Search Genes

Gene : COMT - ENSG00000093010 - Homo sapiens (human)

General information

Expressed in right adrenal gland cortex and 207 other cell types or tissues.

Gene identifier

ENSG00000093010

Name

COMT

Description

catechol-O-methyltransferase [Source:HGNC Symbol;Acc:HGNC:2228]

Organism

Homo sapiens (human)

Synonym(s)

Orthologs

55 orthologs

Paralogs

2 paralogs

Source data

Retrieve all processed expression values for that gene

Expression graph

80%

Expression table

80%

Reported absence of expression

80%

Orthologs

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Taxon Name	Species with orthologs	Gene(s)	Expression comparison
Homininae	3 species Gorilla gorilla (gorilla) Pan paniscus (bonobo) Pan troglodytes (chimpanzee)	3 genes ENSGGOG00000006699 COMT ENSPPAG00000027543 ENSPTRG00000014070 COMT	Compare expression
Catarrhini	9 species Cercocebus atys (Sooty mangabey) Macaca fascicularis (Crab-eating macaque) Macaca mulatta (macaque) Macaca nemestrina (Pig-tailed macaque) Papio anubis (Olive baboon) Gorilla gorilla (gorilla) Pan paniscus (bonobo) Pan troglodytes (chimpanzee) Chlorocebus sabaeus (Green monkey)	9 genes ENSCATG00000026178 COMT ENSMFAG00000030334 COMT ENSMMUG00000054068 COMT ENSMNEG00000022654 COMT ENSPANG00000006826 COMT ENSGGOG00000006699 COMT ENSPPAG00000027543 ENSPTRG00000014070 COMT ENSCSAG00000011940 COMT	Compare expression
Simiiformes	10 species Callithrix jacchus (White-tufted-ear marmoset) Cercocebus atys (Sooty mangabey) Macaca fascicularis (Crab-eating macaque) Macaca mulatta (macaque) Macaca nemestrina (Pig-tailed macaque) Papio anubis (Olive baboon) Gorilla gorilla (gorilla) Pan paniscus (bonobo) Pan troglodytes (chimpanzee) Chlorocebus sabaeus (Green monkey)	10 genes ENSCJAG00000014538 COMT ENSCATG00000026178 COMT ENSMFAG00000030334 COMT ENSMMUG00000054068 COMT ENSMNEG00000022654 COMT ENSPANG00000006826 COMT ENSGGOG00000006699 COMT ENSPPAG00000027543 ENSPTRG00000014070 COMT ENSCSAG00000011940 COMT	Compare expression
Primates	11 species Callithrix jacchus (White-tufted-ear marmoset) Cercocebus atys (Sooty mangabey) Macaca fascicularis (Crab-eating macaque) Macaca mulatta (macaque) Macaca nemestrina (Pig-tailed macaque) Papio anubis (Olive baboon) Gorilla gorilla (gorilla) Pan paniscus (bonobo) Pan troglodytes (chimpanzee) Microcebus murinus (Gray mouse lemur) Chlorocebus sabaeus (Green monkey)	11 genes ENSCJAG00000014538 COMT ENSCATG00000026178 COMT ENSMFAG00000030334 COMT ENSMMUG00000054068 COMT ENSMNEG00000022654 COMT ENSPANG00000006826 COMT ENSGGOG00000006699 COMT ENSPPAG00000027543 ENSPTRG00000014070 COMT ENSMICG00000015309 COMT ENSCSAG00000011940 COMT	Compare expression
