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H. sapiens Gene: TLX3 - ENSG00000164438 - Homo sapiens (human)

General information

Ensembl IDENSG00000164438
NameTLX3
DescriptionT-cell leukemia homeobox 3 [Source:HGNC Symbol;Acc:HGNC:13532]
OrganismHomo sapiens (human)
Synonym(s)hox11l2, q96ad3, rnx
Orthologs(s)14 orthologs

Expression

Anat. entity IDAnatomical entityDevelopmental stage(s)Rank scoreExpression scoreSources
UBERON:0002245cerebellar hemisphere
  • HsapDv:000009465-79 year-old human stage (human)
  • HsapDv:0000092human middle aged stage (human)
  • HsapDv:000009025-44 year-old human stage (human)
  • HsapDv:0000091human late adulthood stage (human)
  • HsapDv:0000088human early adulthood stage (human)
  • HsapDv:0000087human adult stage (human)
  • UBERON:0000104life cycle
5.31e3
  • 5.31e3
  • 7.10e3
  • 7.66e3
  • 8.18e3
  • 8.54e3
  • 9.15e3
  • 3.22e4
90.36
  • 90.36
  • 87.10
  • 86.09
  • 85.14
  • 84.49
  • 83.39
  • 41.52
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0002037cerebellum
  • HsapDv:000009580 year-old and over human stage (human)
  • HsapDv:000009465-79 year-old human stage (human)
  • UBERON:0000104life cycle
  • HsapDv:0000087human adult stage (human)
  • HsapDv:000009025-44 year-old human stage (human)
  • HsapDv:0000092human middle aged stage (human)
5.39e3
  • 5.39e3
  • 7.53e3
  • 1.26e4
  • 2.34e4
  • 3.20e4
  • 3.23e4
90.22
  • 90.22
  • 86.33
  • 77.07
  • 57.44
  • 41.86
  • 41.39
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0014890right hemisphere of cerebellum
  • HsapDv:000009465-79 year-old human stage (human)
  • HsapDv:0000088human early adulthood stage (human)
  • HsapDv:000009025-44 year-old human stage (human)
  • HsapDv:0000092human middle aged stage (human)
  • HsapDv:0000087human adult stage (human)
  • HsapDv:0000091human late adulthood stage (human)
5.74e3
  • 5.74e3
  • 6.35e3
  • 6.43e3
  • 7.25e3
  • 7.71e3
  • 8.52e3
89.58
  • 89.58
  • 88.47
  • 88.33
  • 86.83
  • 86.00
  • 84.53
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0006469C1 segment of cervical spinal cord
  • HsapDv:000009025-44 year-old human stage (human)
  • HsapDv:0000088human early adulthood stage (human)
  • HsapDv:0000087human adult stage (human)
  • HsapDv:0000091human late adulthood stage (human)
  • HsapDv:0000092human middle aged stage (human)
1.51e4
  • 1.51e4
  • 1.67e4
  • 1.89e4
  • 2.82e4
  • 2.85e4
72.62
  • 72.62
  • 69.75
  • 65.73
  • 48.75
  • 48.31
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0000007pituitary gland
  • HsapDv:0000091human late adulthood stage (human)
  • HsapDv:0000092human middle aged stage (human)
  • HsapDv:0000087human adult stage (human)
2.80e4
  • 2.80e4
  • 3.05e4
  • 3.09e4
49.10
  • 49.10
  • 44.70
  • 43.83
AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0002196adenohypophysis
  • HsapDv:0000091human late adulthood stage (human)
  • HsapDv:0000087human adult stage (human)
2.85e4
  • 2.85e4
  • 3.06e4
48.27
  • 48.27
  • 44.38
AEIR
  • AEIR
  • AEIR
UBERON:0000956cerebral cortex
  • HsapDv:0000092human middle aged stage (human)
  • UBERON:0000113post-juvenile adult stage
2.91e4
  • 2.91e4
  • 4.49e4
47.16
  • 47.16
  • 18.51
AEIR
  • AEIR
  • AEIR
UBERON:0000014zone of skin
  • UBERON:0000104life cycle
  • HsapDv:0000087human adult stage (human)
  • UBERON:0000113post-juvenile adult stage
3.19e4
  • 3.19e4
  • 3.22e4
  • 4.38e4
42.13
  • 42.13
  • 41.52
  • 20.52
AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0000178blood
  • HsapDv:000009025-44 year-old human stage (human)
  • UBERON:0000104life cycle
  • UBERON:0000113post-juvenile adult stage
  • HsapDv:0000088human early adulthood stage (human)
  • HsapDv:0000087human adult stage (human)
3.20e4
  • 3.20e4
  • 3.56e4
  • 3.74e4
  • 4.06e4
  • 4.14e4
41.86
  • 41.86
