Search Genes

Gene : SIRT3 - ENSG00000142082 - Homo sapiens (human)

General information

Expressed in right frontal lobe and 192 other cell types or tissues.

Gene identifier

ENSG00000142082

Name

SIRT3

Description

sirtuin 3 [Source:HGNC Symbol;Acc:HGNC:14931]

Organism

Homo sapiens (human)

Synonym(s)

sir2l3

Orthologs

42 orthologs

Paralogs

5 paralogs

Source data

Retrieve all processed expression values for that gene

Expression graph

80%

Expression table

80%

Reported absence of expression

80%

Orthologs

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Taxon Name	Species with orthologs	Gene(s)	Expression comparison
Homininae	3 species Gorilla gorilla (gorilla) Pan paniscus (bonobo) Pan troglodytes (chimpanzee)	3 genes ENSGGOG00000013147 SIRT3 ENSPPAG00000034226 SIRT3 ENSPTRG00000045471 SIRT3	Compare expression
Catarrhini	9 species Cercocebus atys (Sooty mangabey) Macaca fascicularis (Crab-eating macaque) Macaca mulatta (macaque) Macaca nemestrina (Pig-tailed macaque) Papio anubis (Olive baboon) Gorilla gorilla (gorilla) Pan paniscus (bonobo) Pan troglodytes (chimpanzee) Chlorocebus sabaeus (Green monkey)	9 genes ENSCATG00000042951 SIRT3 ENSMFAG00000041754 SIRT3 ENSMMUG00000008490 SIRT3 ENSMNEG00000036819 SIRT3 ENSPANG00000008375 SIRT3 ENSGGOG00000013147 SIRT3 ENSPPAG00000034226 SIRT3 ENSPTRG00000045471 SIRT3 ENSCSAG00000011291 SIRT3	Compare expression
Simiiformes	10 species Callithrix jacchus (White-tufted-ear marmoset) Cercocebus atys (Sooty mangabey) Macaca fascicularis (Crab-eating macaque) Macaca mulatta (macaque) Macaca nemestrina (Pig-tailed macaque) Papio anubis (Olive baboon) Gorilla gorilla (gorilla) Pan paniscus (bonobo) Pan troglodytes (chimpanzee) Chlorocebus sabaeus (Green monkey)	10 genes ENSCJAG00000005639 SIRT3 ENSCATG00000042951 SIRT3 ENSMFAG00000041754 SIRT3 ENSMMUG00000008490 SIRT3 ENSMNEG00000036819 SIRT3 ENSPANG00000008375 SIRT3 ENSGGOG00000013147 SIRT3 ENSPPAG00000034226 SIRT3 ENSPTRG00000045471 SIRT3 ENSCSAG00000011291 SIRT3	Compare expression
Primates	11 species Callithrix jacchus (White-tufted-ear marmoset) Cercocebus atys (Sooty mangabey) Macaca fascicularis (Crab-eating macaque) Macaca mulatta (macaque) Macaca nemestrina (Pig-tailed macaque) Papio anubis (Olive baboon) Gorilla gorilla (gorilla) Pan paniscus (bonobo) Pan troglodytes (chimpanzee) Microcebus murinus (Gray mouse lemur) Chlorocebus sabaeus (Green monkey)	11 genes ENSCJAG00000005639 SIRT3 ENSCATG00000042951 SIRT3 ENSMFAG00000041754 SIRT3 ENSMMUG00000008490 SIRT3 ENSMNEG00000036819 SIRT3 ENSPANG00000008375 SIRT3 ENSGGOG00000013147 SIRT3 ENSPPAG00000034226 SIRT3 ENSPTRG00000045471 SIRT3 ENSMICG00000006303 SIRT3 ENSCSAG00000011291 SIRT3	Compare expression
Euarchontoglires	15 species Mus musculus (mouse) Oryctolagus cuniculus (rabbit) Cavia porcellus (guinea pig) Callithrix jacchus (White-tufted-ear marmoset) Cercocebus atys (Sooty mangabey) Macaca fascicularis (Crab-eating macaque) Macaca mulatta (macaque) Macaca nemestrina (Pig-tailed macaque) Papio anubis (Olive baboon) Gorilla gorilla (gorilla) Pan paniscus (bonobo) Pan troglodytes (chimpanzee) Microcebus murinus (Gray mouse lemur) Chlorocebus sabaeus (Green monkey) Rattus norvegicus (rat)	15 genes ENSMUSG00000025486 Sirt3 ENSOCUG00000025521 SIRT3 ENSCPOG00000023769 SIRT3 ENSCJAG00000005639 SIRT3 ENSCATG00000042951 SIRT3 ENSMFAG00000041754 SIRT3 ENSMMUG00000008490 SIRT3 ENSMNEG00000036819 SIRT3 ENSPANG00000008375 SIRT3 ENSGGOG00000013147 SIRT3 ENSPPAG00000034226 SIRT3 ENSPTRG00000045471 SIRT3 ENSMICG00000006303 SIRT3 ENSCSAG00000011291 SIRT3 ENSRNOG00000013828 Sirt3	Compare expression
