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H. sapiens Gene: C8A - ENSG00000157131 - Homo sapiens (human)

General information

Ensembl IDENSG00000157131
NameC8A
Descriptioncomplement component 8, alpha polypeptide [Source:HGNC Symbol;Acc:HGNC:1352]
OrganismHomo sapiens (human)
Synonym(s)a2rui4, a2rui5, q13668, q9h130
Orthologs(s)19 orthologs

Expression

Anat. entity IDAnatomical entityDevelopmental stage(s)Rank scoreExpression scoreSources
UBERON:0001114right lobe of liver
  • HsapDv:000009025-44 year-old human stage (human)
  • HsapDv:0000087human adult stage (human)
  • HsapDv:0000092human middle aged stage (human)
  • HsapDv:0000091human late adulthood stage (human)
  • HsapDv:0000088human early adulthood stage (human)
403
  • 403
  • 460
  • 485
  • 532
  • 587
99.27
  • 99.27
  • 99.17
  • 99.12
  • 99.04
  • 98.94
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0002107liver
  • HsapDv:00000842-5 year-old child stage (human)
  • HsapDv:0000087human adult stage (human)
  • UBERON:0000113post-juvenile adult stage
  • HsapDv:000009465-79 year-old human stage (human)
  • UBERON:0000104life cycle
  • HsapDv:0000092human middle aged stage (human)
  • UBERON:0034920infant stage
  • HsapDv:00000856-12 year-old child stage (human)
  • HsapDv:000009580 year-old and over human stage (human)
  • HsapDv:000009025-44 year-old human stage (human)
  • HsapDv:0000089young adult stage (human)
  • UBERON:0000111organogenesis stage
  • HsapDv:0000197third LMP month human stage (human)
  • UBERON:0007220late embryonic stage
411
  • 411
  • 470
  • 484
  • 534
  • 534
  • 546
  • 567
  • 581
  • 650
  • 741
  • 1.25e3
  • 3.45e3
  • 3.78e3
  • 7.39e3
99.25
  • 99.25
  • 99.15
  • 99.12
  • 99.03
  • 99.03
  • 99.01
  • 98.97
  • 98.95
  • 98.82
  • 98.66
  • 97.73
  • 93.74
  • 93.15
  • 86.58
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0000160intestine
  • UBERON:0000104life cycle
  • HsapDv:0000199fifth LMP month human stage (human)
8.30e3
  • 8.30e3
  • 2.41e4
84.94
  • 84.94
  • 56.33
AEIR
  • AEIR
  • AEIR
CL:0002336buccal mucosa cell
  • HsapDv:000009025-44 year-old human stage (human)
8.62e3
  • 8.62e3
84.36
  • 84.36
AEIR
  • AEIR
UBERON:0002110gall bladder
  • UBERON:0000113post-juvenile adult stage
  • HsapDv:0000087human adult stage (human)
  • UBERON:0000104life cycle
1.40e4
  • 1.40e4
  • 2.33e4
  • 2.75e4
74.50
  • 74.50
  • 57.68
  • 50.00
AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0002114duodenum
  • UBERON:0000113post-juvenile adult stage
  • UBERON:0000104life cycle
1.76e4
  • 1.76e4
  • 3.23e4
68.11
  • 68.11
  • 41.27
AEIR
  • AEIR
  • AEIR
UBERON:0000945stomach
  • HsapDv:0000197third LMP month human stage (human)
  • UBERON:0000113post-juvenile adult stage
  • UBERON:0000104life cycle
  • UBERON:0007220late embryonic stage
  • HsapDv:0000199fifth LMP month human stage (human)
  • HsapDv:0000087human adult stage (human)
  • HsapDv:000009025-44 year-old human stage (human)
  • HsapDv:0000092human middle aged stage (human)
1.94e4
  • 1.94e4
  • 2.54e4
  • 2.75e4
  • 2.87e4
  • 3.10e4
  • 3.98e4
  • 4.08e4
  • 4.73e4
64.83
  • 64.83
  • 53.84
  • 50.02
  • 47.87
  • 43.79
  • 27.68
  • 25.92
  • 14.10
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0018303adrenal tissue
  • HsapDv:0000197third LMP month human stage (human)
  • HsapDv:0000199fifth LMP month human stage (human)
2.10e4
  • 2.10e4
  • 2.70e4
61.90
  • 61.90
  • 50.99
AEIR
  • AEIR
  • AEIR
UBERON:0002048lung
  • HsapDv:0000091human late adulthood stage (human)
  • UBERON:0007220late embryonic stage
  • HsapDv:0000087human adult stage (human)
  • UBERON:0000104life cycle
  • HsapDv:000009025-44 year-old human stage (human)
  • UBERON:0000113post-juvenile adult stage
