Bgee is a database to retrieve and compare gene expression patterns in multiple animal species, produced from multiple data types (RNA-Seq, Affymetrix, in situ hybridization, and EST data) and from multiple data sets (including GTEx data).
Bgee is based exclusively on curated "normal", healthy, expression data (e.g., no gene knock-out, no treatment, no disease), to provide a comparable reference of normal gene expression.
Bgee produces calls of presence/absence of expression, and of differential over-/under-expression, integrated along with information of gene orthology, and of homology between organs. This allows comparisons of expression patterns between species.
This is an incremental update of Bgee, with an updated RNA-Seq dataset, using the same genomes and ontologies as for the previous version Bgee 14.0. New RNA-Seq libraries have been added; some libraries previously integrated in Bgee have been discarded following corrections and improvements of quality controls. The Affymetrix, in situ hybridization, and EST datasets, are the same as for the previous release of Bgee 14.0. All calls of presence/absence of expression, expression scores, and all the Bgee tools and download files, have been updated accordingly.
For most species in Bgee, notably non-human primates and farm and domestic animals, this represents a major improvement of the anatomy and life stage coverage of the data, making all Bgee tools much more useful, notably TopAnat and the gene pages.
You can still access Bgee version 14.0 at https://bgee.org/bgee14.
Images from Wikimedia Commons. In most cases, pictures corresponds to the sequenced strains. Show information about original images.
Homo sapiens picture by Leonardo da Vinci (Life time: 1519) [Public domain]. See H. sapiens picture via Wikimedia Commons
Danio rerio picture by Azul (Own work) [see page for license], See D. rerio picture via Wikimedia Commons
Bos taurus picture by User Robert Merkel on en.wikipedia (US Department of Agriculture) [Public domain], See B. taurus picture via Wikimedia Commons
Sus scrofa picture by Joshua Lutz (Own work) [Public domain], See S. scrofa picture via Wikimedia Commons
Equus caballus picture by Doug Antczak Baker Institute for Animal Health College of Veterinary Medicine Cornell University [Public Domain], See E. caballus picture via Wikimedia Commons
Canis lupus familiaris picture by Mood210 (Own work) [CC-BY-SA-3.0], See C. lupus familiaris picture via Wikimedia Commons
Monodelphis domestica picture by Marsupial Genome Sheds Light on the Evolution of Immunity. Hill E, PLoS Biology Vol. 4/3/2006, e75 http://dx.doi.org/10.1371/journal.pbio.0040075 [CC-BY-2.5], See M. domestica picture via Wikimedia Commons
Drosophila ananassae picture by Nicolas Gompel [CC BY-NC-SA 2.0 FR], See D. ananassae picture via Nicolas Gompel's lab website
Drosophila mojavensis picture by Nicolas Gompel [CC BY-NC-SA 2.0 FR], See D. mojavensis picture via Nicolas Gompel's lab website
Drosophila pseudoobscura picture, See D. pseudoobscura picture via Ensembl Metazoa
Drosophila simulans picture by Nicolas Gompel [CC BY-NC-SA 2.0 FR], See D. simulans picture via Nicolas Gompel's lab website
Drosophila virilis picture by Nicolas Gompel [CC BY-NC-SA 2.0 FR], See D. virilis picture via Nicolas Gompel's lab website
Drosophila yakuba picture by Nicolas Gompel [CC BY-NC-SA 2.0 FR], See D. yakuba picture via Nicolas Gompel's lab website