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H. sapiens Gene: GPR45 - ENSG00000135973 - Homo sapiens (human)

General information

Ensembl IDENSG00000135973
NameGPR45
DescriptionG protein-coupled receptor 45 [Source:HGNC Symbol;Acc:HGNC:4503]
OrganismHomo sapiens (human)
Synonym(s)psp24, psp24(alpha), psp24a, q6nws4, q6nxu6
Orthologs(s)15 orthologs
Paralog(s)1 paralogs

Expression

Anat. entity IDAnatomical entityDevelopmental stage(s)Rank scoreExpression scoreSources
UBERON:0005343cortical plate
  • HsapDv:0000199fifth LMP month human stage (human)
  • HsapDv:0000198fourth LMP month human stage (human)
1.44e4
  • 1.44e4
  • 1.72e4
73.84
  • 73.84
  • 68.80
AEIR
  • AEIR
  • AEIR
UBERON:0009834dorsolateral prefrontal cortex
  • HsapDv:0000089young adult stage (human)
  • HsapDv:0000088human early adulthood stage (human)
  • HsapDv:000009025-44 year-old human stage (human)
  • HsapDv:0000087human adult stage (human)
  • HsapDv:0000092human middle aged stage (human)
  • HsapDv:000009465-79 year-old human stage (human)
  • HsapDv:0000091human late adulthood stage (human)
1.56e4
  • 1.56e4
  • 1.78e4
  • 1.78e4
  • 1.86e4
  • 1.96e4
  • 2.11e4
  • 2.11e4
71.60
  • 71.60
  • 67.73
  • 67.63
  • 66.24
  • 64.39
  • 61.70
  • 61.62
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0000451prefrontal cortex
  • HsapDv:0000089young adult stage (human)
  • HsapDv:000009025-44 year-old human stage (human)
  • HsapDv:0000086adolescent stage (human)
  • HsapDv:000009465-79 year-old human stage (human)
  • HsapDv:0000092human middle aged stage (human)
  • HsapDv:0000091human late adulthood stage (human)
  • UBERON:0000104life cycle
1.59e4
  • 1.59e4
  • 1.66e4
  • 1.74e4
  • 1.77e4
  • 1.84e4
  • 1.86e4
  • 1.93e4
71.05
  • 71.05
  • 69.87
  • 68.47
  • 67.94
  • 66.65
  • 66.18
  • 64.87
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0009835anterior cingulate cortex
  • HsapDv:000009025-44 year-old human stage (human)
  • HsapDv:0000088human early adulthood stage (human)
  • HsapDv:0000087human adult stage (human)
  • HsapDv:0000092human middle aged stage (human)
  • HsapDv:0000091human late adulthood stage (human)
  • HsapDv:000009465-79 year-old human stage (human)
1.61e4
  • 1.61e4
  • 1.86e4
  • 1.92e4
  • 2.01e4
  • 2.18e4
  • 2.21e4
70.69
  • 70.69
  • 66.29
  • 65.16
  • 63.53
  • 60.48
  • 59.92
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0001876amygdala
  • HsapDv:000009025-44 year-old human stage (human)
  • HsapDv:0000087human adult stage (human)
  • HsapDv:0000092human middle aged stage (human)
  • HsapDv:0000091human late adulthood stage (human)
  • HsapDv:000009465-79 year-old human stage (human)
1.64e4
  • 1.64e4
  • 1.94e4
  • 2.15e4
  • 2.17e4
  • 2.63e4
70.30
  • 70.30
  • 64.72
  • 60.90
  • 60.59
  • 52.20
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0002810right frontal lobe
  • HsapDv:0000088human early adulthood stage (human)
  • HsapDv:000009025-44 year-old human stage (human)
  • HsapDv:0000087human adult stage (human)
  • HsapDv:0000092human middle aged stage (human)
  • HsapDv:0000091human late adulthood stage (human)
1.65e4
  • 1.65e4
  • 1.67e4
  • 1.92e4
  • 1.94e4
  • 2.21e4
70.00
  • 70.00
  • 69.72
  • 65.06
  • 64.77
  • 59.86
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0001871temporal lobe
  • HsapDv:0000089young adult stage (human)
1.70e4
  • 1.70e4
69.20
  • 69.20
AEIR
  • AEIR
UBERON:0002661superior frontal gyrus
  • UBERON:0000104life cycle
1.70e4
  • 1.70e4
69.15
  • 69.15
AEIR
  • AEIR
UBERON:0001898hypothalamus
  • HsapDv:0000087human adult stage (human)
  • HsapDv:0000092human middle aged stage (human)
  • HsapDv:000009465-79 year-old human stage (human)
  • HsapDv:0000091human late adulthood stage (human)
  • HsapDv:000009025-44 year-old human stage (human)
1.72e4
  • 1.72e4
  • 1.91e4
  • 2.04e4
  • 2.09e4
  • 2.26e4
68.84
  • 68.84
  • 65.29
  • 62.96
  • 62.09
  • 58.97
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
PBA:294021980subventricular zone (outer) (primate)
  • HsapDv:0000199fifth LMP month human stage (human)
1.76e4
  • 1.76e4
67.99
  • 67.99
AEIR
  • AEIR
UBERON:0001870frontal cortex
  • HsapDv:0000092human middle aged stage (human)
  • HsapDv:000009025-44 year-old human stage (human)
  • UBERON:0034920infant stage
  • HsapDv:0000087human adult stage (human)
1.77e4
  • 1.77e4
  • 1.82e4
  • 1.85e4
  • 2.42e4
67.82
  • 67.82
  • 67.02
  • 66.43
  • 56.03
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0001954Ammon's horn
  • HsapDv:000009025-44 year-old human stage (human)