Boreoeutheria	23 species Mus musculus (mouse) Canis lupus familiaris (dog) Felis catus (cat) Equus caballus (horse) Sus scrofa (pig) Bos taurus (cattle) Capra hircus (Goat) Ovis aries (Sheep) Oryctolagus cuniculus (rabbit) Cavia porcellus (guinea pig) Callithrix jacchus (White-tufted-ear marmoset) Cercocebus atys (Sooty mangabey) Macaca fascicularis (Crab-eating macaque) Macaca mulatta (macaque) Macaca nemestrina (Pig-tailed macaque) Papio anubis (Olive baboon) Gorilla gorilla (gorilla) Pan paniscus (bonobo) Pan troglodytes (chimpanzee) Microcebus murinus (Gray mouse lemur) Chlorocebus sabaeus (Green monkey) Manis javanica (Malayan pangolin) Rattus norvegicus (rat)	23 genes ENSMUSG00000025486 Sirt3 ENSCAFG00000006450 SIRT3 ENSFCAG00000002668 SIRT3 ENSECAG00000003330 SIRT3 ENSSSCG00000014558 SIRT3 ENSBTAG00000002044 SIRT3 ENSCHIG00000015340 SIRT3 ENSOARG00000008832 SIRT3 ENSOCUG00000025521 SIRT3 ENSCPOG00000023769 SIRT3 ENSCJAG00000005639 SIRT3 ENSCATG00000042951 SIRT3 ENSMFAG00000041754 SIRT3 ENSMMUG00000008490 SIRT3 ENSMNEG00000036819 SIRT3 ENSPANG00000008375 SIRT3 ENSGGOG00000013147 SIRT3 ENSPPAG00000034226 SIRT3 ENSPTRG00000045471 SIRT3 ENSMICG00000006303 SIRT3 ENSCSAG00000011291 SIRT3 108384848 SIRT3 ENSRNOG00000013828 Sirt3	Compare expression
Theria	24 species Mus musculus (mouse) Canis lupus familiaris (dog) Felis catus (cat) Equus caballus (horse) Sus scrofa (pig) Bos taurus (cattle) Capra hircus (Goat) Ovis aries (Sheep) Oryctolagus cuniculus (rabbit) Cavia porcellus (guinea pig) Callithrix jacchus (White-tufted-ear marmoset) Cercocebus atys (Sooty mangabey) Macaca fascicularis (Crab-eating macaque) Macaca mulatta (macaque) Macaca nemestrina (Pig-tailed macaque) Papio anubis (Olive baboon) Gorilla gorilla (gorilla) Pan paniscus (bonobo) Pan troglodytes (chimpanzee) Microcebus murinus (Gray mouse lemur) Chlorocebus sabaeus (Green monkey) Manis javanica (Malayan pangolin) Rattus norvegicus (rat) Monodelphis domestica (opossum)	24 genes ENSMUSG00000025486 Sirt3 ENSCAFG00000006450 SIRT3 ENSFCAG00000002668 SIRT3 ENSECAG00000003330 SIRT3 ENSSSCG00000014558 SIRT3 ENSBTAG00000002044 SIRT3 ENSCHIG00000015340 SIRT3 ENSOARG00000008832 SIRT3 ENSOCUG00000025521 SIRT3 ENSCPOG00000023769 SIRT3 ENSCJAG00000005639 SIRT3 ENSCATG00000042951 SIRT3 ENSMFAG00000041754 SIRT3 ENSMMUG00000008490 SIRT3 ENSMNEG00000036819 SIRT3 ENSPANG00000008375 SIRT3 ENSGGOG00000013147 SIRT3 ENSPPAG00000034226 SIRT3 ENSPTRG00000045471 SIRT3 ENSMICG00000006303 SIRT3 ENSCSAG00000011291 SIRT3 108384848 SIRT3 ENSRNOG00000013828 Sirt3 ENSMODG00000021183 SIRT3	Compare expression