Euarchontoglires	15 species Mus musculus (mouse) Oryctolagus cuniculus (rabbit) Cavia porcellus (guinea pig) Callithrix jacchus (White-tufted-ear marmoset) Cercocebus atys (Sooty mangabey) Macaca fascicularis (Crab-eating macaque) Macaca mulatta (macaque) Macaca nemestrina (Pig-tailed macaque) Papio anubis (Olive baboon) Gorilla gorilla (gorilla) Pan paniscus (bonobo) Pan troglodytes (chimpanzee) Microcebus murinus (Gray mouse lemur) Chlorocebus sabaeus (Green monkey) Rattus norvegicus (rat)	15 genes ENSMUSG00000000326 Comt ENSOCUG00000006297 COMT ENSCPOG00000004445 COMT ENSCJAG00000014538 COMT ENSCATG00000026178 COMT ENSMFAG00000030334 COMT ENSMMUG00000054068 COMT ENSMNEG00000022654 COMT ENSPANG00000006826 COMT ENSGGOG00000006699 COMT ENSPPAG00000027543 ENSPTRG00000014070 COMT ENSMICG00000015309 COMT ENSCSAG00000011940 COMT ENSRNOG00000001889 Comt	Compare expression
Boreoeutheria	22 species Mus musculus (mouse) Canis lupus familiaris (dog) Felis catus (cat) Equus caballus (horse) Sus scrofa (pig) Bos taurus (cattle) Capra hircus (Goat) Oryctolagus cuniculus (rabbit) Cavia porcellus (guinea pig) Callithrix jacchus (White-tufted-ear marmoset) Cercocebus atys (Sooty mangabey) Macaca fascicularis (Crab-eating macaque) Macaca mulatta (macaque) Macaca nemestrina (Pig-tailed macaque) Papio anubis (Olive baboon) Gorilla gorilla (gorilla) Pan paniscus (bonobo) Pan troglodytes (chimpanzee) Microcebus murinus (Gray mouse lemur) Chlorocebus sabaeus (Green monkey) Manis javanica (Malayan pangolin) Rattus norvegicus (rat)	22 genes ENSMUSG00000000326 Comt ENSCAFG00000014253 COMT ENSFCAG00000002684 COMT ENSECAG00000005359 COMT ENSSSCG00000010132 COMT ENSBTAG00000019516 COMT ENSCHIG00000006984 COMT ENSOCUG00000006297 COMT ENSCPOG00000004445 COMT ENSCJAG00000014538 COMT ENSCATG00000026178 COMT ENSMFAG00000030334 COMT ENSMMUG00000054068 COMT ENSMNEG00000022654 COMT ENSPANG00000006826 COMT ENSGGOG00000006699 COMT ENSPPAG00000027543 ENSPTRG00000014070 COMT ENSMICG00000015309 COMT ENSCSAG00000011940 COMT 108406868 COMT ENSRNOG00000001889 Comt	Compare expression
Theria	23 species Mus musculus (mouse) Canis lupus familiaris (dog) Felis catus (cat) Equus caballus (horse) Sus scrofa (pig) Bos taurus (cattle) Capra hircus (Goat) Oryctolagus cuniculus (rabbit) Cavia porcellus (guinea pig) Callithrix jacchus (White-tufted-ear marmoset) Cercocebus atys (Sooty mangabey) Macaca fascicularis (Crab-eating macaque) Macaca mulatta (macaque) Macaca nemestrina (Pig-tailed macaque) Papio anubis (Olive baboon) Gorilla gorilla (gorilla) Pan paniscus (bonobo) Pan troglodytes (chimpanzee) Microcebus murinus (Gray mouse lemur) Chlorocebus sabaeus (Green monkey) Manis javanica (Malayan pangolin) Rattus norvegicus (rat) Monodelphis domestica (opossum)	23 genes ENSMUSG00000000326 Comt ENSCAFG00000014253 COMT ENSFCAG00000002684 COMT ENSECAG00000005359 COMT ENSSSCG00000010132 COMT ENSBTAG00000019516 COMT ENSCHIG00000006984 COMT ENSOCUG00000006297 COMT ENSCPOG00000004445 COMT ENSCJAG00000014538 COMT ENSCATG00000026178 COMT ENSMFAG00000030334 COMT ENSMMUG00000054068 COMT ENSMNEG00000022654 COMT ENSPANG00000006826 COMT ENSGGOG00000006699 COMT ENSPPAG00000027543 ENSPTRG00000014070 COMT ENSMICG00000015309 COMT ENSCSAG00000011940 COMT 108406868 COMT ENSRNOG00000001889 Comt ENSMODG00000019644 COMT	Compare expression