  • HsapDv:0000092human middle aged stage (human)
  • HsapDv:000009465-79 year-old human stage (human)
  • HsapDv:0000091human late adulthood stage (human)
  • HsapDv:0000087human adult stage (human)
1.79e4
  • 1.79e4
  • 2.15e4
  • 2.22e4
  • 2.25e4
  • 2.30e4
67.49
  • 67.49
  • 61.02
  • 59.68
  • 59.10
  • 58.18
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0001873caudate nucleus
  • HsapDv:0000088human early adulthood stage (human)
  • HsapDv:000009025-44 year-old human stage (human)
  • HsapDv:0000087human adult stage (human)
  • HsapDv:0000092human middle aged stage (human)
  • HsapDv:000009465-79 year-old human stage (human)
  • HsapDv:0000091human late adulthood stage (human)
1.83e4
  • 1.83e4
  • 1.95e4
  • 2.02e4
  • 2.09e4
  • 2.21e4
  • 2.24e4
66.84
  • 66.84
  • 64.54
  • 63.33
  • 62.02
  • 59.94
  • 59.31
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0013540Brodmann (1909) area 9
  • HsapDv:000009025-44 year-old human stage (human)
  • HsapDv:0000092human middle aged stage (human)
  • HsapDv:000009580 year-old and over human stage (human)
  • HsapDv:000009465-79 year-old human stage (human)
1.86e4
  • 1.86e4
  • 1.90e4
  • 2.14e4
  • 2.20e4
66.15
  • 66.15
  • 65.53
  • 61.09
  • 60.13
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0002038substantia nigra
  • HsapDv:0000088human early adulthood stage (human)
  • HsapDv:0000092human middle aged stage (human)
  • HsapDv:0000087human adult stage (human)
  • HsapDv:000009025-44 year-old human stage (human)
  • HsapDv:000009465-79 year-old human stage (human)
  • HsapDv:0000091human late adulthood stage (human)
1.89e4
  • 1.89e4
  • 2.16e4
  • 2.19e4
  • 2.23e4
  • 2.23e4
  • 2.25e4
65.62
  • 65.62
  • 60.83
  • 60.27
  • 59.60
  • 59.57
  • 59.20
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0001882nucleus accumbens
  • HsapDv:0000087human adult stage (human)
  • HsapDv:0000092human middle aged stage (human)
  • HsapDv:000009025-44 year-old human stage (human)
  • HsapDv:0000088human early adulthood stage (human)
  • HsapDv:0000091human late adulthood stage (human)
  • HsapDv:000009465-79 year-old human stage (human)
2.00e4
  • 2.00e4
  • 2.04e4
  • 2.07e4
  • 2.12e4
  • 2.25e4
  • 2.28e4
63.74
  • 63.74
  • 62.92
  • 62.41
  • 61.60
  • 59.10
  • 58.65
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0001874putamen
  • HsapDv:0000087human adult stage (human)
  • HsapDv:000009025-44 year-old human stage (human)
  • HsapDv:0000092human middle aged stage (human)
  • HsapDv:0000091human late adulthood stage (human)
2.09e4
  • 2.09e4
  • 2.17e4
  • 2.17e4
  • 2.21e4
61.98
  • 61.98
  • 60.69
  • 60.51
  • 59.94
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0006469C1 segment of cervical spinal cord
  • HsapDv:000009025-44 year-old human stage (human)
  • HsapDv:0000087human adult stage (human)
  • HsapDv:0000092human middle aged stage (human)
  • HsapDv:0000088human early adulthood stage (human)
  • HsapDv:0000091human late adulthood stage (human)
2.19e4
  • 2.19e4
  • 2.42e4
  • 2.66e4
  • 2.78e4
  • 2.91e4
60.28
  • 60.28
  • 56.05
  • 51.79
  • 49.49
  • 47.22
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0002436primary visual cortex
  • UBERON:0000104life cycle
2.40e4
  • 2.40e4
56.50
  • 56.50
AEIR
  • AEIR
PBA:294022000subventricular zone (inner) (primate)
  • HsapDv:0000199fifth LMP month human stage (human)
  • HsapDv:0000198fourth LMP month human stage (human)
2.43e4
  • 2.43e4
  • 2.52e4
55.94
  • 55.94
  • 54.21
AEIR
  • AEIR
  • AEIR
UBERON:0002037cerebellum
  • UBERON:0000104life cycle
2.48e4
  • 2.48e4
54.99
  • 54.99
AEIR
  • AEIR
UBERON:0000473testis
  • HsapDv:000009025-44 year-old human stage (human)
  • UBERON:0000113post-juvenile adult stage
  • HsapDv:0000092human middle aged stage (human)
  • UBERON:0000104life cycle
2.54e4
  • 2.54e4
  • 3.30e4
  • 3.30e4
  • 4.16e4
53.88
  • 53.88
  • 40.13
  • 40.11
  • 24.46
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0001043esophagus
  • HsapDv:0000092human middle aged stage (human)
  • HsapDv:0000087human adult stage (human)
  • UBERON:0000113post-juvenile adult stage
2.72e4
  • 2.72e4
  • 2.73e4
  • 3.61e4
50.68
  • 50.68
  • 50.44
  • 34.48
AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0004533left testis
  • HsapDv:0000088human early adulthood stage (human)
  • HsapDv:000009025-44 year-old human stage (human)
  • HsapDv:0000092human middle aged stage (human)
  • HsapDv:000009465-79 year-old human stage (human)
  • HsapDv:0000091human late adulthood stage (human)
