Search Genes

Gene : BRCA2 - ENSG00000139618 - Homo sapiens (human)

General information

Gene identifier

ENSG00000139618

Name

BRCA2

Description

BRCA2 DNA repair associated [Source:HGNC Symbol;Acc:HGNC:1101]

Organism

Homo sapiens (human)

Synonym(s)

xrcc11,facd,fancd1,fad1,brcc2,fad,fancd

Orthologs

26 orthologs

Source data

Retrieve all processed expression values for that gene

Expression

80%

Reported absence of expression

Anat. entity and cell typesDev. stageSexStrain

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entries

Anatomical entity	Expression score	FDR	Link to source data	Sources
CL:0000019sperm	38.32	0.84	See source data	RSCAIE
UBERON:0001782pigmented layer of retina	38.55	0.547	See source data	RSCAIE
UBERON:0002771middle temporal gyrus	38.72	0.625	See source data	RSCAIE
UBERON:0004358caput epididymis	38.75	0.954	See source data	RSCAIE
UBERON:0000998seminal vesicle	38.75	0.984	See source data	RSCAIE
UBERON:0002476lateral globus pallidus	38.81	0.876	See source data	RSCAIE
UBERON:0002736lateral nuclear group of thalamus	39.00	0.893	See source data	RSCAIE
UBERON:0002728entorhinal cortex	39.05	0.998	See source data	RSCAIE
UBERON:0001966substantia nigra pars reticulata	39.11	0.876	See source data	RSCAIE
UBERON:0002477medial globus pallidus	39.18	0.657	See source data	RSCAIE
UBERON:0011876body of tongue	39.22	0.969	See source data	RSCAIE
UBERON:0002581postcentral gyrus	39.23	0.998	See source data	RSCAIE
UBERON:0001965substantia nigra pars compacta	39.23	0.975	See source data	RSCAIE
UBERON:0000355pharyngeal mucosa	39.27	0.748	See source data	RSCAIE
UBERON:0004087vena cava	39.31	0.909	See source data	RSCAIE
UBERON:0002691ventral tegmental area	39.35	0.992	See source data	RSCAIE
UBERON:0001906subthalamic nucleus	39.35	0.99	See source data	RSCAIE
UBERON:0013554Brodmann (1909) area 23	39.40	0.998	See source data	RSCAIE
UBERON:0001162cardia of stomach	39.46	0.958	See source data	RSCAIE
UBERON:0007227superior vestibular nucleus	39.47	0.975	See source data	RSCAIE

Showing 1 to 20 of 86 entries

Sources

A Affimetrix

E EST

I In Situ

R RNA-Seq

SC scRNA-Seq

datano data

Expression scores

3.25e4 lightgrey: low confidence scores

important score variation

Expression scores of expression calls is based on the rank of a gene in a condition according to its expression levels (non-parametric statistics), normalized using the minimum and maximum Rank of the species. Values of Expression scores are between 0 and 100. Low score means that the gene is lowly expressed in the condition compared to other genes. Scores are normalized and comparable across genes, conditions and species.

Sources of annotations to anatomy and development:

Affymetrix data: Bgee

Sources of raw data:

Affymetrix data: ArrayExpress, GEO

Orthologs

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Taxon Name	Species with orthologs	Gene(s)	Expression comparison
Homininae	3 species Gorilla gorilla (gorilla) Pan paniscus (bonobo) Pan troglodytes (chimpanzee)	3 genes ENSGGOG00000015808 BRCA2 ENSPPAG00000002166 BRCA2 ENSPTRG00000005766 BRCA2	Compare expression
Catarrhini	9 species Cercocebus atys (Sooty mangabey) Macaca fascicularis (Crab-eating macaque) Macaca mulatta (macaque) Macaca nemestrina (Pig-tailed macaque) Papio anubis (Olive baboon) Gorilla gorilla (gorilla) Pan paniscus (bonobo) Pan troglodytes (chimpanzee) Chlorocebus sabaeus (Green monkey)	9 genes ENSCATG00000031672 BRCA2 ENSMFAG00000041961 BRCA2 ENSMMUG00000007197 BRCA2 ENSMNEG00000036002 BRCA2 ENSPANG00000013323 BRCA2 ENSGGOG00000015808 BRCA2 ENSPPAG00000002166 BRCA2 ENSPTRG00000005766 BRCA2 ENSCSAG00000017920 BRCA2	Compare expression
Simiiformes	10 species Callithrix jacchus (White-tufted-ear marmoset) Cercocebus atys (Sooty mangabey) Macaca fascicularis (Crab-eating macaque) Macaca mulatta (macaque) Macaca nemestrina (Pig-tailed macaque) Papio anubis (Olive baboon) Gorilla gorilla (gorilla) Pan paniscus (bonobo) Pan troglodytes (chimpanzee) Chlorocebus sabaeus (Green monkey)	10 genes ENSCJAG00000018462 BRCA2 ENSCATG00000031672 BRCA2 ENSMFAG00000041961 BRCA2 ENSMMUG00000007197 BRCA2 ENSMNEG00000036002 BRCA2 ENSPANG00000013323 BRCA2 ENSGGOG00000015808 BRCA2 ENSPPAG00000002166 BRCA2 ENSPTRG00000005766 BRCA2 ENSCSAG00000017920 BRCA2	Compare expression
Euarchontoglires	14 species Mus musculus (mouse) Oryctolagus cuniculus (rabbit) Cavia porcellus (guinea pig) Callithrix jacchus (White-tufted-ear marmoset) Cercocebus atys (Sooty mangabey) Macaca fascicularis (Crab-eating macaque) Macaca mulatta (macaque) Macaca nemestrina (Pig-tailed macaque) Papio anubis (Olive baboon) Gorilla gorilla (gorilla) Pan paniscus (bonobo) Pan troglodytes (chimpanzee) Chlorocebus sabaeus (Green monkey) Rattus norvegicus (rat)	14 genes ENSMUSG00000041147 Brca2 ENSOCUG00000016878 BRCA2 ENSCPOG00000005153 BRCA2 ENSCJAG00000018462 BRCA2 ENSCATG00000031672 BRCA2 ENSMFAG00000041961 BRCA2 ENSMMUG00000007197 BRCA2 ENSMNEG00000036002 BRCA2 ENSPANG00000013323 BRCA2 ENSGGOG00000015808 BRCA2 ENSPPAG00000002166 BRCA2 ENSPTRG00000005766 BRCA2 ENSCSAG00000017920 BRCA2 ENSRNOG00000001111 Brca2	Compare expression
Boreoeutheria	22 species Mus musculus (mouse) Canis lupus familiaris (dog) Felis catus (cat) Equus caballus (horse) Sus scrofa (pig) Bos taurus (cattle) Capra hircus (Goat) Ovis aries (Sheep) Oryctolagus cuniculus (rabbit) Cavia porcellus (guinea pig) Callithrix jacchus (White-tufted-ear marmoset) Cercocebus atys (Sooty mangabey) Macaca fascicularis (Crab-eating macaque) Macaca mulatta (macaque) Macaca nemestrina (Pig-tailed macaque) Papio anubis (Olive baboon) Gorilla gorilla (gorilla) Pan paniscus (bonobo) Pan troglodytes (chimpanzee) Chlorocebus sabaeus (Green monkey) Manis javanica (Malayan pangolin) Rattus norvegicus (rat)	22 genes ENSMUSG00000041147 Brca2 ENSCAFG00000006383 BRCA2 ENSFCAG00000025587 BRCA2 ENSECAG00000014890 BRCA2 ENSSSCG00000029039 BRCA2 ENSBTAG00000000988 BRCA2 ENSCHIG00000021344 BRCA2 ENSOARG00000011179 BRCA2 ENSOCUG00000016878 BRCA2 ENSCPOG00000005153 BRCA2 ENSCJAG00000018462 BRCA2 ENSCATG00000031672 BRCA2 ENSMFAG00000041961 BRCA2 ENSMMUG00000007197 BRCA2 ENSMNEG00000036002 BRCA2 ENSPANG00000013323 BRCA2 ENSGGOG00000015808 BRCA2 ENSPPAG00000002166 BRCA2 ENSPTRG00000005766 BRCA2 ENSCSAG00000017920 BRCA2 108406123 BRCA2 ENSRNOG00000001111 Brca2	Compare expression