2.23e4
  • 2.23e4
  • 2.78e4
  • 2.88e4
  • 3.02e4
  • 3.50e4
  • 3.79e4
59.46
  • 59.46
  • 49.49
  • 47.73
  • 45.10
  • 36.51
  • 31.21
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0000082adult mammalian kidney
  • HsapDv:0000087human adult stage (human)
  • HsapDv:0000092human middle aged stage (human)
  • HsapDv:0000091human late adulthood stage (human)
  • UBERON:0000113post-juvenile adult stage
2.34e4
  • 2.34e4
  • 2.84e4
  • 3.29e4
  • 4.38e4
57.52
  • 57.52
  • 48.36
  • 40.23
  • 20.39
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0000948heart
  • UBERON:0000104life cycle
  • UBERON:0000113post-juvenile adult stage
  • HsapDv:0000092human middle aged stage (human)
2.35e4
  • 2.35e4
  • 4.14e4
  • 4.19e4
57.27
  • 57.27
  • 24.75
  • 23.90
AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0000995uterus
  • HsapDv:0000087human adult stage (human)
  • UBERON:0000104life cycle
2.39e4
  • 2.39e4
  • 2.70e4
56.57
  • 56.57
  • 50.95
AEIR
  • AEIR
  • AEIR
UBERON:0000399jejunal mucosa
  • UBERON:0000104life cycle
2.48e4
  • 2.48e4
54.90
  • 54.90
AEIR
  • AEIR
UBERON:0001160fundus of stomach
  • HsapDv:000009025-44 year-old human stage (human)
  • HsapDv:0000088human early adulthood stage (human)
  • HsapDv:0000087human adult stage (human)
2.49e4
  • 2.49e4
  • 3.77e4
  • 4.75e4
54.74
  • 54.74
  • 31.56
  • 13.69
AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0008952upper lobe of left lung
  • HsapDv:000009025-44 year-old human stage (human)
  • HsapDv:0000088human early adulthood stage (human)
  • HsapDv:0000091human late adulthood stage (human)
  • HsapDv:0000087human adult stage (human)
2.52e4
  • 2.52e4
  • 2.75e4
  • 3.03e4
  • 3.15e4
54.25
  • 54.25
  • 50.08
  • 44.91
  • 42.89
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0002031epithelium of bronchus
  • HsapDv:000009025-44 year-old human stage (human)
  • UBERON:0000104life cycle
  • HsapDv:0000088human early adulthood stage (human)
2.57e4
  • 2.57e4
  • 2.68e4
  • 2.77e4
53.32
  • 53.32
  • 51.40
  • 49.62
AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0000955brain
  • UBERON:0000104life cycle
  • HsapDv:0000089young adult stage (human)
  • HsapDv:0000087human adult stage (human)
2.58e4
  • 2.58e4
  • 3.07e4
  • 4.17e4
53.15
  • 53.15
  • 44.29
  • 24.32
AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0001987placenta
  • UBERON:0000111organogenesis stage
  • UBERON:0000104life cycle
  • UBERON:0000068embryo stage
2.62e4
  • 2.62e4
  • 2.80e4
  • 3.15e4
52.39
  • 52.39
  • 49.12
  • 42.89
AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0000006islet of Langerhans
  • HsapDv:000009025-44 year-old human stage (human)
  • UBERON:0000104life cycle
  • HsapDv:0000092human middle aged stage (human)
  • HsapDv:000009465-79 year-old human stage (human)
2.64e4
  • 2.64e4
  • 2.73e4
  • 2.81e4
  • 2.84e4
52.12
  • 52.12
  • 50.49
  • 49.07
  • 48.49
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0000014zone of skin
  • HsapDv:000009025-44 year-old human stage (human)
  • HsapDv:0000087human adult stage (human)
  • UBERON:0000104life cycle
  • HsapDv:0000092human middle aged stage (human)
  • UBERON:0000113post-juvenile adult stage
2.64e4
  • 2.64e4
  • 3.08e4
  • 3.12e4
  • 3.24e4
  • 4.00e4
52.06
  • 52.06
  • 44.10
  • 43.41
  • 41.13
  • 27.31
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0000956cerebral cortex
  • UBERON:0000104life cycle
  • HsapDv:0000089young adult stage (human)
  • UBERON:0000113post-juvenile adult stage
2.70e4
  • 2.70e4
  • 3.22e4
  • 4.49e4
51.02
  • 51.02
  • 41.45
  • 18.51
AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0001954Ammon's horn
  • UBERON:0000104life cycle
  • HsapDv:0000087human adult stage (human)