  • HsapDv:0000087human adult stage (human)
2.77e4
  • 2.77e4
  • 2.82e4
  • 2.82e4
  • 2.86e4
  • 2.93e4
  • 2.97e4
49.71
  • 49.71
  • 48.79
  • 48.78
  • 48.04
  • 46.81
  • 46.11
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0002129cerebellar cortex
  • UBERON:0000104life cycle
2.84e4
  • 2.84e4
48.40
  • 48.40
AEIR
  • AEIR
UBERON:0001120left lobe of thyroid gland
  • HsapDv:0000087human adult stage (human)
  • HsapDv:0000092human middle aged stage (human)
  • HsapDv:0000091human late adulthood stage (human)
2.85e4
  • 2.85e4
  • 2.98e4
  • 3.05e4
48.32
  • 48.32
  • 45.93
  • 44.53
AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0004534right testis
  • HsapDv:0000087human adult stage (human)
  • HsapDv:0000092human middle aged stage (human)
  • HsapDv:0000091human late adulthood stage (human)
2.89e4
  • 2.89e4
  • 2.92e4
  • 3.32e4
47.50
  • 47.50
  • 46.92
  • 39.66
AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0001161body of stomach
  • HsapDv:0000087human adult stage (human)
  • HsapDv:0000092human middle aged stage (human)
  • HsapDv:0000091human late adulthood stage (human)
2.89e4
  • 2.89e4
  • 2.95e4
  • 3.08e4
47.49
  • 47.49
  • 46.50
  • 44.03
AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0002469esophagus mucosa
  • HsapDv:0000092human middle aged stage (human)
  • HsapDv:0000087human adult stage (human)
  • HsapDv:0000091human late adulthood stage (human)
2.99e4
  • 2.99e4
  • 3.02e4
  • 3.06e4
45.62
  • 45.62
  • 45.20
  • 44.49
AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0001987placenta
  • UBERON:0000113post-juvenile adult stage
3.00e4
  • 3.00e4
45.60
  • 45.60
AEIR
  • AEIR
UBERON:0014890right hemisphere of cerebellum
  • HsapDv:0000087human adult stage (human)
  • HsapDv:0000091human late adulthood stage (human)
  • HsapDv:0000092human middle aged stage (human)
3.01e4
  • 3.01e4
  • 3.04e4
  • 3.07e4
45.30
  • 45.30
  • 44.75
  • 44.31
AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0001157transverse colon
  • HsapDv:0000087human adult stage (human)
3.03e4
  • 3.03e4
44.92
  • 44.92
AEIR
  • AEIR
UBERON:0010414omental fat pad
  • HsapDv:0000092human middle aged stage (human)
  • HsapDv:0000087human adult stage (human)
  • HsapDv:0000091human late adulthood stage (human)
  • HsapDv:000009465-79 year-old human stage (human)
3.14e4
  • 3.14e4
  • 3.20e4
  • 3.41e4
  • 3.77e4
43.06
  • 43.06
  • 41.85
  • 38.14
  • 31.50
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
CL:0000576monocyte
  • UBERON:0000113post-juvenile adult stage
3.15e4
  • 3.15e4
42.77
  • 42.77
AEIR
  • AEIR
UBERON:0001296myometrium
  • HsapDv:0000091human late adulthood stage (human)
  • HsapDv:0000087human adult stage (human)
3.28e4
  • 3.28e4
  • 3.81e4
40.39
  • 40.39
  • 30.86
AEIR
  • AEIR
  • AEIR
UBERON:0006631right atrium auricular region
  • HsapDv:0000087human adult stage (human)
3.45e4
  • 3.45e4
37.43
  • 37.43
AEIR
  • AEIR
UBERON:0000014zone of skin
  • UBERON:0000113post-juvenile adult stage
3.45e4
  • 3.45e4
37.39
  • 37.39
AEIR
  • AEIR
UBERON:0000178blood
  • UBERON:0000113post-juvenile adult stage
  • HsapDv:0000087human adult stage (human)
  • HsapDv:0000091human late adulthood stage (human)
  • UBERON:0000104life cycle
3.58e4
  • 3.58e4
  • 3.88e4
  • 3.97e4
  • 4.06e4
35.06
  • 35.06
  • 29.50
  • 27.92
  • 26.26
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0007610tibial artery
  • HsapDv:0000087human adult stage (human)
  • HsapDv:0000091human late adulthood stage (human)
3.58e4
  • 3.58e4
  • 3.80e4
35.05
  • 35.05
  • 30.91
AEIR
  • AEIR
  • AEIR
UBERON:0001295endometrium
  • HsapDv:0000088human early adulthood stage (human)
  • UBERON:0000113post-juvenile adult stage
3.61e4
  • 3.61e4
  • 4.32e4
34.54
  • 34.54
  • 21.54
AEIR
  • AEIR
  • AEIR
UBERON:0001383muscle of leg
  • HsapDv:0000088human early adulthood stage (human)
3.67e4
  • 3.67e4
33.32
  • 33.32
AEIR
  • AEIR
UBERON:0000006islet of Langerhans
  • HsapDv:0000092human middle aged stage (human)
3.71e4
  • 3.71e4
32.58
  • 32.58
AEIR
  • AEIR
UBERON:0002108small intestine
  • UBERON:0000113post-juvenile adult stage
3.77e4
  • 3.77e4
31.63
  • 31.63
AEIR
  • AEIR
UBERON:0001255urinary bladder
  • UBERON:0000113post-juvenile adult stage
3.86e4
  • 3.86e4
29.93
  • 29.93
AEIR
  • AEIR
UBERON:0001511skin of leg
  • HsapDv:0000087human adult stage (human)
4.01e4
  • 4.01e4
27.10
  • 27.10
AEIR
  • AEIR
Sources
AAffymetrix
EEST
IIn Situ
RRNA-Seq
data
no data
Rank scores
3.25e4lightgrey: low confidence scores

