Search Genes

Gene : CYP46A1 - ENSFCAG00000001352 - Felis catus (cat)

General information

Expressed in prefrontal cortex and 7 other cell types or tissues.

Gene identifier

ENSFCAG00000001352

Name

CYP46A1

Description

cholesterol 24-hydroxylase [Source:NCBI gene (formerly Entrezgene);Acc:101093112]

Organism

Felis catus (cat)

Synonym(s)

Orthologs

62 orthologs

Paralogs

38 paralogs

Source data

Retrieve all processed expression values for that gene

Expression graph

80%

Expression table

80%

Reported absence of expression

80%

Orthologs

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Taxon Name	Species with orthologs	Gene(s)	Expression comparison
Carnivora	1 species Canis lupus familiaris (dog)	1 gene ENSCAFG00000017838 CYP46A1	Compare expression
Laurasiatheria	7 species Canis lupus familiaris (dog) Equus caballus (horse) Sus scrofa (pig) Bos taurus (cattle) Capra hircus (Goat) Ovis aries (Sheep) Manis javanica (Malayan pangolin)	7 genes ENSCAFG00000017838 CYP46A1 ENSECAG00000007407 CYP46A1 ENSSSCG00000002510 CYP46A1 ENSBTAG00000035544 CYP46A1 ENSCHIG00000026315 CYP46A1 ENSOARG00000000933 CYP46A1 108394816 LOC108394816	Compare expression
Boreoeutheria	23 species Homo sapiens (human) Mus musculus (mouse) Canis lupus familiaris (dog) Equus caballus (horse) Sus scrofa (pig) Bos taurus (cattle) Capra hircus (Goat) Ovis aries (Sheep) Oryctolagus cuniculus (rabbit) Cavia porcellus (guinea pig) Callithrix jacchus (White-tufted-ear marmoset) Cercocebus atys (Sooty mangabey) Macaca fascicularis (Crab-eating macaque) Macaca mulatta (macaque) Macaca nemestrina (Pig-tailed macaque) Papio anubis (Olive baboon) Gorilla gorilla (gorilla) Pan paniscus (bonobo) Pan troglodytes (chimpanzee) Microcebus murinus (Gray mouse lemur) Chlorocebus sabaeus (Green monkey) Manis javanica (Malayan pangolin) Rattus norvegicus (rat)	23 genes ENSG00000036530 CYP46A1 ENSMUSG00000021259 Cyp46a1 ENSCAFG00000017838 CYP46A1 ENSECAG00000007407 CYP46A1 ENSSSCG00000002510 CYP46A1 ENSBTAG00000035544 CYP46A1 ENSCHIG00000026315 CYP46A1 ENSOARG00000000933 CYP46A1 ENSOCUG00000027965 CYP46A1 ENSCPOG00000025436 CYP46A1 ENSCJAG00000006798 CYP46A1 ENSCATG00000011974 CYP46A1 ENSMFAG00000002756 CYP46A1 ENSMMUG00000000100 CYP46A1 ENSMNEG00000006524 CYP46A1 ENSPANG00000015187 CYP46A1 ENSGGOG00000004816 CYP46A1 ENSPPAG00000036038 CYP46A1 ENSPTRG00000006713 CYP46A1 ENSMICG00000015128 CYP46A1 ENSCSAG00000010408 CYP46A1 108394816 LOC108394816 ENSRNOG00000007147 Cyp46a1	Compare expression
Mammalia	24 species Homo sapiens (human) Mus musculus (mouse) Canis lupus familiaris (dog) Equus caballus (horse) Sus scrofa (pig) Bos taurus (cattle) Capra hircus (Goat) Ovis aries (Sheep) Oryctolagus cuniculus (rabbit) Cavia porcellus (guinea pig) Ornithorhynchus anatinus (platypus) Callithrix jacchus (White-tufted-ear marmoset) Cercocebus atys (Sooty mangabey) Macaca fascicularis (Crab-eating macaque) Macaca mulatta (macaque) Macaca nemestrina (Pig-tailed macaque) Papio anubis (Olive baboon) Gorilla gorilla (gorilla) Pan paniscus (bonobo) Pan troglodytes (chimpanzee) Microcebus murinus (Gray mouse lemur) Chlorocebus sabaeus (Green monkey) Manis javanica (Malayan pangolin) Rattus norvegicus (rat)	24 genes ENSG00000036530 CYP46A1 ENSMUSG00000021259 Cyp46a1 