Amniota	27 species Mus musculus (mouse) Canis lupus familiaris (dog) Felis catus (cat) Equus caballus (horse) Sus scrofa (pig) Bos taurus (cattle) Capra hircus (Goat) Ovis aries (Sheep) Oryctolagus cuniculus (rabbit) Cavia porcellus (guinea pig) Gallus gallus (chicken) Meleagris gallopavo (Wild turkey) Callithrix jacchus (White-tufted-ear marmoset) Cercocebus atys (Sooty mangabey) Macaca fascicularis (Crab-eating macaque) Macaca mulatta (macaque) Macaca nemestrina (Pig-tailed macaque) Papio anubis (Olive baboon) Gorilla gorilla (gorilla) Pan paniscus (bonobo) Pan troglodytes (chimpanzee) Microcebus murinus (Gray mouse lemur) Chlorocebus sabaeus (Green monkey) Manis javanica (Malayan pangolin) Rattus norvegicus (rat) Monodelphis domestica (opossum) Anolis carolinensis (green anole)	27 genes ENSMUSG00000025486 Sirt3 ENSCAFG00000006450 SIRT3 ENSFCAG00000002668 SIRT3 ENSECAG00000003330 SIRT3 ENSSSCG00000014558 SIRT3 ENSBTAG00000002044 SIRT3 ENSCHIG00000015340 SIRT3 ENSOARG00000008832 SIRT3 ENSOCUG00000025521 SIRT3 ENSCPOG00000023769 SIRT3 ENSGALG00000032496 SIRT3 ENSMGAG00000002457 SIRT3 ENSCJAG00000005639 SIRT3 ENSCATG00000042951 SIRT3 ENSMFAG00000041754 SIRT3 ENSMMUG00000008490 SIRT3 ENSMNEG00000036819 SIRT3 ENSPANG00000008375 SIRT3 ENSGGOG00000013147 SIRT3 ENSPPAG00000034226 SIRT3 ENSPTRG00000045471 SIRT3 ENSMICG00000006303 SIRT3 ENSCSAG00000011291 SIRT3 108384848 SIRT3 ENSRNOG00000013828 Sirt3 ENSMODG00000021183 SIRT3 ENSACAG00000017510 SIRT3	Compare expression
Tetrapoda	28 species Mus musculus (mouse) Canis lupus familiaris (dog) Felis catus (cat) Equus caballus (horse) Sus scrofa (pig) Bos taurus (cattle) Capra hircus (Goat) Ovis aries (Sheep) Oryctolagus cuniculus (rabbit) Cavia porcellus (guinea pig) Gallus gallus (chicken) Meleagris gallopavo (Wild turkey) Callithrix jacchus (White-tufted-ear marmoset) Cercocebus atys (Sooty mangabey) Macaca fascicularis (Crab-eating macaque) Macaca mulatta (macaque) Macaca nemestrina (Pig-tailed macaque) Papio anubis (Olive baboon) Gorilla gorilla (gorilla) Pan paniscus (bonobo) Pan troglodytes (chimpanzee) Microcebus murinus (Gray mouse lemur) Chlorocebus sabaeus (Green monkey) Manis javanica (Malayan pangolin) Rattus norvegicus (rat) Monodelphis domestica (opossum) Xenopus laevis (African clawed frog) Anolis carolinensis (green anole)	28 genes ENSMUSG00000025486 Sirt3 ENSCAFG00000006450 SIRT3 ENSFCAG00000002668 SIRT3 ENSECAG00000003330 SIRT3 ENSSSCG00000014558 SIRT3 ENSBTAG00000002044 SIRT3 ENSCHIG00000015340 SIRT3 ENSOARG00000008832 SIRT3 ENSOCUG00000025521 SIRT3 ENSCPOG00000023769 SIRT3 ENSGALG00000032496 SIRT3 ENSMGAG00000002457 SIRT3 ENSCJAG00000005639 SIRT3 ENSCATG00000042951 SIRT3 ENSMFAG00000041754 SIRT3 ENSMMUG00000008490 SIRT3 ENSMNEG00000036819 SIRT3 ENSPANG00000008375 SIRT3 ENSGGOG00000013147 SIRT3 ENSPPAG00000034226 SIRT3 ENSPTRG00000045471 SIRT3 ENSMICG00000006303 SIRT3 ENSCSAG00000011291 SIRT3 108384848 SIRT3 ENSRNOG00000013828 Sirt3 ENSMODG00000021183 SIRT3 108715195 sirt3.1.S ENSACAG00000017510 SIRT3	Compare expression
Sarcopterygii	29 species Mus musculus (mouse) Canis lupus familiaris (dog) Felis catus (cat) Equus caballus (horse) Sus scrofa (pig) Bos taurus (cattle) Capra hircus (Goat) Ovis aries (Sheep) Oryctolagus cuniculus (rabbit) Cavia porcellus (guinea pig) Gallus gallus (chicken) Meleagris gallopavo (Wild turkey) Callithrix jacchus (White-tufted-ear marmoset) Cercocebus atys (Sooty mangabey) Macaca fascicularis (Crab-eating macaque) Macaca mulatta (macaque) Macaca nemestrina (Pig-tailed macaque) Papio anubis (Olive baboon) Gorilla gorilla (gorilla) Pan paniscus (bonobo) Pan troglodytes (chimpanzee) Microcebus murinus (Gray mouse lemur) Chlorocebus sabaeus (Green