • 2.50e4
  • 2.85e4
  • 2.85e4
  • 2.86e4
  • 3.15e4
54.68
  • 54.68
  • 48.25
  • 48.22
  • 48.00
  • 42.73
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0000473testis
  • HsapDv:000009025-44 year-old human stage (human)
  • HsapDv:0000089young adult stage (human)
  • HsapDv:000009580 year-old and over human stage (human)
  • HsapDv:0000092human middle aged stage (human)
  • UBERON:0000113post-juvenile adult stage
  • UBERON:0000104life cycle
2.54e4
  • 2.54e4
  • 2.82e4
  • 2.85e4
  • 3.19e4
  • 3.21e4
  • 4.16e4
53.94
  • 53.94
  • 48.85
  • 48.21
  • 42.02
  • 41.80
  • 24.46
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0001987placenta
  • UBERON:0000113post-juvenile adult stage
2.61e4
  • 2.61e4
52.57
  • 52.57
AEIR
  • AEIR
UBERON:0004533left testis
  • HsapDv:000009465-79 year-old human stage (human)
  • HsapDv:0000091human late adulthood stage (human)
  • HsapDv:000009025-44 year-old human stage (human)
  • HsapDv:0000088human early adulthood stage (human)
  • HsapDv:0000092human middle aged stage (human)
  • HsapDv:0000087human adult stage (human)
2.63e4
  • 2.63e4
  • 2.80e4
  • 2.82e4
  • 2.85e4
  • 2.85e4
  • 3.03e4
52.23
  • 52.23
  • 49.14
  • 48.78
  • 48.19
  • 48.18
  • 45.01
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0001870frontal cortex
  • HsapDv:0000087human adult stage (human)
  • HsapDv:000009025-44 year-old human stage (human)
2.71e4
  • 2.71e4
  • 3.06e4
50.81
  • 50.81
  • 44.51
AEIR
  • AEIR
  • AEIR
UBERON:0002048lung
  • HsapDv:0000089young adult stage (human)
  • UBERON:0000113post-juvenile adult stage
2.84e4
  • 2.84e4
  • 4.30e4
48.35
  • 48.35
  • 21.89
AEIR
  • AEIR
  • AEIR
UBERON:0001898hypothalamus
  • HsapDv:0000087human adult stage (human)
  • HsapDv:0000092human middle aged stage (human)
  • HsapDv:0000091human late adulthood stage (human)
2.92e4
  • 2.92e4
  • 2.96e4
  • 3.37e4
47.02
  • 47.02
  • 46.22
  • 38.87
AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0009835anterior cingulate cortex
  • HsapDv:0000087human adult stage (human)
3.01e4
  • 3.01e4
45.27
  • 45.27
AEIR
  • AEIR
UBERON:0000945stomach
  • HsapDv:0000087human adult stage (human)
  • HsapDv:0000199fifth LMP month human stage (human)
  • UBERON:0000113post-juvenile adult stage
  • UBERON:0007220late embryonic stage
3.12e4
  • 3.12e4
  • 3.39e4
  • 4.41e4
  • 4.50e4
43.40
  • 43.40
  • 38.46
  • 19.96
  • 18.28
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0001876amygdala
  • HsapDv:0000087human adult stage (human)
  • HsapDv:0000092human middle aged stage (human)
  • HsapDv:0000091human late adulthood stage (human)
3.16e4
  • 3.16e4
  • 3.55e4
  • 3.77e4
42.71
  • 42.71
  • 35.61
  • 31.46
AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0001954Ammon's horn
  • HsapDv:000009465-79 year-old human stage (human)
  • HsapDv:0000092human middle aged stage (human)
  • HsapDv:0000087human adult stage (human)
  • HsapDv:0000091human late adulthood stage (human)
3.25e4
  • 3.25e4
  • 3.78e4
  • 4.07e4
  • 4.14e4
40.97
  • 40.97
  • 31.32
  • 26.16
  • 24.77
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0002107liver
  • HsapDv:0000092human middle aged stage (human)
  • HsapDv:0000087human adult stage (human)
  • UBERON:0000113post-juvenile adult stage
  • UBERON:0000104life cycle
3.27e4
  • 3.27e4
  • 3.51e4
  • 3.84e4
  • 4.10e4
40.56
  • 40.56
  • 36.32
  • 30.31
  • 25.54
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0009834dorsolateral prefrontal cortex
  • HsapDv:000009025-44 year-old human stage (human)
  • HsapDv:0000087human adult stage (human)
  • HsapDv:0000092human middle aged stage (human)
  • HsapDv:0000091human late adulthood stage (human)
  • HsapDv:0000088human early adulthood stage (human)
3.38e4
  • 3.38e4
  • 4.00e4
  • 4.09e4
  • 4.16e4
  • 4.64e4
38.55
  • 38.55
  • 27.35
  • 25.73
  • 24.50
  • 15.69
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0001874putamen
  • HsapDv:000009465-79 year-old human stage (human)
  • HsapDv:0000087human adult stage (human)
  • HsapDv:0000091human late adulthood stage (human)
