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H. sapiens Gene: MYH4 - ENSG00000264424 - Homo sapiens (human)

General information

Ensembl IDENSG00000264424
NameMYH4
Descriptionmyosin, heavy chain 4, skeletal muscle [Source:HGNC Symbol;Acc:HGNC:7574]
OrganismHomo sapiens (human)
Synonym(s)myh2b, myhc-2b, myhc-iib
Orthologs(s)39 orthologs
Paralog(s)12 paralogs

Expression

Anat. entity IDAnatomical entityDevelopmental stage(s)Rank scoreExpression scoreSources
UBERON:0001379vastus lateralis
  • UBERON:0000113post-juvenile adult stage
  • HsapDv:0000093human aged stage
  • HsapDv:000009025-44 year-old human stage (human)
  • HsapDv:0000089young adult stage (human)
  • HsapDv:000009465-79 year-old human stage (human)
  • HsapDv:0000087human adult stage (human)
  • UBERON:0000104life cycle
  • HsapDv:0000092human middle aged stage (human)
  • HsapDv:0000091human late adulthood stage (human)
2.71e3
  • 2.71e3
  • 2.90e3
  • 3.37e3
  • 4.59e3
  • 5.00e3
  • 5.75e3
  • 6.00e3
  • 6.47e3
  • 6.91e3
95.08
  • 95.08
  • 94.73
  • 93.88
  • 91.67
  • 90.93
  • 89.55
  • 89.11
  • 88.25
  • 87.45
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0004511skeletal muscle tissue of rectus abdominis
  • HsapDv:000009465-79 year-old human stage (human)
  • HsapDv:0000092human middle aged stage (human)
3.11e3
  • 3.11e3
  • 3.34e3
94.36
  • 94.36
  • 93.94
AEIR
  • AEIR
  • AEIR
UBERON:0001377quadriceps femoris
  • HsapDv:00000842-5 year-old child stage (human)
  • HsapDv:0000092human middle aged stage (human)
  • UBERON:0034920infant stage
  • HsapDv:000009025-44 year-old human stage (human)
  • HsapDv:000009465-79 year-old human stage (human)
  • HsapDv:0000086adolescent stage (human)
  • HsapDv:0000089young adult stage (human)
  • HsapDv:000009580 year-old and over human stage (human)
  • UBERON:0000104life cycle
  • HsapDv:0000093human aged stage
4.56e3
  • 4.56e3
  • 5.03e3
  • 6.00e3
  • 6.69e3
  • 6.78e3
  • 8.05e3
  • 9.52e3
  • 1.07e4
  • 1.39e4
  • 1.42e4
91.72
  • 91.72
  • 90.86
  • 89.11
  • 87.85
  • 87.69
  • 85.38
  • 82.71
  • 80.65
  • 74.79
  • 74.21
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0001134skeletal muscle tissue
  • HsapDv:0000089young adult stage (human)
  • HsapDv:0000087human adult stage (human)
  • HsapDv:000009025-44 year-old human stage (human)
  • UBERON:0000104life cycle
  • UBERON:0000113post-juvenile adult stage
  • UBERON:0034919juvenile stage
  • HsapDv:000009465-79 year-old human stage (human)
  • HsapDv:0000092human middle aged stage (human)
5.57e3
  • 5.57e3
  • 6.51e3
  • 6.73e3
  • 7.96e3
  • 8.59e3
  • 1.59e4
  • 1.59e4
  • 1.73e4
89.88
  • 89.88
  • 88.19
  • 87.78
  • 85.54
  • 84.41
  • 71.18
  • 71.11
  • 68.55
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0001476deltoid
  • HsapDv:0000092human middle aged stage (human)
  • UBERON:0000104life cycle
  • HsapDv:000009025-44 year-old human stage (human)
  • HsapDv:0000089young adult stage (human)
  • HsapDv:000009465-79 year-old human stage (human)
  • HsapDv:0000093human aged stage
7.29e3
  • 7.29e3
  • 9.18e3
  • 9.23e3
  • 9.35e3
  • 9.93e3
  • 1.69e4
86.76
  • 86.76
  • 83.33
  • 83.24
  • 83.02
  • 81.97
  • 69.29
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0001507biceps brachii
  • UBERON:0000113post-juvenile adult stage
  • HsapDv:000009025-44 year-old human stage (human)
  • HsapDv:0000086adolescent stage (human)
8.07e3
  • 8.07e3
  • 8.26e3
  • 1.06e4
85.34
  • 85.34
  • 85.01
  • 80.81
AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0004502skeletal muscle tissue of biceps brachii
  • HsapDv:0000093human aged stage