monkey) Manis javanica (Malayan pangolin) Rattus norvegicus (rat) Monodelphis domestica (opossum) Xenopus laevis (African clawed frog) Anolis carolinensis (green anole) Latimeria chalumnae (Coelacanth)	29 genes ENSMUSG00000025486 Sirt3 ENSCAFG00000006450 SIRT3 ENSFCAG00000002668 SIRT3 ENSECAG00000003330 SIRT3 ENSSSCG00000014558 SIRT3 ENSBTAG00000002044 SIRT3 ENSCHIG00000015340 SIRT3 ENSOARG00000008832 SIRT3 ENSOCUG00000025521 SIRT3 ENSCPOG00000023769 SIRT3 ENSGALG00000032496 SIRT3 ENSMGAG00000002457 SIRT3 ENSCJAG00000005639 SIRT3 ENSCATG00000042951 SIRT3 ENSMFAG00000041754 SIRT3 ENSMMUG00000008490 SIRT3 ENSMNEG00000036819 SIRT3 ENSPANG00000008375 SIRT3 ENSGGOG00000013147 SIRT3 ENSPPAG00000034226 SIRT3 ENSPTRG00000045471 SIRT3 ENSMICG00000006303 SIRT3 ENSCSAG00000011291 SIRT3 108384848 SIRT3 ENSRNOG00000013828 Sirt3 ENSMODG00000021183 SIRT3 108715195 sirt3.1.S ENSACAG00000017510 SIRT3 ENSLACG00000005920 SIRT3	Compare expression
Euteleostomi	41 species Mus musculus (mouse) Danio rerio (zebrafish) Canis lupus familiaris (dog) Felis catus (cat) Equus caballus (horse) Sus scrofa (pig) Bos taurus (cattle) Capra hircus (Goat) Ovis aries (Sheep) Oryctolagus cuniculus (rabbit) Cavia porcellus (guinea pig) Gallus gallus (chicken) Meleagris gallopavo (Wild turkey) Callithrix jacchus (White-tufted-ear marmoset) Cercocebus atys (Sooty mangabey) Macaca fascicularis (Crab-eating macaque) Macaca mulatta (macaque) Macaca nemestrina (Pig-tailed macaque) Papio anubis (Olive baboon) Gorilla gorilla (gorilla) Pan paniscus (bonobo) Pan troglodytes (chimpanzee) Microcebus murinus (Gray mouse lemur) Chlorocebus sabaeus (Green monkey) Manis javanica (Malayan pangolin) Rattus norvegicus (rat) Monodelphis domestica (opossum) Xenopus laevis (African clawed frog) Anolis carolinensis (green anole) Lepisosteus oculatus (Spotted gar) Anguilla anguilla (European freshwater eel) Astyanax mexicanus (Blind cave fish) Esox lucius (Northern pike) Salmo salar (Atlantic salmon) Gadus morhua (Atlantic cod) Oryzias latipes (Japanese rice fish) Astatotilapia calliptera (Eastern happy) Neolamprologus brichardi (Fairy cichlid) Gasterosteus aculeatus (Three-spined stickleback) Nothobranchius furzeri (Turquoise killifish) Latimeria chalumnae (Coelacanth)	42 genes ENSMUSG00000025486 Sirt3 ENSDARG00000035819 sirt3 ENSCAFG00000006450 SIRT3 ENSFCAG00000002668 SIRT3 ENSECAG00000003330 SIRT3 ENSSSCG00000014558 SIRT3 ENSBTAG00000002044 SIRT3 ENSCHIG00000015340 SIRT3 ENSOARG00000008832 SIRT3 ENSOCUG00000025521 SIRT3 ENSCPOG00000023769 SIRT3 ENSGALG00000032496 SIRT3 ENSMGAG00000002457 SIRT3 ENSCJAG00000005639 SIRT3 ENSCATG00000042951 SIRT3 ENSMFAG00000041754 SIRT3 ENSMMUG00000008490 SIRT3 ENSMNEG00000036819 SIRT3 ENSPANG00000008375 SIRT3 ENSGGOG00000013147 SIRT3 ENSPPAG00000034226 SIRT3 ENSPTRG00000045471 SIRT3 ENSMICG00000006303 SIRT3 ENSCSAG00000011291 SIRT3 108384848 SIRT3 ENSRNOG00000013828 Sirt3 ENSMODG00000021183 SIRT3 108715195 sirt3.1.S ENSACAG00000017510 SIRT3 ENSLOCG00000002426 sirt3 118215292 sirt3 ENSAMXG00000007187 sirt3 ENSELUG00000018526 sirt3 ENSSSAG00000009832 sirt3 ENSSSAG00000058230 sirt3 ENSGMOG00000007852 sirt3 ENSORLG00000000086 sirt3 ENSACLG00000005978 sirt3 ENSNBRG00000015268 sirt3 ENSGACG00000015722 sirt3 ENSNFUG00015010188 SIRT3 ENSLACG00000005920 SIRT3	Compare expression

