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D. melanogaster Gene: Keap1 - FBgn0038475 - Drosophila melanogaster (fruit fly)

General information

Ensembl IDFBgn0038475
NameKeap1
DescriptionKeap1 [Source:FlyBase gene name;Acc:FBgn0038475]
OrganismDrosophila melanogaster (fruit fly)
Synonym(s)cg3962, cg3962-pa, cg3962-pb, cg3962-pc, cg3962-ra, cg3962-rb, cg3962-rc, dkeap-1, dkeap1, dmel\cg3962, keap1, nrf-2
Orthologs(s)24 orthologs
Paralog(s)5 paralogs

Expression

Anat. entity IDAnatomical entityDevelopmental stage(s)Rank scoreExpression scoreSources
UBERON:0000922embryo
  • FBdv:00005312embryonic cycle 14 (Drosophila)
  • FBdv:00014201early extended germ band stage (Drosophila)
  • FBdv:00005311embryonic stage 5 (Drosophila)
  • FBdv:00004450late extended germ band stage (Drosophila)
  • FBdv:00005321extended germ band stage (Drosophila)
  • FBdv:00005324embryonic stage 10 (Drosophila)
  • FBdv:00005331dorsal closure stage (Drosophila)
  • FBdv:00005290pre-blastoderm stage (Drosophila)
  • FBdv:00005306embryonic stage 4 (Drosophila)
  • FBdv:00005309embryonic cycle 13 (Drosophila)
  • UBERON:0000068embryo stage
  • FBdv:00005335embryonic stage 17 (Drosophila)
  • FBdv:00005304blastoderm stage (Drosophila)
  • FBdv:00005334embryonic stage 16 (Drosophila)
  • FBdv:00005332embryonic stage 15 (Drosophila)
  • FBdv:00005293embryonic stage 2 (Drosophila)
2.54e3
  • 2.54e3
  • 3.66e3
  • 3.93e3
  • 3.99e3
  • 4.15e3
  • 4.56e3
  • 4.62e3
  • 5.15e3
  • 5.20e3
  • 5.21e3
  • 5.41e3
  • 5.85e3
  • 6.22e3
  • 6.89e3
  • 7.39e3
  • 7.83e3
85.26
  • 85.26
  • 78.81
  • 77.20
  • 76.88
  • 75.95
  • 73.55
  • 73.24
  • 70.12
  • 69.86
  • 69.82
  • 68.66
  • 66.11
  • 63.97
  • 60.08
  • 57.14
  • 54.60
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
FBbt:00004520mouthpart (Drosophila)
  • UBERON:0000066fully formed stage
3.18e3
  • 3.18e3
81.56
  • 81.56
AEIR
  • AEIR
UBERON:0000972antenna
  • UBERON:0000066fully formed stage
3.32e3
  • 3.32e3
80.75
  • 80.75
AEIR
  • AEIR
UBERON:0001045midgut
  • UBERON:0000066fully formed stage
  • UBERON:0000069larval stage
3.48e3
  • 3.48e3
  • 4.71e3
79.82
  • 79.82
  • 72.72
AEIR
  • AEIR
  • AEIR
FBbt:00003138adult midgut (Drosophila)
  • UBERON:0000066fully formed stage
3.67e3
  • 3.67e3
78.71
  • 78.71
AEIR
  • AEIR
UBERON:0001054Malpighian tubule
  • UBERON:0000066fully formed stage
  • UBERON:0000104life cycle
  • FBdv:00005341wandering third instar larval stage (Drosophila)
3.68e3
  • 3.68e3
  • 3.77e3
  • 5.23e3
78.68
  • 78.68
  • 78.17
  • 69.68
AEIR
  • AEIR
  • AEIR
  • AEIR
FBbt:00003133crop (Drosophila)
  • UBERON:0000066fully formed stage
3.79e3
  • 3.79e3
78.00
  • 78.00
AEIR
  • AEIR
FBbt:00001684embryonic/larval hemocyte (Drosophila)
  • FBdv:00005339third instar larval stage (Drosophila)
3.96e3
  • 3.96e3
77.04
  • 77.04
AEIR
  • AEIR
UBERON:0003917arthropod fat body
  • UBERON:0000066fully formed stage
  • FBdv:00005339third instar larval stage (Drosophila)
  • FBdv:00005341wandering third instar larval stage (Drosophila)
  • UBERON:0000069larval stage