9.10e3
  • 9.10e3
83.48
  • 83.48
AEIR
  • AEIR
UBERON:0001388gastrocnemius
  • UBERON:0000104life cycle
  • HsapDv:000009465-79 year-old human stage (human)
  • HsapDv:0000093human aged stage
  • HsapDv:0000091human late adulthood stage (human)
  • HsapDv:0000092human middle aged stage (human)
  • HsapDv:0000088human early adulthood stage (human)
  • HsapDv:0000087human adult stage (human)
  • HsapDv:000009025-44 year-old human stage (human)
1.23e4
  • 1.23e4
  • 1.41e4
  • 1.45e4
  • 1.78e4
  • 1.81e4
  • 1.84e4
  • 1.94e4
  • 1.98e4
77.70
  • 77.70
  • 74.49
  • 73.69
  • 67.62
  • 67.20
  • 66.60
  • 64.80
  • 64.07
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0001383muscle of leg
  • HsapDv:0000088human early adulthood stage (human)
1.25e4
  • 1.25e4
77.38
  • 77.38
AEIR
  • AEIR
UBERON:0004252hindlimb stylopod muscle
  • UBERON:0000104life cycle
1.25e4
  • 1.25e4
77.37
  • 77.37
AEIR
  • AEIR
UBERON:0002349myocardium
  • HsapDv:0000087human adult stage (human)
  • HsapDv:0000086adolescent stage (human)
  • HsapDv:00000842-5 year-old child stage (human)
  • HsapDv:0000092human middle aged stage (human)
  • HsapDv:000009025-44 year-old human stage (human)
1.53e4
  • 1.53e4
  • 1.81e4
  • 1.82e4
  • 1.83e4
  • 1.83e4
72.15
  • 72.15
  • 67.15
  • 66.88
  • 66.83
  • 66.78
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0002115jejunum
  • UBERON:0000104life cycle
1.54e4
  • 1.54e4
72.00
  • 72.00
AEIR
  • AEIR
UBERON:0001103diaphragm
  • UBERON:0000104life cycle
1.56e4
  • 1.56e4
71.62
  • 71.62
AEIR
  • AEIR
UBERON:0011876body of tongue
  • HsapDv:000009025-44 year-old human stage (human)
2.08e4
  • 2.08e4
62.27
  • 62.27
AEIR
  • AEIR
UBERON:0003379cardiac muscle of right atrium
  • HsapDv:0000092human middle aged stage (human)
  • HsapDv:000009025-44 year-old human stage (human)
  • HsapDv:000009465-79 year-old human stage (human)
2.10e4
  • 2.10e4
  • 2.10e4
  • 2.17e4
61.96
  • 61.96
  • 61.79
  • 60.58
AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0002084heart left ventricle
  • UBERON:0000104life cycle
  • HsapDv:000009465-79 year-old human stage (human)
  • HsapDv:0000088human early adulthood stage (human)
  • HsapDv:0000087human adult stage (human)
  • HsapDv:0000092human middle aged stage (human)
  • HsapDv:000009025-44 year-old human stage (human)
  • HsapDv:0000091human late adulthood stage (human)
2.18e4
  • 2.18e4
  • 2.48e4
  • 2.81e4
  • 2.93e4
  • 2.99e4
  • 3.02e4
  • 3.10e4
60.35
  • 60.35
  • 55.05
  • 48.99
  • 46.82
  • 45.64
  • 45.22
  • 43.73
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0002080heart right ventricle
  • HsapDv:0000092human middle aged stage (human)
  • HsapDv:0000089young adult stage (human)
  • UBERON:0000104life cycle
2.21e4
  • 2.21e4
  • 2.23e4
  • 2.24e4
59.84
  • 59.84
  • 59.47
  • 59.30
AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0001871temporal lobe
  • HsapDv:0000089young adult stage (human)
  • HsapDv:000009465-79 year-old human stage (human)
2.49e4
  • 2.49e4
  • 3.40e4
54.87
  • 54.87
  • 38.34
AEIR
  • AEIR
  • AEIR
UBERON:0000043tendon
  • HsapDv:0000092human middle aged stage (human)
2.49e4
  • 2.49e4
54.73
  • 54.73
AEIR
  • AEIR
UBERON:0002217synovial joint
  • UBERON:0000104life cycle
2.50e4
  • 2.50e4
54.65
  • 54.65
AEIR
  • AEIR
UBERON:0002082cardiac ventricle
  • HsapDv:000009025-44 year-old human stage (human)
2.52e4
  • 2.52e4
54.21
  • 54.21
AEIR
  • AEIR
UBERON:0005343cortical plate
  • HsapDv:0000198fourth LMP month human stage (human)
2.61e4
  • 2.61e4
52.56
  • 52.56
AEIR
  • AEIR
UBERON:0000955brain
  • UBERON:0007220late embryonic stage