  • HsapDv:0000092human middle aged stage (human)
3.40e4
  • 3.40e4
  • 3.55e4
  • 3.56e4
  • 3.61e4
38.30
  • 38.30
  • 35.50
  • 35.32
  • 34.46
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0013540Brodmann (1909) area 9
  • HsapDv:0000092human middle aged stage (human)
  • HsapDv:000009580 year-old and over human stage (human)
3.44e4
  • 3.44e4
  • 3.73e4
37.55
  • 37.55
  • 32.27
AEIR
  • AEIR
  • AEIR
UBERON:0001295endometrium
  • HsapDv:0000088human early adulthood stage (human)
  • UBERON:0000113post-juvenile adult stage
3.52e4
  • 3.52e4
  • 4.13e4
36.09
  • 36.09
  • 24.96
AEIR
  • AEIR
  • AEIR
UBERON:0006469C1 segment of cervical spinal cord
  • HsapDv:0000092human middle aged stage (human)
  • HsapDv:0000091human late adulthood stage (human)
  • HsapDv:0000087human adult stage (human)
3.58e4
  • 3.58e4
  • 3.80e4
  • 4.29e4
34.98
  • 34.98
  • 31.01
  • 22.05
AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0002038substantia nigra
  • HsapDv:0000092human middle aged stage (human)
  • HsapDv:0000091human late adulthood stage (human)
  • HsapDv:0000087human adult stage (human)
3.66e4
  • 3.66e4
  • 3.97e4
  • 4.28e4
33.59
  • 33.59
  • 27.99
  • 22.22
AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0001225cortex of kidney
  • UBERON:0000104life cycle
3.73e4
  • 3.73e4
32.34
  • 32.34
AEIR
  • AEIR
UBERON:0001255urinary bladder
  • UBERON:0000113post-juvenile adult stage
3.73e4
  • 3.73e4
32.20
  • 32.20
AEIR
  • AEIR
CL:0000576monocyte
  • UBERON:0000113post-juvenile adult stage
3.92e4
  • 3.92e4
28.91
  • 28.91
AEIR
  • AEIR
UBERON:0000029lymph node
  • UBERON:0000113post-juvenile adult stage
3.93e4
  • 3.93e4
28.55
  • 28.55
AEIR
  • AEIR
UBERON:0001013adipose tissue
  • UBERON:0000113post-juvenile adult stage
3.97e4
  • 3.97e4
27.88
  • 27.88
AEIR
  • AEIR
UBERON:0001161body of stomach
  • HsapDv:0000088human early adulthood stage (human)
  • HsapDv:0000087human adult stage (human)
3.98e4
  • 3.98e4
  • 4.38e4
27.76
  • 27.76
  • 20.49
AEIR
  • AEIR
  • AEIR
UBERON:0001416skin of abdomen
  • HsapDv:0000087human adult stage (human)
  • HsapDv:0000092human middle aged stage (human)
  • HsapDv:0000091human late adulthood stage (human)
3.98e4
  • 3.98e4
  • 4.02e4
  • 4.18e4
27.75
  • 27.75
  • 27.06
  • 24.04
AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0001511skin of leg
  • HsapDv:0000092human middle aged stage (human)
  • HsapDv:0000091human late adulthood stage (human)
  • HsapDv:0000087human adult stage (human)
4.01e4
  • 4.01e4
  • 4.12e4
  • 4.21e4
27.15
  • 27.15
  • 25.24
  • 23.48
AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0002810right frontal lobe
  • HsapDv:0000087human adult stage (human)
4.03e4
  • 4.03e4
26.78
  • 26.78
AEIR
  • AEIR
UBERON:0002046thyroid gland
  • UBERON:0000113post-juvenile adult stage
  • HsapDv:0000091human late adulthood stage (human)
  • HsapDv:0000087human adult stage (human)
4.28e4
  • 4.28e4
  • 4.45e4
  • 4.59e4
22.23
  • 22.23
  • 19.26
  • 16.72
AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0007610tibial artery
  • HsapDv:0000087human adult stage (human)
  • HsapDv:0000091human late adulthood stage (human)
4.49e4
  • 4.49e4
  • 4.50e4
18.38
  • 18.38
  • 18.34
AEIR
  • AEIR
  • AEIR
UBERON:0001120left lobe of thyroid gland
  • HsapDv:0000091human late adulthood stage (human)
  • HsapDv:0000087human adult stage (human)
4.54e4
  • 4.54e4
  • 4.59e4
17.64
  • 17.64
  • 16.70
AEIR
  • AEIR
  • AEIR
UBERON:0001323tibial nerve
  • HsapDv:0000087human adult stage (human)
  • HsapDv:0000091human late adulthood stage (human)
4.57e4
  • 4.57e4
  • 4.61e4
17.07
  • 17.07
  • 16.28
AEIR
  • AEIR
  • AEIR
UBERON:0000007pituitary gland
  • HsapDv:0000091human late adulthood stage (human)
  • HsapDv:0000092human middle aged stage (human)
  • HsapDv:0000087human adult stage (human)
4.60e4
  • 4.60e4
  • 4.62e4
  • 4.80e4
16.48
  • 16.48
  • 16.20
  • 12.83
AEIR
  • AEIR
  • AEIR
  • AEIR
Sources
AAffymetrix
EEST
IIn Situ
RRNA-Seq
data
no data
Rank scores
3.25e4lightgrey: low confidence scores

