Gene: Gjb2 - ENSRNOG00000008855 - Rattus norvegicus (rat)

General information

Ensembl ID	ENSRNOG00000008855
Name	Gjb2
Description	gap junction protein, beta 2 [Source:RGD Symbol;Acc:728891]
Organism	Rattus norvegicus (rat)
Synonym(s)	cx26, cxn-26, mgc93804
Orthologs(s)	15 orthologs
Paralog(s)	3 paralogs

Expression

Anat. entity ID	Anatomical entity	Developmental stage(s)	Rank score	Expression score	Sources
UBERON:0001043	esophagus	[+] 1 stage UBERON:0000113post-juvenile adult stage	1.11e3 1.11e3	95.96 95.96	AEIR AEIR
UBERON:0002113	kidney	[+] 1 stage UBERON:0000113post-juvenile adult stage	1.47e3 1.47e3	94.65 94.65	AEIR AEIR
UBERON:0000082	adult mammalian kidney	[+] 1 stage UBERON:0000113post-juvenile adult stage	1.89e3 1.89e3	93.11 93.11	AEIR AEIR
UBERON:0002107	liver	[+] 3 stages RnorDv:00000194-6-month-old stage (rat) UBERON:0000113post-juvenile adult stage UBERON:0034920infant stage	2.29e3 2.29e3 4.26e3 4.80e3	91.66 91.66 84.49 82.51	AEIR AEIR AEIR AEIR
UBERON:0001264	pancreas	[+] 1 stage UBERON:0000113post-juvenile adult stage	2.50e3 2.50e3	90.89 90.89	AEIR AEIR
UBERON:0002370	thymus	[+] 1 stage UBERON:0000113post-juvenile adult stage	4.89e3 4.89e3	82.17 82.17	AEIR AEIR
UBERON:0002114	duodenum	[+] 1 stage UBERON:0000113post-juvenile adult stage	4.92e3 4.92e3	82.09 82.09	AEIR AEIR
UBERON:0000945	stomach	[+] 1 stage UBERON:0000113post-juvenile adult stage	6.30e3 6.30e3	77.06 77.06	AEIR AEIR
UBERON:0002115	jejunum	[+] 1 stage UBERON:0000113post-juvenile adult stage	6.36e3 6.36e3	76.85 76.85	AEIR AEIR
UBERON:0001870	frontal cortex	[+] 2 stages UBERON:0000113post-juvenile adult stage UBERON:0000104life cycle	7.18e3 7.18e3 9.30e3	73.84 73.84 66.12	AEIR AEIR AEIR
UBERON:0002116	ileum	[+] 1 stage UBERON:0000113post-juvenile adult stage	8.40e3 8.40e3	69.41 69.41	AEIR AEIR
UBERON:0002037	cerebellum	[+] 1 stage UBERON:0000113post-juvenile adult stage	8.88e3 8.88e3	67.64 67.64	AEIR AEIR
UBERON:0001155	colon	[+] 1 stage UBERON:0000113post-juvenile adult stage	1.03e4 1.03e4	62.60 62.60	AEIR AEIR
UBERON:0000992	female gonad	[+] 1 stage UBERON:0000113post-juvenile adult stage	1.39e4 1.39e4	49.49 49.49	AEIR AEIR
UBERON:0001377	quadriceps femoris	[+] 1 stage UBERON:0000113post-juvenile adult stage	1.43e4 1.43e4	47.84 47.84	AEIR AEIR
UBERON:0001134	skeletal muscle tissue	[+] 1 stage UBERON:0000113post-juvenile adult stage	1.43e4 1.43e4	47.81 47.81	AEIR AEIR
UBERON:0002106	spleen	[+] 1 stage UBERON:0000113post-juvenile adult stage	1.44e4 1.44e4	47.55 47.55	AEIR AEIR
UBERON:0002048	lung	[+] 1 stage UBERON:0000113post-juvenile adult stage	1.46e4 1.46e4	46.75 46.75	AEIR AEIR
UBERON:0001954	Ammon's horn	[+] 2 stages UBERON:0000113post-juvenile adult stage RnorDv:00000194-6-month-old stage (rat)	1.47e4 1.47e4 1.49e4	46.38 46.38 45.61	AEIR AEIR AEIR
UBERON:0000948	heart	[+] 1 stage UBERON:0000113post-juvenile adult stage	1.75e4 1.75e4	36.18 36.18	AEIR AEIR
UBERON:0000473	testis	[+] 2 stages UBERON:0000113post-juvenile adult stage UBERON:0000104life cycle	1.96e4 1.96e4 2.26e4	28.77 28.77 17.63	AEIR AEIR AEIR

Sources
A	Affymetrix
E	EST
I	In Situ
R	RNA-Seq

data

no data

Rank scores
3.25e4	lightgrey: low confidence scores
	important score variation

Rank scores of expression calls are normalized across genes, conditions and species. Low score means that the gene is highly expressed in the condition. Max rank score in all species: 4.10e4. Min rank score varies across species.