  • HsapDv:0000092human middle aged stage (human)
  • HsapDv:000009025-44 year-old human stage (human)
  • HsapDv:0000089young adult stage (human)
  • HsapDv:000009580 year-old and over human stage (human)
  • UBERON:0000104life cycle
  • HsapDv:000009465-79 year-old human stage (human)
  • HsapDv:0000087human adult stage (human)
2.70e4
  • 2.70e4
  • 2.96e4
  • 3.01e4
  • 3.07e4
  • 3.11e4
  • 3.23e4
  • 3.24e4
  • 4.04e4
51.04
  • 51.04
  • 46.33
  • 45.34
  • 44.29
  • 43.47
  • 41.29
  • 41.12
  • 26.67
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0001898hypothalamus
  • UBERON:0000113post-juvenile adult stage
  • UBERON:0000104life cycle
  • HsapDv:0000087human adult stage (human)
  • HsapDv:0000092human middle aged stage (human)
  • HsapDv:0000091human late adulthood stage (human)
2.76e4
  • 2.76e4
  • 3.29e4
  • 3.69e4
  • 3.74e4
  • 3.82e4
49.85
  • 49.85
  • 40.33
  • 32.96
  • 32.06
  • 30.70
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0007616layer of synovial tissue
  • UBERON:0000104life cycle
2.80e4
  • 2.80e4
49.09
  • 49.09
AEIR
  • AEIR
UBERON:0002483trabecular bone tissue
  • HsapDv:000009465-79 year-old human stage (human)
  • HsapDv:000009025-44 year-old human stage (human)
2.87e4
  • 2.87e4
  • 2.97e4
47.91
  • 47.91
  • 46.01
AEIR
  • AEIR
  • AEIR
UBERON:0001870frontal cortex
  • HsapDv:0000092human middle aged stage (human)
  • HsapDv:0000087human adult stage (human)
  • UBERON:0000104life cycle
  • HsapDv:000009025-44 year-old human stage (human)
3.06e4
  • 3.06e4
  • 3.13e4
  • 3.22e4
  • 3.22e4
44.49
  • 44.49
  • 43.18
  • 41.61
  • 41.53
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0000355pharyngeal mucosa
  • HsapDv:000009025-44 year-old human stage (human)
3.06e4
  • 3.06e4
44.46
  • 44.46
AEIR
  • AEIR
UBERON:0000167oral cavity
  • HsapDv:0000088human early adulthood stage (human)
  • HsapDv:0000087human adult stage (human)
3.06e4
  • 3.06e4
  • 3.14e4
44.40
  • 44.40
  • 43.06
AEIR
  • AEIR
  • AEIR
UBERON:0000014zone of skin
  • UBERON:0000104life cycle
  • UBERON:0000113post-juvenile adult stage
3.15e4
  • 3.15e4
  • 3.95e4
42.75
  • 42.75
  • 28.27
AEIR
  • AEIR
  • AEIR
UBERON:0000956cerebral cortex
  • HsapDv:0000198fourth LMP month human stage (human)
  • HsapDv:000009025-44 year-old human stage (human)
  • HsapDv:0000092human middle aged stage (human)
  • UBERON:0000113post-juvenile adult stage
3.17e4
  • 3.17e4
  • 3.21e4
  • 3.23e4
  • 3.93e4
42.38
  • 42.38
  • 41.63
  • 41.44
  • 28.60
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0002107liver
  • UBERON:0034920infant stage
  • UBERON:0000104life cycle
  • HsapDv:0000087human adult stage (human)
  • UBERON:0000113post-juvenile adult stage
3.20e4
  • 3.20e4
  • 3.37e4
  • 3.65e4
  • 4.35e4
41.96
  • 41.96
  • 38.82
  • 33.74
  • 21.07
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0000451prefrontal cortex
  • UBERON:0000104life cycle
  • HsapDv:000009025-44 year-old human stage (human)
3.22e4
  • 3.22e4
  • 3.55e4
41.59
  • 41.59
  • 35.59
AEIR
  • AEIR
  • AEIR
UBERON:0001114right lobe of liver
  • HsapDv:0000091human late adulthood stage (human)
  • HsapDv:0000087human adult stage (human)
3.35e4
  • 3.35e4
  • 3.60e4
39.11
  • 39.11
  • 34.54
AEIR
  • AEIR
  • AEIR
UBERON:0035841esophagogastric junction muscularis propria
  • HsapDv:0000088human early adulthood stage (human)
  • HsapDv:0000087human adult stage (human)
3.89e4
  • 3.89e4
  • 4.02e4
29.39
  • 29.39
  • 27.04
AEIR
  • AEIR
  • AEIR
Sources
AAffymetrix
EEST
IIn Situ
RRNA-Seq
data
no data
Rank scores
3.25e4lightgrey: low confidence scores