ENSCAFG00000017838 CYP46A1 ENSECAG00000007407 CYP46A1 ENSSSCG00000002510 CYP46A1 ENSBTAG00000035544 CYP46A1 ENSCHIG00000026315 CYP46A1 ENSOARG00000000933 CYP46A1 ENSOCUG00000027965 CYP46A1 ENSCPOG00000025436 CYP46A1 ENSOANG00000007692 CYP46A1 ENSCJAG00000006798 CYP46A1 ENSCATG00000011974 CYP46A1 ENSMFAG00000002756 CYP46A1 ENSMMUG00000000100 CYP46A1 ENSMNEG00000006524 CYP46A1 ENSPANG00000015187 CYP46A1 ENSGGOG00000004816 CYP46A1 ENSPPAG00000036038 CYP46A1 ENSPTRG00000006713 CYP46A1 ENSMICG00000015128 CYP46A1 ENSCSAG00000010408 CYP46A1 108394816 LOC108394816 ENSRNOG00000007147 Cyp46a1	Compare expression
Amniota	27 species Homo sapiens (human) Mus musculus (mouse) Canis lupus familiaris (dog) Equus caballus (horse) Sus scrofa (pig) Bos taurus (cattle) Capra hircus (Goat) Ovis aries (Sheep) Oryctolagus cuniculus (rabbit) Cavia porcellus (guinea pig) Gallus gallus (chicken) Meleagris gallopavo (Wild turkey) Ornithorhynchus anatinus (platypus) Callithrix jacchus (White-tufted-ear marmoset) Cercocebus atys (Sooty mangabey) Macaca fascicularis (Crab-eating macaque) Macaca mulatta (macaque) Macaca nemestrina (Pig-tailed macaque) Papio anubis (Olive baboon) Gorilla gorilla (gorilla) Pan paniscus (bonobo) Pan troglodytes (chimpanzee) Microcebus murinus (Gray mouse lemur) Chlorocebus sabaeus (Green monkey) Manis javanica (Malayan pangolin) Rattus norvegicus (rat) Anolis carolinensis (green anole)	28 genes ENSG00000036530 CYP46A1 ENSMUSG00000021259 Cyp46a1 ENSCAFG00000017838 CYP46A1 ENSECAG00000007407 CYP46A1 ENSSSCG00000002510 CYP46A1 ENSBTAG00000035544 CYP46A1 ENSCHIG00000026315 CYP46A1 ENSOARG00000000933 CYP46A1 ENSOCUG00000027965 CYP46A1 ENSCPOG00000025436 CYP46A1 ENSGALG00000011162 CYP46A1 ENSMGAG00000013268 CYP46A1 ENSOANG00000007692 CYP46A1 ENSCJAG00000006798 CYP46A1 ENSCATG00000011974 CYP46A1 ENSMFAG00000002756 CYP46A1 ENSMMUG00000000100 CYP46A1 ENSMNEG00000006524 CYP46A1 ENSPANG00000015187 CYP46A1 ENSGGOG00000004816 CYP46A1 ENSPPAG00000036038 CYP46A1 ENSPTRG00000006713 CYP46A1 ENSMICG00000015128 CYP46A1 ENSCSAG00000010408 CYP46A1 108394816 LOC108394816 ENSRNOG00000007147 Cyp46a1 ENSACAG00000013099 LOC100552607 ENSACAG00000013156	Compare expression
Tetrapoda	28 species Homo sapiens (human) Mus musculus (mouse) Canis lupus familiaris (dog) Equus caballus (horse) Sus scrofa (pig) Bos taurus (cattle) Capra hircus (Goat) Ovis aries (Sheep) Oryctolagus cuniculus (rabbit) Cavia porcellus (guinea pig) Gallus gallus (chicken) Meleagris gallopavo (Wild turkey) Ornithorhynchus anatinus (platypus) Callithrix jacchus (White-tufted-ear marmoset) Cercocebus atys (Sooty mangabey) Macaca fascicularis (Crab-eating macaque) Macaca mulatta (macaque) Macaca nemestrina (Pig-tailed macaque) Papio anubis (Olive baboon) Gorilla gorilla (gorilla) Pan paniscus (bonobo) Pan troglodytes (chimpanzee) Microcebus murinus (Gray mouse lemur) Chlorocebus sabaeus (Green monkey) Manis javanica (Malayan pangolin) Rattus norvegicus (rat) Xenopus tropicalis (western clawed frog) Anolis carolinensis (green anole)	29 genes ENSG00000036530 CYP46A1 ENSMUSG00000021259 Cyp46a1 ENSCAFG00000017838 CYP46A1 ENSECAG00000007407 CYP46A1 ENSSSCG00000002510 CYP46A1 ENSBTAG00000035544 CYP46A1 ENSCHIG00000026315 CYP46A1 ENSOARG00000000933 CYP46A1 ENSOCUG00000027965 