Mammalia	24 species Mus musculus (mouse) Canis lupus familiaris (dog) Felis catus (cat) Equus caballus (horse) Sus scrofa (pig) Bos taurus (cattle) Capra hircus (Goat) Oryctolagus cuniculus (rabbit) Cavia porcellus (guinea pig) Ornithorhynchus anatinus (platypus) Callithrix jacchus (White-tufted-ear marmoset) Cercocebus atys (Sooty mangabey) Macaca fascicularis (Crab-eating macaque) Macaca mulatta (macaque) Macaca nemestrina (Pig-tailed macaque) Papio anubis (Olive baboon) Gorilla gorilla (gorilla) Pan paniscus (bonobo) Pan troglodytes (chimpanzee) Microcebus murinus (Gray mouse lemur) Chlorocebus sabaeus (Green monkey) Manis javanica (Malayan pangolin) Rattus norvegicus (rat) Monodelphis domestica (opossum)	24 genes ENSMUSG00000000326 Comt ENSCAFG00000014253 COMT ENSFCAG00000002684 COMT ENSECAG00000005359 COMT ENSSSCG00000010132 COMT ENSBTAG00000019516 COMT ENSCHIG00000006984 COMT ENSOCUG00000006297 COMT ENSCPOG00000004445 COMT ENSOANG00000041289 COMT ENSCJAG00000014538 COMT ENSCATG00000026178 COMT ENSMFAG00000030334 COMT ENSMMUG00000054068 COMT ENSMNEG00000022654 COMT ENSPANG00000006826 COMT ENSGGOG00000006699 COMT ENSPPAG00000027543 ENSPTRG00000014070 COMT ENSMICG00000015309 COMT ENSCSAG00000011940 COMT 108406868 COMT ENSRNOG00000001889 Comt ENSMODG00000019644 COMT	Compare expression
Amniota	26 species Mus musculus (mouse) Canis lupus familiaris (dog) Felis catus (cat) Equus caballus (horse) Sus scrofa (pig) Bos taurus (cattle) Capra hircus (Goat) Oryctolagus cuniculus (rabbit) Cavia porcellus (guinea pig) Gallus gallus (chicken) Meleagris gallopavo (Wild turkey) Ornithorhynchus anatinus (platypus) Callithrix jacchus (White-tufted-ear marmoset) Cercocebus atys (Sooty mangabey) Macaca fascicularis (Crab-eating macaque) Macaca mulatta (macaque) Macaca nemestrina (Pig-tailed macaque) Papio anubis (Olive baboon) Gorilla gorilla (gorilla) Pan paniscus (bonobo) Pan troglodytes (chimpanzee) Microcebus murinus (Gray mouse lemur) Chlorocebus sabaeus (Green monkey) Manis javanica (Malayan pangolin) Rattus norvegicus (rat) Monodelphis domestica (opossum)	26 genes ENSMUSG00000000326 Comt ENSCAFG00000014253 COMT ENSFCAG00000002684 COMT ENSECAG00000005359 COMT ENSSSCG00000010132 COMT ENSBTAG00000019516 COMT ENSCHIG00000006984 COMT ENSOCUG00000006297 COMT ENSCPOG00000004445 COMT ENSGALG00000002024 COMT ENSMGAG00000001429 COMT ENSOANG00000041289 COMT ENSCJAG00000014538 COMT ENSCATG00000026178 COMT ENSMFAG00000030334 COMT ENSMMUG00000054068 COMT ENSMNEG00000022654 COMT ENSPANG00000006826 COMT ENSGGOG00000006699 COMT ENSPPAG00000027543 ENSPTRG00000014070 COMT ENSMICG00000015309 COMT ENSCSAG00000011940 COMT 108406868 COMT ENSRNOG00000001889 Comt ENSMODG00000019644 COMT	Compare expression