  • HsapDv:0000091human late adulthood stage (human)
2.80e4
  • 2.80e4
  • 4.10e4
  • 4.14e4
49.17
  • 49.17
  • 25.50
  • 24.82
AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0002106spleen
  • UBERON:0000104life cycle
  • HsapDv:0000087human adult stage (human)
  • HsapDv:0000092human middle aged stage (human)
  • HsapDv:0000091human late adulthood stage (human)
  • UBERON:0000113post-juvenile adult stage
2.83e4
  • 2.83e4
  • 3.60e4
  • 3.65e4
  • 3.85e4
  • 4.15e4
48.66
  • 48.66
  • 34.70
  • 33.73
  • 30.11
  • 24.61
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0001388gastrocnemius
  • UBERON:0000104life cycle
  • HsapDv:0000087human adult stage (human)
  • HsapDv:0000091human late adulthood stage (human)
  • HsapDv:0000092human middle aged stage (human)
2.86e4
  • 2.86e4
  • 3.74e4
  • 3.75e4
  • 3.88e4
48.03
  • 48.03
  • 32.04
  • 31.84
  • 29.48
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0001155colon
  • HsapDv:0000087human adult stage (human)
  • UBERON:0000104life cycle
  • UBERON:0000113post-juvenile adult stage
2.87e4
  • 2.87e4
  • 3.10e4
  • 4.26e4
47.87
  • 47.87
  • 43.80
  • 22.65
AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0001893telencephalon
  • HsapDv:0000087human adult stage (human)
2.90e4
  • 2.90e4
47.32
  • 47.32
AEIR
  • AEIR
UBERON:0000947aorta
  • UBERON:0000104life cycle
2.91e4
  • 2.91e4
47.13
  • 47.13
AEIR
  • AEIR
UBERON:0001161body of stomach
  • HsapDv:0000091human late adulthood stage (human)
  • HsapDv:0000087human adult stage (human)
  • HsapDv:0000092human middle aged stage (human)
  • HsapDv:0000088human early adulthood stage (human)
2.95e4
  • 2.95e4
  • 3.06e4
  • 3.33e4
  • 3.36e4
46.38
  • 46.38
  • 44.39
  • 39.61
  • 38.91
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0004804oviduct epithelium
  • HsapDv:000009025-44 year-old human stage (human)
2.96e4
  • 2.96e4
46.28
  • 46.28
AEIR
  • AEIR
UBERON:0001044saliva-secreting gland
  • UBERON:0000104life cycle
  • UBERON:0000113post-juvenile adult stage
2.96e4
  • 2.96e4
  • 4.20e4
46.18
  • 46.18
  • 23.68
AEIR
  • AEIR
  • AEIR
UBERON:0000178blood
  • HsapDv:000009465-79 year-old human stage (human)
  • HsapDv:0000091human late adulthood stage (human)
  • HsapDv:000009025-44 year-old human stage (human)
  • HsapDv:0000092human middle aged stage (human)
  • UBERON:0000104life cycle
  • HsapDv:0000087human adult stage (human)
  • UBERON:0000113post-juvenile adult stage
  • HsapDv:0000088human early adulthood stage (human)
2.97e4
  • 2.97e4
  • 3.30e4
  • 3.32e4
  • 3.33e4
  • 3.38e4
  • 3.45e4
  • 3.74e4
  • 3.90e4
46.14
  • 46.14
  • 40.12
  • 39.78
  • 39.58
  • 38.71
  • 37.31
  • 32.01
  • 29.13
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0001150body of pancreas
  • HsapDv:0000087human adult stage (human)
  • HsapDv:0000088human early adulthood stage (human)
3.03e4
  • 3.03e4
  • 3.21e4
44.95
  • 44.95
  • 41.67
AEIR
  • AEIR
  • AEIR
UBERON:0002384connective tissue
  • UBERON:0000104life cycle
3.04e4
  • 3.04e4
44.86
  • 44.86
AEIR
  • AEIR
UBERON:0001013adipose tissue
  • HsapDv:000009025-44 year-old human stage (human)
  • HsapDv:0000092human middle aged stage (human)
  • UBERON:0000104life cycle
  • UBERON:0000113post-juvenile adult stage
3.07e4
  • 3.07e4
  • 3.14e4
  • 3.16e4
  • 4.05e4
44.29
  • 44.29
  • 43.01
  • 42.64
  • 26.40
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0007808adipose tissue of abdominal region
  • HsapDv:0000092human middle aged stage (human)
  • HsapDv:000009025-44 year-old human stage (human)
  • HsapDv:0000088human early adulthood stage (human)
3.12e4
  • 3.12e4
  • 3.17e4
  • 3.22e4
43.31
  • 43.31
  • 42.40
  • 41.59
AEIR
  • AEIR
  • AEIR
  • AEIR
CL:0002328bronchial epithelial cell