Theria	23 species Mus musculus (mouse) Canis lupus familiaris (dog) Felis catus (cat) Equus caballus (horse) Sus scrofa (pig) Bos taurus (cattle) Capra hircus (Goat) Ovis aries (Sheep) Oryctolagus cuniculus (rabbit) Cavia porcellus (guinea pig) Callithrix jacchus (White-tufted-ear marmoset) Cercocebus atys (Sooty mangabey) Macaca fascicularis (Crab-eating macaque) Macaca mulatta (macaque) Macaca nemestrina (Pig-tailed macaque) Papio anubis (Olive baboon) Gorilla gorilla (gorilla) Pan paniscus (bonobo) Pan troglodytes (chimpanzee) Chlorocebus sabaeus (Green monkey) Manis javanica (Malayan pangolin) Rattus norvegicus (rat) Monodelphis domestica (opossum)	23 genes ENSMUSG00000041147 Brca2 ENSCAFG00000006383 BRCA2 ENSFCAG00000025587 BRCA2 ENSECAG00000014890 BRCA2 ENSSSCG00000029039 BRCA2 ENSBTAG00000000988 BRCA2 ENSCHIG00000021344 BRCA2 ENSOARG00000011179 BRCA2 ENSOCUG00000016878 BRCA2 ENSCPOG00000005153 BRCA2 ENSCJAG00000018462 BRCA2 ENSCATG00000031672 BRCA2 ENSMFAG00000041961 BRCA2 ENSMMUG00000007197 BRCA2 ENSMNEG00000036002 BRCA2 ENSPANG00000013323 BRCA2 ENSGGOG00000015808 BRCA2 ENSPPAG00000002166 BRCA2 ENSPTRG00000005766 BRCA2 ENSCSAG00000017920 BRCA2 108406123 BRCA2 ENSRNOG00000001111 Brca2 ENSMODG00000009516	Compare expression
Mammalia	24 species Mus musculus (mouse) Canis lupus familiaris (dog) Felis catus (cat) Equus caballus (horse) Sus scrofa (pig) Bos taurus (cattle) Capra hircus (Goat) Ovis aries (Sheep) Oryctolagus cuniculus (rabbit) Cavia porcellus (guinea pig) Ornithorhynchus anatinus (platypus) Callithrix jacchus (White-tufted-ear marmoset) Cercocebus atys (Sooty mangabey) Macaca fascicularis (Crab-eating macaque) Macaca mulatta (macaque) Macaca nemestrina (Pig-tailed macaque) Papio anubis (Olive baboon) Gorilla gorilla (gorilla) Pan paniscus (bonobo) Pan troglodytes (chimpanzee) Chlorocebus sabaeus (Green monkey) Manis javanica (Malayan pangolin) Rattus norvegicus (rat) Monodelphis domestica (opossum)	24 genes ENSMUSG00000041147 Brca2 ENSCAFG00000006383 BRCA2 ENSFCAG00000025587 BRCA2 ENSECAG00000014890 BRCA2 ENSSSCG00000029039 BRCA2 ENSBTAG00000000988 BRCA2 ENSCHIG00000021344 BRCA2 ENSOARG00000011179 BRCA2 ENSOCUG00000016878 BRCA2 ENSCPOG00000005153 BRCA2 ENSOANG00000015481 BRCA2 ENSCJAG00000018462 BRCA2 ENSCATG00000031672 BRCA2 ENSMFAG00000041961 BRCA2 ENSMMUG00000007197 BRCA2 ENSMNEG00000036002 BRCA2 ENSPANG00000013323 BRCA2 ENSGGOG00000015808 BRCA2 ENSPPAG00000002166 BRCA2 ENSPTRG00000005766 BRCA2 ENSCSAG00000017920 BRCA2 108406123 BRCA2 ENSRNOG00000001111 Brca2 ENSMODG00000009516	Compare expression
Amniota	26 species Mus musculus (mouse) Canis lupus familiaris (dog) Felis catus (cat) Equus caballus (horse) Sus scrofa (pig) Bos taurus (cattle) Capra hircus (Goat) Ovis aries (Sheep) Oryctolagus cuniculus (rabbit) Cavia porcellus (guinea pig) Gallus gallus (chicken) Meleagris gallopavo (Wild turkey) Ornithorhynchus anatinus (platypus) Callithrix jacchus (White-tufted-ear marmoset) Cercocebus atys (Sooty mangabey) Macaca fascicularis (Crab-eating macaque) Macaca mulatta (macaque) Macaca nemestrina (Pig-tailed macaque) Papio anubis (Olive baboon) Gorilla gorilla (gorilla) Pan paniscus (bonobo) Pan troglodytes (chimpanzee) Chlorocebus sabaeus (Green monkey) Manis javanica (Malayan pangolin) Rattus norvegicus (rat) Monodelphis domestica (opossum)	26 genes ENSMUSG00000041147 Brca2 ENSCAFG00000006383 BRCA2 ENSFCAG00000025587 BRCA2 ENSECAG00000014890 BRCA2 ENSSSCG00000029039 BRCA2 ENSBTAG00000000988 BRCA2 ENSCHIG00000021344 BRCA2 ENSOARG00000011179 BRCA2 ENSOCUG00000016878 BRCA2 ENSCPOG00000005153 BRCA2 ENSGALG00000017073 BRCA2 ENSMGAG00000015077 BRCA2 ENSOANG00000015481 BRCA2 ENSCJAG00000018462 BRCA2 ENSCATG00000031672 BRCA2 ENSMFAG00000041961 BRCA2 ENSMMUG00000007197 BRCA2 ENSMNEG00000036002 BRCA2 ENSPANG00000013323 BRCA2 ENSGGOG00000015808 BRCA2 ENSPPAG00000002166 BRCA2 ENSPTRG00000005766 BRCA2 ENSCSAG00000017920 BRCA2 108406123 BRCA2 ENSRNOG00000001111 Brca2 ENSMODG00000009516	Compare expression

Showing 1 to 8 of 8 entries

Orthology information comes from OMA : ENSG00000139618.

Cross-references

CCDS

CCDS9344 (CCDS9344.1)

Ensembl

ENSG00000139618 (BRCA2)

HGNC

HGNC:1101 (BRCA2)

EMBL

AF489725,AF489726,AF489727,AF489728,AF489729,AF489730,AF489731,AF489732

GeneCards

ENSG00000139618

UniProtKB/Swiss-Prot

BRCA2_HUMAN,P51587

UniProtKB/TrEMBL

A0A590UJ24,A0A590UJ24_HUMAN,A0A590UJI7,A0A590UJI7_HUMAN,A0A590UJU6,A0A590UJU6_HUMAN,A0A7P0T9D7,A0A7P0T9D7_HUMAN