Expression scores of expression calls use the minimum and maximum Rank of the species to normalize the expression to a value between 0 and 100. Low score means that the gene is lowly expressed in the condition.

Sources of annotations to anatomy and development:

Affymetrix data: Bgee
RNA-Seq data: Bgee

Sources of raw data:

Affymetrix data: GEO
RNA-Seq data: GEO

Orthologs

Taxon name	Species with orthologs	Gene(s)	Expression comparison	See details
Murinae	1 species Mus musculus (mouse)	1 gene ENSMUSG00000046352 Gjb2	Compare expression	[+]
Rodentia	2 species Mus musculus (mouse) Cavia porcellus (guinea pig)	2 genes ENSMUSG00000046352 Gjb2 ENSCPOG00000006174 GJB2	Compare expression	[+]
Glires	3 species Mus musculus (mouse) Oryctolagus cuniculus (rabbit) Cavia porcellus (guinea pig)	3 genes ENSMUSG00000046352 Gjb2 ENSOCUG00000010156 GJB2 ENSCPOG00000006174 GJB2	Compare expression	[+]
Euarchontoglires	6 species Homo sapiens (human) Mus musculus (mouse) Gorilla gorilla (gorilla) Macaca mulatta (macaque) Oryctolagus cuniculus (rabbit) Cavia porcellus (guinea pig)	6 genes ENSG00000165474 GJB2 ENSMUSG00000046352 Gjb2 ENSGGOG00000016693 GJB2 ENSMMUG00000010522 GJB2 ENSOCUG00000010156 GJB2 ENSCPOG00000006174 GJB2	Compare expression	[+]
Boreoeutheria	10 species Homo sapiens (human) Mus musculus (mouse) Gorilla gorilla (gorilla) Macaca mulatta (macaque) Bos taurus (cattle) Equus caballus (horse) Oryctolagus cuniculus (rabbit) Canis lupus familiaris (dog) Felis catus (cat) Cavia porcellus (guinea pig)	10 genes ENSG00000165474 GJB2 ENSMUSG00000046352 Gjb2 ENSGGOG00000016693 GJB2 ENSMMUG00000010522 GJB2 ENSBTAG00000017425 GJB2 ENSECAG00000001724 GJB2 ENSOCUG00000010156 GJB2 ENSCAFG00000029537 GJB2 ENSFCAG00000006961 GJB2 ENSCPOG00000006174 GJB2	Compare expression	[+]
Theria	11 species Homo sapiens (human) Mus musculus (mouse) Gorilla gorilla (gorilla) Macaca mulatta (macaque) Bos taurus (cattle) Equus caballus (horse) Oryctolagus cuniculus (rabbit) Canis lupus familiaris (dog) Felis catus (cat) Cavia porcellus (guinea pig) Monodelphis domestica (opossum)	11 genes ENSG00000165474 GJB2 ENSMUSG00000046352 Gjb2 ENSGGOG00000016693 GJB2 ENSMMUG00000010522 GJB2 ENSBTAG00000017425 GJB2 ENSECAG00000001724 GJB2 ENSOCUG00000010156 GJB2 ENSCAFG00000029537 GJB2 ENSFCAG00000006961 GJB2 ENSCPOG00000006174 GJB2 ENSMODG00000024159 GJB2	Compare expression	[+]
Mammalia	12 species Homo sapiens (human) Mus musculus (mouse) Gorilla gorilla (gorilla) Macaca mulatta (macaque) Bos taurus (cattle) Equus caballus (horse) Oryctolagus cuniculus (rabbit) Canis lupus familiaris (dog) Felis catus (cat) Cavia porcellus (guinea pig) Monodelphis domestica (opossum) Ornithorhynchus anatinus (platypus)	12 genes ENSG00000165474 GJB2 ENSMUSG00000046352 Gjb2 ENSGGOG00000016693 GJB2 ENSMMUG00000010522 GJB2 ENSBTAG00000017425 GJB2 ENSECAG00000001724 GJB2 ENSOCUG00000010156 GJB2 ENSCAFG00000029537 GJB2 ENSFCAG00000006961 GJB2 ENSCPOG00000006174 GJB2 ENSMODG00000024159 GJB2 ENSOANG00000009021 GJB2	Compare expression	[+]