CYP46A1 ENSCPOG00000025436 CYP46A1 ENSGALG00000011162 CYP46A1 ENSMGAG00000013268 CYP46A1 ENSOANG00000007692 CYP46A1 ENSCJAG00000006798 CYP46A1 ENSCATG00000011974 CYP46A1 ENSMFAG00000002756 CYP46A1 ENSMMUG00000000100 CYP46A1 ENSMNEG00000006524 CYP46A1 ENSPANG00000015187 CYP46A1 ENSGGOG00000004816 CYP46A1 ENSPPAG00000036038 CYP46A1 ENSPTRG00000006713 CYP46A1 ENSMICG00000015128 CYP46A1 ENSCSAG00000010408 CYP46A1 108394816 LOC108394816 ENSRNOG00000007147 Cyp46a1 ENSXETG00000011440 cyp46a1.3 ENSACAG00000013099 LOC100552607 ENSACAG00000013156	Compare expression
Euteleostomi	42 species Homo sapiens (human) Mus musculus (mouse) Danio rerio (zebrafish) Canis lupus familiaris (dog) Equus caballus (horse) Sus scrofa (pig) Bos taurus (cattle) Capra hircus (Goat) Ovis aries (Sheep) Oryctolagus cuniculus (rabbit) Cavia porcellus (guinea pig) Gallus gallus (chicken) Meleagris gallopavo (Wild turkey) Ornithorhynchus anatinus (platypus) Callithrix jacchus (White-tufted-ear marmoset) Cercocebus atys (Sooty mangabey) Macaca fascicularis (Crab-eating macaque) Macaca mulatta (macaque) Macaca nemestrina (Pig-tailed macaque) Papio anubis (Olive baboon) Gorilla gorilla (gorilla) Pan paniscus (bonobo) Pan troglodytes (chimpanzee) Microcebus murinus (Gray mouse lemur) Chlorocebus sabaeus (Green monkey) Manis javanica (Malayan pangolin) Rattus norvegicus (rat) Xenopus tropicalis (western clawed frog) Anolis carolinensis (green anole) Lepisosteus oculatus (Spotted gar) Anguilla anguilla (European freshwater eel) Astyanax mexicanus (Blind cave fish) Esox lucius (Northern pike) Salmo salar (Atlantic salmon) Gadus morhua (Atlantic cod) Poecilia reticulata (Guppy) Oryzias latipes (Japanese rice fish) Astatotilapia calliptera (Eastern happy) Neolamprologus brichardi (Fairy cichlid) Scophthalmus maximus (Turbot) Gasterosteus aculeatus (Three-spined stickleback) Nothobranchius furzeri (Turquoise killifish)	61 genes ENSG00000036530 CYP46A1 ENSMUSG00000021259 Cyp46a1 ENSDARG00000004262 cyp46a1.2 ENSDARG00000012137 cyp46a1.1 ENSDARG00000089177 cyp46a1.3 ENSDARG00000093477 zgc:123299 ENSDARG00000113820 cyp46a1.4 ENSCAFG00000017838 CYP46A1 ENSECAG00000007407 CYP46A1 ENSSSCG00000002510 CYP46A1 ENSBTAG00000035544 CYP46A1 ENSCHIG00000026315 CYP46A1 ENSOARG00000000933 CYP46A1 ENSOCUG00000027965 CYP46A1 ENSCPOG00000025436 CYP46A1 ENSGALG00000011162 CYP46A1 ENSMGAG00000013268 CYP46A1 ENSOANG00000007692 CYP46A1 ENSCJAG00000006798 CYP46A1 ENSCATG00000011974 CYP46A1 ENSMFAG00000002756 CYP46A1 ENSMMUG00000000100 CYP46A1 ENSMNEG00000006524 CYP46A1 ENSPANG00000015187 CYP46A1 ENSGGOG00000004816 CYP46A1 ENSPPAG00000036038 CYP46A1 ENSPTRG00000006713 CYP46A1 ENSMICG00000015128 CYP46A1 ENSCSAG00000010408 CYP46A1 108394816 LOC108394816 ENSRNOG00000007147 Cyp46a1 ENSXETG00000011440 cyp46a1.3 ENSACAG00000013099 LOC100552607 ENSACAG00000013156 ENSLOCG00000008757 cyp46a1.4 118230143 LOC118230143 118230144 LOC118230144 118230145 LOC118230145 118230146 LOC118230146 118230147 LOC118230147 ENSAMXG00000009160 cyp46a1.3 ENSELUG00000018130 cyp46a1.4 ENSSSAG00000039498 LOC106571110 ENSSSAG00000040165 ENSSSAG00000040391 LOC106571109 ENSSSAG00000045521 LOC106608238 ENSGMOG00000019372 ENSPREG00000017599 ENSPREG00000018183 ENSORLG00000010516 LOC101165021 ENSORLG00000010534 LOC101165274 ENSACLG00000024835 ENSACLG00000024870 ENSACLG00000024900 ENSACLG00000024908 ENSACLG00000024918 ENSNBRG00000018823 CYP46A1 ENSNBRG00000018940 ENSSMAG00000003961 cyp46a1.4 ENSGACG00000005410 cyp46a1.4 ENSNFUG00015003221 CYP46A1	Compare expression