important score variation

Rank scores of expression calls are normalized across genes, conditions and species. Low score means that the gene is highly expressed in the condition. Max rank score in all species: 4.10e4. Min rank score varies across species.

Expression scores of expression calls use the minimum and maximum Rank of the species to normalize the expression to a value between 0 and 100. Low score means that the gene is lowly expressed in the condition.

Sources of annotations to anatomy and development:
  • RNA-Seq data: Bgee
Sources of raw data:

Orthologs

Taxon nameSpecies with orthologsGene(s)Expression comparisonSee details
Homininae2 species2 genesCompare expression
Catarrhini3 species3 genesCompare expression
Euarchontoglires7 species7 genesCompare expression
Boreoeutheria11 species11 genesCompare expression
Theria12 species12 genesCompare expression
Amniota14 species14 genesCompare expression
Tetrapoda15 species15 genesCompare expression

Orthology information comes from OMA : ENSG00000134640.

Paralogs (same species)

Taxon nameGene(s)Expression comparisonSee details
Deuterostomia1 geneCompare expression
Eumetazoa3 genesCompare expression

Paralogy information comes from OMA : ENSG00000134640.

Cross-references

CCDSCCDS8290 (CCDS8290.1)
EnsemblENSG00000134640 (MTNR1B)
HGNCHGNC:7464 (MTNR1B)
EMBLAB033598, AP002371, AP003171, AY521019, BC069163, U25341
OncoMXMTNR1B (MTNR1B)
Uniprot/SPTREMBLE9PR36, E9PR36_HUMAN, H0YDG4, H0YDG4_HUMAN
Uniprot/SWISSPROTMTR1B_HUMAN, P49286

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