Amniota	13 species Homo sapiens (human) Mus musculus (mouse) Gorilla gorilla (gorilla) Macaca mulatta (macaque) Bos taurus (cattle) Equus caballus (horse) Oryctolagus cuniculus (rabbit) Canis lupus familiaris (dog) Felis catus (cat) Cavia porcellus (guinea pig) Monodelphis domestica (opossum) Ornithorhynchus anatinus (platypus) Gallus gallus (chicken)	13 genes ENSG00000165474 GJB2 ENSMUSG00000046352 Gjb2 ENSGGOG00000016693 GJB2 ENSMMUG00000010522 GJB2 ENSBTAG00000017425 GJB2 ENSECAG00000001724 GJB2 ENSOCUG00000010156 GJB2 ENSCAFG00000029537 GJB2 ENSFCAG00000006961 GJB2 ENSCPOG00000006174 GJB2 ENSMODG00000024159 GJB2 ENSOANG00000009021 GJB2 ENSGALG00000017136 GJB6	Compare expression	[+]
Tetrapoda	14 species Homo sapiens (human) Mus musculus (mouse) Gorilla gorilla (gorilla) Macaca mulatta (macaque) Bos taurus (cattle) Equus caballus (horse) Oryctolagus cuniculus (rabbit) Canis lupus familiaris (dog) Felis catus (cat) Cavia porcellus (guinea pig) Monodelphis domestica (opossum) Ornithorhynchus anatinus (platypus) Gallus gallus (chicken) Xenopus tropicalis (western clawed frog)	14 genes ENSG00000165474 GJB2 ENSMUSG00000046352 Gjb2 ENSGGOG00000016693 GJB2 ENSMMUG00000010522 GJB2 ENSBTAG00000017425 GJB2 ENSECAG00000001724 GJB2 ENSOCUG00000010156 GJB2 ENSCAFG00000029537 GJB2 ENSFCAG00000006961 GJB2 ENSCPOG00000006174 GJB2 ENSMODG00000024159 GJB2 ENSOANG00000009021 GJB2 ENSGALG00000017136 GJB6 ENSXETG00000026112 gjb2	Compare expression	[+]
Euteleostomi	15 species Homo sapiens (human) Mus musculus (mouse) Danio rerio (zebrafish) Gorilla gorilla (gorilla) Macaca mulatta (macaque) Bos taurus (cattle) Equus caballus (horse) Oryctolagus cuniculus (rabbit) Canis lupus familiaris (dog) Felis catus (cat) Cavia porcellus (guinea pig) Monodelphis domestica (opossum) Ornithorhynchus anatinus (platypus) Gallus gallus (chicken) Xenopus tropicalis (western clawed frog)	15 genes ENSG00000165474 GJB2 ENSMUSG00000046352 Gjb2 ENSDARG00000042707 cx30.3 ENSGGOG00000016693 GJB2 ENSMMUG00000010522 GJB2 ENSBTAG00000017425 GJB2 ENSECAG00000001724 GJB2 ENSOCUG00000010156 GJB2 ENSCAFG00000029537 GJB2 ENSFCAG00000006961 GJB2 ENSCPOG00000006174 GJB2 ENSMODG00000024159 GJB2 ENSOANG00000009021 GJB2 ENSGALG00000017136 GJB6 ENSXETG00000026112 gjb2	Compare expression	[+]

Orthology information comes from OMA : ENSRNOG00000008855.

Paralogs (same species)

Taxon name	Gene(s)	Expression comparison	See details
Sarcopterygii	1 gene ENSRNOG00000022116 Gjb6	Compare expression	[+]
Chordata	3 genes ENSRNOG00000003746 Gjb1 ENSRNOG00000014372 Gjb3 ENSRNOG00000022116 Gjb6	Compare expression	[+]

Paralogy information comes from OMA : ENSRNOG00000008855.

Cross-references

Ensembl	ENSRNOG00000008855 (Gjb2)
RGD	728891 (Gjb2)
EMBL	BC078952
Uniprot/SWISSPROT	CXB2_RAT, P21994