  • UBERON:0004730instar larval stage
  • FBdv:00005343prepupal stage P1 (Drosophila)
  • FBdv:00005355pharate adult stage P8 (Drosophila)
4.45e3
  • 4.45e3
  • 4.54e3
  • 4.71e3
  • 5.69e3
  • 6.91e3
  • 6.97e3
  • 1.01e4
74.20
  • 74.20
  • 73.71
  • 72.68
  • 67.04
  • 59.93
  • 59.57
  • 41.43
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0013765digestive system element
  • FBdv:00005339third instar larval stage (Drosophila)
  • FBdv:00005341wandering third instar larval stage (Drosophila)
  • FBdv:00007095day 20 of adulthood (Drosophila)
  • FBdv:00007076day 1 of adulthood (Drosophila)
  • FBdv:00007079day 4 of adulthood (Drosophila)
4.45e3
  • 4.45e3
  • 4.94e3
  • 5.73e3
  • 5.85e3
  • 6.20e3
74.18
  • 74.18
  • 71.36
  • 66.81
  • 66.10
  • 64.05
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
FBbt:00004052thoracico-abdominal ganglion (Drosophila)
  • UBERON:0000066fully formed stage
4.96e3
  • 4.96e3
71.23
  • 71.23
AEIR
  • AEIR
FBbt:00003143adult hindgut (Drosophila)
  • UBERON:0000066fully formed stage
5.50e3
  • 5.50e3
68.09
  • 68.09
AEIR
  • AEIR
FBbt:00004514second segment of antenna (Drosophila)
  • UBERON:0000066fully formed stage
5.55e3
  • 5.55e3
67.83
  • 67.83
AEIR
  • AEIR
UBERON:0001044saliva-secreting gland
  • FBdv:00005343prepupal stage P1 (Drosophila)
  • FBdv:00005339third instar larval stage (Drosophila)
  • FBdv:00005341wandering third instar larval stage (Drosophila)
5.56e3
  • 5.56e3
  • 5.70e3
  • 6.06e3
67.75
  • 67.75
  • 66.96
  • 64.88
AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0003142prepupa
  • FBdv:00005343prepupal stage P1 (Drosophila)
  • FBdv:00005342prepupal stage (Drosophila)
5.80e3
  • 5.80e3
  • 6.84e3
66.36
  • 66.36
  • 60.37
AEIR
  • AEIR
  • AEIR
UBERON:0000992female gonad
  • FBdv:00007079day 4 of adulthood (Drosophila)
  • UBERON:0000066fully formed stage
6.22e3
  • 6.22e3
  • 6.84e3
63.97
  • 63.97
  • 60.37
AEIR
  • AEIR
  • AEIR
UBERON:0000955brain
  • UBERON:0000066fully formed stage
6.27e3
  • 6.27e3
63.67
  • 63.67
AEIR
  • AEIR
UBERON:0002548larva
  • FBdv:00007021third instar - cleared gut stage (Drosophila)
  • FBdv:00007019third instar - uncleared gut stage (Drosophila)
  • FBdv:00005338second instar larval stage (Drosophila)
  • FBdv:00007020third instar - partially cleared gut stage (Drosophila)
  • FBdv:00005339third instar larval stage (Drosophila)
  • FBdv:00005337first instar larval stage (Drosophila)
  • FBdv:00007005third instar larval stage L2 (Drosophila)
  • UBERON:0000069larval stage
  • FBdv:00005341wandering third instar larval stage (Drosophila)
  • FBdv:00007007late third instar larval stage (Drosophila)
  • FBdv:00005340early third instar larval stage (Drosophila)
  • UBERON:0004730instar larval stage
6.29e3
  • 6.29e3
  • 6.45e3
  • 6.55e3
  • 6.58e3
  • 6.89e3
  • 6.95e3
  • 7.54e3
  • 7.91e3
  • 8.07e3
  • 8.22e3
  • 8.24e3
  • 8.34e3
63.52
  • 63.52
  • 62.59
  • 62.02
  • 61.87
  • 60.03
  • 59.70
  • 56.30
  • 54.16
  • 53.20
  • 52.32
  • 52.25
  • 51.65
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