Tetrapoda	28 species Mus musculus (mouse) Canis lupus familiaris (dog) Felis catus (cat) Equus caballus (horse) Sus scrofa (pig) Bos taurus (cattle) Capra hircus (Goat) Oryctolagus cuniculus (rabbit) Cavia porcellus (guinea pig) Gallus gallus (chicken) Meleagris gallopavo (Wild turkey) Ornithorhynchus anatinus (platypus) Callithrix jacchus (White-tufted-ear marmoset) Cercocebus atys (Sooty mangabey) Macaca fascicularis (Crab-eating macaque) Macaca mulatta (macaque) Macaca nemestrina (Pig-tailed macaque) Papio anubis (Olive baboon) Gorilla gorilla (gorilla) Pan paniscus (bonobo) Pan troglodytes (chimpanzee) Microcebus murinus (Gray mouse lemur) Chlorocebus sabaeus (Green monkey) Manis javanica (Malayan pangolin) Rattus norvegicus (rat) Monodelphis domestica (opossum) Xenopus laevis (African clawed frog) Xenopus tropicalis (western clawed frog)	32 genes ENSMUSG00000000326 Comt ENSCAFG00000014253 COMT ENSFCAG00000002684 COMT ENSECAG00000005359 COMT ENSSSCG00000010132 COMT ENSBTAG00000019516 COMT ENSCHIG00000006984 COMT ENSOCUG00000006297 COMT ENSCPOG00000004445 COMT ENSGALG00000002024 COMT ENSMGAG00000001429 COMT ENSOANG00000041289 COMT ENSCJAG00000014538 COMT ENSCATG00000026178 COMT ENSMFAG00000030334 COMT ENSMMUG00000054068 COMT ENSMNEG00000022654 COMT ENSPANG00000006826 COMT ENSGGOG00000006699 COMT ENSPPAG00000027543 ENSPTRG00000014070 COMT ENSMICG00000015309 COMT ENSCSAG00000011940 COMT 108406868 COMT ENSRNOG00000001889 Comt ENSMODG00000019644 COMT 108707135 comt.2.S 379402 comt.L 779254 comt.S ENSXETG00000006315 comt ENSXETG00000024946 comt.2 ENSXETG00000033321 foxd1	Compare expression
Sarcopterygii	29 species Mus musculus (mouse) Canis lupus familiaris (dog) Felis catus (cat) Equus caballus (horse) Sus scrofa (pig) Bos taurus (cattle) Capra hircus (Goat) Oryctolagus cuniculus (rabbit) Cavia porcellus (guinea pig) Gallus gallus (chicken) Meleagris gallopavo (Wild turkey) Ornithorhynchus anatinus (platypus) Callithrix jacchus (White-tufted-ear marmoset) Cercocebus atys (Sooty mangabey) Macaca fascicularis (Crab-eating macaque) Macaca mulatta (macaque) Macaca nemestrina (Pig-tailed macaque) Papio anubis (Olive baboon) Gorilla gorilla (gorilla) Pan paniscus (bonobo) Pan troglodytes (chimpanzee) Microcebus murinus (Gray mouse lemur) Chlorocebus sabaeus (Green monkey) Manis javanica (Malayan pangolin) Rattus norvegicus (rat) Monodelphis domestica (opossum) Xenopus laevis (African clawed frog) Xenopus tropicalis (western clawed frog) Latimeria chalumnae (Coelacanth)	33 genes ENSMUSG00000000326 Comt ENSCAFG00000014253 COMT ENSFCAG00000002684 COMT ENSECAG00000005359 COMT ENSSSCG00000010132 COMT ENSBTAG00000019516 COMT ENSCHIG00000006984 COMT ENSOCUG00000006297 COMT ENSCPOG00000004445 COMT ENSGALG00000002024 COMT ENSMGAG00000001429 COMT ENSOANG00000041289 COMT ENSCJAG00000014538 COMT ENSCATG00000026178 COMT ENSMFAG00000030334 COMT ENSMMUG00000054068 COMT ENSMNEG00000022654 COMT ENSPANG00000006826 COMT ENSGGOG00000006699 COMT ENSPPAG00000027543 ENSPTRG00000014070 COMT ENSMICG00000015309 COMT ENSCSAG00000011940 COMT 108406868 COMT ENSRNOG00000001889 Comt ENSMODG00000019644 COMT 108707135 comt.2.S 379402 comt.L 779254 comt.S ENSXETG00000006315 comt ENSXETG00000024946 comt.2 ENSXETG00000033321 foxd1 ENSLACG00000016734 COMT	Compare expression