Chordata	43 species Homo sapiens (human) Mus musculus (mouse) Danio rerio (zebrafish) Canis lupus familiaris (dog) Equus caballus (horse) Sus scrofa (pig) Bos taurus (cattle) Capra hircus (Goat) Ovis aries (Sheep) Oryctolagus cuniculus (rabbit) Cavia porcellus (guinea pig) Gallus gallus (chicken) Meleagris gallopavo (Wild turkey) Ornithorhynchus anatinus (platypus) Callithrix jacchus (White-tufted-ear marmoset) Cercocebus atys (Sooty mangabey) Macaca fascicularis (Crab-eating macaque) Macaca mulatta (macaque) Macaca nemestrina (Pig-tailed macaque) Papio anubis (Olive baboon) Gorilla gorilla (gorilla) Pan paniscus (bonobo) Pan troglodytes (chimpanzee) Microcebus murinus (Gray mouse lemur) Chlorocebus sabaeus (Green monkey) Manis javanica (Malayan pangolin) Rattus norvegicus (rat) Xenopus tropicalis (western clawed frog) Anolis carolinensis (green anole) Lepisosteus oculatus (Spotted gar) Anguilla anguilla (European freshwater eel) Astyanax mexicanus (Blind cave fish) Esox lucius (Northern pike) Salmo salar (Atlantic salmon) Gadus morhua (Atlantic cod) Poecilia reticulata (Guppy) Oryzias latipes (Japanese rice fish) Astatotilapia calliptera (Eastern happy) Neolamprologus brichardi (Fairy cichlid) Scophthalmus maximus (Turbot) Gasterosteus aculeatus (Three-spined stickleback) Nothobranchius furzeri (Turquoise killifish) Branchiostoma lanceolatum (Common lancelet)	62 genes ENSG00000036530 CYP46A1 ENSMUSG00000021259 Cyp46a1 ENSDARG00000004262 cyp46a1.2 ENSDARG00000012137 cyp46a1.1 ENSDARG00000089177 cyp46a1.3 ENSDARG00000093477 zgc:123299 ENSDARG00000113820 cyp46a1.4 ENSCAFG00000017838 CYP46A1 ENSECAG00000007407 CYP46A1 ENSSSCG00000002510 CYP46A1 ENSBTAG00000035544 CYP46A1 ENSCHIG00000026315 CYP46A1 ENSOARG00000000933 CYP46A1 ENSOCUG00000027965 CYP46A1 ENSCPOG00000025436 CYP46A1 ENSGALG00000011162 CYP46A1 ENSMGAG00000013268 CYP46A1 ENSOANG00000007692 CYP46A1 ENSCJAG00000006798 CYP46A1 ENSCATG00000011974 CYP46A1 ENSMFAG00000002756 CYP46A1 ENSMMUG00000000100 CYP46A1 ENSMNEG00000006524 CYP46A1 ENSPANG00000015187 CYP46A1 ENSGGOG00000004816 CYP46A1 ENSPPAG00000036038 CYP46A1 ENSPTRG00000006713 CYP46A1 ENSMICG00000015128 CYP46A1 ENSCSAG00000010408 CYP46A1 108394816 LOC108394816 ENSRNOG00000007147 Cyp46a1 ENSXETG00000011440 cyp46a1.3 ENSACAG00000013099 LOC100552607 ENSACAG00000013156 ENSLOCG00000008757 cyp46a1.4 118230143 LOC118230143 118230144 LOC118230144 118230145 LOC118230145 118230146 LOC118230146 118230147 LOC118230147 ENSAMXG00000009160 cyp46a1.3 ENSELUG00000018130 cyp46a1.4 ENSSSAG00000039498 LOC106571110 ENSSSAG00000040165 ENSSSAG00000040391 LOC106571109 ENSSSAG00000045521 LOC106608238 ENSGMOG00000019372 ENSPREG00000017599 ENSPREG00000018183 ENSORLG00000010516 LOC101165021 ENSORLG00000010534 LOC101165274 ENSACLG00000024835 ENSACLG00000024870 ENSACLG00000024900 ENSACLG00000024908 ENSACLG00000024918 ENSNBRG00000018823 CYP46A1 ENSNBRG00000018940 ENSSMAG00000003961 cyp46a1.4 ENSGACG00000005410 cyp46a1.4 ENSNFUG00015003221 CYP46A1 BL22740 CYP46A1	Compare expression