CL:0000025egg cell
  • FBdv:00005287unfertilized egg stage
6.32e3
  • 6.32e3
63.37
  • 63.37
AEIR
  • AEIR
UBERON:0007010cleaving embryo
  • UBERON:0000107cleavage stage
6.35e3
  • 6.35e3
63.19
  • 63.19
AEIR
  • AEIR
UBERON:0000033head
  • FBdv:00007095day 20 of adulthood (Drosophila)
  • FBdv:00007076day 1 of adulthood (Drosophila)
  • FBdv:00007083day 8 of adulthood (Drosophila)
  • FBdv:00007079day 4 of adulthood (Drosophila)
  • FBdv:00005364pharate adult stage P13 (Drosophila)
  • UBERON:0000104life cycle
  • UBERON:0000066fully formed stage
  • FBdv:00007085day 10 of adulthood (Drosophila)
  • FBdv:00007078day 3 of adulthood (Drosophila)
6.35e3
  • 6.35e3
  • 6.77e3
  • 6.81e3
  • 6.83e3
  • 7.16e3
  • 7.23e3
  • 7.60e3
  • 7.65e3
  • 7.79e3
63.18
  • 63.18
  • 60.75
  • 60.53
  • 60.40
  • 58.50
  • 58.06
  • 55.93
  • 55.63
  • 54.84
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
FBbt:00001778wing disc (Drosophila)
  • FBdv:00005339third instar larval stage (Drosophila)
6.62e3
  • 6.62e3
61.64
  • 61.64
AEIR
  • AEIR
UBERON:0003143pupa
  • FBdv:00005348prepupal stage P4(ii) (Drosophila)
  • FBdv:00005366pharate adult stage P15 (Drosophila)
  • FBdv:00005355pharate adult stage P8 (Drosophila)
  • FBdv:00005353pupal stage P6 (Drosophila)
  • FBdv:00005356pharate adult stage P9 (Drosophila)
  • UBERON:0000070pupal stage
6.68e3
  • 6.68e3
  • 8.15e3
  • 8.34e3
  • 8.83e3
  • 9.66e3
  • 1.01e4
61.28
  • 61.28
  • 52.75
  • 51.64
  • 48.80
  • 44.01
  • 41.41
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0000994spermathecum
  • UBERON:0000066fully formed stage
6.73e3
  • 6.73e3
61.00
  • 61.00
AEIR
  • AEIR
UBERON:0003153head capsule
  • UBERON:0000066fully formed stage
6.86e3
  • 6.86e3
60.26
  • 60.26
AEIR
  • AEIR
FBbt:00005725adult Malpighian tubule (Drosophila)
  • UBERON:0000066fully formed stage
6.89e3
  • 6.89e3
60.05
  • 60.05
AEIR
  • AEIR
CL:0000655secondary oocyte
  • FBdv:00005283oogenesis stage S14
6.93e3
  • 6.93e3
59.81
  • 59.81
AEIR
  • AEIR
CL:0000023oocyte
  • UBERON:0000066fully formed stage
6.96e3
  • 6.96e3
59.64
  • 59.64
AEIR
  • AEIR
FBbt:00001768eye disc (Drosophila)
  • FBdv:00005339third instar larval stage (Drosophila)
7.01e3
  • 7.01e3
59.37
  • 59.37
AEIR
  • AEIR
UBERON:0001017central nervous system
  • FBdv:00005339third instar larval stage (Drosophila)
  • FBdv:00005355pharate adult stage P8 (Drosophila)
7.06e3
  • 7.06e3
  • 7.18e3
59.07
  • 59.07
  • 58.40
AEIR
  • AEIR
  • AEIR
UBERON:0007023adult organism
  • FBdv:00005343prepupal stage P1 (Drosophila)
  • FBdv:00007105day 30 of adulthood (Drosophila)
  • FBdv:00007080day 5 of adulthood (Drosophila)
  • FBdv:00007076day 1 of adulthood (Drosophila)
  • UBERON:0000066fully formed stage
  • FBdv:00007078day 3 of adulthood (Drosophila)
  • FBdv:00007092day 17 of adulthood (Drosophila)
7.36e3
  • 7.36e3
  • 7.77e3
  • 8.16e3
  • 8.24e3
  • 8.26e3
  • 8.99e3
  • 9.80e3
57.32
  • 57.32
  • 54.98
  • 52.70
  • 52.25
  • 52.12
  • 47.86
  • 43.21
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
FBbt:00003023adult abdomen (Drosophila)