Euteleostomi	43 species Mus musculus (mouse) Danio rerio (zebrafish) Canis lupus familiaris (dog) Felis catus (cat) Equus caballus (horse) Sus scrofa (pig) Bos taurus (cattle) Capra hircus (Goat) Oryctolagus cuniculus (rabbit) Cavia porcellus (guinea pig) Gallus gallus (chicken) Meleagris gallopavo (Wild turkey) Ornithorhynchus anatinus (platypus) Callithrix jacchus (White-tufted-ear marmoset) Cercocebus atys (Sooty mangabey) Macaca fascicularis (Crab-eating macaque) Macaca mulatta (macaque) Macaca nemestrina (Pig-tailed macaque) Papio anubis (Olive baboon) Gorilla gorilla (gorilla) Pan paniscus (bonobo) Pan troglodytes (chimpanzee) Microcebus murinus (Gray mouse lemur) Chlorocebus sabaeus (Green monkey) Manis javanica (Malayan pangolin) Rattus norvegicus (rat) Monodelphis domestica (opossum) Xenopus laevis (African clawed frog) Xenopus tropicalis (western clawed frog) Lepisosteus oculatus (Spotted gar) Anguilla anguilla (European freshwater eel) Astyanax mexicanus (Blind cave fish) Esox lucius (Northern pike) Salmo salar (Atlantic salmon) Gadus morhua (Atlantic cod) Poecilia reticulata (Guppy) Oryzias latipes (Japanese rice fish) Astatotilapia calliptera (Eastern happy) Neolamprologus brichardi (Fairy cichlid) Scophthalmus maximus (Turbot) Gasterosteus aculeatus (Three-spined stickleback) Nothobranchius furzeri (Turquoise killifish) Latimeria chalumnae (Coelacanth)	51 genes ENSMUSG00000000326 Comt ENSDARG00000015337 comta ENSDARG00000025679 comtb ENSDARG00000111678 comtb ENSCAFG00000014253 COMT ENSFCAG00000002684 COMT ENSECAG00000005359 COMT ENSSSCG00000010132 COMT ENSBTAG00000019516 COMT ENSCHIG00000006984 COMT ENSOCUG00000006297 COMT ENSCPOG00000004445 COMT ENSGALG00000002024 COMT ENSMGAG00000001429 COMT ENSOANG00000041289 COMT ENSCJAG00000014538 COMT ENSCATG00000026178 COMT ENSMFAG00000030334 COMT ENSMMUG00000054068 COMT ENSMNEG00000022654 COMT ENSPANG00000006826 COMT ENSGGOG00000006699 COMT ENSPPAG00000027543 ENSPTRG00000014070 COMT ENSMICG00000015309 COMT ENSCSAG00000011940 COMT 108406868 COMT ENSRNOG00000001889 Comt ENSMODG00000019644 COMT 108707135 comt.2.S 379402 comt.L 779254 comt.S ENSXETG00000006315 comt ENSXETG00000024946 comt.2 ENSXETG00000033321 foxd1 ENSLOCG00000014559 comtb 118208277 comta ENSAMXG00000016773 comta ENSELUG00000004237 comtb ENSELUG00000029048 comta ENSSSAG00000042490 comtb ENSSSAG00000076380 COMT ENSGMOG00000002636 comtb ENSPREG00000021730 comtb ENSORLG00000014228 comtb ENSACLG00000021475 comtb ENSNBRG00000023483 comtb ENSSMAG00000014805 comtb ENSGACG00000012090 comtb ENSNFUG00015013912 COMTB ENSLACG00000016734 COMT	Compare expression
Chordata	44 species Mus musculus (mouse) Danio rerio (zebrafish) Canis lupus familiaris (dog) Felis catus (cat) Equus caballus (horse) Sus scrofa (pig) Bos taurus (cattle) Capra hircus (Goat) Oryctolagus cuniculus (rabbit) Cavia porcellus (guinea pig) Gallus gallus (chicken) Meleagris gallopavo (Wild turkey) Ornithorhynchus anatinus (platypus) Callithrix jacchus (White-tufted-ear marmoset) Cercocebus atys (Sooty mangabey) Macaca fascicularis (Crab-eating