  • 35.32
  • 32.01
  • 26.26
  • 24.87
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0001870frontal cortex
  • UBERON:0000104life cycle
  • HsapDv:0000092human middle aged stage (human)
  • HsapDv:0000087human adult stage (human)
3.22e4
  • 3.22e4
  • 3.68e4
  • 4.66e4
41.61
  • 41.61
  • 33.27
  • 15.32
AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0000474female reproductive system
  • UBERON:0000104life cycle
3.22e4
  • 3.22e4
41.51
  • 41.51
AEIR
  • AEIR
UBERON:0000996vagina
  • HsapDv:0000092human middle aged stage (human)
  • HsapDv:0000088human early adulthood stage (human)
  • HsapDv:0000087human adult stage (human)
  • HsapDv:0000091human late adulthood stage (human)
3.76e4
  • 3.76e4
  • 3.90e4
  • 4.26e4
  • 4.26e4
31.74
  • 31.74
  • 29.14
  • 22.70
  • 22.59
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0009834dorsolateral prefrontal cortex
  • HsapDv:000009465-79 year-old human stage (human)
  • HsapDv:0000091human late adulthood stage (human)
  • HsapDv:0000087human adult stage (human)
3.78e4
  • 3.78e4
  • 4.39e4
  • 4.49e4
31.38
  • 31.38
  • 20.36
  • 18.53
AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0002810right frontal lobe
  • HsapDv:0000092human middle aged stage (human)
  • HsapDv:0000091human late adulthood stage (human)
  • HsapDv:0000087human adult stage (human)
3.89e4
  • 3.89e4
  • 3.92e4
  • 4.38e4
29.38
  • 29.38
  • 28.80
  • 20.51
AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0001043esophagus
  • UBERON:0000113post-juvenile adult stage
  • HsapDv:0000087human adult stage (human)
3.94e4
  • 3.94e4
  • 4.55e4
28.38
  • 28.38
  • 17.43
AEIR
  • AEIR
  • AEIR
UBERON:0002469esophagus mucosa
  • HsapDv:0000091human late adulthood stage (human)
  • HsapDv:0000087human adult stage (human)
4.06e4
  • 4.06e4
  • 4.27e4
26.28
  • 26.28
  • 22.43
AEIR
  • AEIR
  • AEIR
UBERON:0001511skin of leg
  • HsapDv:0000091human late adulthood stage (human)
  • HsapDv:0000087human adult stage (human)
4.07e4
  • 4.07e4
  • 4.21e4
26.13
  • 26.13
  • 23.56
AEIR
  • AEIR
  • AEIR
UBERON:0013540Brodmann (1909) area 9
  • HsapDv:000009465-79 year-old human stage (human)
4.14e4
  • 4.14e4
24.87
  • 24.87
AEIR
  • AEIR
UBERON:0001388gastrocnemius
  • HsapDv:0000091human late adulthood stage (human)
  • HsapDv:0000092human middle aged stage (human)
  • HsapDv:0000087human adult stage (human)
4.22e4
  • 4.22e4
  • 4.23e4
  • 4.35e4
23.34
  • 23.34
  • 23.22
  • 20.98
AEIR
  • AEIR
  • AEIR
  • AEIR
Sources
AAffymetrix
EEST
IIn Situ
RRNA-Seq
data
no data
Rank scores
3.25e4lightgrey: low confidence scores

important score variation

Rank scores of expression calls are normalized across genes, conditions and species. Low score means that the gene is highly expressed in the condition. Max rank score in all species: 4.10e4. Min rank score varies across species.

Expression scores of expression calls use the minimum and maximum Rank of the species to normalize the expression to a value between 0 and 100. Low score means that the gene is lowly expressed in the condition.

Sources of annotations to anatomy and development:
  • Affymetrix data: Bgee
  • RNA-Seq data: Bgee
Sources of raw data:

Orthologs

Taxon nameSpecies with orthologsGene(s)Expression comparisonSee details
Homininae2 species2 genesCompare expression
Euarchontoglires6 species6 genesCompare expression
Boreoeutheria11 species12 genesCompare expression
Amniota12 species13 genesCompare expression
Tetrapoda13 species14 genesCompare expression

Orthology information comes from OMA : ENSG00000164438.

Cross-references

CCDSCCDS34288 (CCDS34288.1)
EnsemblENSG00000164438 (TLX3)
HGNCHGNC:13532 (TLX3)
EMBLAJ223798, AJ223799, AJ223800, BC017291
OncoMXTLX3 (TLX3)
Uniprot/SWISSPROTO43711, TLX3_HUMAN

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