important score variation

Rank scores of expression calls are normalized across genes, conditions and species. Low score means that the gene is highly expressed in the condition. Max rank score in all species: 4.10e4. Min rank score varies across species.

Expression scores of expression calls use the minimum and maximum Rank of the species to normalize the expression to a value between 0 and 100. Low score means that the gene is lowly expressed in the condition.

Sources of annotations to anatomy and development:
  • RNA-Seq data: Bgee
Sources of raw data:

Orthologs

Taxon nameSpecies with orthologsGene(s)Expression comparisonSee details
Homininae1 species1 geneCompare expression
Catarrhini2 species2 genesCompare expression
Euarchontoglires6 species6 genesCompare expression
Boreoeutheria11 species11 genesCompare expression
Theria12 species12 genesCompare expression
Amniota13 species13 genesCompare expression
Tetrapoda14 species14 genesCompare expression
Euteleostomi15 species15 genesCompare expression

Orthology information comes from OMA : ENSG00000135973.

Paralogs (same species)

Taxon nameGene(s)Expression comparisonSee details
Chordata1 geneCompare expression

Paralogy information comes from OMA : ENSG00000135973.

Cross-references

CCDSCCDS2066 (CCDS2066.1)
EnsemblENSG00000135973 (GPR45)
HGNCHGNC:4503 (GPR45)
EMBLAC012360, AF118266, BC066879, BC066880, BC067455, CH471127, EU883573
OncoMXGPR45 (GPR45)
Uniprot/SPTREMBLB5B0C1, B5B0C1_HUMAN
Uniprot/SWISSPROTGPR45_HUMAN, Q9Y5Y3

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