Showing 1 to 8 of 8 entries

Orthology information comes from OMA : ENSFCAG00000001352.

Paralogs (same species)

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Taxon Name	Gene(s)	Expression comparison	See details
Metazoa	38 genes ENSFCAG00000000344 CYP1A2 ENSFCAG00000001254 CYP17A1 ENSFCAG00000001547 CYP4V2 ENSFCAG00000002452 CYP24A1 ENSFCAG00000002762 CYP4B1 ENSFCAG00000004522 CYP21A2 ENSFCAG00000007063 CYP27A1 ENSFCAG00000007168 CYP4X1 ENSFCAG00000008003 CYP7A1 ENSFCAG00000008557 CYP2A13 ENSFCAG00000008623 CYP4F8 ENSFCAG00000010211 CYP7B1 ENSFCAG00000010566 TBXAS1 ENSFCAG00000010871 CYP11A1 ENSFCAG00000011052 CYP39A1 ENSFCAG00000011145 CYP2J2 ENSFCAG00000011383 CYP2R1 ENSFCAG00000013094 CYP2S1 ENSFCAG00000013628 CYP27C1 ENSFCAG00000013762 CYP2E2 ENSFCAG00000014701 CYP27B1 ENSFCAG00000015335 CYP2U1 ENSFCAG00000019378 CYP2G2 ENSFCAG00000025479 CYP51A1 ENSFCAG00000026110 CYP2D6 ENSFCAG00000027930 CYP2F1 ENSFCAG00000028217 CYP2C41 ENSFCAG00000028583 CYP8B1 ENSFCAG00000028754 CYP4F22 ENSFCAG00000030511 PTGIS ENSFCAG00000031987 LOC101089804 ENSFCAG00000033530 CYP2B6 ENSFCAG00000040403 CYP2A25 ENSFCAG00000040455 CYP3A132 ENSFCAG00000042155 LOC105260134 ENSFCAG00000043102 CYP1B1 ENSFCAG00000046713 CYP3A131 ENSFCAG00000053792 LOC101087695	Compare expression: table \| graph

Showing 1 to 1 of 1 entries

Paralogy information comes from OMA : ENSFCAG00000001352.

Cross-references

Ensembl

ENSFCAG00000001352 (CYP46A1)

HGNC

HGNC:2641 (CYP46A1)

EMBL

AANG04004659

UniProtKB/TrEMBL

A0A5F5Y6B7,A0A5F5Y6B7_FELCA,M3VWH5,M3VWH5_FELCA