  • UBERON:0000066fully formed stage
7.52e3
  • 7.52e3
56.40
  • 56.40
AEIR
  • AEIR
UBERON:0000939imaginal disc
  • FBdv:00005339third instar larval stage (Drosophila)
  • FBdv:00005341wandering third instar larval stage (Drosophila)
7.55e3
  • 7.55e3
  • 9.09e3
56.24
  • 56.24
  • 47.28
AEIR
  • AEIR
  • AEIR
UBERON:0006868seminal fluid secreting gland
  • UBERON:0000066fully formed stage
7.84e3
  • 7.84e3
54.58
  • 54.58
AEIR
  • AEIR
UBERON:0000468multi-cellular organism
  • UBERON:0000092post-embryonic stage
  • FBdv:00005301embryonic stage 3 (Drosophila)
  • FBdv:00005291embryonic stage 1 (Drosophila)
  • FBdv:00005293embryonic stage 2 (Drosophila)
8.49e3
  • 8.49e3
  • 8.63e3
  • 8.63e3
  • 8.63e3
50.78
  • 50.78
  • 49.99
  • 49.99
  • 49.99
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
FBbt:00000057yolk nucleus (Drosophila)
  • FBdv:00005318embryonic stage 6 (Drosophila)
  • FBdv:00005319embryonic stage 7 (Drosophila)
  • FBdv:00005322embryonic stage 8 (Drosophila)
  • FBdv:00005323embryonic stage 9 (Drosophila)
  • FBdv:00005324embryonic stage 10 (Drosophila)
  • FBdv:00005306embryonic stage 4 (Drosophila)
  • FBdv:00005311embryonic stage 5 (Drosophila)
  • FBdv:00005325embryonic stage 11 (Drosophila)
  • FBdv:00005327embryonic stage 12 (Drosophila)
8.62e3
  • 8.62e3
  • 8.62e3
  • 8.62e3
  • 8.62e3
  • 8.62e3
  • 8.63e3
  • 8.63e3
  • 8.63e3
  • 8.63e3
50.00
  • 50.00
  • 50.00
  • 50.00
  • 50.00
  • 50.00
  • 50.00
  • 50.00
  • 50.00
  • 50.00
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
FBbt:00000210anterior endoderm anlage (Drosophila)
  • FBdv:00005319embryonic stage 7 (Drosophila)
  • FBdv:00005322embryonic stage 8 (Drosophila)
8.62e3
  • 8.62e3
  • 8.62e3
50.00
  • 50.00
  • 50.00
AEIR
  • AEIR
  • AEIR
FBbt:00017006plasmatocyte primordium (Drosophila)
  • FBdv:00005325embryonic stage 11 (Drosophila)
  • FBdv:00005327embryonic stage 12 (Drosophila)
8.62e3
  • 8.62e3
  • 8.62e3
50.00
  • 50.00
  • 50.00
AEIR
  • AEIR
  • AEIR
FBbt:00000127head mesoderm (Drosophila)
  • FBdv:00005319embryonic stage 7 (Drosophila)
  • FBdv:00005322embryonic stage 8 (Drosophila)
  • FBdv:00005323embryonic stage 9 (Drosophila)
  • FBdv:00005324embryonic stage 10 (Drosophila)
8.63e3
  • 8.63e3
  • 8.63e3
  • 8.63e3
  • 8.63e3
50.00
  • 50.00
  • 50.00
  • 50.00
  • 50.00
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
FBbt:00000128trunk mesoderm (Drosophila)
  • FBdv:00005319embryonic stage 7 (Drosophila)
  • FBdv:00005322embryonic stage 8 (Drosophila)
  • FBdv:00005323embryonic stage 9 (Drosophila)
  • FBdv:00005324embryonic stage 10 (Drosophila)
8.63e3
  • 8.63e3
  • 8.63e3
  • 8.63e3
  • 8.63e3
50.00
  • 50.00
  • 50.00
  • 50.00
  • 50.00
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
FBbt:00005559anterior endoderm (Drosophila)
  • FBdv:00005323embryonic stage 9 (Drosophila)
  • FBdv:00005324embryonic stage 10 (Drosophila)
8.63e3
  • 8.63e3
  • 8.63e3
50.00
  • 50.00
  • 50.00
AEIR
  • AEIR
  • AEIR
FBbt:00005560posterior endoderm (Drosophila)
  • FBdv:00005319embryonic stage 7 (Drosophila)