  • HsapDv:000009025-44 year-old human stage (human)
3.16e4
  • 3.16e4
42.64
  • 42.64
AEIR
  • AEIR
UBERON:0003729mouth mucosa
  • UBERON:0000104life cycle
3.17e4
  • 3.17e4
42.39
  • 42.39
AEIR
  • AEIR
UBERON:0002367prostate gland
  • UBERON:0000104life cycle
3.18e4
  • 3.18e4
42.18
  • 42.18
AEIR
  • AEIR
UBERON:0001295endometrium
  • UBERON:0000104life cycle
  • HsapDv:0000088human early adulthood stage (human)
  • UBERON:0000113post-juvenile adult stage
3.20e4
  • 3.20e4
  • 3.98e4
  • 4.32e4
41.81
  • 41.81
  • 27.77
  • 21.54
AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0002358peritoneum
  • UBERON:0000104life cycle
3.23e4
  • 3.23e4
41.41
  • 41.41
AEIR
  • AEIR
UBERON:0000473testis
  • UBERON:0000111organogenesis stage
  • HsapDv:0000198fourth LMP month human stage (human)
  • UBERON:0000104life cycle
3.24e4
  • 3.24e4
  • 3.25e4
  • 3.33e4
41.10
  • 41.10
  • 41.07
  • 39.54
AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0001416skin of abdomen
  • HsapDv:000009025-44 year-old human stage (human)
  • HsapDv:0000088human early adulthood stage (human)
  • HsapDv:0000092human middle aged stage (human)
  • HsapDv:0000087human adult stage (human)
  • HsapDv:0000091human late adulthood stage (human)
3.41e4
  • 3.41e4
  • 4.05e4
  • 4.08e4
  • 4.08e4
  • 4.13e4
38.10
  • 38.10
  • 26.43
  • 25.95
  • 25.90
  • 25.07
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0001830minor salivary gland
  • HsapDv:0000092human middle aged stage (human)
  • HsapDv:0000087human adult stage (human)
  • HsapDv:0000091human late adulthood stage (human)
3.56e4
  • 3.56e4
  • 3.71e4
  • 3.90e4
35.29
  • 35.29
  • 32.73
  • 29.24
AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0035841esophagogastric junction muscularis propria
  • HsapDv:0000087human adult stage (human)
  • HsapDv:0000092human middle aged stage (human)
  • HsapDv:0000091human late adulthood stage (human)
3.65e4
  • 3.65e4
  • 3.84e4
  • 3.96e4
33.78
  • 33.78
  • 30.24
  • 28.17
AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0006631right atrium auricular region
  • HsapDv:0000092human middle aged stage (human)
  • HsapDv:0000091human late adulthood stage (human)
  • HsapDv:0000087human adult stage (human)
3.66e4
  • 3.66e4
  • 3.79e4
  • 3.83e4
33.62
  • 33.62
  • 31.15
  • 30.50
AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0010414omental fat pad
  • HsapDv:0000087human adult stage (human)
  • HsapDv:0000092human middle aged stage (human)
  • HsapDv:000009025-44 year-old human stage (human)
  • HsapDv:0000091human late adulthood stage (human)
  • HsapDv:0000088human early adulthood stage (human)
3.68e4
  • 3.68e4
  • 3.78e4
  • 3.81e4
  • 3.93e4
  • 3.97e4
33.13
  • 33.13
  • 31.45
  • 30.90
  • 28.60
  • 27.92
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0000996vagina
  • HsapDv:0000087human adult stage (human)
3.72e4
  • 3.72e4
32.44
  • 32.44
AEIR
  • AEIR
UBERON:0007610tibial artery
  • HsapDv:0000087human adult stage (human)
  • HsapDv:0000088human early adulthood stage (human)
  • HsapDv:0000091human late adulthood stage (human)
  • HsapDv:0000092human middle aged stage (human)
3.74e4
  • 3.74e4
  • 3.75e4
  • 4.03e4
  • 4.03e4
32.11
  • 32.11
  • 31.88
  • 26.89
  • 26.80
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0035805muscle layer of sigmoid colon
  • HsapDv:0000087human adult stage (human)
4.02e4
  • 4.02e4
26.99
  • 26.99
AEIR
  • AEIR
UBERON:0001511skin of leg
  • HsapDv:0000091human late adulthood stage (human)
  • HsapDv:0000087human adult stage (human)
4.04e4
  • 4.04e4
  • 4.19e4
26.71
  • 26.71
  • 23.93
AEIR
  • AEIR
  • AEIR
Sources
AAffymetrix
EEST
IIn Situ
RRNA-Seq
data
no data
Rank scores
3.25e4lightgrey: low confidence scores