macaque) Macaca mulatta (macaque) Macaca nemestrina (Pig-tailed macaque) Papio anubis (Olive baboon) Gorilla gorilla (gorilla) Pan paniscus (bonobo) Pan troglodytes (chimpanzee) Microcebus murinus (Gray mouse lemur) Chlorocebus sabaeus (Green monkey) Manis javanica (Malayan pangolin) Rattus norvegicus (rat) Monodelphis domestica (opossum) Xenopus laevis (African clawed frog) Xenopus tropicalis (western clawed frog) Lepisosteus oculatus (Spotted gar) Anguilla anguilla (European freshwater eel) Astyanax mexicanus (Blind cave fish) Esox lucius (Northern pike) Salmo salar (Atlantic salmon) Gadus morhua (Atlantic cod) Poecilia reticulata (Guppy) Oryzias latipes (Japanese rice fish) Astatotilapia calliptera (Eastern happy) Neolamprologus brichardi (Fairy cichlid) Scophthalmus maximus (Turbot) Gasterosteus aculeatus (Three-spined stickleback) Nothobranchius furzeri (Turquoise killifish) Branchiostoma lanceolatum (Common lancelet) Latimeria chalumnae (Coelacanth)	55 genes ENSMUSG00000000326 Comt ENSDARG00000015337 comta ENSDARG00000025679 comtb ENSDARG00000111678 comtb ENSCAFG00000014253 COMT ENSFCAG00000002684 COMT ENSECAG00000005359 COMT ENSSSCG00000010132 COMT ENSBTAG00000019516 COMT ENSCHIG00000006984 COMT ENSOCUG00000006297 COMT ENSCPOG00000004445 COMT ENSGALG00000002024 COMT ENSMGAG00000001429 COMT ENSOANG00000041289 COMT ENSCJAG00000014538 COMT ENSCATG00000026178 COMT ENSMFAG00000030334 COMT ENSMMUG00000054068 COMT ENSMNEG00000022654 COMT ENSPANG00000006826 COMT ENSGGOG00000006699 COMT ENSPPAG00000027543 ENSPTRG00000014070 COMT ENSMICG00000015309 COMT ENSCSAG00000011940 COMT 108406868 COMT ENSRNOG00000001889 Comt ENSMODG00000019644 COMT 108707135 comt.2.S 379402 comt.L 779254 comt.S ENSXETG00000006315 comt ENSXETG00000024946 comt.2 ENSXETG00000033321 foxd1 ENSLOCG00000014559 comtb 118208277 comta ENSAMXG00000016773 comta ENSELUG00000004237 comtb ENSELUG00000029048 comta ENSSSAG00000042490 comtb ENSSSAG00000076380 COMT ENSGMOG00000002636 comtb ENSPREG00000021730 comtb ENSORLG00000014228 comtb ENSACLG00000021475 comtb ENSNBRG00000023483 comtb ENSSMAG00000014805 comtb ENSGACG00000012090 comtb ENSNFUG00015013912 COMTB BL06050 COMT BL20732 COMT BL96024 COMT BL96025 COMT ENSLACG00000016734 COMT	Compare expression

Showing 1 to 13 of 13 entries

Orthology information comes from OMA : ENSG00000093010.

Paralogs (same species)

Filter:

Taxon Name	Gene(s)	Expression comparison	See details
Opisthokonta	2 genes ENSG00000284844 AP000812.3 ENSG00000284922 AP000812.4	Compare expression: table \| graph

Showing 1 to 1 of 1 entries

Paralogy information comes from OMA : ENSG00000093010.

Cross-references

CCDS

CCDS13770 (CCDS13770.1),CCDS46663 (CCDS46663.1)

Ensembl

ENSG00000093010 (COMT)

HGNC

HGNC:2228 (COMT)

EMBL

AC000080,AC000090,AC005663,AK290440,AY341246,BC000419,BC005867,BC011935

GeneCards

ENSG00000093010

UniProtKB/Swiss-Prot

COMT_HUMAN,P21964

UniProtKB/TrEMBL

A0A7I2V370,A0A7I2V370_HUMAN,A0A7I2V3G7,A0A7I2V3G7_HUMAN,E7EMS6,E7EMS6_HUMAN,E7EUU8,E7EUU8_HUMAN