  • FBdv:00005322embryonic stage 8 (Drosophila)
  • FBdv:00005323embryonic stage 9 (Drosophila)
  • FBdv:00005324embryonic stage 10 (Drosophila)
8.63e3
  • 8.63e3
  • 8.63e3
  • 8.63e3
  • 8.63e3
50.00
  • 50.00
  • 50.00
  • 50.00
  • 50.00
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
UBERON:0010302amnioserosa
  • FBdv:00005328embryonic stage 13 (Drosophila)
  • FBdv:00005330embryonic stage 14 (Drosophila)
  • FBdv:00005332embryonic stage 15 (Drosophila)
  • FBdv:00005334embryonic stage 16 (Drosophila)
8.63e3
  • 8.63e3
  • 8.63e3
  • 8.63e3
  • 8.63e3
50.00
  • 50.00
  • 50.00
  • 50.00
  • 50.00
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
FBbt:00001882embryonic/larval midgut (Drosophila)
  • FBdv:00005328embryonic stage 13 (Drosophila)
  • FBdv:00005330embryonic stage 14 (Drosophila)
  • FBdv:00005332embryonic stage 15 (Drosophila)
  • FBdv:00005334embryonic stage 16 (Drosophila)
8.63e3
  • 8.63e3
  • 8.63e3
  • 8.63e3
  • 8.63e3
50.00
  • 50.00
  • 50.00
  • 50.00
  • 50.00
AEIR
  • AEIR
  • AEIR
  • AEIR
  • AEIR
FBbt:00000444anterior midgut primordium (Drosophila)
  • FBdv:00005325embryonic stage 11 (Drosophila)
  • FBdv:00005327embryonic stage 12 (Drosophila)
8.63e3
  • 8.63e3
  • 8.63e3
49.99
  • 49.99
  • 49.99
AEIR
  • AEIR
  • AEIR
FBbt:10005329posterior midgut primordium (Drosophila)
  • FBdv:00005325embryonic stage 11 (Drosophila)
  • FBdv:00005327embryonic stage 12 (Drosophila)
8.63e3
  • 8.63e3
  • 8.63e3
49.99
  • 49.99
  • 49.99
AEIR
  • AEIR
  • AEIR
UBERON:0000473testis
  • UBERON:0000066fully formed stage
  • FBdv:00007079day 4 of adulthood (Drosophila)
8.95e3
  • 8.95e3
  • 1.10e4
48.10
  • 48.10
  • 36.08
AEIR
  • AEIR
  • AEIR
UBERON:0005399male reproductive gland
  • FBdv:00007079day 4 of adulthood (Drosophila)
1.11e4
  • 1.11e4
35.52
  • 35.52
AEIR
  • AEIR
Sources
AAffymetrix
EEST
IIn Situ
RRNA-Seq
data
no data
Rank scores
3.25e4lightgrey: low confidence scores

important score variation

Rank scores of expression calls are normalized across genes, conditions and species. Low score means that the gene is highly expressed in the condition. Max rank score in all species: 4.10e4. Min rank score varies across species.

Expression scores of expression calls use the minimum and maximum Rank of the species to normalize the expression to a value between 0 and 100. Low score means that the gene is lowly expressed in the condition.

Sources of annotations to anatomy and development:
Sources of raw data:

Orthologs

Taxon nameSpecies with orthologsGene(s)Expression comparisonSee details
melanogaster subgroup2 species2 genesCompare expression
melanogaster group3 species3 genesCompare expression
Drosophila5 species5 genesCompare expression
Bilateria24 species24 genesCompare expression

Orthology information comes from OMA : FBgn0038475.

Paralogs (same species)

Taxon nameGene(s)Expression comparisonSee details
Eukaryota5 genesCompare expression

Paralogy information comes from OMA : FBgn0038475.

Cross-references

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