Showing 1 to 11 of 11 entries

Orthology information comes from OMA : ENSG00000142082.

Paralogs (same species)

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Taxon Name	Gene(s)	Expression comparison	See details
Bilateria	1 gene ENSG00000068903 SIRT2	Compare expression: table \| graph
Opisthokonta	5 genes ENSG00000068903 SIRT2 ENSG00000077463 SIRT6 ENSG00000089163 SIRT4 ENSG00000124523 SIRT5 ENSG00000187531 SIRT7	Compare expression: table \| graph

Showing 1 to 2 of 2 entries

Paralogy information comes from OMA : ENSG00000142082.

Cross-references

CCDS

CCDS53590 (CCDS53590.1),CCDS7691 (CCDS7691.1)

Ensembl

ENSG00000142082 (SIRT3)

HGNC

HGNC:14931 (SIRT3)

EMBL

AC069287,AC136475,AF083108,AK299438,AL137276,BC001042

GeneCards

ENSG00000142082

UniProtKB/Swiss-Prot

Q9NTG7,SIR3_HUMAN

UniProtKB/TrEMBL

B7WNN4,B7WNN4_HUMAN,E9PIT6,E9PIT6_HUMAN,E9PJS6,E9PJS6_HUMAN,E9PK80,E9PK80_HUMAN