important score variation

Rank scores of expression calls are normalized across genes, conditions and species. Low score means that the gene is highly expressed in the condition. Max rank score in all species: 4.10e4. Min rank score varies across species.

Expression scores of expression calls use the minimum and maximum Rank of the species to normalize the expression to a value between 0 and 100. Low score means that the gene is lowly expressed in the condition.

Sources of annotations to anatomy and development:
  • Affymetrix data: Bgee
  • RNA-Seq data: Bgee
Sources of raw data:

Orthologs

Taxon nameSpecies with orthologsGene(s)Expression comparisonSee details
Homininae1 species1 geneCompare expression
Catarrhini2 species2 genesCompare expression
Euarchontoglires5 species5 genesCompare expression
Boreoeutheria10 species10 genesCompare expression
Theria11 species11 genesCompare expression
Amniota13 species20 genesCompare expression
Tetrapoda14 species21 genesCompare expression
Euteleostomi15 species29 genesCompare expression
Bilateria21 species39 genesCompare expression

Orthology information comes from OMA : ENSG00000264424.

Paralogs (same species)

Cross-references

CCDSCCDS11154 (CCDS11154.1)
EnsemblENSG00000264424 (MYH4)
HGNCHGNC:7574 (MYH4)
EMBLAC005323, AF111783
OncoMXMYH4 (MYH4)
Uniprot/SWISSPROTMYH4_HUMAN, Q9Y623

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