important score variation

Rank scores of expression calls are normalized across genes, conditions and species. Low score means that the gene is highly expressed in the condition. Max rank score in all species: 4.10e4. Min rank score varies across species.

Expression scores of expression calls use the minimum and maximum Rank of the species to normalize the expression to a value between 0 and 100. Low score means that the gene is lowly expressed in the condition.

Sources of annotations to anatomy and development:
Sources of raw data:

Orthologs

Taxon nameSpecies with orthologsGene(s)Expression comparisonSee details
Homininae2 species2 genesCompare expression
Catarrhini3 species3 genesCompare expression
Euarchontoglires7 species7 genesCompare expression
Boreoeutheria13 species13 genesCompare expression
Theria14 species14 genesCompare expression
Mammalia15 species15 genesCompare expression
Amniota17 species17 genesCompare expression
Tetrapoda18 species18 genesCompare expression
Euteleostomi19 species19 genesCompare expression

Orthology information comes from OMA : ENSG00000157131.

Cross-references

CCDSCCDS606 (CCDS606.1)
EnsemblENSG00000157131 (C8A)
HGNCHGNC:1352 (C8A)
EMBLAL121998, BC132911, BC132913, M16974, U07996, U07997, U07998, U07999, U08000, U08001, U08002, U08003, U08004, U08005, U08006
OncoMXC8A (C8A)
Uniprot/SWISSPROTCO8A_HUMAN, P07357

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